LMPD Database

LMP000402

Record overview

LMPD IDLMP000402
Gene ID341
SpeciesHomo sapiens (Human)
Gene Nameapolipoprotein C-I
Gene SymbolAPOC1
SynonymsApo-CI; ApoC-I
Alternate namesapolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1; apolipoprotein C-I variant I
Chromosome19
Map Location19q13.2
SummaryThe protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for APOC1

Proteins

apolipoprotein C-I precursor
Refseq ID:NP_001636
Protein GI:4502157
UniProt ID:P02654
mRNA ID:NM_001645
Length:83
RefSeq Status:REVIEWED
MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS
 
sig_peptide: 1..26
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2719
peptide sequence: 
MRLFLSLPVLVVVLSIVLEGPAPAQG

mat_peptide: 27..83
product: apolipoprotein C-I
calculated_mol_wt: 6631
peptide sequence: 
TPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS