LMPD Database

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LMP012745

Gene Information

Entrez Gene ID79238
Gene Name3-hydroxymethyl-3-methylglutaryl-CoA lyase
Gene SymbolHmgcl
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005739 IDA:RGDCmitochondrion
GO:0005777 IEA:UniProtKB-KWCperoxisome
GO:0031406 IPI:RGDFcarboxylic acid binding
GO:0000062 IPI:RGDFfatty-acyl-CoA binding
GO:0004419 ISS:UniProtKBFhydroxymethylglutaryl-CoA lyase activity
GO:0000287 IEA:EnsemblFmagnesium ion binding
GO:0030145 IEA:EnsemblFmanganese ion binding
GO:0046872 ISS:UniProtKBFmetal ion binding
GO:0006637 IDA:RGDPacyl-CoA metabolic process
GO:0046951 IDA:RGDPketone body biosynthetic process
GO:0001889 IEP:RGDPliver development
GO:0007005 IEA:EnsemblPmitochondrion organization
GO:0051262 IEA:EnsemblPprotein tetramerization
GO:0070542 IEP:RGDPresponse to fatty acid
GO:0007584 IEP:RGDPresponse to nutrient
GO:0042594 IEP:RGDPresponse to starvation
KEGG Pathway Links
KEGG Pathway IDDescription
ko00650Butanoate metabolism
rno00650Butanoate metabolism
M00036Leucine degradation, leucine => acetoacetate + acetyl-CoA
rno01100Metabolic pathways
ko04146Peroxisome
rno04146Peroxisome
ko00072Synthesis and degradation of ketone bodies
rno00072Synthesis and degradation of ketone bodies
ko00280Valine, leucine and isoleucine degradation
rno00280Valine, leucine and isoleucine degradation
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953366Ketone body metabolism
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5953365Synthesis of Ketone Bodies