LMPD Database

LMP009785

Record overview

LMPD IDLMP009785
Gene ID824347
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Nameacyl-coenzyme A oxidase 4
Gene SymbolACX4
Synonymsacyl-CoA oxidase 4; ATG6; ATSCX; SHORT-CHAIN ACYL COA OXIDASE
Alternate namesacyl-coenzyme A oxidase 4
Chromosome3
EC Number1.3.3.6
SummaryEncodes a short-chain acyl-CoA oxidase, which catalyzes the first step of peroxisomal fatty acid beta-oxidation during early, post-germinative growth in oilseed species. Null mutants virtually lack short-chain acyl-CoA and are resistant to 2,4-dichlorophenoxybutyric acid, which is converted to the herbicide and auxin analogue 2,4-dichlorophenoxyacetic acid by beta-oxidation. Despite the almost complete loss of short-chain activity, lipid catabolism and seedling growth and establishment was unaltered in the acx4 mutant. However, double mutants in acx3acx4 (acx3 encodes medium chain acyl CoA oxidase) were not viable and arrested during embryogenesis.
OrthologsView orthologs and multiple alignments for ACX4

Proteins

acyl-coenzyme A oxidase 4
Refseq ID:NP_190752
Protein GI:15231059
UniProt ID:Q96329
mRNA ID:NM_115043
Length:436
RefSeq Status:REVIEWED
MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGV
AGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKIN
GQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM
GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCD
LEPIYTYEGTYDINTLVTGREVTGIASFKPATRSRL