LMPD Database

LMP000139

Gene Information

Entrez Gene ID	11807
Gene Name	apolipoprotein A-II
Gene Symbol	Apoa2
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0072562	IEA:Ensembl	C	blood microparticle
GO:0042627	IEA:Ensembl	C	chylomicron
GO:0005829	TAS:Reactome	C	cytosol
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:MGI	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0034366	IEA:Ensembl	C	spherical high-density lipoprotein particle
GO:0034361	IEA:Ensembl	C	very-low-density lipoprotein particle
GO:0015485	IEA:Ensembl	F	cholesterol binding
GO:0017127	IEA:Ensembl	F	cholesterol transporter activity
GO:0008035	IMP:MGI	F	high-density lipoprotein particle binding
GO:0055102	IEA:Ensembl	F	lipase inhibitor activity
GO:0031210	IEA:Ensembl	F	phosphatidylcholine binding
GO:0060228	IEA:Ensembl	F	phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0046982	ISS:UniProtKB	F	protein heterodimerization activity
GO:0002526	IEA:Ensembl	P	acute inflammatory response
GO:0015759	NAS:UniProtKB	P	beta-glucoside transport
GO:0033344	IEA:Ensembl	P	cholesterol efflux
GO:0042632	IDA:MGI	P	cholesterol homeostasis
GO:0008203	IMP:MGI	P	cholesterol metabolic process
GO:0046340	IEA:Ensembl	P	diacylglycerol catabolic process
GO:0006631	NAS:UniProtKB	P	fatty acid metabolic process
GO:0034380	IEA:Ensembl	P	high-density lipoprotein particle assembly
GO:0034384	IEA:Ensembl	P	high-density lipoprotein particle clearance
GO:0034375	IEA:Ensembl	P	high-density lipoprotein particle remodeling
GO:0006869	IMP:MGI	P	lipid transport
GO:0042157	IDA:MGI	P	lipoprotein metabolic process
GO:0034374	IEA:Ensembl	P	low-density lipoprotein particle remodeling
GO:0060621	IEA:Ensembl	P	negative regulation of cholesterol import
GO:0060695	IEA:Ensembl	P	negative regulation of cholesterol transporter activity
GO:0002740	IEA:Ensembl	P	negative regulation of cytokine secretion involved in immune response
GO:0060192	IMP:MGI	P	negative regulation of lipase activity
GO:0050995	IEA:Ensembl	P	negative regulation of lipid catabolic process
GO:0010903	IEA:Ensembl	P	negative regulation of very-low-density lipoprotein particle remodeling
GO:0031100	IEA:Ensembl	P	organ regeneration
GO:0018206	IEA:Ensembl	P	peptidyl-methionine modification
GO:0006656	IEA:Ensembl	P	phosphatidylcholine biosynthetic process
GO:0009395	IEA:Ensembl	P	phospholipid catabolic process
GO:0033700	IEA:Ensembl	P	phospholipid efflux
GO:0010873	IEA:Ensembl	P	positive regulation of cholesterol esterification
GO:0045416	ISS:UniProtKB	P	positive regulation of interleukin-8 biosynthetic process
GO:0050996	IEA:Ensembl	P	positive regulation of lipid catabolic process
GO:0006457	IEA:Ensembl	P	protein folding
GO:0018158	IEA:Ensembl	P	protein oxidation
GO:0030300	IMP:MGI	P	regulation of intestinal cholesterol absorption
GO:0031647	IEA:Ensembl	P	regulation of protein stability
GO:0042493	IEA:Ensembl	P	response to drug
GO:0043627	IEA:Ensembl	P	response to estrogen
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0043691	IEA:Ensembl	P	reverse cholesterol transport
GO:0034370	IEA:Ensembl	P	triglyceride-rich lipoprotein particle remodeling

KEGG Pathway Links

KEGG Pathway ID	Description
mmu03320	PPAR signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
5893389	Chylomicron-mediated lipid transport
5893843	PPARA activates gene expression