LIPID MAPS® Highlights — July, 2018
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It has become commonplace to see new reports of the biochemistry of oxylipins derived from the C20 and C22 polyunsaturated fatty acids, and it is easy to forget that there are some important metabolites of the more simple C18 fatty acids. In particular, I am thinking of the nitro fatty acids derived from oleate and linoleate …
Sphingomyelins, such as SM(d18:1/16:0) (systematic name: N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine) are a class of sphingolipids composed of the long-chain sphingosine base attached to a fatty acid via an N-acyl linkage and a phosphocholine head group. In humans, sphingomyelins represent ~85% of all sphingolipids, and typically make up 10-20 mol % of plasma membrane lipids. They resemble phosphatidylcholines in their general properties and three-dimensional structure, and in having no net charge on their head groups. …
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