LMPD Database

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LMP004975

Record overview

LMPD IDLMP004975
Gene ID157506
SpeciesHomo sapiens (Human)
Gene Nameretinol dehydrogenase 10 (all-trans)
Gene SymbolRDH10
SynonymsSDR16C4
Alternate namesretinol dehydrogenase 10; short chain dehydrogenase/reductase family 16C, member 4
Chromosome8
Map Location8q21.11
EC Number1.1.1.300
SummaryThis gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
OrthologsView orthologs and multiple alignments for RDH10

Proteins

retinol dehydrogenase 10
Refseq ID:NP_742034
Protein GI:25282469
UniProt ID:Q8IZV5
mRNA ID:NM_172037
Length:341
RefSeq Status:REVIEWED
MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNG
EEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLG
LFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMK
SILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI