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LMP002997

Record overview

LMPD IDLMP002997
Gene ID51170
SpeciesHomo sapiens (Human)
Gene Namehydroxysteroid (17-beta) dehydrogenase 11
Gene SymbolHSD17B11
Synonyms17-BETA-HSD11; 17-BETA-HSDXI; 17BHSD11; DHRS8; PAN1B; RETSDR2; SDR16C2
Alternate namesestradiol 17-beta-dehydrogenase 11; CTCL tumor antigen HD-CL-03; CTCL-associated antigen HD-CL-03; dehydrogenase/reductase SDR family member 8; 17-beta-hydroxysteroid dehydrogenase type XI; retinal short-chain dehydrogenase/reductase 2; cutaneous T-cell lymphoma-associated antigen HD-CL-03; short chain dehydrogenase/reductase family 16C, member 2
Chromosome4
Map Location4q22.1
EC Number1.1.1.62
SummaryShort-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
OrthologsView orthologs and multiple alignments for HSD17B11

Proteins

estradiol 17-beta-dehydrogenase 11 precursor
Refseq ID:NP_057329
Protein GI:613410229
UniProt ID:Q8NBQ5
mRNA ID:NM_016245
Length:300
RefSeq Status:VALIDATED
MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDI
YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLT
DELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2171
peptide sequence: 
MKFLLDILLLLPLLIVCSL

mat_peptide: 20..300
product: Estradiol 17-beta-dehydrogenase 11
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q8NBQ5.3)
calculated_mol_wt: 30811
peptide sequence: 
ESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVN
NAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN
FVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ