LMPD Database

LMP007260

UniProt Annotations

Entry Information
Gene Namelong-chain fatty acid-CoA ligase FAA4
Protein EntryLCF4_YEAST
UniProt IDP47912
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ;
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
FunctionEsterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Contributes, with FAA1, to the activation of imported myristate.
MiscellaneousPresent with 31200 molecules/cell in log phase SD medium
MiscellaneousPresent with 31200 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.