Time course results for Bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin: Sterols

Legend: graph_icon: View data/graphs for replicates   graph_icon: View time course graphs for averages of biological replicates

25-OHC = 25-hydroxy-cholesterol(normal media)/Control; 25-OHC* = 25-hydroxy-cholesterol(lipid-depleted media + compactin)/Control;
RepressionInduction
Measurements were in pmol/sample

Details
GraphLM_ID Name25-OHC
25-OHC*
30 min		25-OHC
25-OHC*
1 hr		25-OHC
25-OHC*
2 hr		25-OHC
25-OHC*
4 hr		25-OHC
25-OHC*
8 hr		25-OHC
25-OHC*
12 hr		25-OHC
25-OHC*
24 hr
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03010040   1,25-dihydroxy Vitamin D2
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03020660   1,25-dihydroxy Vitamin D3
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010176   14-Demethyllanosterol
2.66     
1.31     
1.38     
0.484     
1.37     
1.12     
0.709     
0.898     
0.569     
0.89     
1.16     
1.29     
0.7     
1.69     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010267   15α-hydroxycholestene
2.12     
0.981     
1.2     
1.8     
1.62     
1.11     
1.24     
1.94     
1.21     
1.54     
1.62     
1.48     
2.77     
0.734     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010268   15β-hydroxycholestene
1.62     
0.637     
1.35     
1.26     
1.94     
1.18     
1.14     
1.05     
1.52     
1.28     
0.791     
0.786     
0.911     
1.89     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010270   15-ketocholestane
2.09     
1.41     
1.23     
1.02     
1.19     
1.78     
1.78     
1.81     
0.917     
0.833     
1.37     
1.2     
1.06     
1.37     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010269   15-ketocholestene
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03020231   1α-hydroxy Vitamin D3
1.86     
0.879     
1.05     
1.03     
1.36     
1.18     
0.884     
0.977     
0.784     
1.07     
1.5     
1.3     
1.03     
1.26     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010086   22R-hydroxy-cholesterol
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010012   24,25-epoxy-cholesterol
1.7     
1.17     
0.932     
1.28     
1.17     
1.25     
0.745     
1.06     
0.743     
1.18     
1.03     
1.22     
0.768     
1.28     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010087   24-dihydro Lanosterol
2.11     
0.985     
1.03     
0.995     
1.1     
0.927     
0.697     
0.623     
0.457     
0.82     
0.775     
1.45     
0.403     
1.03     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010133   24-oxocholesterol
1.95     
0.908     
1.27     
1.03     
1.61     
0.974     
0.884     
0.845     
0.924     
0.927     
1.47     
1.13     
1.04     
1.07     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010019   24S-hydroxy-cholesterol
6.32     
1.24     
1.22     
1.1     
1.5     
1.52     
0.994     
1.65     
0.798     
1.07     
1.17     
1.75     
1.55     
2.35     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010018   25-hydroxy-cholesterol
92.4     
54.4     
84.3     
127     
86.7     
121     
82.7     
121     
71.3     
119     
92.7     
145     
66.5     
134     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03010030   25-hydroxy Vitamin D2
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03020246   25-hydroxy Vitamin D3
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010057   27-hydroxy-cholesterol
1.58     
1.03     
1.38     
1.4     
2.14     
1.45     
2.09     
2.41     
2.78     
4.32     
4.92     
8.08     
3.45     
9.92     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST04030178   3,7,27-trihydroxy cholesterol
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010052   3β,5α,6β-trihydroxycholestanol
2.75     
1.23     
1.22     
0.937     
0.971     
1.78     
0.822     
1.57     
2.11     
1.62     
1.83     
1.14     
1.25     
0.958     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010271   3oxo,7α-hydroxycholesterol
2.73     
1.6     
0.633     
2.29     
1.78     
0.889     
0.681     
1.69     
1.25     
1     
2     
1.23     
0.714     
1.06     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010014   4β-hydroxy-cholesterol
1.76     
1.03     
1.11     
1.12     
1.13     
1.05     
0.874     
0.838     
0.806     
1     
1.13     
1.1     
0.866     
1.17     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010135   6α-hydroxy-cholestanol
1.88     
1.07     
1     
1.11     
1.37     
1.06     
0.816     
1.03     
0.787     
0.912     
0.945     
0.967     
0.75     
1.43     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010013   7α-hydroxy-cholesterol
1.85     
0.85     
1.05     
1.12     
1.78     
2.06     
1.65     
1.17     
1.3     
1.21     
1.66     
1.68     
1.13     
1.39     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010069   7-Dehydrocholesterol
1.36     
0.72     
0.965     
1.27     
0.844     
1.05     
0.436     
0.838     
0.323     
0.794     
0.473     
1.12     
0.405     
1.12     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010272   7-oxo-cholestenone
2.39     
1.04     
0.936     
1.64     
1.35     
0.847     
1.26     
1.15     
0.981     
1.27     
1.2     
1.05     
1.03     
1.21     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010049   7-oxo-cholesterol
1.68     
0.968     
1.11     
1.2     
1.2     
0.91     
0.87     
0.763     
0.782     
0.876     
1.11     
0.811     
0.826     
1.02     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01030097   Campesterol
2.06     
1.12     
0.963     
1.3     
1.26     
0.952     
0.76     
0.814     
0.743     
0.991     
0.895     
1.03     
0.566     
1.16     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010077   Cholestanol
2.14     
1.1     
1.05     
1.26     
1.29     
1     
0.712     
0.741     
0.625     
0.93     
0.935     
0.854     
0.591     
0.989     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010015   Cholestenone
1.3     
0.579     
1.08     
1.58     
1.38     
1.12     
0.923     
0.87     
0.706     
0.98     
1.31     
1.45     
0.97     
2.03     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010001   Cholesterol
1.92     
1.1     
1.24     
1.23     
1.33     
1.02     
0.75     
0.901     
0.674     
0.971     
1.18     
1.47     
0.831     
1.23     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01031023   Dehydroergosterol
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010016   Desmosterol
1.84     
0.936     
1.15     
1.24     
1.31     
1.08     
0.773     
0.816     
0.673     
1.02     
1.02     
1.21     
0.761     
1.83     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010017   Lanosterol
2.18     
1.14     
0.878     
1.61     
0.643     
1.35     
0.341     
0.94     
0.295     
3.53     
0.41     
1.36     
0.242     
2.45     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01040129   Sitosterol
2.19     
0.947     
1.15     
1.02     
1.36     
1.04     
0.765     
0.957     
0.634     
0.971     
1.28     
1.24     
0.812     
1.44     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01040124   Stigmasterol
1.46     
1.61     
1.93     
1.18     
1.6     
1.96     
0.709     
1.07     
0.839     
0.732     
1.86     
1.13     
1.14     
2.01     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03010001   Vitamin D2
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST03020001   Vitamin D3
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
-     
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMST01010066   Zymosterol
1.02     
0.064     
1.01     
0.428     
0.787     
0.778     
0.279     
0.751     
0.203     
0.493     
0.219     
-     
0.078     
0.783     

Treatment/Control ratio:<=0.1<=0.2<=0.25<=0.33<=0.5<=0.67 --- >=1.5>=2>=3>=4>=5>=10 No value
Color: