Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: RIG-I-like receptor signaling pathway (mmu04622)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
5730470L
24Rik
KLA  ATP  ATP+KLA
 AK012679 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810005O12 product:hypothetical protein, full insert sequence. [AK012679] KLA 1.11 1.01 1.04 1.15 .99 1.28 1.33
ATP .91 .86 1.27 1.00 .64 1.28 1.71
KLA/ATP .98 1.11 1.51 1.04 .81 .87 1.74
5730470L
24Rik
KLA  ATP  ATP+KLA
 NM_025679 RIKEN cDNA 5730470L24 gene (5730470L24Rik), mRNA [NM_025679] KLA .68 .69 .75 .63 .77 .88 .86
ATP .91 .89 .82 .52 .41 .83 .89
KLA/ATP .69 .66 .57 .40 .40 .60 .85
Atg12
KLA  ATP  ATP+KLA
 NM_026217 autophagy-related 12 (yeast) (Atg12), mRNA [NM_026217] KLA 1.06 1.08 1.12 1.28 1.24 1.30 1.22
ATP 1.00 .97 1.09 1.32 2.01 2.37 1.51
KLA/ATP 1.02 1.13 1.38 1.34 1.99 2.27 2.13
Atg5
KLA  ATP  ATP+KLA
 NM_053069 autophagy-related 5 (yeast) (Atg5), mRNA [NM_053069] KLA 1.09 1.12 .93 1.12 1.26 1.63 2.23
ATP .95 .96 1.01 .89 .80 1.87 1.85
KLA/ATP .99 .98 .90 .90 .92 1.81 2.10
Azi2
KLA  ATP  ATP+KLA
 NM_013727 5-azacytidine induced gene 2 (Azi2), transcript variant 1, mRNA [NM_013727] KLA 5.19 5.17 6.08 5.88 5.63 4.25 2.81
ATP .97 .91 .87 .65 .79 1.94 1.68
KLA/ATP 4.89 4.89 4.77 3.28 2.37 2.93 3.32
Casp8
KLA  ATP  ATP+KLA
 NM_009812 caspase 8 (Casp8), transcript variant 1, mRNA [NM_009812] KLA 2.41 2.53 3.20 3.26 2.75 2.78 1.57
ATP .91 .96 .66 .67 .54 1.53 1.52
KLA/ATP 2.47 2.52 2.08 2.41 1.41 2.50 2.77
Chuk
KLA  ATP  ATP+KLA
 NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Cxcl10
KLA  ATP  ATP+KLA
 NM_021274 chemokine (C-X-C motif) ligand 10 (Cxcl10), mRNA [NM_021274] KLA 986.69 854.98 711.49 799.39 542.62 686.82 183.27
ATP .98 1.71 9.85 73.04 100.42 184.63 8.33
KLA/ATP 842.13 793.12 ###.## ###.## ###.## 715.22 496.10
Cyld
KLA  ATP  ATP+KLA
 AK147204 15 days pregnant adult female placenta cDNA, RIKEN full-length enriched library, clone:M421001K23 product:cylindromatosis (turban tumor syndrome), full insert sequence [AK147204] KLA .85 .83 .73 .65 .62 .61 .48
ATP .88 .79 .69 .47 .44 .43 .21
KLA/ATP .75 .66 .63 .42 .57 .41 .21
Cyld
KLA  ATP  ATP+KLA
 NM_173369 cylindromatosis (turban tumor syndrome) (Cyld), mRNA [NM_173369] KLA 1.64 1.65 1.53 1.74 1.66 1.46 1.30
ATP 1.05 1.14 1.04 .84 .75 .96 1.00
KLA/ATP 1.60 1.77 1.64 1.22 .93 1.00 1.28
D1Pas1
KLA  ATP  ATP+KLA
 NM_033077 DNA segment, Chr 1, Pasteur Institute 1 (D1Pas1), mRNA [NM_033077] KLA 1.05 1.01 1.03 .94 .90 .78 .79
ATP 1.05 1.14 1.01 1.26 1.15 .97 .79
KLA/ATP 1.04 1.09 1.06 1.18 .97 .86 .80
D430028G
21Rik
KLA  ATP  ATP+KLA
 NM_144888 RIKEN cDNA D430028G21 gene (D430028G21Rik), mRNA [NM_144888] KLA .56 .54 .61 .60 .74 1.03 1.06
ATP 1.07 .99 .69 .66 .48 .96 1.38
KLA/ATP .61 .60 .38 .41 .42 1.00 1.40
Dak
KLA  ATP  ATP+KLA
 NM_145496 dihydroxyacetone kinase 2 homolog (yeast) (Dak), mRNA [NM_145496] KLA 1.00 1.03 1.04 .98 1.06 .90 .85
ATP 1.13 1.16 .89 1.01 .74 .67 .85
KLA/ATP 1.07 1.07 .90 .98 .66 .56 .81
Ddx3x
KLA  ATP  ATP+KLA
 NM_010028 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x), mRNA [NM_010028] KLA 1.00 1.03 1.01 .90 .76 .56 .66
ATP 1.18 1.17 1.11 1.24 1.16 .93 .62
KLA/ATP 1.04 1.20 1.21 1.10 .89 .73 .59
Ddx3x
KLA  ATP  ATP+KLA
 U42386 fibroblast growth factor inducible gene 14 (FIN14) mRNA, complete cds. [U42386] KLA .72 .68 .66 .63 .49 .40 .43
ATP .99 .91 1.27 .93 1.14 1.01 .32
KLA/ATP .72 .81 .92 .75 1.00 .68 .20
Ddx3y
KLA  ATP  ATP+KLA
 AK020213 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030469F12 product:unclassifiable, full insert sequence. [AK020213] KLA 1.08 .99 1.03 1.07 .97 1.14 1.02
ATP .99 1.01 1.33 .98 .75 .98 .79
KLA/ATP .98 1.02 1.15 .84 .76 .89 .91
Ddx3y
KLA  ATP  ATP+KLA
 NM_012008 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (Ddx3y), mRNA [NM_012008] KLA 1.10 1.07 1.03 .97 1.20 1.07 .88
ATP 1.21 1.25 1.24 .87 .85 .94 .77
KLA/ATP 1.05 1.09 1.08 .76 .60 .71 .85
Ddx58
KLA  ATP  ATP+KLA
 NM_172689 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58), mRNA [NM_172689] KLA 8.80 9.12 9.70 9.96 9.92 7.85 5.67
ATP 1.06 .89 .97 .89 .80 3.03 3.67
KLA/ATP 9.18 9.23 10.31 9.25 7.29 6.93 8.99
Dhx58
KLA  ATP  ATP+KLA
 AK021012 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430001I08 product:hypothetical DEAD/DEAH box helicase containing protein, full insert sequence. [AK021012] KLA 1.57 1.44 1.55 1.70 1.73 1.97 1.90
ATP .97 .95 1.19 1.21 1.06 1.49 4.28
KLA/ATP 1.58 1.77 2.19 2.19 2.01 1.83 3.45
Dhx58
KLA  ATP  ATP+KLA
 NM_030150 DEXH (Asp-Glu-X-His) box polypeptide 58 (Dhx58), mRNA [NM_030150] KLA 4.02 3.96 4.24 4.94 4.39 3.54 4.14
ATP .96 .95 1.00 .98 .61 2.31 4.16
KLA/ATP 3.90 4.23 4.86 5.46 5.23 4.46 5.70
Fadd
KLA  ATP  ATP+KLA
 NM_010175 Fas (TNFRSF6)-associated via death domain (Fadd), mRNA [NM_010175] KLA .54 .54 .59 .64 .80 .97 1.16
ATP 1.05 1.09 1.03 1.65 1.18 .78 1.61
KLA/ATP .56 .56 .53 .78 .78 .82 1.34
Ifih1
KLA  ATP  ATP+KLA
 NM_027835 interferon induced with helicase C domain 1 (Ifih1), mRNA [NM_027835] KLA 37.11 33.14 35.90 33.98 21.58 12.10 6.89
ATP 1.03 .97 .74 .73 1.20 4.28 2.92
KLA/ATP 33.28 36.92 27.96 24.80 12.35 8.39 10.11
Ifna12
KLA  ATP  ATP+KLA
 NM_177361 interferon alpha 12 (Ifna12), mRNA [NM_177361] KLA 1.25 1.26 1.34 1.16 1.06 1.10 1.09
ATP 1.01 .97 1.07 1.09 1.17 1.20 1.07
KLA/ATP 1.12 1.29 1.72 1.54 1.59 1.56 1.05
Ifna13
KLA  ATP  ATP+KLA
 NM_177347 interferon alpha 13 (Ifna13), mRNA [NM_177347] KLA 1.32 1.27 1.26 1.34 1.15 1.24 1.20
ATP .95 1.08 1.29 1.79 1.41 1.22 1.08
KLA/ATP 1.36 1.35 2.04 2.81 2.07 1.44 1.19
Ifna2
KLA  ATP  ATP+KLA
 K01411 gb|Mouse alpha-interferon (MuIFN-alpha), 3 cds & untranslated mRNA [K01411] KLA 1.02 1.03 1.10 .96 .93 .99 1.01
ATP 1.02 .98 1.00 .98 1.02 .97 .95
KLA/ATP 1.02 1.04 1.18 1.08 1.13 1.04 1.01
Ifna2
KLA  ATP  ATP+KLA
 NM_010503 interferon alpha 2 (Ifna2), mRNA [NM_010503] KLA 1.08 1.06 1.07 1.06 .98 1.02 1.05
ATP .94 1.06 1.11 1.30 1.24 1.25 1.21
KLA/ATP 1.03 1.20 1.19 1.35 1.52 1.60 1.18
Ifna4
KLA  ATP  ATP+KLA
 NM_010504 interferon alpha 4 (Ifna4), mRNA [NM_010504] KLA .99 1.04 1.05 .97 1.00 .96 .99
ATP 1.01 .96 .98 1.01 1.00 1.00 .97
KLA/ATP 1.10 1.09 1.05 1.04 1.01 .97 1.01
Ifna5
KLA  ATP  ATP+KLA
 NM_010505 interferon alpha 5 (Ifna5), mRNA [NM_010505] KLA 1.15 1.23 1.51 1.26 1.03 1.06 1.05
ATP .99 .94 1.11 1.00 1.09 1.07 1.03
KLA/ATP 1.12 1.29 1.46 1.47 1.24 1.32 1.03
Ifna9
KLA  ATP  ATP+KLA
 NM_010507 interferon alpha 9 (Ifna9), mRNA [NM_010507] KLA 1.05 1.09 1.20 1.06 1.08 1.06 1.02
ATP .99 1.08 1.18 1.21 1.09 .99 .97
KLA/ATP 1.09 1.23 1.19 1.24 1.18 1.16 1.04
Ifnab
KLA  ATP  ATP+KLA
 BC116864 interferon alpha B, mRNA (cDNA clone MGC:151241 IMAGE:40126183), complete cds [BC116864] KLA 1.20 1.33 1.29 1.30 1.20 1.20 1.08
ATP .99 .99 1.00 1.25 1.13 1.19 1.04
KLA/ATP 1.30 1.39 1.44 1.48 1.49 1.54 1.22
Ifnb1
KLA  ATP  ATP+KLA
 NM_010510 interferon beta 1, fibroblast (Ifnb1), mRNA [NM_010510] KLA 49.82 46.57 34.05 16.05 5.94 7.31 8.49
ATP .99 1.02 1.89 4.78 6.31 4.44 1.79
KLA/ATP 49.22 61.83 134.08 144.05 110.96 31.78 11.24
Ifne1
KLA  ATP  ATP+KLA
 NM_177348 interferon epsilon 1 (Ifne1), mRNA [NM_177348] KLA .99 1.04 1.00 1.00 1.02 .96 .90
ATP .93 .96 1.00 1.06 .96 1.07 .96
KLA/ATP 1.07 1.01 1.02 1.01 .89 .95 1.04
Ifnk
KLA  ATP  ATP+KLA
 NM_199157 interferon kappa (Ifnk), mRNA [NM_199157] KLA 1.04 1.03 1.05 1.06 1.04 1.05 1.04
ATP 1.04 1.00 .98 1.05 .98 1.09 1.03
KLA/ATP 1.10 1.03 1.01 1.02 .95 1.03 1.01
Ikbkb
KLA  ATP  ATP+KLA
 NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbke
KLA  ATP  ATP+KLA
 NM_019777 inhibitor of kappaB kinase epsilon (Ikbke), mRNA [NM_019777] KLA 6.03 5.91 6.38 6.89 7.05 6.70 4.74
ATP 1.02 1.11 .82 1.16 1.18 2.08 1.90
KLA/ATP 6.04 6.71 5.69 5.30 2.49 2.33 5.43
Ikbkg
KLA  ATP  ATP+KLA
 AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
 NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
 NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Il12a
KLA  ATP  ATP+KLA
 NM_008351 interleukin 12a (Il12a), mRNA [NM_008351] KLA 2.37 2.47 2.17 1.49 1.46 1.12 1.20
ATP 1.01 .97 1.12 1.07 1.02 1.07 1.06
KLA/ATP 2.01 2.76 2.54 1.70 1.08 1.10 1.27
Il12b
KLA  ATP  ATP+KLA
 NM_008352 interleukin 12b (Il12b), mRNA [NM_008352] KLA 194.79 211.32 198.97 173.01 142.24 40.28 3.10
ATP 1.05 1.10 1.59 1.99 2.71 2.72 1.52
KLA/ATP 191.27 223.23 280.10 224.29 183.03 68.43 10.69
Irf3
KLA  ATP  ATP+KLA
 ENSMUST00000107835 ens|Interferon regulatory factor 3 (IRF-3). [Source:Uniprot/SWISSPROT;Acc:P70671] [ENSMUST00000107835] KLA .55 .56 .60 .72 .88 .88 .98
ATP .77 .58 .50 .46 .80 .97 1.03
KLA/ATP .51 .46 .49 .53 .92 .85 .79
Irf3
KLA  ATP  ATP+KLA
 NM_016849 interferon regulatory factor 3 (Irf3), mRNA [NM_016849] KLA .79 .75 .71 .83 .88 1.07 .99
ATP .92 .84 .88 .61 .54 1.27 1.22
KLA/ATP .78 .78 .75 .58 .70 1.13 1.38
Irf7
KLA  ATP  ATP+KLA
 NM_016850 interferon regulatory factor 7 (Irf7), mRNA [NM_016850] KLA 4.90 4.72 5.85 5.82 7.67 10.64 15.44
ATP 1.14 1.10 .86 1.18 .96 2.46 12.17
KLA/ATP 5.41 5.22 4.15 6.29 5.31 9.74 29.08
Isg15
KLA  ATP  ATP+KLA
 NM_015783 ISG15 ubiquitin-like modifier (Isg15), mRNA [NM_015783] KLA 12.78 12.48 11.57 12.68 13.24 16.73 14.82
ATP .93 .94 1.24 1.46 2.53 13.04 16.55
KLA/ATP 11.94 13.20 14.20 16.01 21.40 25.56 32.80
Map3k1
KLA  ATP  ATP+KLA
 NM_011945 mitogen-activated protein kinase kinase kinase 1 (Map3k1), mRNA [NM_011945] KLA .30 .25 .37 .56 .68 1.07 .85
ATP .88 .86 1.26 1.04 1.07 .77 .78
KLA/ATP .28 .24 .59 .99 1.49 .97 1.24
Map3k7
KLA  ATP  ATP+KLA
 NM_172688 mitogen-activated protein kinase kinase kinase 7 (Map3k7), mRNA [NM_172688] KLA 1.48 1.49 1.51 1.24 1.21 1.19 1.61
ATP 1.10 1.16 1.03 1.03 1.12 1.61 1.61
KLA/ATP 1.43 1.56 1.05 1.15 .85 1.48 1.76
Mapk10
KLA  ATP  ATP+KLA
 AK076990 adult male testis cDNA, RIKEN full-length enriched library, clone:4930597C01 product:mitogen activated protein kinase 10, full insert sequence. [AK076990] KLA 1.03 1.05 .98 1.04 .94 .95 1.02
ATP 1.00 .99 1.06 .97 1.01 .96 .99
KLA/ATP 1.07 1.01 .95 1.05 .82 .95 .87
Mapk10
KLA  ATP  ATP+KLA
 NM_009158 mitogen-activated protein kinase 10 (Mapk10), transcript variant 1, mRNA [NM_009158] KLA .95 1.00 .97 1.01 .99 1.01 .95
ATP 1.01 1.02 .98 1.01 1.04 1.01 .99
KLA/ATP 1.05 .99 1.01 .98 .92 .97 .98
Mapk11
KLA  ATP  ATP+KLA
 NM_011161 mitogen-activated protein kinase 11 (Mapk11), mRNA [NM_011161] KLA 1.28 1.30 1.41 1.46 1.58 1.29 .98
ATP .96 .95 .89 .82 .79 1.09 .85
KLA/ATP 1.44 1.42 1.32 1.23 1.23 .74 .66
Mapk12
KLA  ATP  ATP+KLA
 NM_013871 mitogen-activated protein kinase 12 (Mapk12), mRNA [NM_013871] KLA .94 .86 .87 .81 .77 .68 .49
ATP .97 .83 .92 .90 .86 .90 .51
KLA/ATP .91 .89 .88 .85 1.12 1.14 .53
Mapk13
KLA  ATP  ATP+KLA
 NM_011950 mitogen-activated protein kinase 13 (Mapk13), mRNA [NM_011950] KLA 1.22 1.21 1.35 1.26 1.24 1.13 1.01
ATP 1.08 1.00 1.20 1.20 1.13 1.22 1.39
KLA/ATP 1.22 1.27 1.30 1.30 1.21 1.11 1.47
Mapk14
KLA  ATP  ATP+KLA
 NM_011951 mitogen-activated protein kinase 14 (Mapk14), mRNA [NM_011951] KLA .70 .70 .62 .54 .67 .88 1.11
ATP 1.03 .98 .87 .69 .48 .78 .66
KLA/ATP .74 .68 .52 .46 .38 .45 .62
Mapk8
KLA  ATP  ATP+KLA
 AK162915 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330031O19 product:mitogen activated protein kinase 8, full insert sequence [AK162915] KLA .94 .86 .80 .83 .77 .85 .83
ATP 1.08 1.12 .94 .80 .83 .71 .75
KLA/ATP .83 .81 .80 .74 .74 .75 .67
Mapk8
KLA  ATP  ATP+KLA
 AK163829 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130070A06 product:mitogen activated protein kinase 8, full insert sequence [AK163829] KLA .65 .61 .66 .70 .90 1.02 1.03
ATP .99 .94 1.68 1.44 1.75 1.84 1.10
KLA/ATP .63 .67 1.11 1.00 2.01 1.68 1.15
Mapk8
KLA  ATP  ATP+KLA
 NM_016700 mitogen-activated protein kinase 8 (Mapk8), mRNA [NM_016700] KLA .96 1.00 .94 .96 .94 .99 1.04
ATP 1.01 1.05 1.01 .99 1.03 .98 1.02
KLA/ATP .96 .97 .96 .97 .93 .94 .96
Mapk9
KLA  ATP  ATP+KLA
 NM_016961 mitogen-activated protein kinase 9 (Mapk9), transcript variant 2, mRNA [NM_016961] KLA 1.28 1.37 1.59 1.60 1.61 1.43 1.38
ATP 1.03 .99 .74 .71 .79 1.20 1.01
KLA/ATP 1.53 1.30 1.07 .99 .83 1.10 1.40
Mapk9
KLA  ATP  ATP+KLA
 NM_207692 mitogen-activated protein kinase 9 (Mapk9), transcript variant 1, mRNA [NM_207692] KLA 1.39 1.53 1.69 1.69 1.55 1.44 1.51
ATP .95 .92 .75 .85 .70 1.46 1.17
KLA/ATP 1.37 1.35 .99 1.18 .91 1.22 1.62
Mm.27970
KLA  ATP  ATP+KLA
 13994135 Unknown KLA 1.06 1.11 1.16 1.07 1.11 1.08 .95
ATP 1.02 1.09 1.05 1.05 .94 1.16 1.32
KLA/ATP 1.10 1.19 1.11 1.04 1.08 1.02 1.33
Mm.37708
7
KLA  ATP  ATP+KLA
 158631169 Unknown KLA .98 .98 1.06 1.06 .91 .97 1.04
ATP 1.00 1.07 1.01 1.06 1.09 .99 1.02
KLA/ATP 1.08 1.06 1.16 1.11 1.16 1.12 1.04
Mm.46002
4
KLA  ATP  ATP+KLA
 38348245 Unknown KLA 1.22 1.25 1.25 1.19 1.22 1.47 1.14
ATP 1.03 .94 1.01 1.01 2.67 2.31 1.37
KLA/ATP 1.35 1.19 1.27 1.22 1.99 1.83 1.45
Mm.5126
KLA  ATP  ATP+KLA
 158508678 Unknown KLA .70 .71 .73 .79 .87 1.11 1.25
ATP 1.22 1.37 1.08 1.54 1.38 1.01 1.26
KLA/ATP .85 .83 .75 .90 1.12 .96 1.17
Mm.57127
KLA  ATP  ATP+KLA
 117168292 Unknown KLA 1.20 1.25 1.28 1.18 1.14 1.13 1.12
ATP .98 .95 1.11 1.06 1.05 1.05 1.09
KLA/ATP 1.22 1.24 1.48 1.55 1.40 1.21 1.07
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkbia
KLA  ATP  ATP+KLA
 NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Nfkbib
KLA  ATP  ATP+KLA
 NM_010908 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (Nfkbib), mRNA [NM_010908] KLA 4.63 4.69 4.36 4.27 4.23 2.52 2.17
ATP 1.11 1.22 1.55 4.23 4.93 3.66 1.76
KLA/ATP 4.71 5.41 4.58 7.08 6.20 4.73 4.11
Nlrx1
KLA  ATP  ATP+KLA
 NM_178420 NLR family member X1 (Nlrx1), mRNA [NM_178420] KLA .68 .69 .68 .71 .80 1.07 1.29
ATP 1.03 1.08 .92 .92 .50 .63 1.02
KLA/ATP .70 .69 .66 .69 .54 .68 1.19
Otud5
KLA  ATP  ATP+KLA
 AK169921 NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630004F08 product:SI:bZ30I22.1 (Novel protein similar to human FLJ12550) (Fragment) homolog [Brachydanio rerio], full insert sequence [AK169921] KLA 1.42 1.58 1.72 1.51 1.66 1.27 1.22
ATP 1.03 1.22 1.01 1.08 .88 .88 .83
KLA/ATP 1.65 1.64 1.11 1.54 .97 .83 .79
Otud5
KLA  ATP  ATP+KLA
 NM_138604 OTU domain containing 5 (Otud5), mRNA [NM_138604] KLA 2.51 2.33 2.34 2.46 2.47 1.83 1.48
ATP 1.15 1.14 1.18 1.20 1.20 1.82 1.31
KLA/ATP 2.22 2.55 3.09 3.00 2.07 1.93 2.46
Pin1
KLA  ATP  ATP+KLA
 NM_023371 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1), mRNA [NM_023371] KLA .90 .94 .84 .87 .84 .95 .98
ATP .96 1.01 .99 1.00 .84 .90 .94
KLA/ATP .86 .90 .88 .87 .86 .83 .89
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Ripk1
KLA  ATP  ATP+KLA
 NM_009068 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), mRNA [NM_009068] KLA 1.32 1.33 1.50 1.09 1.00 1.11 1.13
ATP .98 .94 .60 .59 1.35 1.56 1.45
KLA/ATP 1.48 1.30 1.01 1.05 1.36 1.53 1.37
Rnf125
KLA  ATP  ATP+KLA
 NM_026301 ring finger protein 125 (Rnf125), mRNA [NM_026301] KLA 1.67 1.66 1.63 1.30 .95 .88 .85
ATP .96 .99 1.00 1.02 1.96 2.56 .99
KLA/ATP 1.76 1.72 1.46 1.42 1.24 1.20 .97
Tank
KLA  ATP  ATP+KLA
 AK156658 activated spleen cDNA, RIKEN full-length enriched library, clone:F830035J19 product:unclassifiable, full insert sequence. [AK156658] KLA 1.75 1.65 1.75 1.45 1.47 1.33 1.27
ATP 1.08 1.13 2.53 2.18 1.48 1.11 1.02
KLA/ATP 1.85 1.74 2.43 1.83 1.32 1.33 1.15
Tank
KLA  ATP  ATP+KLA
 NM_011529 TRAF family member-associated Nf-kappa B activator (Tank), mRNA [NM_011529] KLA 5.37 5.66 5.94 5.10 4.85 4.25 3.58
ATP .89 .95 1.15 2.40 3.41 2.30 1.99
KLA/ATP 4.75 5.37 5.10 5.73 4.73 4.00 4.01
Tbk1
KLA  ATP  ATP+KLA
 NM_019786 TANK-binding kinase 1 (Tbk1), mRNA [NM_019786] KLA 2.55 2.76 3.22 2.67 2.56 2.29 1.96
ATP 1.13 1.30 1.12 1.07 1.29 1.41 1.40
KLA/ATP 2.84 3.17 2.58 2.43 1.70 2.15 2.37
Tbkbp1
KLA  ATP  ATP+KLA
 NM_198100 TBK1 binding protein 1 (Tbkbp1), mRNA [NM_198100] KLA .72 .78 .82 .74 .80 .73 1.02
ATP 1.09 .96 .70 .81 1.07 1.01 1.59
KLA/ATP .92 .76 .53 .61 1.19 .90 1.43
Tmem173
KLA  ATP  ATP+KLA
 XM_900126 gb|PREDICTED: Mus musculus RIKEN cDNA 2610307O08 gene, transcript variant 5 (2610307O08Rik), mRNA [XM_900126] KLA 1.39 1.28 1.52 1.40 1.12 .69 .64
ATP 1.10 .92 1.09 .89 .76 .67 .90
KLA/ATP 1.39 1.43 2.00 1.59 1.56 .94 .90
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Tradd
KLA  ATP  ATP+KLA
 NM_001033161 TNFRSF1A-associated via death domain (Tradd), mRNA [NM_001033161] KLA .77 .71 .82 .89 .89 1.11 1.06
ATP 1.00 .90 1.01 .73 .59 1.34 1.50
KLA/ATP .79 .73 .83 .63 .72 1.11 1.73
Traf2
KLA  ATP  ATP+KLA
 NM_009422 Tnf receptor-associated factor 2 (Traf2), mRNA [NM_009422] KLA 3.38 3.62 3.49 3.36 3.49 3.39 2.68
ATP .97 1.04 1.00 1.10 1.54 2.40 1.55
KLA/ATP 3.38 3.16 2.93 2.74 2.67 3.11 4.70
Traf3
KLA  ATP  ATP+KLA
 NM_011632 Tnf receptor-associated factor 3 (Traf3), transcript variant 1, mRNA [NM_011632] KLA .52 .49 .51 .49 .80 .98 1.22
ATP .93 .92 .95 1.13 2.70 1.80 1.42
KLA/ATP .56 .50 .49 1.07 2.94 1.92 1.65
Traf6
KLA  ATP  ATP+KLA
 NM_009424 Tnf receptor-associated factor 6 (Traf6), mRNA [NM_009424] KLA 1.19 1.28 1.34 1.20 1.23 1.23 1.28
ATP 1.06 1.12 .92 1.15 2.46 1.84 1.40
KLA/ATP 1.32 1.37 .89 1.16 1.45 1.49 1.46
Trim25
KLA  ATP  ATP+KLA
 NM_009546 tripartite motif-containing 25 (Trim25), mRNA [NM_009546] KLA 3.93 4.08 4.13 3.67 3.19 3.12 3.13
ATP 1.02 1.00 .92 1.22 2.80 3.73 3.72
KLA/ATP 4.17 4.41 4.23 4.23 5.38 5.22 7.68