LMPD Database

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LMP010418

UniProt Annotations

Entry Information
Gene Nameglycerol-3-phosphate dehydrogenase [NAD(+)] 2
Protein EntryGPDA2_ARATH
UniProt IDQ949Q0
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.33 uM for glycerone phosphate {ECO:0000269|PubMed:22645576}; Vmax=49 umol/min/mg enzyme toward glycerone phosphate {ECO:0000269|PubMed:22645576};
Catalytic Activitysn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. {ECO:0000269|PubMed:14729910, ECO:0000269|PubMed:15044700, ECO:0000269|PubMed:22645576}.
Disruption PhenotypeNo visible phenotype under normal growth conditions, but leaves have decreased levels of hexadecatrienoic fatty acid (16:3) and increased levels of oleic acid (18:1). {ECO:0000269|PubMed:14729910, ECO:0000269|PubMed:15044700}.
FunctionRequired to supply glycerol-3-phosphate in the chloroplast for the synthesis of glycerolipids. Required for activation of systemic acquired resistance (SAR). Provision of glycerol-3-phosphate may be involved in generating lipid signals necessary for mediating defense responses and SAR. {ECO:0000269|PubMed:14729910, ECO:0000269|PubMed:15044700, ECO:0000269|PubMed:17431038, ECO:0000269|PubMed:18088304, ECO:0000269|PubMed:22645576}.
PathwayMembrane lipid metabolism; glycerophospholipid metabolism.
SimilarityBelongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast {ECO:0000250}.