Structure Database (LMSD)

Common Name
Cannabidiolic acid
Systematic Name
Synonyms
LM ID
LMPK13120003
Formula
Exact Mass
Calculate m/z
358.21441
Status
Curated


Classification

Biological Context

Cannabidiolic acid (CRM) is a certified reference material categorized as a phytocannabinoid.1,2 Cannabidiolic acid has anxiolytic-like and antinociceptive activities in mice.2,3 Cannabidiolic acid (CRM) is registered as a Canada Test Kit. This product is intended for research and forensic applications.

This information has been provided by Cayman Chemical

References

1. Vigli, D., Cosentino, L., Pellas, M., et al. Chronic treatment with cannabidiolic scid (CBDA) reduces thermal pain sensitivity in male mice and rescues the hyperalgesia in a mouse model of Rett syndrome. Neuroscience 453, 113-123 (2021).
3. Taura, F., Morimoto, S., and Shoyama, Y. Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid. J. Biol. Chem. 271(29), 17411-17416 (1996).

References

Taxonomy Information

Curated from
NCBI taxonomy class
Reference
Cannabis sativa (#3483)
Magnoliopsida (#3398)
Hashish. IV. The isolation and structure of cannabinolic cannabidiolic and cannabigerolic acids.,
Tetrahedron, 1965
Pubmed ID: 5879350

String Representations

InChiKey (Click to copy)
WVOLTBSCXRRQFR-DLBZAZTESA-N
InChi (Click to copy)
InChI=1S/C22H30O4/c1-5-6-7-8-15-12-18(23)20(21(24)19(15)22(25)26)17-11-14(4)9-10-16(17)13(2)3/h11-12,16-17,23-24H,2,5-10H2,1,3-4H3,(H,25,26)/t16-,17+/m0/s1
SMILES (Click to copy)
[C@]1([H])([C@H](C(=C)C)CCC(C)=C1)C1C(O)=C(C(O)=O)C(CCCCC)=CC=1O

Other Databases

KEGG ID
CHEBI ID
PubChem CID
Cayman ID
GuidePharm ID

Calculated Physicochemical Properties

Heavy Atoms 26
Rings 2
Aromatic Rings 1
Rotatable Bonds 7
Van der Waals Molecular Volume 372.86
Topological Polar Surface Area 77.76
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
logP 5.54
Molar Refractivity 104.00

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Created at
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Updated at
31st Jul 2024