LMPD Database

LMP012594

Gene Information

Entrez Gene ID	29469
Gene Name	lipopolysaccharide binding protein
Gene Symbol	Lbp
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IEA:Ensembl	C	cell surface
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0001530	IEA:Ensembl	F	lipopolysaccharide binding
GO:0070891	IEA:Ensembl	F	lipoteichoic acid binding
GO:0006953	IEA:Ensembl	P	acute-phase response
GO:0071223	IEA:Ensembl	P	cellular response to lipoteichoic acid
GO:0050829	IEA:Ensembl	P	defense response to Gram-negative bacterium
GO:0050830	IEA:Ensembl	P	defense response to Gram-positive bacterium
GO:0032490	IEA:Ensembl	P	detection of molecule of bacterial origin
GO:0045087	IEA:Ensembl	P	innate immune response
GO:0002232	IEA:Ensembl	P	leukocyte chemotaxis involved in inflammatory response
GO:0031663	IEA:Ensembl	P	lipopolysaccharide-mediated signaling pathway
GO:0015920	IEA:Ensembl	P	lipopolysaccharide transport
GO:0002281	IEA:Ensembl	P	macrophage activation involved in immune response
GO:0044130	IEA:Ensembl	P	negative regulation of growth of symbiont in host
GO:0032720	IEA:Ensembl	P	negative regulation of tumor necrosis factor production
GO:0032722	IEA:Ensembl	P	positive regulation of chemokine production
GO:0032755	IEA:Ensembl	P	positive regulation of interleukin-6 production
GO:0032757	IEA:Ensembl	P	positive regulation of interleukin-8 production
GO:0043032	IEA:Ensembl	P	positive regulation of macrophage activation
GO:0090023	IEA:Ensembl	P	positive regulation of neutrophil chemotaxis
GO:0060265	IEA:Ensembl	P	positive regulation of respiratory burst involved in inflammatory response
GO:0034145	IEA:Ensembl	P	positive regulation of toll-like receptor 4 signaling pathway
GO:0042535	IEA:Ensembl	P	positive regulation of tumor necrosis factor biosynthetic process
GO:0032760	IEA:Ensembl	P	positive regulation of tumor necrosis factor production

KEGG Pathway Links

KEGG Pathway ID	Description
rno04064	NF-kappa B signaling pathway
ko05132	Salmonella infection
rno05132	Salmonella infection
ko04620	Toll-like receptor signaling pathway
rno04620	Toll-like receptor signaling pathway
ko05152	Tuberculosis
rno05152	Tuberculosis

REACTOME Pathway Links

REACTOME Pathway ID	Description
5953410	Immune System
5953409	Innate Immune System
5953552	Toll Like Receptor 4 (TLR4) Cascade
5953553	Toll-Like Receptors Cascades
5953771	Transfer of LPS from LBP carrier to CD14