LMPD Database

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LMP002819

Record overview

LMPD IDLMP002819
Gene ID74442
SpeciesMus musculus(Mouse)
Gene Namesphingomyelin synthase 2
Gene SymbolSgms2
Synonyms4933405A16Rik; 5133401H06Rik; AI854299
Chromosome3
Map Location3 G3|3
SummarySphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. [provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for Sgms2

Proteins

phosphatidylcholine:ceramide cholinephosphotransferase 2
Refseq ID:NP_083219
Protein GI:27229211
UniProt ID:Q9D4B1
mRNA ID:NM_028943
Length:365
RefSeq Status:REVIEWED
MDIIETAKLEGHLESQTNDSTNTYTSPTEAVEEEGKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSKNKFPLEWWKTGIAFVYALFNLILTTVMITVV
HERVPPKELSPPLPDKFFDYFDRVKWAFSVSEINGMVLVGLWITQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKI
QRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNL
KVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCRKYSRVQKIGEDNEKST