LMPD Database

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LMP005434

Record overview

LMPD IDLMP005434
Gene ID22901
SpeciesHomo sapiens (Human)
Gene Namearylsulfatase G
Gene SymbolARSG
Synonyms-
Alternate namesarylsulfatase G; ASG
Chromosome17
Map Location17q24.2
EC Number3.1.6.-
SummaryThe protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
OrthologsView orthologs and multiple alignments for ARSG

Proteins

arylsulfatase G
Refseq ID:NP_001254656
Protein GI:392050740
UniProt ID:Q96EG1
mRNA ID:NM_001267727
Length:525
RefSeq Status:REVIEWED
MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRN
GVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVA
LPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFT
GDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQ
PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISS
ADYTQDPSVTPCCNPYQIACRCQAA
 
arylsulfatase G
Refseq ID:NP_055775
Protein GI:45430057
UniProt ID:Q96EG1
mRNA ID:NM_014960
Length:525
RefSeq Status:REVIEWED
Protein sequence is identical to GI:392050740 (mRNA isoform)