Lipidomics update - April, 2017

The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike.

LIPID MAPS® highlights

LIPID MAPS Classification updates: The LIPID MAPS Classification system, comprised of eight lipid categories -- Fatty Acyls, Glycerolipids, Glycerophospholipids, Sphingolipids, Sterol Lipids, Prenol Lipids, Saccharolipids, and Polyketides, each with its own subclassification hierarchy -- now includes a new Polyketides class, "Phenolic lipids", with 5 subclasses; In addition, there are now 3 new subclasses of Octadecanoids; 3 new subclasses of Eicosanoids; and 7 new subclasses of Docosanoids.

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Lipid of the month

15R-hydroxy-12S,14R-dioxolane-EET

15R-hydroxy-12S,14R-dioxolane-EET (15R-hydroxy-12S,14R-dioxolane-5Z,8Z,10E-eicosatrienoic acid) is an eicosanoid containing a 1,2-dioxolane (cyclic peroxide) group. Dioxolanes of this type have been generated from enantiomers of 14,15-EET by two mammalian LOX enzymes, 15-LOX-1 and platelet-type 12-LOX. This type of transformation could occur naturally with the co-occurrence of LOX and cytochrome P450 or peroxygenase enzymes.

Research library

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