Lipidomics studies on macrophages - bone marrow-derived macrophages treated with Kdo2-Lipid A and ATP
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Averages of biological replicates - (ST) Cholesteryl esters
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: View time course graphs for averages of biological replicates| Details | Time course graph (ave of biol. reps) | LM_ID | Name | Mass (neutral) |
Kdo+ATP ATP Kdo Ctrl 0 hrs |
Kdo+ATP ATP Kdo Ctrl 15 min |
Kdo+ATP ATP Kdo Ctrl 30 min |
Kdo+ATP ATP Kdo Ctrl 1 hr |
Kdo+ATP ATP Kdo Ctrl 2 hrs |
Kdo+ATP ATP Kdo Ctrl 4 hrs |
Kdo+ATP ATP Kdo Ctrl 8 hrs |
Kdo+ATP ATP Kdo Ctrl 20 hrs | Units . . . . |
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Legend:
 :Ctrl
 :Kdo2-lipid A
 :ATP
 :ATP+Kdo2-lipid A
|
LMST01020004 | CE(14:0) | 596.6 (ions) | - - - 1.14 |
0.923 0.63 0.837 1.06 |
1 0.802 0.803 0.844 |
0.809 0.699 0.977 1.41 |
1.04 0.758 0.767 0.552 |
0.542 0.567 0.756 0.691 |
2.85 1.51 0.815 0.739 |
1.51 1.71 1.55 0.599 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020021 | CE(14:1) | 594.5 (ions) | - - - 0.012 |
0.032 0.016 0.058 0.008 |
0.014 0.026 0.014 0.02 |
0.01 0.011 0.014 0.013 |
0.01 0.006 0.005 - |
0.024 0.041 0.007 - |
0.014 0.006 0.01 0.013 |
0.049 0.013 0.013 0.009 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020027 | CE(15:0) | 610.6 (ions) | - - - 0.067 |
0.206 0.125 0.218 0.173 |
0.166 0.077 0.114 0.148 |
0.116 0.084 0.153 0.186 |
0.103 0.131 0.133 0.135 |
0.089 0.106 0.25 0.073 |
0.872 0.101 0.106 0.096 |
0.142 0.398 0.342 0.062 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020022 | CE(15:1) | 608.6 (ions) | - - - 0.007 |
0.022 0.009 0.054 0.018 |
- - - 0.026 |
0.005 0.006 - 0.009 |
0.039 0.04 - 0.017 |
0.009 0.036 0.044 0.032 |
0.032 0.039 0.024 0.018 |
0.019 0.018 0.017 0.043 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020005 | CE(16:0) | 624.6 (ions) | - - - 2.01 |
2.25 1.81 2.29 1.93 |
2.82 1.65 1.99 1.78 |
1.83 1.4 4.02 3.6 |
1.85 1.07 2.31 3.25 |
1.02 1.25 3.48 1.66 |
26.8 11.2 2.78 2.02 |
3.76 6.58 4.97 1.32 |
pmol/ug DNA |
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|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020006 | CE(16:1) | 622.6 (ions) | - - - 0.669 |
0.818 0.617 1.01 0.838 |
0.781 0.481 0.639 0.54 |
0.572 0.472 1.13 1.31 |
0.414 0.483 0.697 0.832 |
0.454 0.449 0.87 0.49 |
8.57 4.14 0.582 0.35 |
1.43 1.81 1.71 0.387 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020024 | CE(16:2) | 620.6 (ions) | - - - 0.125 |
0.141 0.109 0.169 0.089 |
0.13 0.088 0.118 0.093 |
0.119 0.097 0.17 0.217 |
0.093 0.068 0.128 0.094 |
0.103 0.106 0.136 0.089 |
1.01 0.559 0.131 0.067 |
0.39 0.591 0.356 0.061 |
pmol/ug DNA |
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|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020026 | CE(17:0) | 638.6 (ions) | - - - 0.201 |
0.255 0.206 0.316 0.29 |
0.266 0.173 0.215 0.179 |
0.143 0.145 0.383 0.361 |
0.173 0.15 0.218 0.373 |
0.146 0.175 0.474 0.166 |
1.82 0.656 0.234 0.159 |
0.396 0.66 1.63 0.155 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020023 | CE(17:1) | 636.6 (ions) | - - - 0.155 |
0.188 0.158 0.202 0.175 |
0.184 0.109 0.144 0.129 |
0.123 0.104 0.272 0.316 |
0.117 0.069 0.187 0.168 |
0.097 0.111 0.237 0.105 |
1.58 0.875 0.135 0.104 |
0.253 0.49 0.424 0.098 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020007 | CE(18:0) | 652.6 (ions) | - - - 0.722 |
1.02 0.754 0.983 0.844 |
0.902 0.562 0.744 0.664 |
0.673 0.543 1.12 1.63 |
0.77 0.518 0.9 0.659 |
0.825 0.587 1.62 0.619 |
7.7 3.24 0.956 0.572 |
3.45 4.29 2.18 0.773 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020003 | CE(18:1) | 650.6 (ions) | - - - 3.65 |
5.24 3.94 5.04 5.33 |
4.65 2.78 4.31 3.18 |
3.44 3.16 6.81 8.84 |
4.27 2.68 4.95 4.01 |
4.91 3.05 9.98 2.98 |
41.8 17.7 4.64 3.2 |
17.7 23.8 12.4 4.64 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020008 | CE(18:2) | 648.6 (ions) | - - - 0.517 |
0.708 0.543 0.81 0.689 |
0.489 0.382 0.552 0.441 |
0.381 0.391 0.96 1.2 |
0.366 0.255 0.576 0.47 |
0.309 0.352 1.23 0.417 |
6.45 4.04 0.491 0.347 |
0.919 1.65 1.56 0.426 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020009 | CE(18:3) | 646.6 (ions) | - - - 0.197 |
0.231 0.165 0.228 0.234 |
0.117 0.14 0.164 0.126 |
0.122 0.084 0.174 0.148 |
0.092 0.081 0.161 0.134 |
0.106 0.12 0.306 0.122 |
2.11 1.13 0.117 0.12 |
0.131 0.114 0.137 0.088 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020010 | CE(20:0) | 680.6 (ions) | - - - 0.258 |
0.4 0.171 0.096 0.196 |
0.123 0.17 0.134 0.15 |
0.162 0.184 0.161 0.142 |
0.616 1.89 0.188 0.31 |
0.689 0.759 0.542 0.457 |
0.715 0.96 0.459 0.98 |
0.676 0.531 0.345 0.75 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020011 | CE(20:1) | 678.6 (ions) | - - - 0.098 |
0.113 0.105 0.111 0.155 |
0.096 0.08 0.093 0.1 |
0.128 0.099 0.135 0.241 |
0.135 0.1 0.113 0.084 |
0.262 0.099 0.172 0.088 |
0.705 0.2 0.182 0.08 |
1.43 1.41 0.424 0.226 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020012 | CE(20:2) | 676.6 (ions) | - - - 0.062 |
0.063 0.065 0.063 0.089 |
0.05 0.049 0.051 0.056 |
0.064 0.057 0.076 0.128 |
0.091 0.053 0.056 0.039 |
0.166 0.062 0.131 0.046 |
0.52 0.173 0.077 0.041 |
0.828 0.608 0.177 0.148 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020013 | CE(20:3) | 674.6 (ions) | - - - 0.971 |
0.868 0.791 0.906 1.1 |
0.456 0.528 0.669 0.56 |
0.738 0.549 0.889 1.08 |
0.687 0.417 0.782 0.297 |
1.29 0.59 1.7 0.597 |
10.7 6.18 0.695 0.613 |
3.92 1.77 1.11 0.743 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020014 | CE(20:4) | 672.6 (ions) | - - - 0.571 |
0.851 0.638 1 0.769 |
0.637 0.41 0.674 0.569 |
0.56 0.432 1.1 1.41 |
0.431 0.344 0.78 0.736 |
0.466 0.438 0.77 0.499 |
5.12 3.14 0.643 0.504 |
1.13 1.72 1.85 0.508 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020016 | CE(22:0) | 708.7 (ions) | - - - 0.227 |
0.365 0.241 0.408 0.303 |
0.301 0.177 0.312 0.253 |
0.233 0.189 0.46 0.515 |
0.181 0.15 0.304 0.359 |
0.201 0.203 0.314 0.217 |
2.17 1.16 0.292 0.228 |
0.494 0.755 0.769 0.196 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020025 | CE(22:1) | 706.7 (ions) | - - - 0.031 |
0.017 0.023 0.03 0.029 |
0.019 0.016 0.015 0.02 |
0.02 0.018 0.022 0.035 |
0.021 0.014 0.018 0.017 |
0.033 0.018 0.023 0.014 |
0.098 0.039 0.03 0.015 |
0.341 0.17 0.074 0.022 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020017 | CE(22:2) | 704.6 (ions) | - - - 0.011 |
0.009 0.008 0.012 0.01 |
0.008 0.009 0.006 0.01 |
0.012 0.009 0.009 0.018 |
0.012 0.007 0.008 0.007 |
0.025 0.01 0.008 0.006 |
0.051 0.011 0.01 0.007 |
0.157 0.078 0.025 0.018 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020018 | CE(22:4) | 700.6 (ions) | - - - 0.048 |
0.032 0.032 0.031 0.042 |
0.031 0.024 0.023 0.023 |
0.035 0.028 0.029 0.051 |
0.039 0.023 0.028 0.022 |
0.074 0.026 0.038 0.02 |
0.153 0.06 0.033 0.026 |
0.421 0.176 0.061 0.07 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020031 | CE(22:5) | 698.6 (ions) | - - - 0.063 |
0.066 0.055 0.06 0.076 |
0.054 0.039 0.05 0.043 |
0.06 0.043 0.073 0.098 |
0.067 0.041 0.064 0.054 |
0.112 0.047 0.074 0.042 |
0.4 0.174 0.064 0.045 |
0.644 0.344 0.145 0.099 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020019 | CE(22:6) | 696.6 (ions) | - - - 0.134 |
0.185 0.125 0.217 0.196 |
0.18 0.102 0.153 0.109 |
0.138 0.098 0.246 0.3 |
0.117 0.079 0.173 0.157 |
0.147 0.088 0.217 0.111 |
1.29 0.636 0.153 0.138 |
0.507 0.49 0.417 0.137 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020009 | CE(18:3) | 646.6 (ions) | - - - 0.019 |
0.15 0.112 0.182 0.107 |
0.221 0.033 0.133 0.065 |
0.099 0.117 0.323 0.674 |
0.085 0.054 0.155 0.147 |
0.069 0.065 0.151 0.085 |
0.119 0.104 0.146 0.068 |
0.318 0.634 1.01 0.12 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMST01020010 | CE(20:0) | 680.6 (ions) | - - - 0.017 |
0.083 0.088 0.1 0.039 |
0.088 0.049 0.068 0.036 |
0.051 0.041 0.084 0.142 |
0.092 0.04 0.066 0.071 |
0.065 0.054 0.078 0.05 |
0.171 0.065 0.103 0.053 |
0.356 0.718 0.323 0.092 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
- | DNA | - | - - - 10.6 |
9.6 9.86 10.1 9.53 |
11 10.8 9.3 11.2 |
7.65 9.19 9.94 9.52 |
7.47 7.96 8.5 11.1 |
6.29 9.34 12.5 11.5 |
8.41 9.99 8.94 11.4 |
7.71 10.9 12.7 11.9 |
ug/sample |