LMPD Database

LMP000283

Gene Information

Entrez Gene ID2629
Gene Nameglucosidase, beta, acid
Gene SymbolGBA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043202 ISS:BHF-UCLClysosomal lumen
GO:0005765 IDA:UniProtKBClysosomal membrane
GO:0004348 IDA:BHF-UCLFglucosylceramidase activity
GO:0005102 ISS:BHF-UCLFreceptor binding
GO:0005975 IEA:InterProPcarbohydrate metabolic process
GO:0008219 IEA:UniProtKB-KWPcell death
GO:0071356 IMP:BHF-UCLPcellular response to tumor necrosis factor
GO:0046513 IMP:BHF-UCLPceramide biosynthetic process
GO:0006680 IMP:BHF-UCLPglucosylceramide catabolic process
GO:0006687 TAS:ReactomePglycosphingolipid metabolic process
GO:0050728 IC:BHF-UCLPnegative regulation of inflammatory response
GO:0032715 IDA:BHF-UCLPnegative regulation of interleukin-6 production
GO:0043407 IMP:BHF-UCLPnegative regulation of MAP kinase activity
GO:0035307 IMP:BHF-UCLPpositive regulation of protein dephosphorylation
GO:0033561 IEA:EnsemblPregulation of water loss via skin
GO:0043627 IEA:EnsemblPresponse to estrogen
GO:0051384 IEA:EnsemblPresponse to glucocorticoid
GO:0009268 IEA:EnsemblPresponse to pH
GO:0033574 IEA:EnsemblPresponse to testosterone
GO:0097066 IEA:EnsemblPresponse to thyroid hormone
GO:0043589 IEA:EnsemblPskin morphogenesis
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 TAS:ReactomePsphingolipid metabolic process
GO:0046512 IMP:BHF-UCLPsphingosine biosynthetic process
GO:0023021 IMP:BHF-UCLPtermination of signal transduction
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04142Lysosome
hsa01100Metabolic pathways
hsa00600Sphingolipid metabolism
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116105Glycosphingolipid metabolism