Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Caffeine metabolism (mmu00232)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
Cyp1a2	KLA  ATP  ATP+KLA	NM_009993	cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2), mRNA [NM_009993]	KLA	1.01	.99	.98	1.02	.97	.97	1.00
				ATP	1.01	.98	1.03	1.01	1.04	1.02	1.04
				KLA/ATP	.99	1.00	1.05	1.03	.98	.97	.99
Cyp2a12	KLA  ATP  ATP+KLA	NM_133657	cytochrome P450, family 2, subfamily a, polypeptide 12 (Cyp2a12), mRNA [NM_133657]	KLA	1.03	1.08	1.00	.98	1.00	1.03	1.03
				ATP	1.01	.98	1.03	1.08	1.02	.99	1.01
				KLA/ATP	.97	1.01	.97	1.06	1.03	1.03	.99
Cyp2a4	KLA  ATP  ATP+KLA	NM_009997	cytochrome P450, family 2, subfamily a, polypeptide 4 (Cyp2a4), mRNA [NM_009997]	KLA	1.02	.99	1.00	1.00	.98	1.04	1.01
				ATP	1.01	1.00	1.01	1.03	.99	1.01	.99
				KLA/ATP	1.03	1.03	1.01	1.04	.98	1.03	1.01
Cyp2a5	KLA  ATP  ATP+KLA	NM_007812	cytochrome P450, family 2, subfamily a, polypeptide 5 (Cyp2a5), mRNA [NM_007812]	KLA	1.04	.95	.95	1.02	1.01	.94	1.06
				ATP	1.03	.95	1.05	1.08	.99	.97	1.03
				KLA/ATP	1.01	1.06	.92	1.08	1.05	1.01	1.01
Mm.38984 8	KLA  ATP  ATP+KLA	116268117	Unknown	KLA	.98	1.02	1.01	1.05	.97	.97	.96
				ATP	.95	1.01	1.04	1.14	.99	.91	1.01
				KLA/ATP	1.08	.92	1.02	1.00	.97	.97	.99
Nat1	KLA  ATP  ATP+KLA	NM_008673	N-acetyltransferase 1 (arylamine N-acetyltransferase) (Nat1), mRNA [NM_008673]	KLA	.97	.98	1.00	.94	1.01	.95	1.02
				ATP	1.03	.96	1.01	1.04	1.03	.99	1.01
				KLA/ATP	1.03	.98	.94	1.00	.99	1.05	.86
Nat2	KLA  ATP  ATP+KLA	NM_010874	N-acetyltransferase 2 (arylamine N-acetyltransferase) (Nat2), mRNA [NM_010874]	KLA	3.59	3.77	3.60	2.69	2.11	2.24	1.44
				ATP	.96	.91	.74	.42	.39	1.32	1.45
				KLA/ATP	3.43	3.33	2.84	1.60	.89	2.12	2.09
Nat3	KLA  ATP  ATP+KLA	NM_008674	N-acetyltransferase 3 (Nat3), mRNA [NM_008674]	KLA	1.00	1.06	1.05	1.02	1.07	1.05	1.11
				ATP	.98	.99	1.05	1.05	1.04	1.02	1.11
				KLA/ATP	1.03	.95	.96	1.03	.96	1.04	.99
Uox	KLA  ATP  ATP+KLA	NM_009474	urate oxidase (Uox), mRNA [NM_009474]	KLA	.98	.99	1.00	1.00	1.02	1.02	1.01
				ATP	.99	.98	.98	1.05	1.02	1.01	1.05
				KLA/ATP	1.02	1.00	1.02	1.04	1.02	.99	1.02
Xdh	KLA  ATP  ATP+KLA	NM_011723	xanthine dehydrogenase (Xdh), mRNA [NM_011723]	KLA	1.82	1.90	2.33	2.06	2.49	2.56	1.77
				ATP	1.02	1.15	.98	1.10	1.06	1.02	1.42
				KLA/ATP	2.00	2.00	2.02	2.11	1.27	1.56	1.92