LMPD Database

LMP007392

UniProt Annotations

Entry Information
Gene Namelong-chain fatty acid-CoA ligase FAA3
Protein EntryLCF3_YEAST
UniProt IDP39002
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiesTemperature dependence: Optimum temperature is 25 degrees Celsius.;
Biophysicochemical PropertiesTemperature dependence: Optimum temperature is 25 degrees Celsius.;
Catalytic ActivityATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ;
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
FunctionEsterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. This enzyme acts preferentially on C16 and C18 fatty acids with a cis-double bond at C-9-C-10.
MiscellaneousPresent with 6440 molecules/cell in log phase SD medium
MiscellaneousPresent with 6440 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
SubunitInteracts with FRK1
SubunitInteracts with FRK1. {ECO:0000269|PubMed:20489023}.