Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: NF-kappa B signaling pathway (mmu04064)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Atm
KLA  ATP  ATP+KLA
 NM_007499 ataxia telangiectasia mutated homolog (human) (Atm), mRNA [NM_007499] KLA 1.86 1.97 2.17 1.67 1.20 .86 .79
ATP 1.09 1.17 1.01 .97 .61 .63 .69
KLA/ATP 2.11 2.24 1.55 1.46 .85 .75 .59
Bcl10
KLA  ATP  ATP+KLA
 AK080820 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230313B18 product:unclassifiable, full insert sequence [AK080820] KLA 1.44 1.52 1.23 1.38 1.54 1.25 1.08
ATP 1.31 1.35 1.59 1.40 3.05 2.29 .90
KLA/ATP 1.58 2.14 1.93 1.47 2.94 1.95 1.33
Bcl10
KLA  ATP  ATP+KLA
 NM_009740 B-cell leukemia/lymphoma 10 (Bcl10), mRNA [NM_009740] KLA 1.63 1.57 1.42 1.42 1.52 1.04 1.14
ATP 1.10 1.12 1.04 1.06 1.97 2.63 1.15
KLA/ATP 1.40 1.58 1.36 1.27 1.54 1.87 1.51
Bcl2
KLA  ATP  ATP+KLA
 NM_009741 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 1, mRNA [NM_009741] KLA .30 .26 .25 .25 .34 .38 .26
ATP .97 .89 1.50 1.04 .99 .29 .52
KLA/ATP .28 .26 .40 .33 .62 .29 .12
Bcl2
KLA  ATP  ATP+KLA
 NM_177410 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 2, mRNA [NM_177410] KLA .33 .33 .37 .42 .49 .46 .39
ATP 1.07 1.12 1.22 1.56 1.00 .38 .76
KLA/ATP .35 .34 .54 .89 .76 .36 .23
Bcl2a1b
KLA  ATP  ATP+KLA
 NM_007534 B-cell leukemia/lymphoma 2 related protein A1b (Bcl2a1b), mRNA [NM_007534] KLA 34.11 34.56 37.57 36.91 28.13 17.63 10.35
ATP 1.02 1.06 1.87 3.05 8.81 14.40 6.63
KLA/ATP 34.55 35.44 49.51 38.70 36.65 17.92 12.39
Bcl2a1c
KLA  ATP  ATP+KLA
 NM_007535 B-cell leukemia/lymphoma 2 related protein A1c (Bcl2a1c), mRNA [NM_007535] KLA 33.96 35.89 36.34 38.52 29.20 19.48 11.43
ATP 1.01 1.08 1.84 2.98 8.29 13.22 6.74
KLA/ATP 30.56 34.60 50.13 43.72 35.49 19.36 15.41
Bcl2l1
KLA  ATP  ATP+KLA
 NM_009743 Bcl2-like 1 (Bcl2l1), nuclear gene encoding mitochondrial protein, mRNA [NM_009743] KLA .99 1.02 1.10 1.16 1.27 .97 1.05
ATP 1.18 1.42 .81 1.26 1.51 .71 1.67
KLA/ATP 1.21 1.30 .66 1.15 1.31 1.17 1.59
Birc2
KLA  ATP  ATP+KLA
 NM_007465 baculoviral IAP repeat-containing 2 (Birc2), mRNA [NM_007465] KLA 4.63 4.59 3.77 2.79 2.32 2.07 1.84
ATP .95 .88 .84 .92 .76 1.34 1.28
KLA/ATP 4.70 4.93 4.13 2.60 1.34 1.60 2.31
Birc3
KLA  ATP  ATP+KLA
 BC011338 baculoviral IAP repeat-containing 3, mRNA (cDNA clone MGC:18386 IMAGE:3661563), complete cds [BC011338] KLA 5.48 5.46 4.94 4.16 4.91 3.36 3.74
ATP 1.05 1.08 4.21 4.28 2.59 2.55 1.57
KLA/ATP 6.78 8.91 11.01 4.87 2.28 2.12 3.66
Birc3
KLA  ATP  ATP+KLA
 NM_007464 baculoviral IAP repeat-containing 3 (Birc3), mRNA [NM_007464] KLA 17.83 15.88 13.48 11.14 11.79 6.90 6.10
ATP 1.14 1.16 1.70 4.07 5.00 6.33 2.41
KLA/ATP 14.77 16.44 19.09 13.91 8.27 6.22 7.73
Blnk
KLA  ATP  ATP+KLA
 NM_008528 B-cell linker (Blnk), mRNA [NM_008528] KLA 1.53 1.39 1.23 1.31 1.01 1.41 1.21
ATP .95 .81 1.09 .87 2.09 1.28 .97
KLA/ATP 1.21 1.23 1.44 1.00 2.09 1.88 1.39
Btk
KLA  ATP  ATP+KLA
 NM_013482 Bruton agammaglobulinemia tyrosine kinase (Btk), mRNA [NM_013482] KLA 1.10 1.24 1.01 1.33 1.07 1.27 1.01
ATP .95 1.05 .86 .97 .66 .72 .82
KLA/ATP 1.14 1.35 1.12 1.52 .96 .70 .82
Card11
KLA  ATP  ATP+KLA
 AK002346 adult male kidney cDNA, RIKEN full-length enriched library, clone:0610008L17 product:CASPASE RECRUITMENT DOMAIN PROTEIN 11 (CARD-CONTAINING MAGUK PROTEIN 3) (CARMA 1) homolog [Homo sapiens], full insert sequence. [AK002346] KLA .83 .86 .89 .91 1.13 .99 .99
ATP .97 .93 .89 .93 .88 .89 .98
KLA/ATP .91 .87 .89 .86 .88 .92 1.01
Card11
KLA  ATP  ATP+KLA
 NM_175362 caspase recruitment domain family, member 11 (Card11), mRNA [NM_175362] KLA .33 .29 .31 .44 .71 1.30 1.45
ATP .84 .68 .79 .71 .38 .26 .47
KLA/ATP .33 .27 .40 .35 .38 .37 .85
Ccl19
KLA  ATP  ATP+KLA
 NM_011888 chemokine (C-C motif) ligand 19 (Ccl19), mRNA [NM_011888] KLA 1.12 1.20 1.11 1.09 1.08 1.01 1.05
ATP .93 .99 1.01 1.01 .98 .95 1.03
KLA/ATP 1.12 1.21 1.16 1.13 1.08 .98 1.03
Ccl21b
KLA  ATP  ATP+KLA
 NM_011124 chemokine (C-C motif) ligand 21b (Ccl21b), mRNA [NM_011124] KLA 1.02 .97 .96 1.03 1.05 1.04 1.03
ATP .97 1.00 1.01 1.01 .94 1.03 1.01
KLA/ATP 1.08 .97 .96 1.00 1.06 1.03 1.02
Ccl4
KLA  ATP  ATP+KLA
 NM_013652 chemokine (C-C motif) ligand 4 (Ccl4), mRNA [NM_013652] KLA 68.93 60.20 52.12 67.06 35.78 15.78 8.82
ATP 2.26 3.82 16.88 43.14 26.67 9.47 6.75
KLA/ATP 59.57 71.75 133.98 193.53 81.76 15.96 7.62
Cd14
KLA  ATP  ATP+KLA
 NM_009841 CD14 antigen (Cd14), mRNA [NM_009841] KLA 2.35 2.68 2.54 2.21 2.39 1.52 1.57
ATP 1.44 2.28 2.82 3.98 6.68 16.14 6.92
KLA/ATP 2.92 3.79 3.96 5.12 5.29 10.42 11.50
Cd40
KLA  ATP  ATP+KLA
 NM_170701 CD40 antigen (Cd40), transcript variant 3, mRNA [NM_170701] KLA 23.87 23.62 23.26 23.98 22.07 17.37 5.34
ATP 1.00 1.01 1.06 2.96 2.65 3.03 1.70
KLA/ATP 22.77 23.79 29.67 28.85 28.08 21.62 13.02
Cd40lg
KLA  ATP  ATP+KLA
 NM_011616 CD40 ligand (Cd40lg), mRNA [NM_011616] KLA 1.03 1.07 1.02 .98 1.06 1.06 1.03
ATP .95 .92 .99 1.06 1.02 1.04 1.07
KLA/ATP 1.00 1.01 .93 1.04 .94 1.01 .98
Cflar
KLA  ATP  ATP+KLA
 NM_009805 CASP8 and FADD-like apoptosis regulator (Cflar), transcript variant 2, mRNA [NM_009805] KLA 18.63 20.03 20.30 17.44 17.99 11.88 7.25
ATP .95 1.03 1.20 2.78 4.04 3.45 3.30
KLA/ATP 19.31 19.09 11.65 13.57 7.62 6.20 11.21
Cflar
KLA  ATP  ATP+KLA
 NM_207653 CASP8 and FADD-like apoptosis regulator (Cflar), transcript variant 1, mRNA [NM_207653] KLA 12.32 12.86 11.83 11.79 12.14 8.52 5.42
ATP .92 .92 1.63 4.97 7.95 5.18 2.39
KLA/ATP 12.27 13.57 13.15 12.79 10.27 7.71 8.32
Cflar
KLA  ATP  ATP+KLA
 Y14041 mRNA for CASH alpha protein. [Y14041] KLA 14.31 13.82 13.05 13.06 14.36 9.02 5.92
ATP 1.18 1.15 1.66 6.44 8.99 5.20 2.73
KLA/ATP 15.53 17.07 14.00 17.10 10.76 8.02 9.97
Chuk
KLA  ATP  ATP+KLA
 NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Csnk2a1
KLA  ATP  ATP+KLA
 NM_007788 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA [NM_007788] KLA 1.36 1.39 1.19 1.34 1.32 1.74 1.86
ATP .92 .88 1.13 .86 1.12 2.50 1.99
KLA/ATP 1.19 1.24 1.35 1.03 1.16 2.09 2.88
Csnk2a2
KLA  ATP  ATP+KLA
 NM_009974 casein kinase 2, alpha prime polypeptide (Csnk2a2), mRNA [NM_009974] KLA 1.46 1.53 1.70 1.47 1.32 1.32 1.17
ATP 1.00 1.11 1.17 1.33 1.71 2.03 1.06
KLA/ATP 1.58 1.67 1.69 2.00 2.20 2.44 1.68
Csnk2b
KLA  ATP  ATP+KLA
 NM_009975 casein kinase 2, beta polypeptide (Csnk2b), mRNA [NM_009975] KLA 1.19 1.10 1.12 1.13 1.20 1.28 1.25
ATP 1.12 1.03 1.04 1.07 1.20 1.27 1.09
KLA/ATP 1.15 1.20 1.25 1.13 1.44 1.34 1.35
Cxcl12
KLA  ATP  ATP+KLA
 NM_001012477 chemokine (C-X-C motif) ligand 12 (Cxcl12), transcript variant 3, mRNA [NM_001012477] KLA .91 .91 .92 .92 .91 1.00 .85
ATP 1.00 .99 1.02 .99 .91 .93 .88
KLA/ATP .89 .91 .97 .97 .94 .93 .82
Cxcl12
KLA  ATP  ATP+KLA
 NM_021704 chemokine (C-X-C motif) ligand 12 (Cxcl12), transcript variant 1, mRNA [NM_021704] KLA 1.01 .96 1.04 1.04 .94 .98 .94
ATP 1.01 .92 .98 1.04 1.02 .94 .98
KLA/ATP 1.02 .98 1.07 .95 1.02 .98 .99
Cxcl2
KLA  ATP  ATP+KLA
 NM_009140 chemokine (C-X-C motif) ligand 2 (Cxcl2), mRNA [NM_009140] KLA 20.11 17.63 13.50 7.78 9.14 3.98 10.85
ATP 10.96 27.84 145.37 396.18 303.88 165.35 21.04
KLA/ATP 33.28 74.00 189.99 348.56 93.84 68.75 64.87
Ddx58
KLA  ATP  ATP+KLA
 NM_172689 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58), mRNA [NM_172689] KLA 8.80 9.12 9.70 9.96 9.92 7.85 5.67
ATP 1.06 .89 .97 .89 .80 3.03 3.67
KLA/ATP 9.18 9.23 10.31 9.25 7.29 6.93 8.99
EG629860
KLA  ATP  ATP+KLA
 M17953 gb|Mouse Ig rearranged H-chain V-region mRNA VJ1 [M17953] KLA .96 1.05 1.03 1.08 1.08 1.02 .98
ATP .97 .99 1.05 1.10 .95 .94 .91
KLA/ATP .96 .94 .97 1.04 .97 1.01 .89
Erc1
KLA  ATP  ATP+KLA
 NM_053204 ELKS/RAB6-interacting/CAST family member 1 (Erc1), transcript variant 1, mRNA [NM_053204] KLA 1.14 1.06 .94 .96 .81 .83 .81
ATP 1.06 1.00 .93 .81 .66 1.08 .99
KLA/ATP 1.02 1.05 1.04 .81 .64 .87 .85
Erc1
KLA  ATP  ATP+KLA
 NM_178085 ELKS/RAB6-interacting/CAST family member 1 (Erc1), transcript variant 2, mRNA [NM_178085] KLA .97 .93 .94 .92 .91 .85 .93
ATP 1.01 1.01 .99 .96 .93 1.04 1.04
KLA/ATP .96 .96 .93 .93 .89 .88 .96
Gadd45b
KLA  ATP  ATP+KLA
 NM_008655 growth arrest and DNA-damage-inducible 45 beta (Gadd45b), mRNA [NM_008655] KLA 10.08 11.65 8.40 11.27 8.24 7.30 5.74
ATP 1.83 3.28 10.08 27.60 15.97 8.84 4.61
KLA/ATP 9.36 14.99 21.30 45.24 49.27 21.63 22.73
Icam1
KLA  ATP  ATP+KLA
 BC008626 intercellular adhesion molecule, mRNA (cDNA clone MGC:6195 IMAGE:3588949), complete cds [BC008626] KLA 36.67 32.93 28.63 27.91 14.65 8.16 4.15
ATP .96 .88 1.50 3.88 4.98 3.90 1.01
KLA/ATP 32.58 31.60 42.74 32.60 26.00 13.02 6.01
Icam1
KLA  ATP  ATP+KLA
 NM_010493 intercellular adhesion molecule 1 (Icam1), mRNA [NM_010493] KLA 15.66 15.20 12.96 12.31 9.39 6.17 3.81
ATP .96 1.06 1.21 4.19 4.33 3.16 1.06
KLA/ATP 14.31 15.46 17.84 17.60 13.77 8.36 5.42
Igh-VJ55
8
KLA  ATP  ATP+KLA
 AY547436 immunoglobulin heavy chain VDJ region mRNA, partial cds [AY547436] KLA 1.06 1.05 1.01 .93 1.03 .96 .93
ATP .99 1.00 1.06 .95 .96 1.06 1.05
KLA/ATP .98 .94 1.07 .95 .97 .99 1.02
Igh-VJ55
8
KLA  ATP  ATP+KLA
 CA578712 gb|K0727F04-5N NIA Mouse Hematopoietic Stem Cell (Lin- [CA578712] KLA .99 .94 1.01 1.10 .93 .97 .92
ATP .93 1.04 1.01 .98 1.05 .96 .95
KLA/ATP .99 .95 .95 .98 1.02 .98 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103412 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHA] [ENSMUST00000103412] KLA 1.01 .97 1.20 1.01 .98 1.44 1.24
ATP .99 .98 1.07 1.03 1.00 1.01 1.21
KLA/ATP .99 1.02 .96 1.03 .97 1.13 1.30
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103413 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHE] [ENSMUST00000103413] KLA 1.00 .99 1.06 1.06 .99 1.03 1.02
ATP 1.08 1.06 1.06 1.06 1.02 1.06 .95
KLA/ATP 1.00 1.04 1.09 1.02 1.06 1.02 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 U39781 J558+ IgM heavy chain mRNA, hybridoma clone ME2B7, partial cds. [U39781] KLA .93 .89 .98 .97 1.03 1.00 .94
ATP 1.04 1.02 1.08 .94 .93 .90 .79
KLA/ATP .88 .89 .97 .93 .88 .92 .82
Ikbkb
KLA  ATP  ATP+KLA
 NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbkg
KLA  ATP  ATP+KLA
 AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
 NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
 NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Il1b
KLA  ATP  ATP+KLA
 NM_008361 interleukin 1 beta (Il1b), mRNA [NM_008361] KLA 149.78 133.59 100.91 116.58 86.48 89.37 64.72
ATP 3.49 13.96 61.44 70.91 82.12 162.79 28.18
KLA/ATP 130.32 139.00 219.12 148.17 165.44 172.57 146.98
Il1r1
KLA  ATP  ATP+KLA
 NM_008362 interleukin 1 receptor, type I (Il1r1), transcript variant 1, mRNA [NM_008362] KLA 1.20 1.08 1.22 1.52 2.19 2.32 1.61
ATP 1.10 .96 1.18 1.56 8.14 9.56 7.54
KLA/ATP 1.22 1.13 1.37 1.85 4.54 6.85 8.96
Irak1
KLA  ATP  ATP+KLA
 NM_008363 interleukin-1 receptor-associated kinase 1 (Irak1), mRNA [NM_008363] KLA .67 .67 .64 .56 .58 .58 .84
ATP 1.02 1.10 .94 1.14 .81 .54 .87
KLA/ATP .72 .72 .57 .67 .51 .43 .62
Irak4
KLA  ATP  ATP+KLA
 NM_029926 interleukin-1 receptor-associated kinase 4 (Irak4), mRNA [NM_029926] KLA .82 .86 .78 .82 .95 1.21 1.22
ATP 1.02 1.18 .95 1.10 .79 .85 .82
KLA/ATP .86 .89 .77 .90 .78 .96 .88
Lat
KLA  ATP  ATP+KLA
 NM_010689 linker for activation of T cells (Lat), mRNA [NM_010689] KLA .91 .95 .94 .87 .76 .63 .48
ATP .97 .99 1.01 1.50 1.59 1.49 1.00
KLA/ATP .91 1.04 .93 1.15 1.11 .96 .65
Lbp
KLA  ATP  ATP+KLA
 NM_008489 lipopolysaccharide binding protein (Lbp), mRNA [NM_008489] KLA 1.01 1.01 .94 1.02 1.03 1.06 1.00
ATP 1.00 .99 .96 1.03 .91 .89 .84
KLA/ATP .98 .96 1.01 .93 1.00 .95 .83
Lck
KLA  ATP  ATP+KLA
 NM_010693 lymphocyte protein tyrosine kinase (Lck), mRNA [NM_010693] KLA 18.74 17.97 23.64 20.20 17.34 8.29 1.29
ATP 1.00 1.04 1.28 1.30 1.48 2.55 1.44
KLA/ATP 21.76 24.22 23.73 23.04 22.66 12.06 2.90
LOC10004
6483
KLA  ATP  ATP+KLA
 XM_001476285 ref|PREDICTED: Mus musculus similar to casein kinase II, alpha prime subunit (LOC100046483), mRNA [XM_001476285] KLA .97 .94 .94 .88 .84 .76 .88
ATP 1.06 1.04 .89 .82 .87 .70 .56
KLA/ATP 1.03 1.00 .88 .75 .73 .66 .43
Lrdd
KLA  ATP  ATP+KLA
 NM_022654 leucine-rich and death domain containing (Lrdd), mRNA [NM_022654] KLA .93 .97 1.01 .99 .96 1.02 .78
ATP 1.03 1.01 .91 .91 .75 .82 .73
KLA/ATP 1.02 1.03 1.06 1.27 1.01 1.03 .95
Lta
KLA  ATP  ATP+KLA
 NM_010735 lymphotoxin A (Lta), mRNA [NM_010735] KLA 1.95 2.18 2.41 2.18 2.50 2.26 1.79
ATP 1.01 1.00 1.10 1.55 1.24 1.09 1.07
KLA/ATP 2.16 2.23 1.85 2.11 1.60 1.31 1.33
Ltb
KLA  ATP  ATP+KLA
 NM_008518 lymphotoxin B (Ltb), mRNA [NM_008518] KLA 2.41 2.52 2.49 3.05 3.54 4.63 1.94
ATP 1.00 .92 1.28 1.57 1.77 1.64 .98
KLA/ATP 2.22 2.68 2.81 3.15 4.88 4.53 2.01
Ltbr
KLA  ATP  ATP+KLA
 NM_010736 lymphotoxin B receptor (Ltbr), mRNA [NM_010736] KLA .78 .77 .80 .95 1.08 1.39 1.36
ATP .94 .86 1.00 .83 .74 1.18 1.37
KLA/ATP .69 .71 .74 .68 .85 1.04 1.69
Ly96
KLA  ATP  ATP+KLA
 NM_016923 lymphocyte antigen 96 (Ly96), mRNA [NM_016923] KLA 2.25 2.07 2.39 2.38 2.38 2.30 2.14
ATP 1.19 1.02 1.35 1.20 1.69 2.83 1.93
KLA/ATP 2.36 2.28 3.07 2.62 2.68 2.34 3.13
Lyn
KLA  ATP  ATP+KLA
 NM_010747 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog (Lyn), transcript variant 2, mRNA [NM_010747] KLA 2.48 2.80 3.76 3.81 5.30 4.57 2.46
ATP 1.06 1.18 .82 .97 .74 1.45 1.21
KLA/ATP 2.82 3.16 2.24 2.87 1.73 1.80 2.63
Malt1
KLA  ATP  ATP+KLA
 AK172081 activated spleen cDNA, RIKEN full-length enriched library, clone:F830035G05 product:unclassifiable, full insert sequence [AK172081] KLA 8.85 8.52 6.90 6.44 8.01 3.16 3.02
ATP 1.37 1.55 2.57 6.23 6.73 5.82 1.27
KLA/ATP 9.01 10.69 14.85 12.51 4.33 4.50 6.89
Malt1
KLA  ATP  ATP+KLA
 NM_172833 mucosa associated lymphoid tissue lymphoma translocation gene 1 (Malt1), mRNA [NM_172833] KLA 17.74 16.14 15.00 9.66 9.87 4.22 3.54
ATP 1.20 1.19 2.20 5.12 10.20 8.16 1.25
KLA/ATP 19.07 18.41 21.75 20.07 13.32 7.72 8.40
Map3k14
KLA  ATP  ATP+KLA
 NM_016896 mitogen-activated protein kinase kinase kinase 14 (Map3k14), mRNA [NM_016896] KLA .32 .30 .40 .52 1.08 1.14 .94
ATP 1.18 1.24 1.13 .85 .82 .84 .99
KLA/ATP .33 .30 .34 .50 1.02 .84 1.43
Map3k7
KLA  ATP  ATP+KLA
 NM_172688 mitogen-activated protein kinase kinase kinase 7 (Map3k7), mRNA [NM_172688] KLA 1.48 1.49 1.51 1.24 1.21 1.19 1.61
ATP 1.10 1.16 1.03 1.03 1.12 1.61 1.61
KLA/ATP 1.43 1.56 1.05 1.15 .85 1.48 1.76
Map3k7ip
1
KLA  ATP  ATP+KLA
 NM_025609 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Map3k7ip1), mRNA [NM_025609] KLA .32 .30 .35 .56 .67 .82 .76
ATP .95 .81 .80 .42 .35 .40 .80
KLA/ATP .33 .30 .37 .20 .45 .62 .65
Map3k7ip
2
KLA  ATP  ATP+KLA
 AK086230 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930015C19 product:inferred: Mus musculus, Similar to TAK1-binding protein 2; KIAA0733 protein, clone MGC:8010 IMAGE:3586132, mRNA, complete cds, full insert sequence. [A KLA 1.14 1.02 1.07 1.03 1.13 1.02 .96
ATP 1.00 .88 .92 .90 1.06 .96 .94
KLA/ATP 1.05 1.00 .90 .98 1.02 .97 .97
Map3k7ip
2
KLA  ATP  ATP+KLA
 NM_138667 mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (Map3k7ip2), mRNA [NM_138667] KLA 3.43 3.22 3.19 2.41 2.13 1.51 1.10
ATP 1.08 1.08 .86 .81 1.30 1.32 1.02
KLA/ATP 3.34 3.66 3.00 2.58 1.80 1.52 1.61
Map3k7ip
3
KLA  ATP  ATP+KLA
 NM_025729 mitogen-activated protein kinase kinase kinase 7 interacting protein 3 (Map3k7ip3), mRNA [NM_025729] KLA 1.21 1.05 1.20 1.24 1.12 1.26 1.18
ATP 1.02 .88 1.07 .64 1.38 1.88 .95
KLA/ATP 1.13 1.11 1.21 .75 1.58 1.74 1.38
Mm.14928
0
KLA  ATP  ATP+KLA
 34328395 Unknown KLA 1.35 1.44 1.59 1.51 1.51 1.28 1.54
ATP .98 .97 1.05 1.08 1.19 .75 .71
KLA/ATP 1.31 1.34 1.22 1.42 1.28 .89 .95
Mm.15898
1
KLA  ATP  ATP+KLA
 142388182 Unknown KLA .25 .22 .31 .50 .85 1.11 .83
ATP 1.02 .94 1.31 .76 .73 .96 .92
KLA/ATP .24 .22 .34 .38 1.16 .96 1.23
Mm.1741
KLA  ATP  ATP+KLA
 31982052 Unknown KLA 4.05 3.90 3.12 3.55 4.00 3.37 2.25
ATP 1.01 1.01 1.44 2.36 3.07 3.54 1.27
KLA/ATP 4.19 3.74 4.02 4.02 3.13 2.82 3.33
Mm.23692
KLA  ATP  ATP+KLA
 164565453 Unknown KLA .83 .77 .72 .65 .61 .75 .80
ATP .77 .94 1.03 .63 .61 .74 .59
KLA/ATP .58 .78 .77 .52 .51 .56 .30
Mm.24004
7
KLA  ATP  ATP+KLA
 118130430 Unknown KLA 1.09 1.07 1.01 1.00 1.04 1.05 .97
ATP .98 1.00 1.05 .97 1.05 1.02 1.05
KLA/ATP .98 1.04 1.16 1.06 1.06 .96 1.02
Mm.33565
9
KLA  ATP  ATP+KLA
 160333365 Unknown KLA 5.54 4.69 3.93 3.03 2.00 1.91 1.69
ATP .98 .81 1.01 .78 .68 1.71 1.10
KLA/ATP 5.05 4.44 5.07 2.38 1.34 1.88 2.00
Mm.38049
KLA  ATP  ATP+KLA
 118130391 Unknown KLA .67 .65 .73 .92 .63 .81 .76
ATP .93 .92 1.08 .54 .45 1.48 1.56
KLA/ATP .57 .65 .98 .67 .44 .78 1.16
Mm.44463
KLA  ATP  ATP+KLA
 118129851 Unknown KLA 1.01 .98 .97 1.02 .93 1.06 1.05
ATP .97 1.01 1.04 1.06 1.02 1.08 .97
KLA/ATP 1.02 1.06 .95 1.04 1.09 1.14 1.03
Mm.46002
4
KLA  ATP  ATP+KLA
 38348245 Unknown KLA 1.22 1.25 1.25 1.19 1.22 1.47 1.14
ATP 1.03 .94 1.01 1.01 2.67 2.31 1.37
KLA/ATP 1.35 1.19 1.27 1.22 1.99 1.83 1.45
Myd88
KLA  ATP  ATP+KLA
 NM_010851 myeloid differentiation primary response gene 88 (Myd88), mRNA [NM_010851] KLA 3.35 3.51 3.91 4.13 4.13 3.62 2.53
ATP .99 .96 .79 .75 .93 2.15 1.60
KLA/ATP 3.37 3.52 3.52 3.48 2.81 3.03 3.33
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkb2
KLA  ATP  ATP+KLA
 NM_019408 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 (Nfkb2), mRNA [NM_019408] KLA 7.31 7.92 7.95 6.42 6.41 4.42 2.81
ATP .99 .98 .72 1.48 2.80 5.31 1.44
KLA/ATP 8.25 7.93 6.51 7.68 5.08 4.38 4.86
Nfkbia
KLA  ATP  ATP+KLA
 NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Parp1
KLA  ATP  ATP+KLA
 NM_007415 poly (ADP-ribose) polymerase family, member 1 (Parp1), mRNA [NM_007415] KLA .56 .58 .56 .44 .45 .46 .49
ATP 1.03 1.11 .93 .92 .66 .20 .46
KLA/ATP .65 .55 .46 .54 .33 .24 .22
Parp1
KLA  ATP  ATP+KLA
 X14206 gb|Mouse mRNA for poly (ADP-ribose) polymerase (EC 2.4.2.30). [X14206] KLA .57 .56 .54 .43 .40 .42 .47
ATP 1.01 1.09 .95 .95 .59 .19 .43
KLA/ATP .59 .55 .46 .49 .32 .20 .20
Pias4
KLA  ATP  ATP+KLA
 NM_021501 protein inhibitor of activated STAT 4 (Pias4), mRNA [NM_021501] KLA .97 1.13 1.26 1.38 1.87 1.63 1.62
ATP 1.12 1.30 .89 1.24 1.93 1.64 1.92
KLA/ATP 1.33 1.11 .74 1.30 1.61 2.07 2.69
Plau
KLA  ATP  ATP+KLA
 NM_008873 plasminogen activator, urokinase (Plau), mRNA [NM_008873] KLA .28 .27 .22 .23 .19 .25 .27
ATP .99 1.19 1.63 2.44 1.52 .49 1.12
KLA/ATP .26 .29 .32 .40 .35 .32 .48
Plcg2
KLA  ATP  ATP+KLA
 NM_172285 phospholipase C, gamma 2 (Plcg2), mRNA [NM_172285] KLA .76 .74 .68 .66 .71 .92 .95
ATP .96 .90 .95 .87 .81 .79 .91
KLA/ATP .76 .71 .69 .62 .72 .78 .68
Prkcb1
KLA  ATP  ATP+KLA
 NM_008855 protein kinase C, beta 1 (Prkcb1), mRNA [NM_008855] KLA .92 .95 .93 .78 .77 1.08 1.83
ATP 1.03 1.12 1.09 1.23 .90 2.08 .96
KLA/ATP .98 .99 .82 .89 .62 1.01 1.08
Prkcq
KLA  ATP  ATP+KLA
 AK085546 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630039J01 product:protein kinase C, theta, full insert sequence [AK085546] KLA .98 .99 1.01 1.00 .95 .98 .97
ATP 1.06 .98 1.02 1.00 .99 .99 1.04
KLA/ATP .91 1.01 .84 1.02 1.03 1.00 1.03
Prkcq
KLA  ATP  ATP+KLA
 NM_008859 protein kinase C, theta (Prkcq), mRNA [NM_008859] KLA 1.04 1.07 1.00 1.06 1.02 .91 .87
ATP 1.06 .97 .97 .99 .94 1.00 .89
KLA/ATP 1.09 1.00 1.15 1.14 .98 1.07 .96
Ptgs2
KLA  ATP  ATP+KLA
 NM_011198 prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA [NM_011198] KLA 181.04 220.88 218.58 132.79 103.05 22.69 18.02
ATP 2.47 9.45 52.13 208.62 271.22 306.11 6.86
KLA/ATP 233.39 387.29 617.86 ###.## 608.44 290.80 112.22
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Relb
KLA  ATP  ATP+KLA
 NM_009046 avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb), mRNA [NM_009046] KLA 4.39 4.46 3.54 3.47 4.36 3.18 2.72
ATP 1.01 1.07 1.23 2.66 3.23 3.50 1.24
KLA/ATP 4.43 4.52 3.56 4.10 2.85 2.92 3.30
Ripk1
KLA  ATP  ATP+KLA
 NM_009068 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), mRNA [NM_009068] KLA 1.32 1.33 1.50 1.09 1.00 1.11 1.13
ATP .98 .94 .60 .59 1.35 1.56 1.45
KLA/ATP 1.48 1.30 1.01 1.05 1.36 1.53 1.37
Syk
KLA  ATP  ATP+KLA
 NM_011518 spleen tyrosine kinase (Syk), mRNA [NM_011518] KLA 2.48 2.59 2.57 2.26 3.29 3.75 3.19
ATP .96 .85 .59 1.01 2.80 3.77 2.11
KLA/ATP 2.56 2.09 1.16 1.35 2.50 4.33 5.10
Ticam1
KLA  ATP  ATP+KLA
 NM_174989 toll-like receptor adaptor molecule 1 (Ticam1), mRNA [NM_174989] KLA 1.45 1.63 2.02 2.36 3.12 2.34 2.21
ATP 1.16 1.19 .90 2.58 4.78 2.04 1.80
KLA/ATP 1.79 1.71 1.07 2.89 5.60 3.26 3.50
Ticam2
KLA  ATP  ATP+KLA
 NM_173394 toll-like receptor adaptor molecule 2 (Ticam2), mRNA [NM_173394] KLA 1.28 1.35 1.64 1.79 1.80 1.34 2.01
ATP 1.02 1.02 1.00 1.14 1.16 .70 .88
KLA/ATP 1.49 1.50 1.14 1.41 1.13 .89 1.40
Tirap
KLA  ATP  ATP+KLA
 AK081514 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130027E04 product:toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, full insert sequence [AK081514] KLA 1.36 1.33 1.35 1.41 1.36 1.45 1.22
ATP .93 .87 .82 .45 .78 1.93 1.32
KLA/ATP 1.35 1.37 1.30 .83 1.17 1.75 2.10
Tirap
KLA  ATP  ATP+KLA
 NM_054096 toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap), mRNA [NM_054096] KLA 1.88 1.70 1.69 1.74 1.82 1.69 1.31
ATP 1.12 1.10 .75 .56 1.03 2.52 1.67
KLA/ATP 1.60 1.75 1.69 1.25 1.41 2.27 3.21
Tlr4
KLA  ATP  ATP+KLA
 NM_021297 toll-like receptor 4 (Tlr4), mRNA [NM_021297] KLA .69 .61 .75 .94 .64 .81 .73
ATP .95 .90 1.12 .56 .47 1.51 1.53
KLA/ATP .57 .62 1.01 .64 .39 .73 1.13
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Tnfaip3
KLA  ATP  ATP+KLA
 NM_009397 tumor necrosis factor, alpha-induced protein 3 (Tnfaip3), mRNA [NM_009397] KLA 29.69 27.73 21.42 18.86 14.42 8.13 7.48
ATP 1.73 4.86 21.57 43.06 30.03 18.86 8.31
KLA/ATP 29.39 35.88 40.64 52.71 33.19 25.38 17.75
Tnfrsf11
a
KLA  ATP  ATP+KLA
 NM_009399 tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a), mRNA [NM_009399] KLA 1.43 1.33 1.36 1.58 1.87 1.83 1.47
ATP 1.07 1.17 1.02 1.19 .95 .82 1.13
KLA/ATP 1.55 1.46 1.16 1.46 .79 .95 1.92
Tnfrsf13
c
KLA  ATP  ATP+KLA
 NM_028075 tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c), mRNA [NM_028075] KLA 1.05 1.04 1.05 1.01 1.05 1.00 .92
ATP 1.03 1.01 1.01 .99 1.04 1.03 1.04
KLA/ATP 1.05 1.07 1.10 1.04 1.02 .94 1.00
Tnfrsf1a
KLA  ATP  ATP+KLA
 NM_011609 tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a), mRNA [NM_011609] KLA 1.74 1.71 1.90 2.16 1.95 1.74 1.16
ATP .95 .83 .55 .41 .41 1.55 1.32
KLA/ATP 1.58 1.49 1.19 1.03 .98 2.02 2.10
Tnfsf11
KLA  ATP  ATP+KLA
 NM_011613 tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11), mRNA [NM_011613] KLA 1.00 1.00 1.08 .96 .97 1.01 .96
ATP 1.01 1.05 .97 .86 1.05 1.03 1.01
KLA/ATP 1.04 1.05 .99 1.04 1.01 1.02 .99
Tnfsf13b
KLA  ATP  ATP+KLA
 ENSMUST00000033892 ens|Tumor necrosis factor ligand superfamily member 13B (B cell-activating factor) (BAFF) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]. [ KLA .95 .99 .93 .92 .94 .94 .92
ATP .90 .92 1.01 .91 .93 .95 .92
KLA/ATP .94 .89 1.17 1.03 .98 .93 .90
Tnfsf13b
KLA  ATP  ATP+KLA
 NM_033622 tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b), mRNA [NM_033622] KLA .87 .87 .92 .79 .74 .80 1.17
ATP .97 .87 .83 .81 .79 .57 .38
KLA/ATP .91 .86 .87 .88 1.02 .89 .49
Tnfsf14
KLA  ATP  ATP+KLA
 NM_019418 tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14), mRNA [NM_019418] KLA .57 .66 .55 .82 .48 .29 .22
ATP 1.16 1.25 1.61 8.55 24.98 15.54 3.28
KLA/ATP .88 .70 .86 3.41 17.39 10.12 1.56
Tradd
KLA  ATP  ATP+KLA
 NM_001033161 TNFRSF1A-associated via death domain (Tradd), mRNA [NM_001033161] KLA .77 .71 .82 .89 .89 1.11 1.06
ATP 1.00 .90 1.01 .73 .59 1.34 1.50
KLA/ATP .79 .73 .83 .63 .72 1.11 1.73
Traf1
KLA  ATP  ATP+KLA
 NM_009421 Tnf receptor-associated factor 1 (Traf1), mRNA [NM_009421] KLA 44.86 39.03 38.11 34.21 36.49 19.69 14.75
ATP 1.14 1.04 1.98 8.16 16.79 30.81 6.36
KLA/ATP 46.20 45.67 45.63 38.00 27.26 31.47 63.83
Traf2
KLA  ATP  ATP+KLA
 NM_009422 Tnf receptor-associated factor 2 (Traf2), mRNA [NM_009422] KLA 3.38 3.62 3.49 3.36 3.49 3.39 2.68
ATP .97 1.04 1.00 1.10 1.54 2.40 1.55
KLA/ATP 3.38 3.16 2.93 2.74 2.67 3.11 4.70
Traf3
KLA  ATP  ATP+KLA
 NM_011632 Tnf receptor-associated factor 3 (Traf3), transcript variant 1, mRNA [NM_011632] KLA .52 .49 .51 .49 .80 .98 1.22
ATP .93 .92 .95 1.13 2.70 1.80 1.42
KLA/ATP .56 .50 .49 1.07 2.94 1.92 1.65
Traf5
KLA  ATP  ATP+KLA
 NM_011633 Tnf receptor-associated factor 5 (Traf5), mRNA [NM_011633] KLA 1.82 1.92 1.93 2.10 2.75 2.08 1.00
ATP 1.02 1.04 1.10 .78 3.79 2.22 1.42
KLA/ATP 1.70 1.89 1.85 1.64 5.40 2.10 1.83
Traf6
KLA  ATP  ATP+KLA
 NM_009424 Tnf receptor-associated factor 6 (Traf6), mRNA [NM_009424] KLA 1.19 1.28 1.34 1.20 1.23 1.23 1.28
ATP 1.06 1.12 .92 1.15 2.46 1.84 1.40
KLA/ATP 1.32 1.37 .89 1.16 1.45 1.49 1.46
Trim25
KLA  ATP  ATP+KLA
 NM_009546 tripartite motif-containing 25 (Trim25), mRNA [NM_009546] KLA 3.93 4.08 4.13 3.67 3.19 3.12 3.13
ATP 1.02 1.00 .92 1.22 2.80 3.73 3.72
KLA/ATP 4.17 4.41 4.23 4.23 5.38 5.22 7.68
Ube2i
KLA  ATP  ATP+KLA
 BC037635 ubiquitin-conjugating enzyme E2I, mRNA (cDNA clone MGC:46871 IMAGE:4951933), complete cds. [BC037635] KLA .79 .80 .78 .82 .95 .90 .98
ATP .96 1.00 .77 .96 1.41 1.01 1.00
KLA/ATP .80 .83 .68 .89 1.03 .93 .79
Ube2i
KLA  ATP  ATP+KLA
 NM_011665 ubiquitin-conjugating enzyme E2I (Ube2i), mRNA [NM_011665] KLA .75 .76 .74 .71 .70 .63 .78
ATP 1.03 1.02 .95 1.02 .93 .66 .75
KLA/ATP .81 .80 .71 .80 .75 .60 .61
Vcam1
KLA  ATP  ATP+KLA
 NM_011693 vascular cell adhesion molecule 1 (Vcam1), mRNA [NM_011693] KLA 18.71 22.30 20.87 18.09 13.61 6.09 2.09
ATP 1.08 1.00 1.56 4.23 5.09 5.04 1.50
KLA/ATP 19.09 25.02 26.43 25.42 20.08 11.45 6.67
Xiap
KLA  ATP  ATP+KLA
 NM_009688 X-linked inhibitor of apoptosis (Xiap), mRNA [NM_009688] KLA 1.61 1.63 1.62 1.52 1.34 1.27 1.11
ATP 1.03 1.01 .99 .96 .88 1.19 1.25
KLA/ATP 1.64 1.63 1.54 1.33 1.08 1.19 1.72
Zap70
KLA  ATP  ATP+KLA
 NM_009539 zeta-chain (TCR) associated protein kinase (Zap70), mRNA [NM_009539] KLA .94 .88 .84 .86 1.01 .92 .94
ATP 1.02 .99 .87 .87 1.58 .98 .96
KLA/ATP .94 .82 .83 .77 1.09 .93 1.02