LMPD Database

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LMP002333

Record overview

LMPD IDLMP002333
Gene ID8416
SpeciesHomo sapiens (Human)
Gene Nameannexin A9
Gene SymbolANXA9
SynonymsANX31
Alternate namesannexin A9; annexin-9; pemphaxin; annexin 31; annexin-31; annexin XXXI
Chromosome1
Map Location1q21
SummaryThe annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ANXA9

Proteins

annexin A9
Refseq ID:NP_003559
Protein GI:145864465
UniProt ID:O76027
mRNA ID:NM_003568
Length:345
RefSeq Status:VALIDATED
MSVTGGKMAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALS
GNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAE
QDVQALQRAEGPSREETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISR
CETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAEDM