LMPD Database

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LMP000693

UniProt Annotations

Entry Information
Gene Nameacyloxyacyl hydrolase (neutrophil)
Protein EntryAOAH_HUMAN
UniProt IDP28039
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P28039-1; Sequence=Displayed; Name=2; IsoId=P28039-2; Sequence=VSP_042571; Note=No experimental confirmation available.;
Catalytic Activity3-(acyloxy)acyl group of bacterial toxin = 3- hydroxyacyl group of bacterial toxin + a fatty acid.
FunctionRemoves the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides.
PtmBoth subunits contain a number of cysteine residues that may form disulfide bridges.
SimilarityContains 1 saposin B-type domain.
Subcellular LocationSecreted.
SubunitHeterodimer.