LMPD Database

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LMP012763

Record overview

LMPD IDLMP012763
Gene ID81681
SpeciesMacaca mulata (Rhesus monkey)
Gene Namelanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Gene SymbolLss
Alternate nameslanosterol synthase; OSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase; 2,3-oxidosqualene: lanosterol cyclase;
Chromosome20
Map Location20p12
EC Number5.4.99.7
Summaryenzyme that catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Lss

Proteins

lanosterol synthase
Refseq ID:NP_112311
Protein GI:13591981
UniProt ID:P48450
mRNA ID:NM_031049
Length:733
RefSeq Status:
MTEGTCLRRRGGPYKTEPATDLTRWRLHNELGRQRWTYYQAEEDPGREQTGLEAHSLGLDTTSYFKNLPKAQTAHEGALNGVTFYAKLQAEDGHWAGDYG
GPLFLLPGLLITCHIAHIPLPAGYREEMVRYLRSVQLPNGGWGLHIEDKSTVFGTALSYVSLRILGIGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAV
LNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGL
LNLYERFHSTSLRKWAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQTWDTSFAVQALLEA
GAHRRPEFLPCLQKAHEFLRLSQVPDNNPDYQKYYRHMHKGGFPFSTLDCGWIVADCTAEALKAVLLLQERCPSITEHVPRERLYDAVAVLLSMRNSDGG
FATYETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFREYFPDHRATEIRETLNQGLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACM
GHIYQNRTACAEVAQACHFLLSRQMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGLMAVRHPDISAQERGIRCLLGKQLPNGDWPQENISGVFNKS
CAISYTNYRNIFPIWALGRFSSLYPDNTLAGHI