Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Averages of biological replicates - (FA) Fatty acids [cells]

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
DetailsTime course graph
(ave of biol. reps) 		LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs
Units
. . . .

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030283 10Z-heptadecenoic acid -
6.27
-
7.5		 4.54
6.87
3.72
5.11		 5.98
5.2
5.7
6.24		 5.49
4.46
4.29
5.63		 6.07
5.16
4.81
5.51		 5.53
5.51
5.31
7.8		 6.36
4.66
4.89
6.79		 6.38
4.86
5.27
6.29		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030159 11,14,17-eicosatrienoic acid -
12.9
-
11.1		 12.7
12
11.9
9.88		 11.8
12.7
13.7
13		 13.1
12.7
9.74
12.4		 12.4
15.3
11.7
11.4		 16.1
16.4
13.7
14.5		 14.8
16.8
15.4
23.4		 17.9
25.9
18.4
22.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030130 11,14-eicosadienoic acid -
5.87
-
5.04		 6.14
6.07
3.68
4.69		 7.18
6.01
4.63
4.55		 4.56
6.13
3.71
3.78		 6.22
4.52
4.18
4.09		 6.34
4.3
5.23
4.88		 5.77
5.16
5.47
6.84		 7.08
6.56
4.01
5.36		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030408 13,16,19-docosatrienoic acid -
-
-
0.61		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 1.31
0.21
-
-		 -
0.33
0.28
-		 0.35
0.65
1.63
0.56		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030132 13,16-docosadienoic acid -
3.86
-
2.44		 3.06
3.81
3.02
4.14		 3.43
2.59
2.28
2.2		 3.77
2.12
1.83
1.95		 3.49
2.77
3.46
2.69		 -
4.59
3.82
4.05		 2.9
3.19
3.32
4.16		 3.39
3.57
3.76
4.12		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030759 5,8,11,14,17-eicosapentaenoic acid -
7.76
-
7.58		 6.2
17.2
8.13
8.82		 6.28
14.5
20.1
8.91		 12.5
5.99
9.86
5.93		 12.5
13.4
13.5
6.08		 8.85
7.43
13.6
13.9		 9.45
9.39
6.99
8.45		 9.85
6.51
7.37
9.13		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030157 5,8,11-eicosatrienoic acid -
0.3
-
0.38		 -
0.485
-
0.65		 0.49
0.2
0.675
-		 0.23
0.845
0.73
1.04		 1.32
0.53
1.34
0.35		 1.91
1.77
0.19
1.4		 2.09
0.1
0.3
0.83		 1.2
2.78
0.54
1.34		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030184 7,10,13,16,19-docosapentaenoic acid -
37.8
-
34.4		 30.7
33.2
37.4
35.8		 29.7
30.8
34.8
38		 30.9
27.8
31.3
37.8		 26.8
31.3
34.1
41		 32.5
29.1
34.9
39.8		 37.5
33.8
35.4
44.9		 39
38.3
35
45.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030178 7Z,10Z,13Z,16Z-docosatetraenoic acid -
17.7
-
17.4		 15.8
14.8
17.5
17.8		 12.7
14.3
16.6
18.4		 15.2
12.4
14
17.6		 12.8
14.2
16.1
19.2		 16.9
14.5
16.7
19.4		 16.3
14.1
15.8
21.2		 18.3
18.4
18.2
20.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030056 9Z-palmitoleic acid -
37.3
-
24.1		 25.3
25.5
35.8
25.5		 32.2
35.7
24.2
31.2		 32.4
35.1
20.3
26.7		 34.8
33.1
21.6
24.6		 37.9
32.4
29.4
30.2		 45.7
46.2
27.2
36.4		 50.6
43.9
38.7
40.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030152 alpha-linolenic acid -
0.48
-
0.635		 0.39
0.48
0.59
0.57		 0.83
0.37
0.515
0.4		 0.54
0.315
0.37
0.54		 0.23
0.395
0.515
0.99		 -
0.75
0.57
0.83		 0.395
1.45
0.445
0.715		 1.39
1.67
0.43
1.31		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010020 Arachidic acid -
10.2
-
3.34		 1.95
4.56
3.51
0.96		 0.34
3.11
6.49
-		 0.505
3.2
-
2.89		 2.77
2.29
2.96
0.45		 6.59
3.6
2.95
4.11		 4.64
2.28
2.86
-		 5.68
8.78
5.13
17.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030001 Arachidonic acid -
92.9
-
97.3		 87.1
78.8
93.8
101		 77.4
91.6
104
102		 68.2
80.4
84.7
103		 80.5
88.8
104
104		 87.9
95.5
127
130		 101
100
109
161		 109
120
117
145		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010022 Behenic acid -
3.75
-
12.4		 2.62
3.23
4.68
4.19		 3.39
6
4.08
11.7		 5.14
3.5
10.9
9.76		 6.06
4.8
5.39
3.58		 7.83
7.08
4.16
7.54		 7.63
4.9
6.56
4.75		 7.09
4.82
4.49
6.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030158 bishomo-gamma-linolenic acid -
12
-
12.4		 10.8
10.5
10.9
11.9		 10.1
10.8
9.68
12.9		 10.3
11.1
9.97
12.8		 10.2
11
12.1
13		 12.1
12.3
15.1
16.3		 14.6
12.5
15.4
21.2		 14.5
17.4
13.9
16.6		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010026 Cerotic acid -
1.43
-
1.34		 2.03
2.43
2.9
2.63		 2.99
3.55
2.08
5.84		 1.7
1.06
3.99
2.58		 2.54
4.22
2.69
1.77		 2.03
2.1
1.59
1.8		 1.37
1.42
3.71
1.2		 3.71
2.1
1.72
2.59		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030089 cis-erucic acid -
6.51
-
3.17		 5.05
5.51
2.81
3.61		 5.64
6.29
5.38
4.41		 7.02
5.16
3.41
4.27		 5.97
4.09
3.72
3.53		 8.17
5.56
4.58
3.36		 8.96
4.59
4.19
5.31		 12.5
10.2
6.6
5.97		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030092 cis-selacholeic acid -
1.15
-
2.6		 2.15
1.99
1.54
2.63		 1.6
1.35
2.15
2.25		 1.79
1.46
1.01
1.6		 2.39
1.47
1.67
1.36		 2.41
1.34
1.44
2.04		 2.06
1.69
1.64
1.55		 2.61
1.35
2.56
1.33		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030185 DHA -
38.6
-
35.8		 32.8
33.5
39.7
35.5		 24.6
31.2
38.7
39.6		 31.3
26.9
30.7
37.4		 24.8
27.3
33.8
42.7		 33.3
32.2
35.7
41.4		 37
29.2
35.8
51.7		 39.8
35.6
37.3
46.2		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030141 gamma-linolenic acid -
0.805
-
1.04		 0.93
1.31
0.815
1.16		 0.8
0.73
0.885
0.845		 0.865
0.925
0.605
0.7		 0.86
0.905
1.13
0.91		 2.18
0.5
1.35
1.33		 1.6
1.26
0.585
1.46		 0.64
2.14
1.23
1.27		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010012 Lauric acid -
54.1
-
50		 109
74.1
56
73.9		 90.4
66.6
57.2
101		 93.4
108
106
92.9		 96.5
71.8
63.9
48.7		 54
67.4
91.6
73.6		 74.4
64.1
57.6
47.9		 51.4
55.1
49.8
76.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010024 Lignoceric acid -
16.6
-
20.1		 6.22
9.78
11.8
6.68		 13
8.37
9.67
13.8		 12.9
4.67
18
8.76		 13.8
7.32
6.41
5.83		 9.95
10.2
7.01
8.23		 12.3
6.91
6.82
4.38		 21
20.8
9.66
11.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030120 Linoleic acid -
36.2
-
43.6		 41.9
48.6
49.7
43.1		 43.3
35.2
46.2
50.3		 39.2
34.4
35.1
41.8		 34.2
41.6
41.8
41.7		 38.5
40.4
46
50.1		 39.6
40.5
41.6
57.8		 36.9
48.5
41.3
52.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010017 Margaric acid -
14.3
-
14.1		 10.4
14.9
9.74
8.41		 13.2
11.8
13.7
13.6		 9.26
10.4
9.6
9.31		 11.5
12.6
12.3
10.2		 13.2
12.3
14.5
14.6		 14
11.4
19.1
11.7		 18.2
15.8
12.9
16.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010014 Myristic acid -
54.6
-
37.8		 153
111
61.3
28.3		 119
62.8
68.1
148		 43.1
88.6
98.4
98.9		 97.9
88.6
41.7
32.6		 66.6
62.3
144
141		 120
71.7
94.6
67.2		 140
77.8
68.7
84.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030002 Oleic acid -
655
-
475		 818
877
602
504		 694
691
585
726		 670
630
505
605		 697
660
484
542		 696
678
646
633		 757
668
618
718		 913
772
637
644		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010001 Palmitic acid -
806
-
592		 1006
1124
641
506		 997
762
697
762		 703
650
645
671		 870
770
603
538		 840
788
1066
1063		 1010
860
1095
828		 1340
954
956
901		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010015 Pentadecanoic acid -
19.1
-
15.9		 20.9
25.5
10.7
7.91		 19.2
11.1
10.9
20.8		 3.43
11.5
12.3
6.53		 21.8
15.1
11.6
8.86		 7.09
19.2
20.9
27		 19.1
5.96
21.5
16.3		 15.5
12.8
10.9
20.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010018 Stearic acid -
620
-
608		 553
656
556
602		 523
629
636
550		 551
557
525
479		 516
533
635
506		 667
644
625
699		 759
661
699
611		 957
825
644
682		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01030357 Stearidonic acid -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 0.4
-
-
0.21		 -
-
-
-		 -
0.09
-
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMFA01010023 Tricosanoic acid -
1.57
-
1.06		 0.08
1.5
0.99
1.31		 1.3
0.245
0.79
1.12		 1.15
0.67
0.175
0.225		 3.49
0.4
0.09
0.14		 1.21
1.91
1.17
1.32		 1.1
0.995
0.75
0.715		 0.95
-
0.43
0.63		 pmol/sample