Lipidomics studies on macrophages - bone marrow-derived macrophages treated with Kdo2-Lipid A and ATP

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Averages of biological replicates - (SP) Sphingolipids

Legend:graph_icon: View data/graphs for replicatesgraph_icon: View time course graphs for averages of biological replicates
DetailsTime course graph
(ave of biol. reps) 		LM_ID NameMass
(neutral)		 Kdo+ATP
ATP
Kdo
Ctrl
 0 hrs		 Kdo+ATP
ATP
Kdo
Ctrl
 15 min		 Kdo+ATP
ATP
Kdo
Ctrl
 30 min		 Kdo+ATP
ATP
Kdo
Ctrl
 1 hr		 Kdo+ATP
ATP
Kdo
Ctrl
 2 hrs		 Kdo+ATP
ATP
Kdo
Ctrl
 4 hrs		 Kdo+ATP
ATP
Kdo
Ctrl
 8 hrs		 Kdo+ATP
ATP
Kdo
Ctrl
 20 hrs
Units
. . . .
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010001 C14 Cer509.5 (ions) -
-
-
0.034		 0.139
0.106
0.048
0.028		 0.18
0.146
0.024
0.023		 0.253
0.16
0.05
0.034		 0.182
0.142
0.051
0.037		 0.128
0.099
0.039
0.023		 0.106
0.081
0.044
0.032		 0.106
0.075
0.058
0.03		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010004 C16 Cer537.5 (ions) -
-
-
2.48		 15.3
11.9
3.06
2.12		 19.9
17.5
3.01
2.01		 25.4
17.8
3.12
2.33		 25.4
20.6
3.29
2.28		 21.7
14.4
3.56
2.3		 13.1
8.4
5.32
2.78		 15.2
9.55
4.54
3.99		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010003 C18:1 Cer563.5 (ions) -
-
-
0.026		 0.065
0.059
0.034
0.03		 0.121
0.119
0.051
0.023		 0.12
0.07
0.036
0.035		 0.115
0.087
0.039
0.03		 0.076
0.048
0.048
0.038		 0.082
0.074
0.034
0.023		 0.125
0.059
0.036
0.035		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010006 C18 Cer565.5 (ions) -
-
-
0.156		 0.904
0.776
0.27
0.158		 1.21
1.19
0.184
0.158		 1.64
1.14
0.212
0.191		 1.78
1.46
0.255
0.194		 1.81
1.2
0.228
0.211		 1.24
0.763
0.324
0.201		 1.43
0.794
0.232
0.234		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010007 C20 Cer593.6 (ions) -
-
-
0.098		 0.385
0.29
0.092
0.087		 0.549
0.482
0.087
0.092		 0.688
0.56
0.127
0.079		 0.753
0.63
0.133
0.13		 0.804
0.607
0.099
0.098		 0.593
0.353
0.141
0.085		 0.598
0.393
0.111
0.089		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010008 C22 Cer621.6 (ions) -
-
-
1.06		 2.99
2.81
1.04
0.925		 4.28
3.63
0.878
0.623		 5.99
4.63
0.96
0.775		 6.79
4.99
1.04
0.95		 6.52
5.08
0.923
0.972		 4.47
2.45
1.24
1.12		 5.05
2.7
0.911
0.835		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010009 C24:1 Cer647.6 (ions) -
-
-
2.26		 7.88
7.33
1.91
2.02		 12.1
10.1
1.73
1.69		 13.4
11.5
2.03
1.87		 14.7
12.5
1.85
2.04		 13.3
11.2
1.95
2.1		 8.25
4.74
2.61
2.64		 8.61
5.07
2.77
2.92		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010012 C24 Cer649.6 (ions) -
-
-
1.94		 3.81
3.46
1.99
1.78		 5.28
4.42
1.76
1.3		 6.16
5.52
2.05
1.64		 6.97
6.28
2.02
1.88		 7.57
6.44
1.82
1.94		 5.01
2.54
2.79
2.01		 4.58
3.23
1.75
1.27		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010010 C26:1 Cer675.7 (ions) -
-
-
0.045		 0.1
0.094
0.058
0.042		 0.22
0.108
0.036
0.04		 0.161
0.162
0.068
0.042		 0.177
0.178
0.058
0.04		 0.175
0.122
0.078
0.046		 0.099
0.12
0.067
0.045		 0.12
0.068
0.048
0.042		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02010011 C26 Cer677.7 (ions) -
-
-
0.043		 0.059
0.051
0.029
0.024		 0.066
0.06
0.024
0.017		 0.082
0.04
0.03
0.012		 0.09
0.046
0.025
0.034		 0.081
0.039
0.023
0.035		 0.042
0.044
0.047
0.02		 0.064
0.039
0.019
0.02		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010028 C14 Sphingomyelin674.5 (ions) -
-
-
1.58		 1.96
1.46
1.64
1.6		 1.88
1.36
1.59
1.39		 1.57
1.26
1.63
1.48		 1.39
1.15
1.74
1.51		 1.34
1.21
1.81
1.48		 1.96
1.58
1.93
1.65		 1.84
1.76
1.97
2		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010003 C16 Sphingomyelin702.6 (ions) -
-
-
88.3		 114
83.9
88.3
95.2		 104
79.7
90.7
77.7		 88.4
75.5
89.6
82.1		 74.1
59.6
91.8
86.4		 72.7
67.5
88.8
82.9		 94.9
81.1
94.6
92.2		 95.9
97.4
102
103		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010029 C18:1 Sphingomyelin728.6 (ions) -
-
-
0.616		 0.634
0.485
0.582
0.549		 0.583
0.465
0.579
0.495		 0.495
0.406
0.571
0.545		 0.448
0.381
0.596
0.497		 0.43
0.405
0.553
0.513		 0.821
0.606
0.539
0.527		 0.746
0.632
0.557
0.598		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010001 C18 Sphingomyelin730.6 (ions) -
-
-
6.03		 7.23
5.69
6.19
6.28		 6.78
5.22
6.13
5.32		 6.18
4.78
5.8
5.75		 4.56
4.03
6.05
5.42		 4.85
4.37
5.47
5.28		 6.93
5.87
5.87
6.11		 8.5
7.1
5.98
5.15		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010005 C20 Sphingomyelin758.6 (ions) -
-
-
2.21		 2.76
2.03
2.33
2.28		 2.45
1.88
2.3
1.87		 2.09
1.76
2.07
1.9		 1.66
1.37
2.24
2.01		 1.75
1.58
2.01
1.89		 2.41
1.99
2.07
2.25		 2.54
2.42
2.17
1.75		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010006 C22 Sphingomyelin786.7 (ions) -
-
-
13		 15.1
11.5
12.9
13		 13.3
10.8
12
10.8		 11.4
9.23
11.8
11.4		 8.97
8.04
12.6
11.4		 10.2
8.56
10.4
11.1		 12.7
10.1
10.9
12.5		 11.1
12
11.6
8.58		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010007 C24:1 Sphingomyelin812.7 (ions) -
-
-
49.2		 51.4
39
46.3
43		 45.5
37.3
43.8
41.3		 38
33.1
43.8
42.9		 32.5
31
43.1
40.1		 34.6
33.8
39.3
41		 46.6
37.3
39.9
44.6		 41
40.4
43.4
39.9		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010008 C24 Sphingomyelin814.7 (ions) -
-
-
17.3		 19.3
14.8
16.8
16.8		 16.9
13.6
15.3
14.7		 14.9
12
15.6
15		 11.3
10.5
15.8
14.7		 12.8
11.4
12.8
14.2		 16.1
12.8
14.3
16.2		 13.6
14.5
15.5
12.1		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010009 C26:1 Sphingomyelin840.7 (ions) -
-
-
0.518		 0.541
0.442
0.527
0.436		 0.507
0.412
0.476
0.416		 0.397
0.365
0.458
0.473		 0.381
0.331
0.484
0.438		 0.353
0.333
0.412
0.432		 0.474
0.364
0.438
0.434		 0.427
0.423
0.419
0.383		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010010 C26 Sphingomyelin842.7 (ions) -
-
-
0.139		 0.162
0.105
0.14
0.143		 0.143
0.134
0.138
0.119		 0.152
0.108
0.139
0.139		 0.112
0.096
0.142
0.121		 0.106
0.103
0.12
0.118		 0.13
0.107
0.121
0.153		 0.132
0.114
0.124
0.106		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA26 C14 GlcCer671.5 (ions) -
-
-
0.033		 0.022
0.01
0.019
0.014		 0.019
0.093
0.031
0.015		 0.035
0.005
0.013
0.045		 0.005
0.041
0.008
0.014		 0.041
0.024
0.005
0.003		 0.039
0.031
0.004
0.008		 0.074
0.043
0.056
0.032		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA03 C16 GlcCer699.6 (ions) -
-
-
3.26		 4.11
2.92
3.87
3.17		 3.72
2.64
3.31
2.74		 3.71
3.04
3.8
2.89		 3.59
3.25
3.5
2.62		 4.04
4.2
3.41
2.91		 6.48
5.48
3.6
3.01		 5.26
5.68
3.72
3.44		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA27 C18:1 GlcCer725.6 (ions) -
-
-
0.079		 0.02
0.129
0.045
0.03		 0.015
0.076
0.025
0.03		 0.045
0.043
0.05
0.017		 0.025
0.146
0.044
0.005		 0.046
0.008
0.077
0.051		 0.032
0.07
0.057
0.026		 0.072
0.033
0.027
0.094		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA05 C18 GlcCer727.6 (ions) -
-
-
0.462		 0.391
0.31
0.449
0.406		 0.428
0.377
0.407
0.282		 0.404
0.326
0.438
0.288		 0.412
0.308
0.352
0.319		 0.448
0.521
0.331
0.321		 0.759
0.679
0.346
0.298		 0.86
0.768
0.327
0.295		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA06 C20 GlcCer755.6 (ions) -
-
-
0.367		 0.428
0.321
0.427
0.372		 0.399
0.369
0.382
0.276		 0.328
0.351
0.409
0.331		 0.359
0.343
0.375
0.348		 0.425
0.397
0.375
0.323		 0.694
0.479
0.328
0.427		 0.627
0.678
0.304
0.22		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA07 C22 GlcCer783.7 (ions) -
-
-
3.01		 3.48
2.76
3.81
3.58		 3.34
2.73
2.88
2.48		 2.8
2.67
3.35
2.52		 2.63
2.74
2.74
2.77		 3.59
3.55
2.7
2.67		 5.42
3.81
2.6
3.09		 3.69
4.53
2.85
1.99		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA08 C24:1 GlcCer809.7 (ions) -
-
-
3.07		 2.72
2.63
2.68
3.07		 2.93
2.28
2.56
2.29		 2.58
2.32
2.86
2.59		 2.64
2.68
2.66
2.41		 3.3
3.98
2.44
2.43		 5.07
4.57
2.04
2.6		 2.75
3.4
2.6
2.1		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA09 C24 GlcCer811.7 (ions) -
-
-
3.63		 3.66
3.39
3.71
3.94		 3.63
2.73
2.97
2.71		 3.03
3.02
3.47
2.92		 2.57
2.99
3.05
3.05		 3.46
3.56
2.7
2.9		 4.64
3.53
2.83
3.39		 2.96
4.13
3.06
1.95		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA10 C26:1 GlcCer837.7 (ions) -
-
-
0.047		 0.068
0.068
0.049
0.044		 0.065
0.067
0.059
0.056		 0.038
0.078
0.081
0.054		 0.058
0.067
0.044
0.069		 0.049
0.047
0.045
0.051		 0.094
0.074
0.056
0.091		 0.048
0.048
0.084
0.025		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA11 C26 GlcCer839.7 (ions) -
-
-
0.02		 0.019
0.031
0.037
0.037		 0.038
0.037
0.036
0.076		 0.029
0.04
0.031
0.037		 0.031
0.038
0.021
0.033		 0.06
0.018
0.01
0.028		 0.065
0.035
0.048
0.022		 0.027
0.025
0.025
0.016		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050002 C16 CerP617.5 (ions) -
-
-
0.047		 1.17
1.33
0.063
0.073		 1.35
1.34
0.058
0.054		 1.41
1.77
0.048
0.036		 1.03
1.48
0.058
0.055		 0.332
0.541
0.035
0.044		 0.154
0.167
0.036
0.038		 0.112
0.15
0.043
0.054		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050004 C18 CerP645.5 (ions) -
-
-
0.015		 0.053
0.047
0.02
0.013		 0.042
0.048
0.015
0.011		 0.038
0.036
0.016
0.008		 0.027
0.036
0.007
0.011		 0.015
0.013
0.019
0.008		 0.026
0.018
0.011
0.013		 0.023
0.013
0.015
0.011		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050005 C20 CerP673.5 (ions) -
-
-
0.004		 0.025
0.024
0.005
0.007		 0.009
0.015
0.011
0.006		 0.025
0.013
0.006
0.005		 0.017
0.02
0.002
0.006		 0.005
0.01
0.007
0.003		 -
0.003
0.002
0.006		 0.011
0.004
0.002
0.011		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050006 C22 CerP701.6 (ions) -
-
-
0.001		 0.001
0.003
0.001
0.001		 0.004
0.003
0.001
0.001		 -
0.003
-
-		 0.004
0.001
0.001
0.001		 0.002
0.001
0.001
0.001		 0.002
0.001
0.001
0.001		 0.001
0.002
0.001
0.001		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050007 C24:1 CerP727.6 (ions) -
-
-
0.001		 0.001
0.002
0.001
0.001		 0.003
0.001
0.001
0.001		 0.006
0.008
0.004
0.001		 0.002
0.016
0.001
0.002		 0.002
0.002
0.003
0.004		 0.007
0.006
0.004
0.004		 0.006
0.008
0.003
0.003		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050008 C24 CerP729.6 (ions) -
-
-
0.002		 -
0.002
0.001
0.001		 -
-
-
-		 0.001
0.006
-
-		 0.001
-
-
0.006		 0.002
-
0.009
0.005		 0.001
0.003
-
0.001		 -
-
-
-		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050011 C26:1 CerP783.7 (ions) -
-
-
0.001		 0.001
0.001
0.001
0.002		 0.005
0.001
0.001
0.001		 0.001
0.002
0.002
0.001		 0.001
0.001
0
0.001		 0.002
0.001
0.001
0.002		 0.001
0
0.001
0.002		 0.001
0.002
0.002
0.004		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02050010 C26 CerP757.6 (ions) -
-
-
-		 -
0.002
0.001
0.002		 0.004
-
0.002
0.001		 -
-
-
0.001		 0.003
-
0.001
-		 -
0.002
-
0.001		 -
0.001
-
0.002		 0.003
-
0.001
-		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP05010030 C14DH Cer- -
-
-
0.115		 0.202
0.143
0.122
0.093		 0.241
0.141
0.048
0.084		 0.114
0.134
0.233
0.117		 0.201
0.226
0.257
0.163		 0.223
0.182
0.068
0.054		 0.189
0.233
0.064
0.177		 0.145
0.099
0.057
0.04		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020001 C16DH Cer539.5 (ions) -
-
-
2.87		 8.88
5.52
3.15
2.81		 10.1
7.05
3.37
1.93		 9.41
9.39
3.46
2.4		 11.2
7.74
4.7
2.16		 11.8
9.07
6.03
3.41		 11.8
7.27
8
2.32		 15.4
8.97
7.91
2.76		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020015 C18:1DH Cer565.5 (ions) -
-
-
0.193		 0.177
0.097
0.1
0.067		 0.103
0.123
0.165
0.074		 0.074
0.24
0.101
0.13		 0.191
0.21
0.09
0.219		 0.221
0.127
0.099
0.112		 0.187
0.091
0.135
0.188		 0.209
0.183
0.169
0.111		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020008 C18DH Cer567.6 (ions) -
-
-
0.387		 0.927
0.557
0.375
0.246		 0.885
0.388
0.468
0.24		 0.646
0.975
0.341
0.163		 0.73
0.955
0.558
0.377		 1.18
0.835
0.764
0.282		 2.19
0.682
0.835
0.461		 1.64
0.948
0.712
0.26		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020009 C20DH Cer595.6 (ions) -
-
-
0.115		 0.172
0.335
0.155
0.228		 0.286
0.315
0.228
0.137		 0.289
0.208
0.093
0.231		 0.329
0.253
0.146
0.159		 0.36
0.23
0.167
0.172		 0.475
0.252
0.462
0.175		 0.472
0.258
0.243
0.135		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020010 C22DH Cer623.6 (ions) -
-
-
0.448		 0.953
0.81
0.761
0.443		 0.924
0.63
0.707
0.725		 1.24
1.31
0.59
0.416		 1.36
1.11
0.979
0.38		 1.48
1.22
0.975
0.514		 1.84
0.783
0.885
0.464		 1.8
0.903
0.973
0.435		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020011 C24:1DH Cer649.6 (ions) -
-
-
0.858		 1.88
2.23
0.982
0.574		 2.85
2.44
0.894
0.802		 2.85
3.43
0.739
0.994		 2.74
2.06
1.05
0.526		 2.81
2.72
1.5
0.887		 2.08
1.55
1.33
1.05		 2.6
1.83
1.44
0.808		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020012 C24DH Cer651.7 (ions) -
-
-
0.602		 0.586
1.01
0.913
0.554		 0.854
0.877
0.75
0.642		 1.02
1
0.581
0.243		 0.999
0.51
0.882
0.641		 0.753
1.2
0.994
0.981		 1.33
0.669
1.23
0.707		 1.09
1.02
0.984
0.439		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020013 C26:1DH Cer677.7 (ions) -
-
-
0.046		 0.042
0.332
0.011
0.009		 0.592
0.009
0.066
0.088		 0.145
0.135
0.029
0.049		 0.037
0.119
0.615
0.074		 -
0.062
0.062
0.032		 0.035
0.037
0.043
0.045		 0.061
0.094
0.026
0.033		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP02020014 C26DH Cer679.7 (ions) -
-
-
0.11		 0.037
0.084
0.033
0.041		 0.012
0.043
0.014
0.024		 0.054
0.085
0.023
0.016		 0.038
0.035
0.04
0.014		 0.074
0.007
0.06
0.056		 0.097
0.033
0.186
0.03		 0.085
0.006
0.125
0.045		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010030 C14DH Sphingomyelin676.6 (ions) -
-
-
0.226		 0.268
0.197
0.235
0.208		 0.261
0.196
0.227
0.212		 0.232
0.211
0.253
0.198		 0.168
0.145
0.226
0.198		 0.183
0.159
0.25
0.183		 0.27
0.18
0.254
0.2		 0.243
0.199
0.266
0.215		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010004 C16DH Sphingomyelin704.6 (ions) -
-
-
16		 20.5
16
18.5
16.3		 19.3
14.8
17.3
14.8		 17.7
14.8
17.7
15.2		 13.6
11.5
17.6
14.5		 12.7
12.2
19.3
15		 18.4
14
20.2
16.9		 16.6
15.2
21.8
18.1		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010031 C18:1DH Sphingomyelin730.6 (ions) -
-
-
7.49		 9.88
7.38
8.22
7.88		 9.15
7.29
7.76
6.9		 8.29
6.85
8.12
7.22		 6.38
5.6
7.81
6.97		 6.22
6.21
7.98
7.11		 9.66
7.54
8.46
8.26		 10.5
9.19
8.1
3.38		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010020 C18DH Sphingomyelin732.6 (ions) -
-
-
1.04		 1.4
1.08
1.24
1.15		 1.32
0.984
1.22
0.969		 1.23
1.09
1.16
1.02		 0.957
0.785
1.25
0.948		 0.895
0.859
1.23
1.02		 1.38
1.04
1.18
1.19		 1.32
1.16
1.17
0.881		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010021 C20DH Sphingomyelin760.6 (ions) -
-
-
0.911		 1.46
1.02
1.14
1		 1.32
0.931
1.13
1.03		 1.16
0.848
1.14
1		 1.05
0.847
1.15
0.948		 0.777
0.846
1.19
0.973		 1.14
0.928
1.28
1.22		 1.1
1.18
1.3
1.08		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010022 C22DH Sphingomyelin788.7 (ions) -
-
-
1.69		 2.2
1.7
1.83
1.8		 1.93
1.62
1.79
1.6		 1.86
1.5
1.84
1.62		 1.29
1.2
1.81
1.49		 1.34
1.2
1.64
1.54		 1.78
1.41
1.75
1.94		 1.58
1.66
1.91
1.15		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010023 C24:1DH Sphingomyelin814.7 (ions) -
-
-
18.6		 22.7
17.7
20
19.1		 20.6
16.2
18.8
17.7		 17.9
15.6
19.2
17.5		 13.4
12.8
18.2
16.6		 14.2
13.6
17.2
16.8		 18.4
14.3
17.6
19.5		 14.6
16
19.7
13.1		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010024 C24DH Sphingomyelin816.7 (ions) -
-
-
1.53		 1.97
1.46
1.65
1.66		 1.66
1.42
1.53
1.45		 1.45
1.26
1.43
1.47		 1.04
1.02
1.45
1.35		 1.19
1.17
1.35
1.48		 1.5
1.08
1.47
1.57		 1.25
1.39
1.75
0.856		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010025 C26:1DH Sphingomyelin842.7 (ions) -
-
-
0.163		 0.219
0.161
0.186
0.176		 0.153
0.168
0.174
0.146		 0.162
0.143
0.179
0.149		 0.137
0.134
0.179
0.14		 0.142
0.124
0.165
0.152		 0.199
0.131
0.176
0.167		 0.148
0.144
0.158
0.118		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP03010026 C26DH Sphingomyelin844.7 (ions) -
-
-
0.138		 0.17
0.135
0.141
0.121		 0.166
0.139
0.164
0.145		 0.164
0.192
0.145
0.137		 0.139
0.113
0.171
0.129		 0.108
0.105
0.167
0.143		 0.184
0.121
0.154
0.168		 0.125
0.129
0.162
0.099		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA28 C14DH GlcCer673.5 (ions) -
-
-
-		 0.008
-
-
-		 -
-
-
-		 -
-
-
0.076		 -
0.03
-
-		 -
0.007
0.028
-		 -
-
-
-		 -
-
-
0.06		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA04 C16DH GlcCer701.6 (ions) -
-
-
0.536		 0.397
0.309
0.537
0.428		 0.413
0.514
0.466
0.382		 0.415
0.338
0.623
0.31		 0.354
0.146
0.214
0.682		 0.485
0.409
0.369
0.344		 0.065
0.337
0.213
0.345		 0.515
1
0.166
0.206		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA29 C18:1DH GlcCer727.6 (ions) -
-
-
0.028		 0.012
0.08
0.033
0.037		 -
-
-
0.019		 -
-
-
-		 -
-
0.022
0.019		 0.051
0.01
0.028
0.05		 -
-
0.064
-		 0.049
-
0.122
-		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA19 C18DH GlcCer729.6 (ions) -
-
-
0.107		 0.255
0.011
0.042
0.045		 0.073
0.124
0
0.036		 0.246
-
0.3
-		 0.168
0.082
-
0.067		 0.03
0.072
0.16
-		 0.083
0.035
0.021
0.099		 -
0.059
0.174
-		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA20 C20DH GlcCer757.6 (ions) -
-
-
0.283		 0.087
0.213
0.229
0.067		 0.336
0.298
0.326
0.132		 0.283
0.324
0.266
0.02		 0.129
0.109
0.182
0.146		 0.574
0.488
0.499
0.271		 0.226
0.31
0.416
0.131		 0.219
-
0.028
0.075		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA21 C22DH GlcCer785.7 (ions) -
-
-
0.193		 0.203
0.38
0.197
0.298		 0.25
0.133
0.083
0.179		 0.468
0.368
0.1
-		 0.21
0.158
0.332
0.094		 0.518
-
0.119
0.372		 0.118
0.345
0.192
0.222		 0.435
0.469
0.194
0.161		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA22 C24:1DH GlcCer811.7 (ions) -
-
-
0.048		 0.41
0.223
0.437
0.339		 0.358
0.399
0.431
0.242		 0.236
0.326
0.332
0.495		 0.17
0.423
0.133
0.372		 0.538
0.382
0.487
0.204		 0.244
0.421
0.263
0.479		 0.954
0.317
0.242
0.147		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA23 C24DH GlcCer813.7 (ions) -
-
-
0.856		 0.622
0.116
-
0.016		 0.328
0.07
0.16
-		 -
0.297
0.078
0.119		 -
0.163
0.026
0.121		 0.286
0.158
0.149
0.708		 0.184
0.053
-
0.252		 0.369
0.443
0.184
0.013		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA24 C26:1DH GlcCer839.7 (ions) -
-
-
0.039		 0.031
0.039
0.035
0.054		 -
0.032
-
0.042		 -
-
0.014
0.045		 0.005
0.034
0.03
0.031		 0.046
0.033
0.078
0.034		 0.037
-
-
-		 0.038
-
-
-		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP0501AA25 C26DH GlcCer841.7 (ions) -
-
-
-		 -
-
0.032
-		 -
-
-
0.019		 -
0.748
-
-		 0.036
-
0.023
-		 -
-
-
-		 -
-
-
-		 0.066
-
-
0.028		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP01020001 Sphinganine301.3 (ions) -
-
-
0.065		 0.076
0.044
0.12
0.07		 0.086
0.044
0.131
0.075		 0.069
0.039
0.129
0.07		 0.074
0.05
0.111
0.098		 0.087
0.075
0.122
0.074		 0.095
0.116
0.065
0.082		 0.057
0.053
0.056
0.071		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP01050002 Sphinganine-P381.3 (ions) -
-
-
0.012		 0.015
0.011
0.011
0.01		 0.015
0.012
0.013
0.007		 0.015
0.012
0.016
0.015		 0.01
0.01
0.016
0.02		 0.011
0.014
0.021
0.007		 0.026
0.01
0.013
0.011		 0.013
0.012
0.018
0.018		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP01010001 Sphingosine299.3 (ions) -
-
-
0.761		 0.977
0.746
0.89
0.811		 0.932
0.729
0.957
0.833		 1.06
0.828
0.962
0.771		 1.05
0.933
0.88
0.84		 0.902
0.84
0.719
0.877		 0.84
0.74
0.486
0.993		 0.521
0.492
0.548
0.936		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
LMSP01050001 Sphingosine-P379.2 (ions) -
-
-
0.008		 0.011
0.01
0.009
0.009		 0.015
0.011
0.009
0.006		 0.016
0.015
0.012
0.009		 0.017
0.014
0.011
0.008		 0.021
0.013
0.008
0.007		 0.025
0.014
0.012
0.01		 0.016
0.013
0.014
0.014		 pmol/ug DNA
Legend: :Ctrl  :Kdo2-lipid A  :ATP  :ATP+Kdo2-lipid A
- DNA- -
-
-
10.6		 9.6
9.86
10.1
9.53		 11
10.9
9.3
11.2		 7.65
9.19
9.94
9.52		 7.47
7.96
8.5
11.1		 6.3
9.33
12.5
11.5		 8.41
9.99
8.94
11.4		 7.71
10.9
12.7
11.9		 ug/sample