LMPD Database

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LMP012642

Gene Information

Entrez Gene ID50671
Gene Namefatty acid synthase
Gene SymbolFasn
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IEA:EnsemblCextracellular vesicular exosome
GO:0042587 IEA:EnsemblCglycogen granule
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005886 IEA:EnsemblCplasma membrane
GO:0047451 IEA:UniProtKB-ECF3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0004317 IEA:InterProF3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004316 IEA:UniProtKB-ECF3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004315 IEA:UniProtKB-ECF3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004313 IEA:UniProtKB-ECF[acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 IEA:UniProtKB-ECF[acyl-carrier-protein] S-malonyltransferase activity
GO:0008144 IDA:RGDFdrug binding
GO:0047117 IEA:UniProtKB-ECFenoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0004319 IEA:InterProFenoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004312 IDA:RGDFfatty acid synthase activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0016295 IEA:UniProtKB-ECFmyristoyl-[acyl-carrier-protein] hydrolase activity
GO:0070402 IDA:RGDFNADPH binding
GO:0004320 IEA:UniProtKB-ECFoleoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 IEA:UniProtKB-ECFpalmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0044822 IEA:EnsemblFpoly(A) RNA binding
GO:0042803 IDA:RGDFprotein homodimerization activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0006084 IDA:RGDPacetyl-CoA metabolic process
GO:0071353 IEA:EnsemblPcellular response to interleukin-4
GO:0006633 IMP:RGDPfatty acid biosynthetic process
GO:0008610 TAS:RGDPlipid biosynthetic process
GO:0001649 IEA:EnsemblPosteoblast differentiation
KEGG Pathway Links
KEGG Pathway IDDescription
ko04152AMPK signaling pathway
rno04152AMPK signaling pathway
ko00061Fatty acid biosynthesis
rno00061Fatty acid biosynthesis
M00083Fatty acid biosynthesis, elongation
M00082Fatty acid biosynthesis, initiation
ko01212Fatty acid metabolism
rno01212Fatty acid metabolism
ko04910Insulin signaling pathway
rno04910Insulin signaling pathway
rno01100Metabolic pathways
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954496Activation of gene expression by SREBF (SREBP)
5953760ChREBP activates metabolic gene expression
5953298Defective AMN causes hereditary megaloblastic anemia 1
5953308Defective BTD causes biotidinase deficiency
5953307Defective CD320 causes methylmalonic aciduria
5953299Defective CUBN causes hereditary megaloblastic anemia 1
5953296Defective GIF causes intrinsic factor deficiency
5953310Defective HLCS causes multiple carboxylase deficiency
5953297Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
5953305Defective MMAA causes methylmalonic aciduria type cblA
5953302Defective MMAB causes methylmalonic aciduria type cblB
5953304Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
5953303Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
5953301Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
5953300Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
5953306Defective MUT causes methylmalonic aciduria mut type
5953293Defective TCN2 causes hereditary megaloblastic anemia
5953309Defects in biotin (Btn) metabolism
5953294Defects in cobalamin (B12) metabolism
5953295Defects in vitamin and cofactor metabolism
5953253Disease
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953463Fatty Acyl-CoA Biosynthesis
5953611Integration of energy metabolism
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5953292Metabolism of vitamins and cofactors
5953291Metabolism of water-soluble vitamins and cofactors
5954497Regulation of cholesterol biosynthesis by SREBP (SREBF)
5953464Triglyceride Biosynthesis
5953985Vitamin B5 (pantothenate) metabolism