Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Glycosphingolipid biosynthesis - globo series (mmu00603)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
B3galnt1	KLA  ATP  ATP+KLA	NM_020026	UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 (B3galnt1), mRNA [NM_020026]	KLA	.64	.60	.62	.55	.47	.61	.93
				ATP	1.00	.94	1.10	.85	.52	.44	.68
				KLA/ATP	.61	.62	.65	.53	.49	.49	.71
B3galt5	KLA  ATP  ATP+KLA	NM_033149	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (B3galt5), transcript variant 1, mRNA [NM_033149]	KLA	.78	.84	.81	.88	.86	.90	.80
				ATP	1.03	.88	1.08	.91	.87	.73	.83
				KLA/ATP	.85	.80	.85	.85	.96	.89	.72
Fut1	KLA  ATP  ATP+KLA	NM_008051	fucosyltransferase 1 (Fut1), mRNA [NM_008051]	KLA	.94	1.00	.99	1.00	.97	.98	1.00
				ATP	1.05	.97	1.00	.99	1.04	1.00	.98
				KLA/ATP	1.01	1.02	.99	1.02	1.06	1.04	.99
Fut2	KLA  ATP  ATP+KLA	NM_018876	fucosyltransferase 2 (Fut2), mRNA [NM_018876]	KLA	.97	.97	1.01	1.02	.98	1.04	1.01
				ATP	1.05	1.00	.97	.99	1.05	1.02	1.07
				KLA/ATP	1.00	.99	1.03	1.00	1.03	.99	1.07
Fut9	KLA  ATP  ATP+KLA	NM_010243	fucosyltransferase 9 (Fut9), mRNA [NM_010243]	KLA	.99	.99	1.02	1.02	1.02	1.02	.98
				ATP	.99	1.01	.99	.98	1.01	.99	1.04
				KLA/ATP	1.00	.97	1.06	1.00	.96	1.01	.96
Gbgt1	KLA  ATP  ATP+KLA	NM_139197	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (Gbgt1), mRNA [NM_139197]	KLA	1.13	1.21	1.26	1.34	1.62	1.88	2.04
				ATP	1.00	1.02	1.02	1.04	.93	.92	1.07
				KLA/ATP	1.14	1.22	1.11	1.13	.98	1.08	1.62
Gla	KLA  ATP  ATP+KLA	NM_013463	galactosidase, alpha (Gla), mRNA [NM_013463]	KLA	.91	.95	1.02	.93	1.02	1.35	1.99
				ATP	1.06	1.22	1.08	1.49	1.31	1.44	3.32
				KLA/ATP	1.01	1.05	.89	1.54	1.26	1.98	5.13
Gla	KLA  ATP  ATP+KLA	U34071	alpha-galactosidase A mRNA, complete cds. [U34071]	KLA	.99	.99	1.18	1.28	1.30	1.59	1.66
				ATP	1.12	1.20	1.32	1.74	1.93	1.44	1.50
				KLA/ATP	1.12	1.24	1.28	1.98	2.55	2.85	2.82
Hexa	KLA  ATP  ATP+KLA	NM_010421	hexosaminidase A (Hexa), mRNA [NM_010421]	KLA	.74	.76	.70	.63	.57	.52	.51
				ATP	.98	1.04	.82	.81	.68	.52	.64
				KLA/ATP	.76	.78	.63	.60	.48	.37	.31
Hexb	KLA  ATP  ATP+KLA	NM_010422	hexosaminidase B (Hexb), mRNA [NM_010422]	KLA	.82	.90	.81	.70	.64	.64	.71
				ATP	.95	1.03	1.11	.83	.72	.58	.63
				KLA/ATP	.80	.83	.77	.68	.53	.45	.50
Mm.32380 5	KLA  ATP  ATP+KLA	195546943	Unknown	KLA	1.01	.94	1.03	1.09	1.03	1.06	.97
				ATP	.98	.98	1.06	.98	1.00	.95	1.17
				KLA/ATP	1.05	1.06	1.05	1.08	1.05	1.09	1.21
Naga	KLA  ATP  ATP+KLA	NM_008669	N-acetyl galactosaminidase, alpha (Naga), mRNA [NM_008669]	KLA	1.05	1.04	1.08	1.06	.99	.94	1.09
				ATP	1.02	1.20	.96	1.63	1.00	.72	1.08
				KLA/ATP	1.09	1.19	.88	1.54	.81	.77	1.20
Sec1	KLA  ATP  ATP+KLA	NM_019934	secretory blood group 1 (Sec1), mRNA [NM_019934]	KLA	1.01	1.02	.90	1.00	1.02	1.02	1.05
				ATP	.99	1.00	.98	1.04	1.00	1.02	1.03
				KLA/ATP	1.02	1.04	1.01	.97	.97	1.01	1.13
St3gal1	KLA  ATP  ATP+KLA	NM_009177	ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (St3gal1), mRNA [NM_009177]	KLA	9.07	8.10	8.07	8.61	6.32	6.17	4.65
				ATP	.97	.87	1.27	4.14	10.38	21.66	8.10
				KLA/ATP	8.21	8.67	10.15	8.82	11.00	12.94	21.26
St3gal2	KLA  ATP  ATP+KLA	NM_009179	ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (St3gal2), mRNA [NM_009179]	KLA	.70	.72	.72	.65	.58	.53	.65
				ATP	.96	.96	.88	.76	.61	.60	1.17
				KLA/ATP	.75	.71	.67	.63	.50	.47	.68
St8sia1	KLA  ATP  ATP+KLA	NM_011374	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (St8sia1), mRNA [NM_011374]	KLA	.96	.94	.94	.99	.94	.93	.91
				ATP	1.04	.99	1.05	1.02	.95	.93	.86
				KLA/ATP	.93	.90	.98	.95	.94	.90	.87