LMPD Database

LMP002474

Record overview

LMPD IDLMP002474
Gene ID57105
SpeciesHomo sapiens (Human)
Gene Namecysteinyl leukotriene receptor 2
Gene SymbolCYSLTR2
SynonymsCYSLT2; CYSLT2R; HG57; HPN321; KPG_011; hGPCR21
Chromosome13
Map Location13q14.2
SummaryThe cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CYSLTR2

Proteins

cysteinyl leukotriene receptor 2
Refseq ID:NP_065110
Protein GI:9966851
UniProt ID:Q5KU17
mRNA ID:NM_020377
Length:346
RefSeq Status:REVIEWED
MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLR
GSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQT
MNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACF
NPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV