Lipidomics update - April, 2018
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike.
LIPID MAPS® highlights
The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids and includes representative examples from each category of the LIPID MAPS Lipid Classification System. LMSD is the largest public lipid-only database in the world, containing over 40,000 unique lipid structures. Entries include lipids from human, mouse, plants, bacteria, fungi, algae and marine organisms, and computationally generated structures (annotated as such).
Lipid of the month
2-oleoyl-glycerol
2-oleoyl-glycerol (Systematic Name:2-(9Z-octadecenoyl)-sn-glycerol) is a monoacylglycerol that is found in biological tissues. Monoacylglycerols or monoglycerides are a class of glycerolipids which are composed of a molecule of glycerol linked to a fatty acid via an ester bond. They are typically present at low levels in cell extracts but are intermediates in the degradation of triacylglycerols and diacylglycerols (lipolysis). 2-oleoyl-glycerol was found to be an endogenous ligand to the G protein-coupled receptor GPR119 and has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.
Events calendar
3rd International Conference on Lipid Science & Technology
Dec 11-12, 2017
Rome, ItalyBioinformatics 2018: 9th International Conference on Bioinformatics Models, Methods, and Algorithms
January 19-21, 2018
Funchal, Madeira, Portugal
Research library
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The discovery and early structural studies of arachidonic acid.
J Lipid Res
2016 Jul;57(7):1126-32. doi: 10.1194/jlr.R068072. Epub 2016 May 3.
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Using lipidomics analysis to determine signalling and metabolic changes in cells
J Lipid Res
Curr Opin Biotechnol. 2017 Feb;43:96-103. doi: 10.1016/j.copbio.2016.10.003. Epub 2016 Nov 4.