Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

Search by fold change ratio | Search by KEGG pathway | Search by LIPID MAPS lipid pathway

Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: ABC transporters (mmu02010)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Abca1
KLA  ATP  ATP+KLA
 NM_013454 ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1), mRNA [NM_013454] KLA .69 .60 .65 .69 1.48 1.80 1.46
ATP 1.23 1.10 .81 1.24 2.92 5.72 1.45
KLA/ATP .77 .62 .54 1.00 2.34 4.04 2.36
Abca12
KLA  ATP  ATP+KLA
 AK076440 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4832428G11 product:ATP-BINDING CASSETTE TRANSPORTER FAMILY A MEMBER 12 homolog [Homo sapiens], full insert sequence. [AK076440] KLA .90 1.00 .97 1.03 1.00 .98 1.05
ATP .98 1.02 1.02 1.06 1.00 .97 1.00
KLA/ATP .98 1.02 1.01 .96 .92 .92 1.01
Abca12
KLA  ATP  ATP+KLA
 XM_001002308 gb|PREDICTED: Mus musculus ATP-binding cassette, sub-family A (ABC1), member 12, transcript variant 3 (Abca12), mRNA [XM_001002308] KLA .97 .96 1.03 1.02 1.00 1.04 .99
ATP .99 .98 1.01 .99 1.00 1.04 .96
KLA/ATP .99 1.01 .93 .98 1.01 1.00 1.01
Abca13
KLA  ATP  ATP+KLA
 AK036546 adult male bone cDNA, RIKEN full-length enriched library, clone:9830132L24 product:hypothetical protein, full insert sequence. [AK036546] KLA 1.00 1.06 .96 .96 1.05 .93 1.08
ATP 1.02 1.07 1.02 1.06 1.02 .99 1.00
KLA/ATP 1.01 1.00 1.01 .99 .99 1.05 .98
Abca13
KLA  ATP  ATP+KLA
 NM_178259 ATP-binding cassette, sub-family A (ABC1), member 13 (Abca13), mRNA [NM_178259] KLA 1.07 .98 1.06 .99 1.02 1.02 1.00
ATP .98 1.02 .99 .90 1.02 .97 1.03
KLA/ATP .99 1.06 1.02 1.00 .99 1.00 1.05
Abca17
KLA  ATP  ATP+KLA
 NM_001031621 ATP-binding cassette, sub-family A (ABC1), member 17 (Abca17), mRNA [NM_001031621] KLA 1.23 1.07 1.30 1.31 1.35 1.17 1.05
ATP 1.04 1.02 1.04 .93 .89 .92 .94
KLA/ATP 1.12 1.12 1.07 .95 .96 .94 .94
Abca2
KLA  ATP  ATP+KLA
 NM_007379 ATP-binding cassette, sub-family A (ABC1), member 2 (Abca2), mRNA [NM_007379] KLA .78 .80 .77 .59 .57 .44 .54
ATP 1.11 1.27 .82 1.16 .74 .49 .69
KLA/ATP .94 .92 .60 .73 .53 .42 .43
Abca3
KLA  ATP  ATP+KLA
 AK089316 B6-derived CD11 +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F730004H09 product:ATP-binding cassette, sub-family A (ABC1), member 3, full insert sequence. [AK089316] KLA 1.03 .98 1.06 1.00 .98 1.01 1.05
ATP .97 .94 1.05 1.00 .96 1.01 .99
KLA/ATP 1.06 1.04 .98 1.02 .92 .99 .94
Abca3
KLA  ATP  ATP+KLA
 NM_013855 ATP-binding cassette, sub-family A (ABC1), member 3 (Abca3), transcript variant 1, mRNA [NM_013855] KLA .97 .98 .99 .95 .97 .97 1.03
ATP .98 .89 .74 .70 .63 .70 .93
KLA/ATP .96 .89 .80 .77 .73 .72 .96
Abca4
KLA  ATP  ATP+KLA
 NM_007378 ATP-binding cassette, sub-family A (ABC1), member 4 (Abca4), mRNA [NM_007378] KLA 1.02 1.06 1.00 .99 1.04 .99 1.03
ATP .98 1.03 1.01 .99 .97 1.06 1.03
KLA/ATP 1.02 .99 1.01 1.03 1.03 .99 1.08
Abca5
KLA  ATP  ATP+KLA
 AK035955 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630020L03 product:weakly similar to ATP-BINDING CASSETTE PROTEIN [Homo sapiens], full insert sequence. [AK035955] KLA .98 1.00 1.05 1.00 .94 1.03 .95
ATP 1.00 1.01 .94 1.11 .99 1.09 1.03
KLA/ATP 1.02 1.02 .80 .99 .97 1.02 .99
Abca5
KLA  ATP  ATP+KLA
 NM_147219 ATP-binding cassette, sub-family A (ABC1), member 5 (Abca5), mRNA [NM_147219] KLA .99 .98 .96 .89 .86 .87 .93
ATP .97 1.06 1.01 .99 1.26 .99 1.06
KLA/ATP .99 .99 .96 .90 .90 .92 1.05
Abca6
KLA  ATP  ATP+KLA
 AK040652 adult male aorta and vein cDNA, RIKEN full-length enriched library, clone:A530006M05 product:hypothetical protein, full insert sequence. [AK040652] KLA .75 .75 .85 .83 .77 .75 .63
ATP 1.02 .98 .97 .98 .88 .76 .62
KLA/ATP .72 .77 .93 .78 .79 .71 .64
Abca6
KLA  ATP  ATP+KLA
 NM_147218 ATP-binding cassette, sub-family A (ABC1), member 6 (Abca6), mRNA [NM_147218] KLA .98 .99 .90 .95 .99 .87 .79
ATP .91 .94 1.11 1.01 .99 .87 .75
KLA/ATP 1.01 .90 .98 1.02 .90 .85 .70
Abca7
KLA  ATP  ATP+KLA
 NM_013850 ATP-binding cassette, sub-family A (ABC1), member 7 (Abca7), mRNA [NM_013850] KLA 1.14 1.06 1.05 1.41 1.41 1.17 1.03
ATP 1.03 .99 1.05 .89 .97 1.56 1.09
KLA/ATP 1.15 1.06 1.28 1.05 1.31 1.25 1.20
Abca8a
KLA  ATP  ATP+KLA
 NM_153145 ATP-binding cassette, sub-family A (ABC1), member 8a (Abca8a), mRNA [NM_153145] KLA 1.01 .99 .95 1.03 1.00 .99 .96
ATP .98 1.08 1.01 .95 .97 .98 .94
KLA/ATP 1.02 .97 .96 .93 .91 .94 1.16
Abca8b
KLA  ATP  ATP+KLA
 NM_013851 ATP-binding cassette, sub-family A (ABC1), member 8b (Abca8b), mRNA [NM_013851] KLA .92 .90 .95 .84 .80 .81 .84
ATP 1.04 1.07 1.07 1.16 1.41 .99 .92
KLA/ATP .96 .90 .86 .92 .93 1.00 1.06
Abca9
KLA  ATP  ATP+KLA
 NM_147220 ATP-binding cassette, sub-family A (ABC1), member 9 (Abca9), mRNA [NM_147220] KLA .84 .80 .82 .81 .77 .65 .62
ATP 1.05 1.05 .99 .93 .78 .62 .47
KLA/ATP .79 .76 .82 .88 .71 .59 .46
Abcb10
KLA  ATP  ATP+KLA
 AK011569 10 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2610027L15 product:ATP-binding cassette, sub-family B (MDR/TAP), member 10, full insert sequence. [AK011569] KLA .90 .89 .75 .75 .80 .78 .88
ATP .81 .70 .69 .70 .82 .95 1.02
KLA/ATP .79 .71 .73 .69 .89 .83 .73
Abcb10
KLA  ATP  ATP+KLA
 NM_019552 ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), nuclear gene encoding mitochondrial protein, mRNA [NM_019552] KLA 1.10 1.16 1.22 1.02 .72 .52 .73
ATP 1.01 1.03 1.01 .92 .63 .74 1.13
KLA/ATP 1.23 1.26 1.06 1.03 .77 .62 .57
Abcb11
KLA  ATP  ATP+KLA
 NM_021022 ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11), mRNA [NM_021022] KLA 1.01 .93 1.04 .97 .97 1.00 .97
ATP 1.00 .94 .97 1.05 .94 .92 .95
KLA/ATP 1.04 .96 1.03 .95 .95 1.01 .99
Abcb1a
KLA  ATP  ATP+KLA
 NM_011076 ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a), mRNA [NM_011076] KLA 1.24 1.32 1.51 1.43 1.41 1.20 .95
ATP 1.00 1.02 1.03 1.04 1.10 1.47 1.06
KLA/ATP 1.26 1.26 1.14 1.16 1.19 1.39 1.13
Abcb1b
KLA  ATP  ATP+KLA
 NM_011075 ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), mRNA [NM_011075] KLA 1.67 1.61 1.50 1.08 .67 .40 .31
ATP 1.09 1.32 1.19 1.68 1.23 .95 .34
KLA/ATP 1.63 1.89 1.85 2.17 1.07 .58 .27
Abcb4
KLA  ATP  ATP+KLA
 NM_008830 ATP-binding cassette, sub-family B (MDR/TAP), member 4 (Abcb4), mRNA [NM_008830] KLA .81 .82 .69 .53 .35 .24 .19
ATP .98 1.03 1.08 1.05 .91 .74 .65
KLA/ATP .82 .87 .83 .82 .68 .39 .28
Abcb5
KLA  ATP  ATP+KLA
 XM_001002680 gb|PREDICTED: Mus musculus ATP-binding cassette, sub-family B (MDR [XM_001002680] KLA 1.05 1.05 .99 1.01 .99 1.03 1.04
ATP 1.02 1.02 1.03 .98 1.04 1.06 1.01
KLA/ATP .93 .99 .99 1.01 1.03 1.02 1.01
Abcb6
KLA  ATP  ATP+KLA
 NM_023732 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Abcb6), nuclear gene encoding mitochondrial protein, mRNA [NM_023732] KLA .80 .83 .71 .66 .53 .49 .58
ATP .86 .90 .87 .77 .89 1.25 .83
KLA/ATP .79 .79 .69 .63 .58 .58 .57
Abcb7
KLA  ATP  ATP+KLA
 NM_009592 ATP-binding cassette, sub-family B (MDR/TAP), member 7 (Abcb7), nuclear gene encoding mitochondrial protein, mRNA [NM_009592] KLA 1.02 1.06 .90 .87 .68 .70 1.07
ATP 1.04 1.17 1.18 1.22 .95 .73 .98
KLA/ATP 1.10 1.07 .95 1.00 .74 .66 .97
Abcb8
KLA  ATP  ATP+KLA
 AK014688 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4833412N02 product:ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 8, MITOCHONDRIAL PRECURSOR (MITOCHONDRIAL ATP-BINDING CASSETTE 1) (M-ABC1), full insert sequence. [AK014688] KLA 1.01 1.00 1.01 1.06 1.02 .98 .99
ATP 1.02 1.00 .92 1.04 .99 1.05 1.04
KLA/ATP 1.06 1.06 1.02 .96 1.00 .99 1.04
Abcb8
KLA  ATP  ATP+KLA
 NM_029020 ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), nuclear gene encoding mitochondrial protein, mRNA [NM_029020] KLA .68 .77 .72 .63 .58 .51 .82
ATP 1.08 1.15 1.04 1.12 .81 .44 .83
KLA/ATP .76 .81 .71 .73 .57 .54 .57
Abcb9
KLA  ATP  ATP+KLA
 NM_019875 ATP-binding cassette, sub-family B (MDR/TAP), member 9 (Abcb9), mRNA [NM_019875] KLA .74 .72 .72 .95 .90 .86 .78
ATP 1.05 .90 1.25 .96 1.00 .84 .66
KLA/ATP .80 .76 1.02 .73 .90 .80 .93
Abcc1
KLA  ATP  ATP+KLA
 NM_008576 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA [NM_008576] KLA 1.13 1.15 .99 .80 .68 .47 .78
ATP .99 1.05 1.05 .89 1.40 1.96 1.02
KLA/ATP 1.17 1.22 1.01 .78 .64 .80 1.07
Abcc10
KLA  ATP  ATP+KLA
 NM_145140 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (Abcc10), transcript variant mrp7A, mRNA [NM_145140] KLA 1.05 .96 .88 .90 .99 1.04 .99
ATP 1.01 1.12 1.00 .89 .80 .95 1.05
KLA/ATP .93 .91 .96 .96 .84 .80 1.06
Abcc12
KLA  ATP  ATP+KLA
 NM_172912 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 (Abcc12), mRNA [NM_172912] KLA 1.03 1.05 1.01 1.02 1.04 1.02 1.02
ATP 1.02 1.03 .96 1.03 1.00 1.03 .98
KLA/ATP 1.04 .98 1.00 1.03 1.02 1.02 1.04
Abcc2
KLA  ATP  ATP+KLA
 NM_013806 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), mRNA [NM_013806] KLA .94 .94 .91 .92 .92 .93 .88
ATP 1.01 1.00 1.05 .94 .95 1.22 1.18
KLA/ATP .98 .94 .92 .93 1.01 1.47 1.43
Abcc3
KLA  ATP  ATP+KLA
 NM_029600 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (Abcc3), mRNA [NM_029600] KLA .79 .78 .76 .67 .54 .53 .79
ATP .93 .99 1.01 .89 .69 .55 1.11
KLA/ATP .83 .83 .78 .67 .51 .47 .70
Abcc4
KLA  ATP  ATP+KLA
 NM_001033336 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), mRNA [NM_001033336] KLA 1.11 1.06 1.18 1.10 1.17 1.12 .82
ATP 1.13 .92 1.28 .92 .75 1.55 .40
KLA/ATP 1.09 1.11 1.42 .93 .65 .64 .40
Abcc5
KLA  ATP  ATP+KLA
 NM_013790 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), transcript variant 1, mRNA [NM_013790] KLA 1.47 1.44 1.62 1.73 2.96 2.48 2.94
ATP 1.00 1.09 1.10 1.00 3.15 4.25 .70
KLA/ATP 1.51 1.73 1.59 1.39 2.60 3.97 2.55
Abcc5
KLA  ATP  ATP+KLA
 NM_176839 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), transcript variant 2, mRNA [NM_176839] KLA 1.52 1.44 1.57 1.74 1.98 2.34 2.31
ATP .81 .77 .92 .94 1.04 2.87 1.61
KLA/ATP 1.23 1.23 1.39 1.41 1.24 2.07 3.84
Abcc6
KLA  ATP  ATP+KLA
 NM_018795 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6), mRNA [NM_018795] KLA 1.05 1.09 1.12 1.04 1.01 1.09 1.08
ATP 1.03 1.03 1.06 1.18 1.04 1.07 1.05
KLA/ATP 1.02 1.00 1.08 1.20 1.14 1.10 .96
Abcc8
KLA  ATP  ATP+KLA
 NM_011510 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), mRNA [NM_011510] KLA .98 1.00 1.03 .99 .96 .99 .98
ATP 1.00 .97 1.03 1.00 .98 .99 1.06
KLA/ATP 1.00 1.01 1.01 1.01 .94 .99 .99
Abcc9
KLA  ATP  ATP+KLA
 NM_021041 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (Abcc9), transcript variant 2, mRNA [NM_021041] KLA 1.00 .99 1.02 .97 1.01 .97 1.06
ATP .97 .97 1.01 .99 1.04 .99 1.02
KLA/ATP 1.02 1.01 1.02 .99 1.04 .99 1.01
Abcd1
KLA  ATP  ATP+KLA
 AF213385 ATP-binding cassette protein (Abcd1) mRNA, partial cds. [AF213385] KLA 1.01 1.10 1.02 .95 1.20 1.49 1.29
ATP 1.08 1.23 .96 1.22 .79 .70 1.15
KLA/ATP 1.13 1.16 .86 1.15 .85 .84 1.39
Abcd1
KLA  ATP  ATP+KLA
 NM_007435 ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), mRNA [NM_007435] KLA 1.00 .97 1.03 1.08 1.33 1.52 1.38
ATP 1.17 1.39 1.00 1.50 .86 .61 1.20
KLA/ATP 1.23 1.20 .90 1.17 .84 .84 1.63
Abcd2
KLA  ATP  ATP+KLA
 NM_011994 ATP-binding cassette, sub-family D (ALD), member 2 (Abcd2), mRNA [NM_011994] KLA .89 .87 .90 .90 .83 .74 .74
ATP 1.06 1.01 1.17 .89 .77 .80 .72
KLA/ATP .84 .84 .88 .88 .84 .74 .71
Abcd3
KLA  ATP  ATP+KLA
 NM_008991 ATP-binding cassette, sub-family D (ALD), member 3 (Abcd3), mRNA [NM_008991] KLA .90 .94 .89 .85 .75 .80 1.16
ATP 1.01 1.08 1.07 1.07 .92 .77 1.07
KLA/ATP .92 .95 .86 .93 .89 .84 .85
Abcd4
KLA  ATP  ATP+KLA
 NM_008992 ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4), mRNA [NM_008992] KLA .50 .49 .50 .47 .50 .61 1.14
ATP .97 1.10 .98 .95 .68 .45 1.72
KLA/ATP .49 .52 .47 .50 .50 .51 1.11
Abcg1
KLA  ATP  ATP+KLA
 NM_009593 ATP-binding cassette, sub-family G (WHITE), member 1 (Abcg1), mRNA [NM_009593] KLA 1.16 1.22 1.30 1.75 1.97 2.05 1.49
ATP .94 .89 .79 .70 .75 1.08 1.70
KLA/ATP .96 1.13 1.13 .95 2.00 2.64 2.90
Abcg2
KLA  ATP  ATP+KLA
 NM_011920 ATP-binding cassette, sub-family G (WHITE), member 2 (Abcg2), mRNA [NM_011920] KLA .80 .82 .76 .68 .58 .52 .62
ATP .95 .94 .94 .91 .68 .39 .38
KLA/ATP .83 .81 .72 .73 .54 .39 .27
Abcg3
KLA  ATP  ATP+KLA
 NM_030239 ATP-binding cassette, sub-family G (WHITE), member 3 (Abcg3), mRNA [NM_030239] KLA .70 .68 .65 .66 .61 .49 .34
ATP 1.00 1.05 1.02 .97 .67 .53 .49
KLA/ATP .66 .70 .70 .73 .64 .51 .31
Abcg4
KLA  ATP  ATP+KLA
 NM_138955 ATP-binding cassette, sub-family G (WHITE), member 4 (Abcg4), mRNA [NM_138955] KLA 1.15 1.21 1.19 1.14 1.20 1.32 1.05
ATP .95 .98 .98 1.11 1.13 1.08 .99
KLA/ATP 1.19 1.38 1.40 1.59 1.71 1.29 1.13
Abcg5
KLA  ATP  ATP+KLA
 NM_031884 ATP-binding cassette, sub-family G (WHITE), member 5 (Abcg5), mRNA [NM_031884] KLA 1.03 1.03 1.03 1.03 .98 .94 .99
ATP 1.14 .98 .96 .94 1.04 .99 .96
KLA/ATP .98 1.00 .99 .92 .91 1.04 1.03
Abcg8
KLA  ATP  ATP+KLA
 NM_026180 ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8), mRNA [NM_026180] KLA 1.01 1.03 1.03 .99 1.02 1.06 .98
ATP .99 1.00 1.01 1.00 .97 1.04 1.05
KLA/ATP .98 .94 1.06 1.01 .99 .98 1.08
Cftr
KLA  ATP  ATP+KLA
 NM_021050 cystic fibrosis transmembrane conductance regulator homolog (Cftr), mRNA [NM_021050] KLA 1.00 1.01 1.00 1.00 1.01 1.01 1.03
ATP 1.01 .99 .99 1.02 .99 .99 1.01
KLA/ATP 1.03 1.01 .99 .99 .98 1.02 1.01
Mm.20735
4
KLA  ATP  ATP+KLA
 153791546 Unknown KLA 2.55 2.91 3.13 3.94 2.81 2.17 .88
ATP .94 .94 1.06 1.06 1.56 3.88 1.30
KLA/ATP 2.25 2.53 2.66 1.89 2.08 3.58 1.89
Mm.27737
6
KLA  ATP  ATP+KLA
 90568037 Unknown KLA .66 .59 .62 .83 1.44 1.94 1.41
ATP .95 .79 .79 1.03 2.52 6.30 1.26
KLA/ATP .52 .48 .55 .90 2.69 4.57 1.99
Mm.32884
2
KLA  ATP  ATP+KLA
 157057149 Unknown KLA .97 1.03 .99 1.01 1.02 .99 1.10
ATP 1.00 .94 1.05 1.05 1.00 1.05 .99
KLA/ATP 1.04 .89 1.03 .96 1.01 1.05 1.08
Mm.38966
3
KLA  ATP  ATP+KLA
 66932958 Unknown KLA .54 .43 .50 .50 .38 .31 .15
ATP .89 .75 1.50 .97 .68 .33 .33
KLA/ATP .44 .46 .73 .56 .60 .30 .15
Mm.40537
KLA  ATP  ATP+KLA
 142358785 Unknown KLA 1.04 1.06 1.08 1.02 1.04 1.10 .93
ATP .87 .87 1.14 .90 .72 1.19 .52
KLA/ATP .96 1.04 1.15 .88 .77 .67 .47
Tap1
KLA  ATP  ATP+KLA
 NM_013683 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), mRNA [NM_013683] KLA 7.60 7.62 9.05 9.01 9.36 8.57 4.96
ATP 1.00 1.07 .96 1.13 .74 2.83 2.43
KLA/ATP 7.99 8.80 8.37 9.52 7.44 8.61 9.95
Tap2
KLA  ATP  ATP+KLA
 NM_011530 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2), mRNA [NM_011530] KLA 4.36 4.80 4.71 5.53 4.94 5.09 2.85
ATP .93 1.12 .97 1.20 1.38 2.30 2.20
KLA/ATP 4.15 5.22 6.03 6.07 5.60 5.42 6.52