LMPD Database

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LMP004643

UniProt Annotations

Entry Information
Gene Nameprenylcysteine oxidase 1
Protein EntryPCYOX_HUMAN
UniProt IDQ9UHG3
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9UHG3-1; Sequence=Displayed; Name=2; IsoId=Q9UHG3-2; Sequence=VSP_056701; Note=No experimental confirmation available.;
Catalytic ActivityAn S-prenyl-L-cysteine + O(2) + H(2)O = a prenal + L-cysteine + H(2)O(2).
CautionWas originally thought to be a lyase and was therefore termed prenylcysteine lyase.
CofactorName=FAD; Xref=ChEBI
FunctionInvolved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.
PtmThe protein is glycosylated at one or more potential N- glycosylation sites. {ECO
Sequence CautionSequence=BAA74931.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the prenylcysteine oxidase family.
Subcellular LocationLysosome.
Tissue SpecificityUbiquitous.