LMPD Database

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LMP013208

Record overview

LMPD IDLMP013208
Gene ID301517
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecytochrome P450, family 27, subfamily a, polypeptide 1
Gene SymbolCyp27a1
SynonymsCyp27; P450C27;
Alternate namessterol 26-hydroxylase, mitochondrial; cytochrome P450 27; sterol 27-hydroxylase; cytochrome P-450c27/25; vitamin D(3) 25-hydroxylase; 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase;
Chromosome9
Map Location9q33
EC Number1.14.13.15
Summarymitochondrial enzyme with both vitamin D3 25-hydroxylase and cholesterol 26-hydroxylase activities [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Cyp27a1

Proteins

sterol 26-hydroxylase, mitochondrial
Refseq ID:NP_849178
Protein GI:139949139
UniProt ID:P17178
mRNA ID:NM_178847
Length:533
RefSeq Status:
MAVLSRMRLRWALLDTRVMGHGLCPQGARAKAAIPAALRDHESTEGPGTGQDRPRLRSLAELPGPGTLRFLFQLFLRGYVLHLHELQALNKAKYGPMWTT
TFGTRTNVNLASAPLLEQVMRQEGKYPIRDSMEQWKEHRDHKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAALYTDALNEVISDFIARLDQVRTESAS
GDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTATFIRSVGLMFKNSVYVTFLPKWSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQ
AAGPDGVQVSGYLHFLLTKELLSPQETVGTFPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFGKVPQNKDFAHMPLLKAVIKETLRLYP
VVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQKY
EVVLSPGMGEVKSVSRIVLVPSKKVSLRFLQRQ
 

transit_peptide: 1..32
experiment: experimental evidence, no additional details recorded
note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (P17178.1)
calculated_mol_wt: 3566
peptide sequence: 
MAVLSRMRLRWALLDTRVMGHGLCPQGARAKA

mat_peptide: 33..533
product: Sterol 26-hydroxylase, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P17178.1)
calculated_mol_wt: 57185
peptide sequence: 
AIPAALRDHESTEGPGTGQDRPRLRSLAELPGPGTLRFLFQLFLRGYVLHLHELQALNKAKYGPMWTTTFGTRTNVNLASAPLLEQVMRQEGKYPIRDSM
EQWKEHRDHKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAALYTDALNEVISDFIARLDQVRTESASGDQVPDVAHLLYHLALEAICYILFEKRVGCLE
PSIPEDTATFIRSVGLMFKNSVYVTFLPKWSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGPDGVQVSGYLHFLLTKELLSPQETVGTFP
ELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFGKVPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHY
VVSRDPSVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQKYEVVLSPGMGEVKSVSRIVLVPSKKVSLRFLQR
Q