LMPD Database

LMP001747

UniProt Annotations

Entry Information
Gene Namelipopolysaccharide binding protein
Protein EntryLBP_MOUSE
UniProt IDQ61805
SpeciesMouse
Comments
Comment typeDescription
FunctionBinds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (By similarity). {ECO:0000250}.
SimilarityBelongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitWhen bound to LPS, interacts (via C-terminus) with soluble CD14. {ECO:0000250}.