LMPD Database

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LMP002172

Record overview

LMPD IDLMP002172
Gene ID6715
SpeciesHomo sapiens (Human)
Gene Namesteroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Gene SymbolSRD5A1
SynonymsS5AR 1
Alternate names3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; 5-alpha reductase; steroid 5-alpha-reductase 1; steroid 5-alpha-reductase type I; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1
Chromosome5
Map Location5p15
EC Number1.3.1.22
SummarySteroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for SRD5A1

Proteins

3-oxo-5-alpha-steroid 4-dehydrogenase 1
Refseq ID:NP_001038
Protein GI:4507201
UniProt ID:P18405
mRNA ID:NM_001047
Length:259
RefSeq Status:VALIDATED
MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCL
IYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYF
GEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF