Pathways

LIPID MAPS WikiPathways

LIPID MAPS has contributed a set of 10 pathways to the WikiPathways project. Pathways include metabolism of

  • cholesterol
  • eicosanoids
  • glycerolipids
  • omega fatty acids
  • sphingolipids
Browse Pathways

References

  • Slenter DN, Kutmon M, Hanspers K, Riutta A, Windsor J, Nunes N, Mélius J, Cirillo E, Coort SL, Digles D, Ehrhart F, Giesbertz P, Kalafati M, Martens M, Miller R, Nishida K, Rieswijk L, Waagmeester A, Eijssen LMT, Evelo CT, Pico AR, Willighagen EL.
    WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research Nucleic Acids Research, (2017)
    DOI: 10.1093/nar/gkx1064  PMCID: PMC5753270

LIPID MAPS WikiPathways

Lipid-related pathways, or portions of pathways are displayed in tabular format with lipid structures and related information organized in columns. Pathways may also be viewed in an enzymatic reaction format, where substrate and product are displayed in separate rows, with an intervening row showing the gene information for the enzyme catalyzing that step.

Pathway table

LIPID MAPS WikiPathways

SphinGOMAP© is a a web-based biosynthetic pathway map of sphingolipids and glycosphingolipids developed during the 2003-2013 grant period by the LIPID MAPS Consortium's Sphingolipid Core Lab, directed by professor Al Merrill.

SphinGOMAP© includes over four hundred sphingolipids and glycosphingolipids arranged according to their biosynthetic steps, or in the cases where all of the intermediates have not yet been identified, in hypothetical pathways.

The current Lipidomics Gateway implementation of SphinGOMAP© incorporates links to lipids found in the LIPID MAPS Structure Database (LMSD).

Please visit Dr Merrill's SphinGOMAP© website to learn more.

sphingomap thumbnail

References

  • Slenter DN, Kutmon M, Hanspers K, Riutta A, Windsor J, Nunes N, Mélius J, Cirillo E, Coort SL, Digles D, Ehrhart F, Giesbertz P, Kalafati M, Martens M, Miller R, Nishida K, Rieswijk L, Waagmeester A, Eijssen LMT, Evelo CT, Pico AR, Willighagen EL.
    WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research Nucleic Acids Research, (2017)
    DOI: 10.1093/nar/gkx1064  PMCID: PMC5753270

These lipid signaling pathway maps are provided courtesy of Cayman Chemical Company and include:
  • Arachidonic Acid Cascade
    — the three main branches of the Arachidonic Acid Cascade (cyclooxygenase, lipoxygenase, and CYP450 pathways) which produce many of the lipids that serve as second messengers in cellular signaling
  • Lysophospholipid Signaling
    — synthesis and G-protein signaling cascades for lysophospholipids LPA, LysoPS, LPI, and S1P

View larger image: 9150 pixels x 6150 pixels (21M)

Learn more and/or request a physical copy from Cayman Chemical Company.

Arachidonic_Acid_Cascade

View larger image: 9000 pixels x 6000 pixels (15M)

Learn more and/or request a physical copy from Cayman Chemical Company.

Lysophospholipid_Signaling