Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Averages of biological replicates - (GP) Glycerophospholipids Legend: : View data/graphs for replicates : View time course graphs for averages of biological replicates Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 PA | PC | PE | PG | PI | PS | DNA Details Time course graph (ave of biol. reps) LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(32:0) - 70.6 - 76.9 57.2 78.7 77.1 52.4 77 71.7 56.1 77.3 49.7 64.3 68.7 52.5 57.9 55.3 91.4 58.4 75.6 76.3 91.5 52.2 94.6 80.3 111 74.8 121 75.5 115 68 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(32:1) - 47.9 - 58.4 34.4 44.3 42.7 32.8 41.3 47.6 41.6 46.9 25.8 33 37.6 32.4 30.8 27.3 45.5 33.5 34.9 38.2 36.2 25.8 39.2 46 39.2 41.6 52.3 45.2 41.6 37.1 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(34:1) - 127 - 131 118 158 150 110 136 120 117 140 79.6 89.2 120 108 71.9 74.7 114 82.1 85.9 98.2 75.7 61 125 139 111 98.4 167 121 120 122 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(34:2) - 21.9 - 20.6 18.9 20.7 20.1 17.7 26.9 17.2 15.7 21 17.9 17.4 17.4 15 10.8 17.4 20.2 13 12.5 13.2 15.4 14.3 12.9 18.4 13.5 13.8 27.5 23.9 13.1 12.6 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(36:0) - 43.3 - 45 31.5 53.6 55.9 32.9 43.8 71 39.8 75.1 49.6 46.2 48.8 41 25.2 49.1 64 34.1 14.2 19.6 11.6 10.2 14.1 16.4 24.2 14.6 26.6 19.6 11.1 9.96 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(36:1) - 208 - 256 216 274 268 182 247 193 197 238 125 131 189 190 108 109 168 117 131 147 96.4 81 208 240 156 132 274 208 208 202 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(36:2) - 97.6 - 117 102 124 120 88.4 115 92.2 91.9 105 60.8 68.7 83.9 85.7 51.4 51.8 82.9 58.4 58.7 68.5 46.2 58.9 84.5 96.4 64.4 58 91.8 83.4 85 87.9 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(38:3) - 47 - 32.2 49.1 47.7 34.8 34.2 34 30.2 43.7 45.4 19 12.6 20.3 42.1 14.5 13.8 13.8 12.1 16.4 14.5 15 13.2 49.8 61 16.1 16.1 51 38.9 49 47.8 pmol/sample Ratio plot Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp - PA(38:4) - 37.8 - 53.1 35.7 43.1 47.6 34.8 37.7 44.6 30 53.7 28.1 25.8 45.9 40.7 23 25.4 35 32.3 25.9 16.7 32 43.8 25.8 24.6 23.9 18.8 34.5 48.6 28.2 30.4 pmol/sample