Lipidomics Studies on Bone Marrow-derived Macrophages Treated with ATP / Kdo2-Lipid A
Sterols
|
Induction
| Details | Graph | LM_ID | Name | Kdo+ATP Kdo ATP 15 min |
Kdo+ATP Kdo ATP 30 min |
Kdo+ATP Kdo ATP 1 hr |
Kdo+ATP Kdo ATP 2 hrs |
Kdo+ATP Kdo ATP 4 hrs |
Kdo+ATP Kdo ATP 8 hrs |
Kdo+ATP Kdo ATP 20 hrs |
|---|---|---|---|---|---|---|---|---|---|---|
 |
Legend:
 :Ctrl
 :Kdo2-lipid A
 :ATP
 :ATP+Kdo2-lipid A
| LMST01010012 | 24,25-epoxy-cholesterol | 1.26
1.09
0.992
| 1.23
1.16
1.06
| 1.21
1.19
1.05
| 1.08
1.1
0.983
| 1.08
1.27
0.963
| 1.23
1.12
1.02
| 1.11
1.3
1.08
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010018 | 25-hydroxy-cholesterol | 2.32
2.06
1.05
| 2.66
2.59
0.983
| 2.25
2.49
1.04
| 2.17
3.05
0.991
| 3.04
3.46
1.61
| 5
3.11
5.31
| 4.24
3.71
5.66
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010057 | 27-hydroxy-cholesterol | -
-
-
| -
-
-
| -
-
-
| 0.722
-
0.609
| -
-
-
| -
0.933
-
| 0.846
1.08
-
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010014 | 4beta-hydroxy-cholesterol | 1.34
0.913
1.01
| 2.21
1.14
1.08
| 1.57
1.12
1.71
| 1.02
1.18
1.22
| 1.21
1.01
1.03
| 1.14
0.889
0.945
| 1.49
1.34
1.19
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010013 | 7alpha-hydroxy-cholesterol | 1.3
0.679
0.961
| 9.14
1.36
2.39
| 3.07
1.08
7.56
| 2.61
1.84
3.57
| 3.1
1.26
2.63
| 1.29
0.493
1.11
| 3
1.34
2.08
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010069 | 7-Dehydrocholesterol | 1.68
1.64
1.04
| 0.77
1.18
1.14
| 1.46
1.25
1.1
| 1.17
1.04
1.1
| 0.887
0.895
0.95
| 0.807
0.721
0.966
| 1.38
1.25
0.739
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010049 | 7-oxo-cholesterol | 1.18
0.784
0.841
| 3.76
1.22
1.24
| 1.75
1.16
2.94
| 1.41
1.46
1.45
| 1.61
1.16
1.41
| 1.4
0.86
1.27
| 2.24
1.54
2.04
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010015 | Cholestenone | 0.807
1.02
0.796
| 2.98
1.17
1.54
| 1.92
1.59
2.44
| 1.15
0.884
1.35
| 1.46
0.885
1.21
| 1.13
0.899
1.03
| 2.43
1.33
1.68
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010001 | Cholesterol | 1.28
0.991
1.06
| 1.39
1.22
1.08
| 1.31
1.19
1.08
| 1.09
1.12
1.01
| 1.13
1.21
1.02
| 1.16
1.2
1
| 1.27
1.42
1.12
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010016 | Desmosterol | 1.37
1.11
0.991
| 1.45
1.3
1.04
| 1.37
1.4
1.06
| 1.23
1.26
1.11
| 1.01
1.17
0.836
| 1.14
1.09
0.864
| 1.09
1.67
0.98
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| LMST01010017 | Lanosterol | 1.95
2
0.855
| 3.51
2.26
1.19
| 3.86
2.69
1.24
| 4.47
3.5
1.3
| 3.64
7.1
1.12
| 5.54
12.3
4.47
| 16.3
21.5
16.3
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | DNA | 1.01
1.06
1.03
| 0.982
0.83
0.964
| 0.804
1.04
0.965
| 0.673
0.766
0.717
| 0.547
1.09
0.812
| 0.738
0.784
0.876
| 0.648
1.07
0.916
|