December, 2017 update

Please note: The LIPID MAPS Lipidomics Gateway will be temporarily unavailable beginning Monday, December 11, 2017 10AM PST while we conduct server maintenance, which we expect to be completed by 2PM PST. We apologize for any inconvenience.


    • Lipid of the month

      UCDA

      Ursodeoxycholic acid or ursodiol (sytematic name: 3alpha,7beta-dihydroxy-5beta-cholan-24-oic acid) is a 24-carbon secondary bile acid, which are metabolic byproducts of intestinal bacteria. Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. Because of this property, ursodeoxycholic acid is used to treat (cholesterol) gallstones non-surgically. Ursodeoxycholic acid has also been shown experimentally to suppress immune response such as immune cell phagocytosis.

      Lipid of the month archive

"Lipid Matters - A Personal Blog" — by William (Bill) W. Christie

Dec 06th, 2017

Most readers today will not need me to explain the importance of lipid mediators in biology, but this was not always so. I recall attending an ICBL Congress in 1968 when a keynote speaker described prostaglandins as "a drug in search of a disease"! (The only virtue of growing older is that you remember such things). The earliest true pharmaceutical to come into general use and probably still that most widely used is aspirin, …

more lipid matters



Key LIPID MAPS® Resources
Publications
- publications related to projects funded through the LIPID MAPS® consortium
Lipid Classification System
- the first internationally accepted lipid classification system
Lipid Standards
- MS/MS spectra, annotations for principal product ions, and acquisition parameters
Experimental Data
- centralized studies on macrophages, lipidomics data on human plasma, and more
Structure Database (LMSD)
- over 40,000 unique structures of biologically relevant lipids
Proteome Database (LMPD)
- over 12,500 lipid-associated proteins from major research species
Pathways
- manually curated lipid metabolism and signaling pathways
LIPID MAPS® REST Service
- web-based/programmatic access to lipid structure and lipid-related gene/protein data
MS analysis tools
- tools for searching various lipid classes by precursor or product ion
Structure Drawing Tools
- draw and save lipid structures using online menus
Protocols
- LIPID MAPS® techniques for lipidomics and macrophage cell culture

LIPID MAPS® is funded by a grant from the Wellcome Trust.

logo LIPID MAPS® is funded by a grant from the Wellcome Trust.