Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Averages of biological replicates - (SP) Sphingolipids

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
DetailsTime course graph
(ave of biol. reps) 		LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs
Units
. . . .

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010001 C14 Cer -
0.383
-
0.297		 0.37
0.403
0.35
0.387		 0.4
0.37
0.393
0.387		 0.45
0.407
0.333
0.333		 0.39
0.4
0.36
0.31		 0.413
0.387
0.337
0.353		 0.457
0.377
0.387
0.287		 0.39
0.41
0.347
0.293		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010004 C16 Cer -
37.8
-
34.6		 39.4
44.5
33
28.9		 43.6
42.2
34.3
37.1		 46.7
45.2
31.7
35		 43.7
48.6
33.1
31.3		 50.8
41.4
36.7
33.3		 56.6
43.6
42.9
33		 54.1
39.1
44.2
32.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010003 C18:1 Cer -
0.193
-
0.247		 0.21
0.227
0.223
0.21		 0.227
0.253
0.217
0.2		 0.253
0.217
0.233
0.207		 0.223
0.217
0.23
0.16		 0.153
0.167
0.237
0.177		 0.183
0.177
0.153
0.24		 0.217
0.183
0.183
0.173		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010006 C18 Cer -
2.85
-
2.5		 2.93
3.19
2.36
2.03		 3.28
3.33
2.62
2.66		 3.7
3.21
2.45
2.41		 3.14
3.56
2.38
2.17		 3.33
3.08
2.2
2.39		 3.25
3.26
2.91
2.3		 3.64
3.44
2.43
2.14		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010007 C20 Cer -
1.39
-
1.19		 1.43
1.59
1.09
0.91		 1.5
1.48
1.22
1.14		 1.72
1.48
1.12
1.14		 1.52
1.64
1.22
1.03		 1.7
1.5
1.11
1.16		 1.95
1.44
1.4
1.15		 1.97
1.56
1.36
0.983		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010008 C22 Cer -
15.6
-
12.8		 15.6
17.3
10.8
9.81		 13.9
16.8
10.8
12.4		 17.8
15.9
11.2
12.1		 16.5
19.1
11.3
12		 18.3
16.9
13
12		 21.5
16.1
15.3
12.9		 25.5
15.8
15.1
11.5		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010009 C24:1 Cer -
47.8
-
45.4		 53.2
56.6
40.5
36.6		 49.3
53.6
39
45.4		 52.6
55.3
34.8
46.5		 47.2
60.2
33.8
42.9		 57.7
55.4
39.6
42.3		 69.3
54.7
55.1
48.7		 94.4
52
59.8
50.9		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010012 C24 Cer -
35.8
-
31.3		 35.1
38.5
26.2
24		 32.9
36.8
25.8
29.1		 36.7
33.2
27.1
27.4		 36.2
41.2
26.5
30.7		 43.8
33.9
34.7
30.6		 53.3
33
41.4
30.9		 61.2
30.8
40.8
26.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010010 C26:1 Cer -
0.553
-
0.583		 0.58
0.687
0.53
0.467		 0.617
0.663
0.577
0.55		 0.757
0.62
0.603
0.527		 0.713
0.73
0.727
0.59		 0.85
0.71
0.973
0.617		 0.907
0.647
0.853
0.687		 0.957
0.443
0.727
0.52		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02010011 C26 Cer -
0.37
-
0.233		 0.237
0.243
0.203
0.187		 0.257
0.277
0.237
0.2		 0.327
0.307
0.247
0.2		 0.327
0.303
0.273
0.257		 0.403
0.27
0.457
0.49		 0.41
0.213
0.35
0.307		 0.493
0.2
0.333
0.19		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010028 C14 Sphingomyelin -
17.1
-
22.3		 19.3
18.6
22.9
20.6		 19
17.3
23.3
23.7		 18.7
18.1
22.8
22.8		 19
17.6
24.5
22		 17.3
17.9
23.7
25.7		 16.9
17.5
19.6
26.9		 12.1
15.8
16.4
24.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010003 C16 Sphingomyelin -
1499
-
1360		 1434
1549
1375
1187		 1456
1330
1410
1404		 1539
1441
1352
1377		 1624
1514
1511
1360		 1607
1559
1557
1570		 1595
1496
1563
1634		 1224
1572
1345
1491		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010029 C18:1 Sphingomyelin -
5.39
-
7.56		 5.47
5.92
6.74
6.76		 5.72
5.64
7.06
7.02		 5.54
5.7
6.75
7.43		 5.44
5.34
7.16
6.79		 4.9
5.01
7.41
6.99		 4.72
4.8
5.76
7.98		 3.45
4.66
5.83
6.87		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010001 C18 Sphingomyelin -
104
-
92		 94.1
102
84.4
79.9		 98.1
93.3
92
91.9		 104
97.1
88.8
92.9		 112
102
101
87.6		 103
106
101
107		 105
101
105
111		 78.6
106
86
94.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010005 C20 Sphingomyelin -
33.8
-
30.1		 32.2
35.2
28.7
25.7		 33.2
32.2
32.3
31.8		 36.8
32.1
30.9
33.6		 40.2
36.2
35.8
31.3		 36.4
35.2
37.2
37		 38.9
35.4
37.6
40.9		 28.2
36.9
31.1
34		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010006 C22 Sphingomyelin -
224
-
173		 196
209
163
139		 196
186
192
184		 232
210
181
199		 256
227
215
186		 228
218
226
214		 252
223
235
251		 189
242
200
204		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010007 C24:1 Sphingomyelin -
479
-
473		 462
481
434
393		 489
485
485
473		 521
510
460
510		 569
500
519
481		 547
517
535
507		 617
568
561
577		 495
564
491
522		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010008 C24 Sphingomyelin -
201
-
177		 192
212
166
148		 195
191
194
183		 226
205
180
206		 269
225
210
198		 234
220
237
224		 279
248
244
248		 205
248
219
214		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010009 C26:1 Sphingomyelin -
11.4
-
11.4		 8.75
9.27
8.63
8.74		 8.76
8.61
9.4
9.44		 9.33
8.99
8.32
9.14		 10.6
9.79
9.97
8.5		 9.43
8.7
10.1
12.5		 9.63
9.8
9.91
10.8		 7.93
9.42
8.41
9.27		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010010 C26 Sphingomyelin -
4.38
-
4.23		 4.46
4.84
4.15
3.69		 4.87
4.59
4.92
4.51		 5.06
4.92
4.36
5.07		 5.36
5.11
4.95
4.61		 5.03
4.9
5.52
5.56		 5.6
5.4
5.24
5.77		 4.08
5.1
4.4
4.83		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA26 C14 GlcCer -
0.155
-
0.113		 0.143
0.14
0.187
0.13		 0.197
0.16
0.157
0.127		 0.173
0.11
0.115
0.13		 0.12
0.137
0.15
0.107		 0.117
0.14
0.135
0.227		 0.093
0.12
0.137
0.167		 0.09
0.143
0.1
0.173		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA03 C16 GlcCer -
35.4
-
33.6		 34.5
33.1
33.5
28.5		 32.7
29.7
32.1
31.8		 35.2
33.4
29.7
29.5		 37.2
33.6
36.8
30.7		 32.7
31.8
35.4
37.9		 31.9
34.4
35.3
37.2		 23
37.5
40.1
35.5		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA27 C18:1 GlcCer -
0.07
-
0.08		 0.075
0.075
0.075
0.07		 0.08
0.08
0.07
0.07		 0.08
0.07
0.06
-		 0.07
0.07
0.065
0.05		 -
0.07
-
0.06		 -
0.05
-
0.07		 0.05
0.07
-
0.05		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA05 C18 GlcCer -
4.86
-
4.11		 4.52
4.2
4.08
3.5		 4
3.54
3.73
3.88		 4.34
4.2
3.68
3.32		 4.71
4.11
4.6
3.84		 3.5
3.47
3.91
4.55		 3.44
3.84
3.57
4.19		 3.05
4.6
3.93
3.89		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA06 C20 GlcCer -
4.34
-
3.51		 3.71
3.7
3.32
2.93		 3.25
2.95
3.35
3.16		 3.73
3.84
3.43
2.93		 4.49
3.71
4.22
3.35		 3.4
3.05
3.58
4.41		 3.28
3.32
3.47
3.85		 2.96
4.15
4.2
3.58		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA07 C22 GlcCer -
34.5
-
27.2		 28.4
28.2
27.5
23.9		 25.2
24
28
27.9		 29.1
29.6
27.3
23		 35.9
29.6
37.1
28.2		 29
24.2
32.1
37.7		 28.4
29.4
29.5
34.6		 29
36.4
43.6
31.3		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA08 C24:1 GlcCer -
29.5
-
31.3		 33.5
27.8
37.3
26.2		 29.5
27.4
34.2
34.8		 30.7
31
32.2
29.3		 31.7
28.9
38.2
32.7		 29.4
26.4
32.2
36		 29.7
31.1
32.7
34.8		 29.2
35.5
45.5
36.8		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA09 C24 GlcCer -
42.4
-
35.9		 31.5
31.8
36.6
28.9		 28
26.7
38.2
35.5		 32.6
34.5
38.7
31.1		 42.1
35
47
38.3		 32.3
30.8
45.9
51.8		 38.4
37.2
44.1
46.8		 38.2
43.7
74.2
47.2		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA10 C26:1 GlcCer -
0.61
-
0.41		 0.477
0.457
0.517
0.32		 0.363
0.5
0.543
0.45		 0.42
0.43
0.403
0.437		 0.453
0.49
0.557
0.45		 0.42
0.5
0.653
0.63		 0.55
0.523
0.73
0.617		 0.497
0.453
0.98
0.79		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA11 C26 GlcCer -
0.49
-
0.227		 0.193
0.257
0.247
0.167		 0.205
0.195
0.33
0.26		 0.197
0.24
0.205
0.265		 0.267
0.18
0.3
0.217		 0.207
0.217
0.353
0.443		 0.355
0.243
0.535
0.357		 0.385
0.223
0.623
0.515		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050002 C16 CerP -
0.57
-
0.597		 0.65
0.583
0.567
0.55		 0.617
0.567
0.497
0.557		 0.49
0.583
0.487
0.517		 0.523
0.593
0.433
0.46		 0.473
0.48
0.437
0.507		 0.43
0.503
0.427
0.697		 0.393
0.43
0.417
0.44		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050003 C16 DHCerP -
-
-
0.02		 -
-
0.01
0.03		 0.02
0.02
-
0.01		 -
-
-
0.02		 0.01
0.01
-
-		 0.01
0.01
-
0.03		 0.01
-
-
0.04		 -
-
-
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050004 C18 CerP -
0.13
-
0.137		 0.12
0.117
0.127
0.117		 0.117
0.11
0.117
0.127		 0.107
0.107
0.107
0.113		 0.113
0.13
0.1
0.093		 0.097
0.097
0.11
0.133		 0.1
0.097
0.103
0.117		 0.083
0.077
0.07
0.11		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050005 C20 CerP -
0.02
-
0.013		 0.013
0.01
0.013
0.013		 0.017
0.013
0.013
0.02		 0.015
0.017
0.015
0.02		 0.01
0.01
0.01
0.01		 0.01
0.01
0.017
0.02		 0.027
0.015
0.01
0.017		 0.015
0.015
0.015
0.01		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050006 C22 CerP -
0.047
-
0.02		 0.053
0.06
0.043
0.057		 0.053
0.05
0.037
0.043		 0.03
0.053
0.043
0.037		 0.043
0.037
0.023
0.03		 0.043
0.037
0.027
0.037		 0.033
0.033
0.03
0.047		 0.03
0.03
0.023
0.035		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050007 C24:1 CerP -
0.093
-
0.087		 0.127
0.107
0.063
0.093		 0.097
0.093
0.057
0.08		 0.093
0.113
0.067
0.083		 0.07
0.077
0.047
0.057		 0.06
0.083
0.05
0.08		 0.067
0.083
0.053
0.1		 0.06
0.07
0.067
0.077		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050008 C24 CerP -
0.17
-
0.17		 0.173
0.183
0.183
0.19		 0.147
0.137
0.14
0.14		 0.157
0.127
0.143
0.143		 0.12
0.117
0.117
0.133		 0.147
0.28
0.137
0.15		 0.175
0.107
0.165
0.133		 0.097
0.107
0.12
0.103		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050011 C26:1 CerP -
-
-
-		 -
-
0.01
0.01		 -
0.01
-
0.01		 -
-
0.01
0.01		 0.01
-
0.01
-		 0.01
-
-
0.01		 -
0.01
0.01
-		 0.01
0.02
-
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050010 C26 CerP -
-
-
-		 -
0.01
-
0.02		 0.01
0.01
0.01
-		 -
0.01
0.01
0.01		 -
0.02
0.01
0.02		 0.01
-
-
0.02		 0.01
-
0.04
0.01		 0.02
0.02
-
0.02		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02050012 C8 CerP -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP05010030 C14DH Cer -
0.48
-
0.337		 0.383
0.4
0.403
0.477		 0.52
0.44
0.407
0.32		 0.457
0.437
0.333
0.363		 0.423
0.367
0.36
0.297		 0.42
0.33
0.327
0.465		 0.33
0.333
0.313
0.31		 0.285
0.253
0.217
0.223		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020001 C16DH Cer -
2.15
-
2.23		 1.85
1.83
2.17
2.28		 2.13
2.68
2.07
2.53		 3.43
3.44
2.78
2.93		 3.69
4.09
3.15
2.51		 3.18
3.79
2.45
2.13		 3.7
3.26
2.39
3.07		 2.7
3.71
2.47
2.02		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020015 C18:1DH Cer -
0.183
-
0.087		 0.183
0.2
0.173
0.307		 0.175
0.2
0.16
0.173		 0.203
0.197
0.197
0.14		 0.173
0.117
0.147
0.207		 0.16
0.14
0.193
0.13		 0.15
0.12
0.17
0.217		 0.177
0.225
0.203
0.12		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020008 C18DH Cer -
0.375
-
0.57		 0.413
0.42
0.46
0.545		 0.507
0.493
0.47
0.487		 0.587
0.577
0.63
0.563		 0.613
0.573
0.49
0.517		 0.48
0.527
0.503
0.335		 0.523
0.56
0.38
0.43		 0.45
0.663
0.413
0.473		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020009 C20DH Cer -
0.18
-
0.23		 0.21
0.183
0.153
0.207		 0.227
0.223
0.18
0.28		 0.233
0.187
0.193
0.24		 0.35
0.26
0.227
0.137		 0.267
0.27
0.177
0.205		 0.263
0.21
0.217
0.263		 0.177
0.203
0.203
0.155		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020010 C22DH Cer -
0.56
-
0.485		 0.56
0.56
0.393
0.47		 0.463
0.537
0.55
0.487		 0.97
0.823
0.69
0.687		 1.3
1.04
0.88
0.793		 1.15
0.873
0.73
0.55		 1.05
0.727
0.817
0.823		 1.1
0.96
0.903
0.563		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020011 C24:1DH Cer -
0.82
-
0.87		 0.5
1.1
1.15
0.985		 0.76
0.903
0.913
1.33		 2.29
2.4
1.47
2.83		 3.06
3.32
2.07
2.12		 2.54
2.86
2.05
1.22		 3.87
2.65
2.37
2.19		 3.36
2.96
2.76
1.83		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020012 C24DH Cer -
0.405
-
0.44		 0.505
0.615
0.65
1.13		 0.395
0.6
0.683
0.727		 2.13
1.5
1.44
1.04		 2.29
2.03
1.5
1.6		 2.15
1.72
1.83
0.865		 2.41
1.25
1.73
1.38		 2.32
1.64
1.52
1.13		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020013 C26:1DH Cer -
0.07
-
0.07		 0.08
0.113
0.1
0.07		 0.09
0.3
0.135
0.095		 0.1
0.45
0.107
0.095		 0.185
0.16
0.085
0.107		 0.3
0.097
0.217
0.15		 0.133
0.1
0.21
0.105		 0.1
0.077
0.13
0.155		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP02020014 C26DH Cer -
0.075
-
0.087		 0.17
0.143
0.205
0.33		 0.2
0.3
0.16
0.23		 0.177
0.155
0.175
0.2		 0.15
0.135
0.133
0.115		 0.255
0.21
0.22
-		 0.15
0.14
0.185
0.42		 0.19
0.187
0.193
0.137		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010030 C14DH Sphingomyelin -
1.88
-
2.8		 2.36
2.39
2.78
2.41		 2.47
2.42
3.01
2.89		 2.58
2.64
2.78
3.1		 2.67
2.72
3.2
3.06		 2.44
2.66
3.12
3.55		 2.37
2.58
2.67
3.36		 1.51
2.03
2.17
2.98		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010004 C16DH Sphingomyelin -
167
-
164		 198
213
176
161		 209
188
194
184		 223
223
182
196		 232
245
218
195		 227
235
221
247		 222
240
229
229		 165
211
179
207		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010031 C18:1DH Sphingomyelin -
97.4
-
94.8		 98.5
100
86.1
87.3		 93.6
92.7
94.1
92.5		 103
101
86.7
97		 107
108
102
89.7		 102
107
97.4
102		 99.7
106
107
108		 86.5
102
86
95.4		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010020 C18DH Sphingomyelin -
13.5
-
11.7		 15.8
16.1
12.9
11.8		 16.6
14.1
14.5
13.9		 17.9
17.3
13.8
15.3		 19.3
19.3
16.6
14.6		 18.2
18.7
17.2
17.7		 18
18.1
18
17.5		 13.9
16.6
13
15.7		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010021 C20DH Sphingomyelin -
47.3
-
52.7		 58.3
57.7
53.9
44		 58.8
53.6
58.8
54.2		 61.5
57.6
51.6
58.7		 67.3
65.1
64.9
55.7		 66
65.3
64.5
73.6		 63.7
67.8
63.9
70.4		 48.7
64.8
53.4
60.6		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010022 C22DH Sphingomyelin -
20.1
-
19.7		 25.5
27.2
20.1
18.9		 25
23.6
24.5
22.3		 29.2
28.5
22.4
25.6		 33.2
32.7
27.4
23.8		 29.5
31.3
28.8
28		 31.8
31.8
30.8
30.9		 25.4
30.4
24.6
26.6		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010023 C24:1DH Sphingomyelin -
168
-
164		 187
203
156
148		 189
177
193
174		 220
215
172
196		 245
238
202
186		 211
220
223
224		 248
241
235
231		 218
218
202
217		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010024 C24DH Sphingomyelin -
13
-
12.3		 16.5
17.9
13.3
12.1		 16.8
15.9
16.4
15.3		 20.1
19.2
15.1
17.5		 22.8
22.3
19
17		 20.3
20
20.9
19.9		 22.9
23.1
21
21.4		 19.5
21
18.5
19.5		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010025 C26:1DH Sphingomyelin -
4.38
-
4.48		 4.4
4.43
3.86
3.51		 4.56
4.4
4.57
4.14		 4.8
4.69
4.08
4.9		 5.13
4.95
4.89
4.56		 4.75
5.01
5.24
6.21		 5
5.43
5.1
5.44		 4.17
4.7
4.11
4.53		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP03010026 C26DH Sphingomyelin -
7.75
-
7.38		 8.73
8.68
7.35
6.38		 8.58
8.08
9.58
7.77		 11.1
8.95
7.57
9.39		 11.1
10.5
9.24
8.53		 10.2
10.8
10.6
12		 11.1
11
11.4
11.2		 8.33
10.4
8.58
9.28		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA28 C14DH GlcCer -
-
-
-		 -
0.06
-
-		 -
-
-
-		 0.08
-
-
-		 -
-
0.04
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA04 C16DH GlcCer -
2.83
-
2.01		 2.63
2.81
2.44
2.88		 2.95
2.4
2.12
3.13		 2.86
2.65
2.14
2.73		 2.53
2.62
3.21
1.77		 1.54
2.03
2.69
1.51		 2.18
2.46
1.85
1.86		 1.04
2.86
2.01
1.81		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA29 C18:1DH GlcCer -
0.193
-
0.13		 0.14
0.133
0.117
0.09		 0.13
0.187
0.127
0.19		 0.177
0.12
0.24
0.167		 0.15
0.16
0.16
0.115		 0.093
0.12
0.135
0.11		 0.077
0.095
0.165
0.143		 0.11
0.17
0.1
0.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA19 C18DH GlcCer -
0.463
-
0.38		 0.66
0.227
0.31
0.43		 0.4
0.36
0.28
0.435		 0.307
0.345
0.275
0.21		 0.433
0.32
0.485
0.64		 0.5
0.33
0.35
-		 0.273
0.48
0.16
0.42		 0.4
0.4
0.32
0.225		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA20 C20DH GlcCer -
0.403
-
0.525		 0.365
0.297
0.49
0.43		 0.507
0.37
0.347
0.58		 0.463
0.277
0.447
0.353		 0.473
0.4
0.357
0.463		 0.31
0.67
0.333
0.31		 0.487
0.24
0.46
0.503		 0.353
0.49
0.575
0.457		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA21 C22DH GlcCer -
1.79
-
0.645		 2.08
2.14
1.68
2.09		 1.6
1.3
1.47
2.33		 1.67
2.13
1.52
1.42		 2.04
2.38
2.98
1.84		 2.21
2.01
2.16
0.73		 1.89
1.88
1.45
2.06		 1.4
2.36
2.32
1.57		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA22 C24:1DH GlcCer -
2.33
-
1.5		 3.46
3.24
3.33
3.71		 2.84
2.38
2.96
4.55		 2.44
3.77
2.96
2.7		 3.42
3.88
5.04
4.42		 2.65
3.74
4.05
2.85		 3.2
2.4
3.41
3.88		 2.22
4.8
4.79
3.93		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA23 C24DH GlcCer -
1.57
-
-		 1.61
1.51
1.51
2.02		 1.37
0.853
2.98
1.71		 1.13
2.41
5.99
2.06		 2.5
3.25
3.01
2.93		 2.21
3.42
2.22
0.62		 1.29
1.84
1.24
3.88		 1.68
2.1
4.18
1.06		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA24 C26:1DH GlcCer -
0.07
-
0.25		 0.087
0.095
-
0.1		 0.16
0.133
0.085
0.67		 0.16
0.2
0.1
0.37		 0.147
0.07
0.16
0.34		 0.145
0.2
0.113
-		 0.2
0.19
0.11
0.11		 -
0.345
0.2
0.1		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP0501AA25 C26DH GlcCer -
2.02
-
1.7		 0.07
1.97
0.22
0.33		 1.96
0.12
5.33
8.13		 2.29
0.09
-
0.76		 -
1.22
1.68
2.82		 0.135
6.3
0.12
0.17		 2.67
5.61
0.05
0.14		 0.075
0.215
0.08
-		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP01020001 Sphinganine -
0.863
-
1.03		 1.01
0.957
1.07
1.04		 1
1.02
1.09
1.16		 1
1.11
1.01
1.04		 0.82
0.977
0.953
0.88		 0.717
0.843
0.77
0.827		 0.673
0.803
0.58
0.743		 0.453
0.703
0.453
0.593		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP01050002 Sphinganine-P -
0.09
-
0.113		 0.13
0.135
0.127
0.105		 0.12
0.113
0.185
0.2		 0.1
0.11
0.123
0.14		 0.073
0.11
0.105
0.115		 0.11
0.12
0.11
0.12		 0.125
0.11
0.05
0.11		 0.11
0.11
0.087
0.103		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP01010001 Sphingosine -
7.63
-
9.69		 8.86
8.65
9.25
10.2		 8.15
8.07
9.32
9.4		 8.71
8.69
8.36
8.46		 8.02
8.22
9.27
8.25		 8.16
8.29
8.27
7.97		 8.32
8.28
8.03
7.97		 7.88
8.28
8.75
8.08		 pmol/sample

Ratio plot
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
LMSP01050001 Sphingosine-P -
0.213
-
0.197		 0.167
0.17
0.177
0.173		 0.167
0.19
0.213
0.247		 0.2
0.22
0.163
0.19		 0.19
0.21
0.19
0.157		 0.193
0.21
0.137
0.177		 0.16
0.21
0.17
0.213		 0.16
0.187
0.133
0.173		 pmol/sample