LMPD Database

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LMP007447

UniProt Annotations

Entry Information
Gene Nameglycerol-3-phosphate dehydrogenase (NAD(+)) GPD1
Protein EntryGPD1_YEAST
UniProt IDQ00055
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activitysn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
CautionWas originally thought to be GUT2, the FAD-dependent glycerol-3-phosphate dehydrogenase
CautionWas originally thought to be GUT2, the FAD-dependent glycerol-3-phosphate dehydrogenase. {ECO:0000305|PubMed:1676389}.
FunctionCatalyzes the production and accumulation of glycerol during hyperosmotic stress conditions. Glycerol acts as a osmoregulator that prevents loss of water and turgor of the cells
FunctionCatalyzes the production and accumulation of glycerol during hyperosmotic stress conditions. Glycerol acts as a osmoregulator that prevents loss of water and turgor of the cells. {ECO:0000269|PubMed:8196651}.
InductionBy osmotic stress and by methylglyoxal in a HOG pathway-dependent manner. {ECO:0000269|PubMed:15773992, ECO:0000269|PubMed:8196651}.
MiscellaneousPresent with 807 molecules/cell in log phase SD medium
MiscellaneousPresent with 807 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family
SimilarityBelongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. {ECO:0000305}.
Subcellular LocationCytoplasm. Peroxisome.