August, 2017 update

    • LIPID MAPS® Highlights

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    • Lipid of the month


      ALA

      Alpha-linolenic acid or ALA (systematic Name: 9Z,12Z,15Z-octadecatrienoic acid) is an unsaturated fatty acid found primarily in seeds and vegetable oils. ALA is categorized as an omega-3 fatty acid, and is an isomer of gamma-linolenic acid, which is a polyunsaturated omega-6 fatty acid. It is an essential fatty acid because it is necessary for health and cannot be produced within the human body. ALA can only be obtained by humans through their diets because the absence of the required 12- and 15-desaturase enzymes makes de novo synthesis from stearic acid or oleic acid impossible.

      Lipid of the month archive

"Lipid Matters - A Personal Blog" — by William (Bill) W. Christie

August 23nd, 2017

It is now commonplace to learn of how lipids are involved in various human disease states from the standpoint of errors in metabolism. On the other hand, there is recent evidence that bacteria and their lipids may be involved in what were formerly considered purely metabolic diseases. For example, it has now been reported that significant amounts of rhamnolipids are found in serum from patients with Alzheimer's disease . . .

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Key LIPID MAPS® Resources
Publications
- publications related to projects funded through the LIPID MAPS® consortium
Lipid Classification System
- the first internationally accepted lipid classification system
Lipid Standards
- MS/MS spectra, annotations for principal product ions, and acquisition parameters
Experimental Data
- centralized studies on macrophages, lipidomics data on human plasma, and more
Structure Database (LMSD)
- over 40,000 unique structures of biologically relevant lipids
Proteome Database (LMPD)
- over 12,500 lipid-associated proteins from major research species
Pathways
- manually curated lipid metabolism and signaling pathways
LIPID MAPS® REST Service
- web-based/programmatic access to lipid structure and lipid-related gene/protein data
MS analysis tools
- tools for searching various lipid classes by precursor or product ion
Structure Drawing Tools
- draw and save lipid structures using online menus
Protocols
- LIPID MAPS® techniques for lipidomics and macrophage cell culture

LIPID MAPS® is funded by a grant from the Wellcome Trust.

logo LIPID MAPS® is funded by a grant from the Wellcome Trust.