LMPD Database

LMP002013

Record overview

LMPD ID	LMP002013
Gene ID	5919
Species	Homo sapiens (Human)
Gene Name	retinoic acid receptor responder (tazarotene induced) 2
Gene Symbol	RARRES2
Synonyms	HP10433; TIG2
Alternate names	retinoic acid receptor responder protein 2; chemerin; RAR-responsive protein TIG2; tazarotene-induced gene 2 protein
Chromosome	7
Map Location	7q36.1
Summary	This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi. [provided by RefSeq, Nov 2014]
Orthologs	View orthologs and multiple alignments for RARRES2

Proteins

retinoic acid receptor responder protein 2 precursor

Refseq ID:	NP_002880
Protein GI:	4506427
UniProt ID:	Q99969
mRNA ID:	NM_002889
Length:	163
RefSeq Status:	REVIEWED

`MRRLLIPLALWLGAVGVGVAELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLA CIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFSKALPRS`

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2106
peptide sequence: 
MRRLLIPLALWLGAVGVGVA

mat_peptide: 21..157
product: retinoic acid receptor responder protein 2
experiment: DESCRIPTION:antimicrobial peptide[PMID: 24660117]
calculated_mol_wt: 15877
peptide sequence: 
ELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIE
TQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFS