Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Averages of biological replicates - (GP) Cardiolipins

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
DetailsTime course graph
(ave of biol. reps) 		LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs
Units
. . . .

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(64:1) -
1.19
-
1.36		 0.983
0.877
1.03
0.85		 0.723
0.84
0.937
0.92		 0.94
0.997
0.573
0.62		 0.907
0.97
1.08
1.01		 0.93
0.56
1.38
1.02		 1.03
0.773
1.13
0.713		 0.657
0.667
1.58
1.16		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(64:2) -
1.2
-
1.28		 1.38
1.48
1.31
1.5		 1.02
1.83
1.25
1.47		 1.22
1.14
0.55
0.46		 0.9
0.725
0.91
0.68		 0.775
1.08
1.43
0.745		 1.04
0.905
1.17
0.855		 0.755
0.94
1.38
0.84		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(64:3) -
4.68
-
3.24		 4.55
4.32
4.52
3.33		 3.48
3.51
3.96
4.16		 5.45
5.48
3.21
3.01		 4.12
4.6
4.02
3.44		 3.52
3.12
4.49
3.28		 3.19
3.64
2.41
2.23		 2
2.86
4.3
3.53		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(64:4) -
2.7
-
2.25		 2.79
2.85
2.88
2.52		 2.16
2.71
2.56
2.92		 3
3.17
2.06
2.05		 2.76
2.89
2.49
2.24		 2.02
1.83
2.79
2.17		 1.87
2.32
1.62
1.71		 1.25
1.73
2.18
2		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:1) -
0.343
-
0.383		 0.44
0.22
0.597
0.26		 0.3
0.297
0.453
0.41		 0.55
0.49
0.327
0.565		 0.583
0.463
0.81
0.68		 0.497
0.27
1.48
0.67		 0.73
0.37
1.15
0.447		 0.633
0.373
2.02
0.803		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:2) -
2.11
-
2.17		 1.89
1.97
2.15
1.62		 1.46
1.51
2.08
2.2		 2.17
2.34
1.59
1.73		 2.06
1.9
2.62
2.24		 2.14
1.46
4.04
2.62		 2.18
1.99
2.56
1.83		 1.4
1.39
5.51
3.26		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:3) -
5.21
-
4.37		 4.98
4.92
4.94
3.96		 3.78
3.92
4.57
4.8		 6.05
6.91
4.32
4.78		 5.74
5.74
6.06
5.08		 4.94
4.52
7.13
5.43		 4.39
5.02
3.96
3.85		 2.82
3.84
8.88
6.38		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:4) -
9.62
-
7.39		 9.4
9.09
7.8
7.01		 7.33
8.06
8.21
9.13		 10.5
12.1
8.92
9.02		 10.9
10.9
9.75
8.89		 8.11
8.93
9.7
8.46		 6.78
7.77
5.23
5.83		 4.48
5.35
9.38
7.18		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:5) -
2.63
-
3.04		 2.94
2.53
2.23
2.44		 1.91
2.43
2.45
2.89		 2.82
3.25
2.63
2.96		 3.33
2.96
3.02
2.64		 2.02
2.46
2.51
2.48		 1.74
1.91
1.42
1.6		 1.25
1.44
2.12
1.86		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(66:6) -
3.23
-
3		 3.18
2.56
2.94
2.73		 2.66
2.95
2.98
3.27		 3.16
3.75
2.23
2.33		 3.36
3.18
3.47
3.01		 2.62
2.47
4.02
3.05		 2.66
2.8
2.24
2.09		 1.85
2.42
3.42
2.82		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:1) -
0.867
-
0.73		 0.663
0.483
0.817
0.95		 0.707
0.887
0.77
0.583		 0.547
0.593
0.353
0.463		 0.63
0.753
0.73
0.527		 0.483
0.56
1.04
0.915		 0.597
0.387
0.74
0.77		 0.837
0.587
1.53
0.74		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:2) -
3.53
-
4.39		 2.92
3.2
4.45
3.43		 2.35
2.18
3.89
4.1		 4.03
4.46
3.87
4.35		 3.94
3.42
6.07
4.85		 4.51
2.7
9.2
5.91		 4.64
3.65
5.83
3.85		 2.78
2.42
12.7
6.21		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:3) -
7.98
-
7.3		 7.27
6.42
6.62
6.49		 4.79
5.56
6.75
8.26		 8.08
9.11
8.23
8.16		 8.69
8.55
9.31
8.57		 7.12
7.05
11
9.31		 6.57
6.54
7.15
7.14		 4.62
4.76
14.2
9.32		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:4) -
22.6
-
18		 22.1
20.5
17.1
17.1		 16.6
19.5
19.9
23		 25.3
27.7
24.2
27.4		 28.2
27.1
25.4
23.8		 19.3
23.8
22.6
23.1		 17.6
18.6
14.1
16.8		 13.5
14.2
20.5
17.3		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:5) -
13.1
-
10.4		 12.2
11.1
9.54
9.38		 8.45
10.3
12
13.8		 13.8
15.5
14.6
16.9		 15.8
15.5
15.4
14.3		 10.2
14
12.2
13.1		 8.98
9.38
7.74
9.86		 6.42
6.83
9.37
8.93		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(68:6) -
8.82
-
7.42		 8.12
7.96
8.18
7.1		 6.74
6.96
8.4
9.12		 10.3
11.2
8.21
8.33		 10.3
9.79
10.2
10		 7.38
8.28
10.9
9.33		 6.39
7.45
5.74
6.19		 4.4
5.64
8.5
7.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(70:2) -
1.33
-
1.88		 1.43
1.38
1.58
1.29		 1.12
1.19
1.24
1.58		 1.41
1.55
1.22
1.82		 1.51
1.82
1.87
1.9		 1.37
1.01
2.48
2.37		 1.28
1.19
1.68
1.42		 0.953
0.767
3.11
2.43		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(70:3) -
7.79
-
7.6		 5.79
5.64
5.36
5.82		 3.88
4.53
6.8
8.19		 7.59
8.65
10
10.2		 8.04
7.81
9.27
8.94		 5.61
6.77
8.3
10.2		 5.31
5.04
6.28
6.93		 3.88
3.87
9.88
7.25		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(70:4) -
27.2
-
22		 24.5
23.9
21
20		 19.9
22.5
23.8
27		 29
30.9
27.5
36.3		 32.8
32.1
31.7
30		 25.3
33.8
27.1
28.9		 24.1
24.4
21.6
26.1		 21.5
21.9
26.9
24.3		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(70:5) -
21
-
16.2		 17.4
17.9
15.2
14.7		 13.2
15.5
19.4
22.5		 21.9
23.3
24.2
34.9		 24.6
24.5
24.8
24.3		 15
28.3
18
22.9		 13.9
14.4
14.5
15.5		 12.7
12.9
15.9
15.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(70:6) -
14
-
10.4		 10.5
11.3
10.7
9.64		 9.2
9.87
11.8
13.5		 14.4
15.7
13.2
20.3		 15.8
16.3
17.4
16.8		 10.3
11.8
13.4
13.2		 9.46
10
9.56
11.6		 7.66
8.11
9.95
10.6		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:2) -
3.46
-
2.74		 4.68
3.38
2.68
3.26		 2.47
3.66
4.36
5.76		 3.92
3.98
4.77
8.7		 3.82
3.91
3.82
3.76		 3.13
4.24
3.15
3.85		 3.56
3.07
3.12
3.52		 3.34
3.38
3.58
3.36		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:3) -
15.6
-
12.1		 12.1
12.3
10.7
10.2		 9.76
10.8
12.3
14.4		 15.2
16.2
15.6
23.5		 16.2
15.8
15.8
15.7		 12.2
14.6
11.9
14.7		 12.2
12.8
11.6
13.1		 12.2
13.1
13.4
13.3		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:4) -
20.8
-
17		 16.1
16.6
16.4
15.2		 13.9
14.9
17.6
20		 20.8
22
20.7
36.3		 21.7
22.1
24.2
23.1		 17.6
22.3
19.9
21.3		 17.6
18.1
18.6
21		 17
17.7
20.6
21.2		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:5) -
18.9
-
16		 13.9
15
15.3
14.1		 12.7
13
15.9
17.6		 19
20.4
18.3
34.6		 19.2
19.8
23.8
22.2		 15.3
21.3
19.7
19.3		 15
15.4
16.8
18.6		 13.5
14
17.6
18.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:6) -
8.93
-
7.29		 6.44
7.13
7.08
6.53		 5.97
6.14
7.28
7.49		 9.21
9.7
8.27
17.2		 8.6
9.54
11.1
10.2		 6.94
10.4
9.02
8.24		 6.73
7
7.38
8.19		 5.93
5.97
7.69
8.25		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(72:7) -
5.09
-
4.43		 3.78
4.06
3.96
3.71		 3.55
3.42
3.89
4.11		 5.39
5.55
4.44
8.94		 4.63
5.42
5.96
5.37		 4.07
5.97
4.81
4.29		 3.92
4.07
3.98
4.33		 3.34
3.43
4.2
4.21		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:4) -
0.835
-
2.86		 1.88
1.3
1.72
1.77		 1.94
2.22
1.82
2.02		 0.955
1.03
1.22
2.08		 1.3
1.38
1.18
1.19		 1.26
1.95
0.855
1.21		 1.28
1.56
1.23
1.36		 1.75
1.57
1.04
1.05		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:5) -
1.93
-
1.33		 1.32
1.09
1.15
1.41		 1.13
1.21
1.25
1.56		 1.84
1.77
1.89
2.64		 1.57
1.65
1.71
1.86		 1.14
2.29
1.18
1.41		 1.23
1.29
1.26
1.28		 1.37
1.55
1.5
1.38		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:6) -
4.46
-
3.78		 3.62
3.85
3.51
3.25		 3.25
3.36
3.58
3.87		 4.74
4.94
4.01
8.71		 4.34
5.07
5.48
4.73		 4.28
6.27
4.61
4.22		 4.27
4.48
4.34
4.58		 4.49
4.5
4.91
5.07		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:7) -
5.59
-
5.16		 4.48
4.71
4.78
4.63		 4.12
4.3
4.63
4.89		 6.07
6.06
5.27
11.8		 5.29
5.91
7.3
5.99		 5.08
8.61
6.39
5.47		 5.24
5.24
5.51
6.12		 4.89
5.18
6.19
6.54		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:8) -
3.62
-
3.32		 2.92
3.39
3.09
2.79		 2.85
2.8
3.44
3.26		 4.2
4.21
3.66
8.46		 3.78
4.19
5.33
4.22		 3.73
6.38
4.46
4		 3.63
3.84
4.2
4.38		 3.25
3.33
4.43
4.76		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
- CL(74:9) -
4.59
-
4.84		 3.82
4.28
4.16
3.99		 3.54
3.95
3.75
3.86		 4.62
4.39
3.82
7.33		 4.15
4.4
5.44
4.08		 3.78
6.26
4.48
4.15		 3.94
3.76
3.74
4.19		 3.96
3.64
4.2
4.13		 pmol/sample