LMPD Database

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LMP001937

Record overview

LMPD IDLMP001937
Gene ID887
SpeciesHomo sapiens (Human)
Gene Namecholecystokinin B receptor
Gene SymbolCCKBR
SynonymsCCK-B; CCK2R; GASR
Alternate namesgastrin/cholecystokinin type B receptor; CCK-BR; CCK2-R; CCK2 receptor; CCK-B receptor; gastrin receptor; cholecystokinin-2 receptor
Chromosome11
Map Location11p15.4
SummaryThis gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CCKBR

Proteins

gastrin/cholecystokinin type B receptor
Refseq ID:NP_795344
Protein GI:28875799
UniProt ID:P32239
mRNA ID:NM_176875
Length:447
RefSeq Status:REVIEWED
MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSD
LLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGP
RVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQA
CLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG