LMPD Database

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LMP002081

Record overview

LMPD IDLMP002081
Gene ID14595
SpeciesMus musculus(Mouse)
Gene NameUDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Gene SymbolB4galt1
SynonymsB-1,4-GalT; B-1,4-GalT1; GalT; Ggtb; Ggtb2; b4Gal-T1; beta-1,4-GalT; beta-1,4-GalT1; beta4Gal-T1
Alternate namesbeta-1,4-galactosyltransferase 1; beta-1,4-GalTase 1; b1,4-Galactosyltransferase I; galactosyltransferase 2 beta 1, 4; glycoprotein galactosyltransferase beta 1, 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
Chromosome4
Map Location4 A5|4 20.46 cM
EC Number2.4.1.-
SummaryThis gene encodes two distinct enzyme isoforms, a long membrane-bound form and a short soluble form. These alternate isoforms are thought to be produced through alternative nested transcription initiation and different in-frame start codon usage. These enzymes catalyze the transfer of galactose to acceptor sugars, such as N-acetylglucosamine and glucose. The long form of this enzyme is localized to the trans-Golgi membrane and is involved in glycoconjugate biosynthesis. The short form functions in lactose biosynthesis though formation of a heterodimer with alpha-lactalbumin. [provided by RefSeq, Nov 2012]
OrthologsView orthologs and multiple alignments for B4galt1

Proteins

beta-1,4-galactosyltransferase 1
Refseq ID:NP_071641
Protein GI:11602910
UniProt ID:P15535
mRNA ID:NM_022305
Length:399
RefSeq Status:REVIEWED
MRFREQFLGGSAAMPGATLQRACRLLVAVCALHLGVTLVYYLSGRDLSRLPQLVGVSSTLQGGTNGAAASKQPPGEQRPRGARPPPPLGVSPKPRPGLDS
SPGAASGPGLKSNLSSLPVPTTTGLLSLPACPEESPLLVGPMLIDFNIAVDLELLAKKNPEIKTGGRYSPKDCVSPHKVAIIIPFRNRQEHLKYWLYYLH
PILQRQQLDYGIYVINQAGDTMFNRAKLLNIGFQEALKDYDYNCFVFSDVDLIPMDDRNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLA
INGFPNNYWGWGGEDDDIFNRLVHKGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMRFDGLNSLTYKVLDVQRYPLYTQITVDIGTPR