Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Melanogenesis (mmu04916)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
a
KLA  ATP  ATP+KLA
 NM_015770 nonagouti (a), mRNA [NM_015770] KLA 1.03 1.03 1.03 1.05 1.10 1.09 1.05
ATP 1.01 1.03 1.00 .96 1.00 1.00 1.00
KLA/ATP 1.02 1.01 1.03 1.01 .99 1.00 1.02
Adcy1
KLA  ATP  ATP+KLA
 BC050125 adenylate cyclase 1, mRNA (cDNA clone IMAGE:30015692). [BC050125] KLA 1.05 1.03 .98 1.04 1.05 1.09 1.10
ATP .90 1.02 .99 .97 1.03 .95 1.01
KLA/ATP .99 1.04 .90 .98 .98 1.00 1.03
Adcy1
KLA  ATP  ATP+KLA
 NM_009622 adenylate cyclase 1 (Adcy1), mRNA [NM_009622] KLA 1.07 1.02 1.06 1.07 1.03 1.02 1.01
ATP 1.02 1.04 1.00 .99 .99 .95 .97
KLA/ATP .97 1.05 1.02 1.05 1.01 .98 1.05
Adcy2
KLA  ATP  ATP+KLA
 NM_153534 adenylate cyclase 2 (Adcy2), mRNA [NM_153534] KLA .79 .82 .83 .73 .61 .66 .90
ATP 1.10 1.09 1.02 1.04 .88 .58 .53
KLA/ATP .84 .87 .77 .75 .68 .60 .43
Adcy3
KLA  ATP  ATP+KLA
 NM_138305 adenylate cyclase 3 (Adcy3), mRNA [NM_138305] KLA .84 .84 .83 .78 .66 .55 .49
ATP 1.09 1.05 .89 1.02 .84 .62 1.52
KLA/ATP .93 .87 .75 .85 .66 .83 .77
Adcy4
KLA  ATP  ATP+KLA
 NM_080435 adenylate cyclase 4 (Adcy4), mRNA [NM_080435] KLA 1.05 1.07 .96 1.00 1.04 1.05 1.05
ATP 1.02 1.05 1.02 1.48 1.37 1.08 1.09
KLA/ATP 1.00 1.05 .91 1.19 1.35 1.27 1.08
Adcy5
KLA  ATP  ATP+KLA
 NM_001012765 adenylate cyclase 5 (Adcy5), mRNA [NM_001012765] KLA 1.06 1.00 .97 1.01 1.03 .95 .93
ATP .95 1.08 1.08 1.07 .97 1.03 .97
KLA/ATP .97 .92 1.04 .99 .91 .96 1.04
Adcy6
KLA  ATP  ATP+KLA
 NM_007405 adenylate cyclase 6 (Adcy6), mRNA [NM_007405] KLA 1.10 1.16 1.16 1.09 1.08 1.06 .99
ATP 1.05 .97 1.08 1.12 1.08 1.08 1.04
KLA/ATP 1.14 1.20 1.29 1.30 1.25 1.11 1.07
Adcy7
KLA  ATP  ATP+KLA
 NM_001037724 adenylate cyclase 7 (Adcy7), transcript variant 3, mRNA [NM_001037724] KLA .43 .39 .35 .32 .45 .72 .84
ATP .90 .84 .62 .41 .53 .42 .94
KLA/ATP .39 .34 .23 .17 .41 .34 .67
Adcy7
KLA  ATP  ATP+KLA
 NM_007406 adenylate cyclase 7 (Adcy7), transcript variant 1, mRNA [NM_007406] KLA .51 .52 .48 .41 .59 .81 .99
ATP 1.01 1.02 .62 .52 .53 .38 .98
KLA/ATP .53 .48 .30 .27 .42 .36 .65
Adcy8
KLA  ATP  ATP+KLA
 NM_009623 adenylate cyclase 8 (Adcy8), mRNA [NM_009623] KLA 1.00 1.00 1.07 .97 1.04 .98 1.02
ATP 1.04 1.05 1.14 1.03 .99 1.00 .97
KLA/ATP 1.05 1.04 1.00 1.03 .98 .94 .96
Adcy9
KLA  ATP  ATP+KLA
 NM_009624 adenylate cyclase 9 (Adcy9), mRNA [NM_009624] KLA .18 .15 .13 .15 .17 .19 .33
ATP 1.33 1.16 .97 .98 .62 .56 .86
KLA/ATP .19 .16 .17 .18 .20 .25 .38
AK019932
KLA  ATP  ATP+KLA
 AK019932 adult male pituitary gland cDNA, RIKEN full-length enriched library, clone:5330434N09 product:inferred: transmembrane receptor frizzled 5 {Mus musculus}, full insert sequence [AK019932] KLA .99 .94 .97 .98 .96 .99 1.03
ATP 1.02 1.07 1.02 .97 1.00 .98 .93
KLA/ATP .93 .99 .91 1.04 1.02 1.01 1.00
Calm1
KLA  ATP  ATP+KLA
 NM_009790 calmodulin 1 (Calm1), mRNA [NM_009790] KLA 1.20 1.26 1.30 1.06 1.16 1.09 1.18
ATP 1.07 1.20 1.00 1.29 .99 .64 .58
KLA/ATP 1.31 1.31 .93 1.31 .97 .83 .59
Calm2
KLA  ATP  ATP+KLA
 NM_007589 calmodulin 2 (Calm2), mRNA [NM_007589] KLA .79 .81 .71 .67 .54 .45 .64
ATP .99 1.03 1.04 .93 .82 .52 .76
KLA/ATP .76 .78 .76 .77 .73 .47 .42
Calm3
KLA  ATP  ATP+KLA
 NM_007590 calmodulin 3 (Calm3), mRNA [NM_007590] KLA .95 .96 .93 1.03 1.05 1.08 1.00
ATP .93 .96 .99 .97 .93 .84 .72
KLA/ATP .89 .93 .90 .91 1.02 .98 .70
Calm4
KLA  ATP  ATP+KLA
 NM_020036 calmodulin 4 (Calm4), mRNA [NM_020036] KLA 1.02 .96 1.05 1.00 .99 1.00 1.01
ATP 1.10 1.05 1.03 1.01 .94 .98 .98
KLA/ATP .99 1.12 1.01 1.03 .98 1.07 1.02
Calm5
KLA  ATP  ATP+KLA
 NM_001008706 calmodulin 5 (Calm5), mRNA [NM_001008706] KLA 1.02 1.11 .99 .98 1.07 1.01 1.09
ATP 1.07 1.05 1.04 1.04 1.01 1.04 .99
KLA/ATP 1.00 1.00 .97 1.07 1.00 1.07 .98
Calml3
KLA  ATP  ATP+KLA
 NM_027416 calmodulin-like 3 (Calml3), mRNA [NM_027416] KLA 1.01 .95 1.05 .91 1.01 .98 .89
ATP .91 1.05 1.04 1.01 .93 1.07 .99
KLA/ATP 1.01 .96 .97 .96 .97 .92 .99
Camk2a
KLA  ATP  ATP+KLA
 NM_177407 calcium/calmodulin-dependent protein kinase II alpha (Camk2a), transcript variant 2, mRNA [NM_177407] KLA .98 .97 .98 .95 .97 1.02 .97
ATP .98 1.11 1.02 .89 .94 .89 .82
KLA/ATP .99 .95 1.02 .88 .88 .87 .87
Camk2b
KLA  ATP  ATP+KLA
 NM_007595 calcium/calmodulin-dependent protein kinase II, beta (Camk2b), mRNA [NM_007595] KLA 1.09 1.28 1.42 1.41 1.37 1.24 .68
ATP .94 .87 .95 .91 .67 .44 .48
KLA/ATP 1.16 1.24 1.40 1.13 1.14 .81 .49
Camk2d
KLA  ATP  ATP+KLA
 AK032524 adult male olfactory brain cDNA, RIKEN full-length enriched library, clone:6430579P05 product:calcium/calmodulin-dependent protein kinase II, delta, full insert sequence. [AK032524] KLA 1.31 1.45 1.42 1.21 1.34 1.18 1.16
ATP 1.04 1.29 1.39 1.24 .94 .91 1.22
KLA/ATP 1.46 1.64 1.42 1.24 1.00 .93 1.10
Camk2d
KLA  ATP  ATP+KLA
 NM_001025439 calcium/calmodulin-dependent protein kinase II, delta (Camk2d), transcript variant 1, mRNA [NM_001025439] KLA 1.76 1.75 1.72 1.89 1.47 1.55 1.24
ATP 1.06 1.06 .93 1.01 1.22 .98 2.28
KLA/ATP 1.84 1.78 1.40 1.57 1.07 .60 1.97
Camk2g
KLA  ATP  ATP+KLA
 NM_178597 calcium/calmodulin-dependent protein kinase II gamma (Camk2g), transcript variant 1, mRNA [NM_178597] KLA .23 .24 .23 .44 .70 .73 .70
ATP .91 .85 1.07 .86 .58 .59 .95
KLA/ATP .22 .20 .35 .25 .54 .59 .71
Creb1
KLA  ATP  ATP+KLA
 NM_009952 cAMP responsive element binding protein 1 (Creb1), transcript variant B, mRNA [NM_009952] KLA 1.42 1.33 1.16 .99 .83 .97 .92
ATP .92 .91 1.18 1.38 1.51 1.02 .75
KLA/ATP 1.34 1.31 1.49 1.37 1.71 1.05 .93
Creb3
KLA  ATP  ATP+KLA
 NM_013497 cAMP responsive element binding protein 3 (Creb3), mRNA [NM_013497] KLA 1.21 1.21 1.23 1.53 1.77 1.77 1.31
ATP 1.02 1.03 .99 1.05 .82 .83 1.48
KLA/ATP 1.15 1.18 1.20 1.26 1.13 1.15 1.86
Creb3l1
KLA  ATP  ATP+KLA
 NM_011957 cAMP responsive element binding protein 3-like 1 (Creb3l1), mRNA [NM_011957] KLA 1.18 1.17 1.53 1.28 1.22 1.11 1.23
ATP 1.01 1.09 .98 1.17 1.22 1.01 1.15
KLA/ATP 1.22 1.29 1.08 1.34 1.14 1.36 1.12
Creb3l2
KLA  ATP  ATP+KLA
 AK082964 12 days embryo spinal cord cDNA, RIKEN full-length enriched library, clone:C530025K05 product:unclassifiable, full insert sequence [AK082964] KLA .44 .38 .37 .40 .45 .42 .47
ATP .90 .78 1.22 .79 .54 .46 .44
KLA/ATP .41 .41 .49 .43 .50 .51 .23
Creb3l2
KLA  ATP  ATP+KLA
 NM_178661 cAMP responsive element binding protein 3-like 2 (Creb3l2), mRNA [NM_178661] KLA .98 .87 .76 .98 1.03 .87 1.12
ATP 1.20 1.18 1.50 1.35 .86 1.32 1.50
KLA/ATP .98 1.04 1.15 1.05 .79 1.27 1.25
Creb3l3
KLA  ATP  ATP+KLA
 NM_145365 cAMP responsive element binding protein 3-like 3 (Creb3l3), mRNA [NM_145365] KLA .66 .75 .65 .85 1.04 1.44 1.73
ATP 1.02 .98 .97 1.09 .85 .69 1.11
KLA/ATP .70 .66 .71 .83 .80 .85 1.05
Creb3l4
KLA  ATP  ATP+KLA
 NM_030080 cAMP responsive element binding protein 3-like 4 (Creb3l4), mRNA [NM_030080] KLA 1.55 1.42 1.51 1.73 1.76 2.54 1.38
ATP 1.07 .81 .89 1.08 .94 1.08 1.08
KLA/ATP 1.44 1.38 1.44 1.25 1.30 1.26 2.24
Crebbp
KLA  ATP  ATP+KLA
 AK048818 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230072N21 product:hypothetical protein, full insert sequence [AK048818] KLA 1.44 1.19 1.26 1.25 1.25 1.36 1.24
ATP .98 .90 1.04 1.11 1.95 2.72 1.51
KLA/ATP 1.17 1.27 1.45 1.28 1.98 2.80 2.52
Crebbp
KLA  ATP  ATP+KLA
 NM_001025432 CREB binding protein (Crebbp), mRNA [NM_001025432] KLA .97 1.01 .98 1.06 1.05 .99 1.07
ATP 1.07 1.05 .96 1.01 1.15 1.14 1.00
KLA/ATP 1.01 .97 .97 1.00 1.03 1.23 1.13
Crebbp
KLA  ATP  ATP+KLA
 S66385 gb|CREB-binding protein [mice, brain, mRNA Partial, 7326 nt]. [S66385] KLA 1.00 .98 1.08 .98 1.04 1.07 1.08
ATP .99 .98 .99 1.09 1.13 1.08 1.05
KLA/ATP 1.06 1.00 1.05 1.03 1.02 1.14 1.11
Ctnnb1
KLA  ATP  ATP+KLA
 AK020013 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830416C23 product:catenin beta, full insert sequence. [AK020013] KLA 1.06 1.15 1.00 1.06 1.27 1.14 1.03
ATP .85 .57 1.74 3.36 4.13 2.19 1.55
KLA/ATP 1.12 .87 2.47 3.61 3.79 2.21 2.06
Ctnnb1
KLA  ATP  ATP+KLA
 NM_007614 catenin (cadherin associated protein), beta 1 (Ctnnb1), mRNA [NM_007614] KLA 1.02 1.07 1.13 1.03 1.04 .93 .96
ATP 1.12 1.14 .75 .77 .73 .72 1.52
KLA/ATP 1.18 1.17 .77 .85 .60 .59 1.35
Dct
KLA  ATP  ATP+KLA
 NM_010024 dopachrome tautomerase (Dct), mRNA [NM_010024] KLA 1.01 .97 .97 1.01 1.00 .99 1.02
ATP .97 1.00 1.00 1.00 .98 .98 1.01
KLA/ATP .97 1.01 1.07 1.02 .97 .95 1.04
Dvl1
KLA  ATP  ATP+KLA
 NM_010091 dishevelled, dsh homolog 1 (Drosophila) (Dvl1), mRNA [NM_010091] KLA .93 .91 .86 .74 .70 .80 1.05
ATP 1.01 1.01 .91 .91 .98 1.10 1.02
KLA/ATP 1.00 .93 .79 .82 .81 .85 1.06
Dvl2
KLA  ATP  ATP+KLA
 NM_007888 dishevelled 2, dsh homolog (Drosophila) (Dvl2), mRNA [NM_007888] KLA .49 .52 .48 .53 .52 .67 .75
ATP 1.08 1.08 .76 .93 1.47 .89 1.20
KLA/ATP .57 .47 .40 .61 1.37 .91 .92
Dvl3
KLA  ATP  ATP+KLA
 NM_007889 dishevelled 3, dsh homolog (Drosophila) (Dvl3), mRNA [NM_007889] KLA 1.08 1.09 1.05 1.18 1.11 1.10 1.11
ATP 1.00 1.01 1.05 1.05 .99 1.10 1.15
KLA/ATP 1.12 1.07 1.09 1.09 1.06 1.15 1.09
Edn1
KLA  ATP  ATP+KLA
 NM_010104 endothelin 1 (Edn1), mRNA [NM_010104] KLA 73.36 71.33 61.92 68.69 46.94 32.60 13.54
ATP 1.23 1.89 4.18 10.86 17.85 11.03 1.91
KLA/ATP 67.27 76.78 116.70 90.29 76.38 29.71 8.04
Ednrb
KLA  ATP  ATP+KLA
 NM_007904 endothelin receptor type B (Ednrb), mRNA [NM_007904] KLA 3.53 3.62 3.97 2.91 1.91 1.83 .88
ATP .97 .95 1.05 1.80 4.84 18.19 9.14
KLA/ATP 3.30 3.37 3.89 3.06 2.11 4.82 10.15
Ep300
KLA  ATP  ATP+KLA
 AK042627 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730011L11 product:P300 TRANSCRIPTION COACTIVATOR (FRAGMENT) homolog [Mus sp], full insert sequence. [AK042627] KLA 1.02 .95 .92 1.04 1.01 1.00 1.05
ATP 1.06 .89 .88 .89 1.00 .90 1.07
KLA/ATP 1.10 1.02 .87 .91 1.04 .97 .98
Ep300
KLA  ATP  ATP+KLA
 NM_177821 E1A binding protein p300 (Ep300), mRNA [NM_177821] KLA 1.61 1.26 1.57 1.38 1.78 1.41 1.40
ATP 1.34 1.60 1.11 1.08 1.16 1.05 1.15
KLA/ATP 1.86 1.94 1.18 1.56 1.71 1.42 2.05
Fzd1
KLA  ATP  ATP+KLA
 NM_021457 frizzled homolog 1 (Drosophila) (Fzd1), mRNA [NM_021457] KLA 15.53 16.47 14.36 11.40 6.80 2.73 2.49
ATP 1.01 1.02 1.39 2.05 6.43 10.47 1.41
KLA/ATP 12.71 14.30 14.99 14.06 9.72 9.90 8.10
Fzd10
KLA  ATP  ATP+KLA
 NM_175284 frizzled homolog 10 (Drosophila) (Fzd10), mRNA [NM_175284] KLA .99 .98 .99 1.03 1.03 1.02 .99
ATP .98 .98 .97 1.03 1.05 1.00 .96
KLA/ATP .96 .98 1.08 1.02 1.04 1.02 1.00
Fzd2
KLA  ATP  ATP+KLA
 NM_020510 frizzled homolog 2 (Drosophila) (Fzd2), mRNA [NM_020510] KLA .97 1.01 1.01 1.02 1.00 .96 .97
ATP 1.01 1.02 1.03 1.02 .97 1.03 .93
KLA/ATP 1.04 .98 .99 1.03 .99 1.03 .98
Fzd3
KLA  ATP  ATP+KLA
 NM_021458 frizzled homolog 3 (Drosophila) (Fzd3), mRNA [NM_021458] KLA 1.00 1.00 .99 1.04 1.02 1.06 1.07
ATP 1.00 1.00 .95 1.04 1.04 1.01 1.05
KLA/ATP .98 1.05 1.06 .99 1.02 1.00 1.03
Fzd4
KLA  ATP  ATP+KLA
 NM_008055 frizzled homolog 4 (Drosophila) (Fzd4), mRNA [NM_008055] KLA .96 .88 .91 .92 .82 .89 .84
ATP .97 .98 1.05 1.02 .93 .90 .96
KLA/ATP .82 .86 .97 .92 .88 .91 .92
Fzd5
KLA  ATP  ATP+KLA
 NM_022721 frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 1, mRNA [NM_022721] KLA 1.63 1.69 1.56 1.23 .91 1.01 .92
ATP 1.03 1.32 4.46 9.23 7.72 2.14 1.11
KLA/ATP 1.63 1.92 4.20 8.67 8.29 3.07 1.12
Fzd6
KLA  ATP  ATP+KLA
 NM_008056 frizzled homolog 6 (Drosophila) (Fzd6), mRNA [NM_008056] KLA .97 1.01 .96 .90 .87 .94 .98
ATP .98 .97 .98 .94 .95 1.09 .96
KLA/ATP .97 1.02 .94 .92 .90 1.02 1.00
Fzd7
KLA  ATP  ATP+KLA
 NM_008057 frizzled homolog 7 (Drosophila) (Fzd7), mRNA [NM_008057] KLA 1.50 1.68 1.53 1.31 1.13 1.00 .94
ATP 1.04 1.12 1.60 3.45 2.56 1.72 1.02
KLA/ATP 1.89 1.92 1.96 4.61 3.75 3.38 1.88
Fzd8
KLA  ATP  ATP+KLA
 AK034561 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430006K02 product:inferred: transmembrane receptor {Mus musculus}; frizzled homolog 8 (Drosophila) homolog {GNF expression}, KLA 1.00 .98 1.05 .98 .96 1.03 .94
ATP 1.00 .92 1.06 1.05 1.02 1.01 .98
KLA/ATP .99 1.06 .99 .94 .95 .99 1.03
Fzd8
KLA  ATP  ATP+KLA
 NM_008058 frizzled homolog 8 (Drosophila) (Fzd8), mRNA [NM_008058] KLA 1.09 1.15 1.07 1.05 1.03 1.05 .98
ATP 1.05 1.08 2.01 3.38 2.89 1.20 1.03
KLA/ATP 1.04 1.17 1.65 2.57 2.62 1.40 1.04
Fzd9
KLA  ATP  ATP+KLA
 NM_010246 frizzled homolog 9 (Drosophila) (Fzd9), mRNA [NM_010246] KLA 1.03 1.10 1.12 .96 .98 1.00 .94
ATP 1.00 1.00 1.03 1.06 1.07 1.14 .98
KLA/ATP 1.10 1.07 1.03 .84 1.11 .96 .98
Gnai1
KLA  ATP  ATP+KLA
 NM_010305 guanine nucleotide binding protein (G protein), alpha inhibiting 1 (Gnai1), mRNA [NM_010305] KLA .95 1.01 1.01 1.00 1.09 1.10 1.08
ATP 1.06 1.06 .99 1.15 1.02 .94 .99
KLA/ATP 1.02 1.04 .99 1.16 1.01 1.02 1.13
Gnai2
KLA  ATP  ATP+KLA
 NM_008138 guanine nucleotide binding protein (G protein), alpha inhibiting 2 (Gnai2), mRNA [NM_008138] KLA .74 .79 .82 .74 .91 .97 1.10
ATP 1.07 1.16 .78 1.12 .78 .48 .82
KLA/ATP .91 .81 .53 .80 .60 .68 .87
Gnai3
KLA  ATP  ATP+KLA
 NM_010306 guanine nucleotide binding protein (G protein), alpha inhibiting 3 (Gnai3), mRNA [NM_010306] KLA 1.23 1.24 1.14 1.06 .99 1.15 1.09
ATP .96 .93 .86 .64 1.34 2.02 1.35
KLA/ATP 1.20 1.24 .97 .76 1.21 1.62 1.17
Gnao1
KLA  ATP  ATP+KLA
 NM_001113384 guanine nucleotide binding protein, alpha O (Gnao1), transcript variant B, mRNA [NM_001113384] KLA .95 .98 1.03 1.00 1.02 1.02 .99
ATP .95 1.02 1.01 1.08 .99 .97 .95
KLA/ATP 1.05 1.04 1.10 .99 1.01 .98 1.03
Gnao1
KLA  ATP  ATP+KLA
 NM_010308 guanine nucleotide binding protein, alpha O (Gnao1), transcript variant A, mRNA [NM_010308] KLA .98 .96 1.00 .97 .96 .97 1.01
ATP 1.12 .99 1.05 .87 .97 1.02 1.01
KLA/ATP .93 1.00 .99 1.01 1.05 1.07 .98
Gnaq
KLA  ATP  ATP+KLA
 NM_008139 guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA [NM_008139] KLA .82 .82 .69 .64 .60 .55 .55
ATP 1.06 1.02 .87 .67 .50 .66 .57
KLA/ATP .82 .79 .66 .55 .41 .33 .48
Gnas
KLA  ATP  ATP+KLA
 AF107847 neuroendocrine-specific Golgi protein p55 isoform 1 (XLalphas) alternatively spliced mRNA, complete cds. [AF107847] KLA 1.04 .94 1.00 1.05 1.04 .98 1.00
ATP .98 .97 .96 1.00 .99 .98 1.02
KLA/ATP 1.04 1.02 .96 .95 1.01 .96 1.01
Gnas
KLA  ATP  ATP+KLA
 AK017423 10 days neonate head cDNA, RIKEN full-length enriched library, clone:5530400H20 product:novel noncoding RNA overlapping the exon 1A, 1 and 2 of Gnas, full insert sequence. [AK017423] KLA .85 1.08 .97 .92 1.05 1.03 1.08
ATP .99 1.30 2.11 1.73 1.23 1.01 1.02
KLA/ATP .96 1.06 1.58 1.34 1.29 1.05 .91
Gnas
KLA  ATP  ATP+KLA
 NM_001077510 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus (Gnas), transcript variant 8, mRNA [NM_001077510] KLA .99 1.03 .97 .91 1.03 .95 .97
ATP 1.04 1.19 1.15 1.61 1.24 .91 1.00
KLA/ATP 1.06 .97 1.01 1.46 1.04 .85 1.01
Gnas
KLA  ATP  ATP+KLA
 S49980 gb|stimulatory G protein alpha subunit {clone WC-16} [mice, whole cochlea, mRNA Partial, 356 nt]. [S49980] KLA .91 .88 1.03 .87 .90 .84 1.01
ATP 1.16 1.22 1.02 1.55 1.16 .80 .99
KLA/ATP 1.01 1.13 .86 1.12 .97 .85 1.08
Gsk3b
KLA  ATP  ATP+KLA
 NM_019827 glycogen synthase kinase 3 beta (Gsk3b), mRNA [NM_019827] KLA 1.06 1.03 1.11 1.01 1.26 1.28 1.26
ATP 1.18 1.27 1.15 2.07 2.37 2.32 1.67
KLA/ATP 1.15 1.21 .98 1.50 1.67 2.50 2.99
Hras1
KLA  ATP  ATP+KLA
 NM_008284 Harvey rat sarcoma virus oncogene 1 (Hras1), mRNA [NM_008284] KLA .79 .82 .77 .82 .94 1.03 1.07
ATP 1.01 .95 .69 .83 .79 1.12 1.15
KLA/ATP .84 .77 .61 .65 .82 1.00 1.05
Kit
KLA  ATP  ATP+KLA
 Y00864 gb|Mouse c-kit mRNA. [Y00864] KLA .88 .86 .83 .76 .75 .73 .87
ATP 1.06 1.07 1.03 1.04 3.95 1.93 1.25
KLA/ATP .87 .87 .89 .89 1.06 1.08 .91
Kitl
KLA  ATP  ATP+KLA
 NM_013598 kit ligand (Kitl), mRNA [NM_013598] KLA .49 .46 .43 .38 .23 .35 .46
ATP .89 .85 .79 .91 1.14 1.30 .86
KLA/ATP .48 .43 .49 .96 1.59 1.38 .95
Kras
KLA  ATP  ATP+KLA
 NM_021284 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras), mRNA [NM_021284] KLA .53 .49 .40 .42 .49 .95 1.05
ATP .98 1.01 1.16 1.17 1.39 1.29 1.74
KLA/ATP .50 .47 .50 .56 1.00 1.24 1.58
Lef1
KLA  ATP  ATP+KLA
 NM_010703 lymphoid enhancer binding factor 1 (Lef1), mRNA [NM_010703] KLA 1.00 1.05 1.00 1.05 1.01 1.07 1.07
ATP .96 .98 1.03 1.09 .99 1.04 1.00
KLA/ATP 1.02 .98 .95 1.08 1.02 1.16 1.08
Map2k1
KLA  ATP  ATP+KLA
 NM_008927 mitogen-activated protein kinase kinase 1 (Map2k1), mRNA [NM_008927] KLA 1.82 2.00 2.31 2.03 2.51 2.20 1.51
ATP .99 1.14 .81 .87 .90 1.57 1.11
KLA/ATP 1.90 2.03 1.50 1.93 1.63 2.03 2.06
Map2k2
KLA  ATP  ATP+KLA
 NM_023138 mitogen-activated protein kinase kinase 2 (Map2k2), mRNA [NM_023138] KLA .96 1.01 1.09 .99 1.11 1.15 1.42
ATP 1.07 1.05 .74 .86 1.04 1.16 1.21
KLA/ATP 1.14 1.03 .68 .78 .85 1.01 1.20
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mc1r
KLA  ATP  ATP+KLA
 NM_008559 melanocortin 1 receptor (Mc1r), mRNA [NM_008559] KLA 1.09 .97 1.02 1.04 .96 .99 .97
ATP 1.02 1.04 .96 1.06 .92 .96 1.03
KLA/ATP 1.04 1.09 .92 1.03 1.02 .98 1.01
Mitf
KLA  ATP  ATP+KLA
 NM_008601 microphthalmia-associated transcription factor (Mitf), transcript variant 2, mRNA [NM_008601] KLA 2.09 2.20 1.58 2.38 2.33 2.27 1.52
ATP .93 .99 1.15 1.87 1.18 .89 1.16
KLA/ATP 1.83 2.28 2.35 2.87 1.26 .81 1.63
Mm.13153
0
KLA  ATP  ATP+KLA
 161086915 Unknown KLA 1.00 1.07 1.14 1.08 .97 1.00 .93
ATP 1.04 .99 1.00 .95 .99 1.02 .90
KLA/ATP 1.08 1.18 1.14 1.16 1.04 1.06 1.08
Mm.21516
1
KLA  ATP  ATP+KLA
 141801906 Unknown KLA 1.08 1.09 1.10 1.08 1.09 1.05 1.12
ATP .95 .94 1.05 1.16 1.05 1.08 1.14
KLA/ATP 1.07 1.15 1.16 1.16 1.10 1.14 1.14
Mm.23812
7
KLA  ATP  ATP+KLA
 168823498 Unknown KLA 1.07 .97 1.04 1.05 1.02 .98 1.02
ATP .95 1.00 .98 1.01 .95 .93 .92
KLA/ATP .93 .98 .98 1.04 1.01 1.02 .98
Mm.24600
3
KLA  ATP  ATP+KLA
 161086914 Unknown KLA 10.04 10.23 11.14 8.37 5.02 2.48 2.15
ATP .96 1.08 1.11 1.79 4.88 8.01 1.29
KLA/ATP 9.96 11.13 9.87 10.92 7.51 7.35 6.26
Mm.41137
KLA  ATP  ATP+KLA
 148747308 Unknown KLA 1.03 1.00 .95 .92 1.04 .98 .96
ATP 1.02 .98 .98 .90 .95 .92 1.07
KLA/ATP .91 .89 1.01 .95 1.00 .96 .99
Mm.44160
1
KLA  ATP  ATP+KLA
 145966786 Unknown KLA 1.08 .94 1.01 .97 .79 .78 .71
ATP 1.09 .92 1.10 .75 .65 .92 .69
KLA/ATP 1.01 .92 1.16 .81 .69 .56 .63
Mm.4769
KLA  ATP  ATP+KLA
 31542830 Unknown KLA .93 .99 .86 .85 .75 .83 .80
ATP 1.01 1.00 .91 .83 .96 1.15 .84
KLA/ATP .95 .95 .92 .81 .85 1.12 .87
Mm.56964
KLA  ATP  ATP+KLA
 144227223 Unknown KLA .96 .99 1.00 .99 .97 1.01 1.05
ATP .99 .94 1.00 .94 .97 .99 .91
KLA/ATP 1.05 .97 1.02 .97 .91 1.00 1.02
Nras
KLA  ATP  ATP+KLA
 NM_010937 neuroblastoma ras oncogene (Nras), mRNA [NM_010937] KLA 1.20 1.22 1.27 1.20 1.09 .91 .84
ATP .98 .91 .69 .61 .59 .67 .78
KLA/ATP 1.22 1.14 .97 .79 .73 .61 .72
Plcb1
KLA  ATP  ATP+KLA
 AK129166 mRNA for mKIAA0581 protein [AK129166] KLA 1.02 .98 .91 .91 .92 .95 .89
ATP 1.03 1.02 1.02 1.01 .90 1.02 1.04
KLA/ATP .98 .97 .91 .93 .92 1.01 1.16
Plcb1
KLA  ATP  ATP+KLA
 NM_019677 phospholipase C, beta 1 (Plcb1), mRNA [NM_019677] KLA .99 .94 .95 .97 .93 .92 .91
ATP 1.00 .96 .99 .95 .99 1.03 .98
KLA/ATP .93 .96 .94 .93 .87 1.00 1.06
Plcb2
KLA  ATP  ATP+KLA
 NM_177568 phospholipase C, beta 2 (Plcb2), mRNA [NM_177568] KLA .70 .68 .64 .67 .65 .76 .88
ATP .95 .94 1.04 .94 .72 .57 1.19
KLA/ATP .69 .68 .72 .63 .65 .55 .70
Plcb3
KLA  ATP  ATP+KLA
 NM_008874 phospholipase C, beta 3 (Plcb3), mRNA [NM_008874] KLA 1.72 1.78 1.82 1.65 1.67 1.44 1.21
ATP .97 1.04 .81 .87 .78 .88 .94
KLA/ATP 1.69 1.89 1.44 1.66 1.12 .73 .93
Plcb4
KLA  ATP  ATP+KLA
 AK082509 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230058B11 product:unclassifiable, full insert sequence. [AK082509] KLA 1.06 1.03 .97 .98 1.02 1.01 .99
ATP .99 1.07 1.09 .95 .97 .97 1.02
KLA/ATP .98 1.00 1.03 .96 1.02 .91 .98
Plcb4
KLA  ATP  ATP+KLA
 NM_013829 phospholipase C, beta 4 (Plcb4), mRNA [NM_013829] KLA .88 .94 .81 .82 .81 .86 1.01
ATP 1.00 1.01 .92 .93 .88 .85 .89
KLA/ATP .97 .94 .78 .80 .78 .86 .97
Pomc
KLA  ATP  ATP+KLA
 NM_008895 pro-opiomelanocortin-alpha (Pomc), mRNA [NM_008895] KLA .94 .98 .99 1.06 1.09 1.45 1.61
ATP 1.11 1.02 1.19 1.14 .90 1.39 2.00
KLA/ATP 1.02 1.05 .94 1.20 1.14 1.53 2.62
Prkaca
KLA  ATP  ATP+KLA
 NM_008854 protein kinase, cAMP dependent, catalytic, alpha (Prkaca), mRNA [NM_008854] KLA .71 .74 .72 .70 .72 .84 .85
ATP 1.05 .98 .89 .92 .76 .60 1.02
KLA/ATP .79 .74 .55 .65 .60 .65 .93
Prkacb
KLA  ATP  ATP+KLA
 NM_011100 protein kinase, cAMP dependent, catalytic, beta (Prkacb), mRNA [NM_011100] KLA .69 .70 .66 .58 .51 .55 .59
ATP 1.02 1.19 .97 1.01 .69 .38 .56
KLA/ATP .72 .73 .57 .62 .47 .41 .45
Prkca
KLA  ATP  ATP+KLA
 NM_011101 protein kinase C, alpha (Prkca), mRNA [NM_011101] KLA 1.00 .96 .94 .95 .95 .89 .96
ATP 1.00 1.03 .91 .94 .82 .87 1.13
KLA/ATP 1.02 .95 .91 .86 .78 .84 .94
Prkcb1
KLA  ATP  ATP+KLA
 NM_008855 protein kinase C, beta 1 (Prkcb1), mRNA [NM_008855] KLA .92 .95 .93 .78 .77 1.08 1.83
ATP 1.03 1.12 1.09 1.23 .90 2.08 .96
KLA/ATP .98 .99 .82 .89 .62 1.01 1.08
Prkcc
KLA  ATP  ATP+KLA
 NM_011102 protein kinase C, gamma (Prkcc), mRNA [NM_011102] KLA 1.02 1.04 1.11 1.04 .96 1.02 1.05
ATP .98 .98 1.05 1.03 1.08 .96 .95
KLA/ATP 1.21 1.16 1.09 1.07 1.04 .98 .93
Prkx
KLA  ATP  ATP+KLA
 NM_016979 protein kinase, X-linked (Prkx), mRNA [NM_016979] KLA 3.61 3.79 4.67 4.66 4.85 4.19 1.43
ATP .98 .90 .63 .61 1.12 1.90 1.29
KLA/ATP 3.56 3.36 2.62 2.06 2.26 2.87 2.31
Raf1
KLA  ATP  ATP+KLA
 AK036317 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630056E02 product:v-raf-1 leukemia viral oncogene 1, full insert sequence. [AK036317] KLA 1.47 1.34 1.55 1.29 1.59 1.32 1.46
ATP 1.05 .98 .54 .63 3.32 2.07 1.01
KLA/ATP 1.57 1.33 .79 .96 2.26 1.38 1.35
Raf1
KLA  ATP  ATP+KLA
 NM_029780 v-raf-leukemia viral oncogene 1 (Raf1), mRNA [NM_029780] KLA 1.65 1.64 1.93 1.77 1.77 1.72 1.81
ATP .95 .96 .83 .80 2.22 2.92 1.19
KLA/ATP 1.68 1.64 1.39 1.32 1.85 2.50 2.06
Tcf3
KLA  ATP  ATP+KLA
 NM_001079822 transcription factor 3 (Tcf3), transcript variant 1, mRNA [NM_001079822] KLA 1.03 .98 1.01 .98 .98 1.03 1.01
ATP 1.00 1.02 1.00 1.06 1.10 1.07 .99
KLA/ATP 1.07 .99 .97 1.05 1.05 1.11 .96
Tcf7
KLA  ATP  ATP+KLA
 NM_009331 transcription factor 7, T-cell specific (Tcf7), mRNA [NM_009331] KLA 1.00 1.01 1.03 1.00 .98 1.01 1.07
ATP .99 .98 1.02 1.03 1.03 1.00 1.01
KLA/ATP 1.00 1.03 1.04 1.02 1.04 1.02 1.00
Tcf7l2
KLA  ATP  ATP+KLA
 NM_009333 transcription factor 7-like 2, T-cell specific, HMG-box (Tcf7l2), mRNA [NM_009333] KLA 1.01 1.12 1.11 1.31 1.06 1.34 1.29
ATP 1.04 1.05 .94 1.06 .90 .81 .96
KLA/ATP 1.08 1.11 1.05 1.18 1.04 1.02 1.42
Tyr
KLA  ATP  ATP+KLA
 NM_011661 tyrosinase (Tyr), mRNA [NM_011661] KLA .99 1.02 .99 1.01 1.00 1.01 1.03
ATP 1.01 .98 .99 1.03 1.00 1.01 1.00
KLA/ATP 1.01 1.00 1.00 1.01 1.00 1.03 .98
Tyrp1
KLA  ATP  ATP+KLA
 NM_031202 tyrosinase-related protein 1 (Tyrp1), mRNA [NM_031202] KLA .97 .98 1.01 .99 .99 .98 .97
ATP 1.01 .99 1.00 .97 .99 1.00 .98
KLA/ATP .98 .99 1.01 .98 .98 .97 1.00
Wnt1
KLA  ATP  ATP+KLA
 NM_021279 wingless-related MMTV integration site 1 (Wnt1), mRNA [NM_021279] KLA 1.01 1.01 1.05 1.03 1.04 1.04 1.01
ATP .99 .99 1.01 .97 .96 1.01 1.00
KLA/ATP 1.01 1.04 1.06 1.02 1.00 .98 .98
Wnt10a
KLA  ATP  ATP+KLA
 NM_009518 wingless related MMTV integration site 10a (Wnt10a), mRNA [NM_009518] KLA 1.73 1.66 1.33 1.17 1.10 1.02 1.03
ATP 1.03 1.04 .93 1.02 1.04 1.07 1.06
KLA/ATP 1.83 1.67 1.53 1.21 1.10 1.12 1.09
Wnt10b
KLA  ATP  ATP+KLA
 NM_011718 wingless related MMTV integration site 10b (Wnt10b), mRNA [NM_011718] KLA 1.10 .98 1.13 1.01 .96 1.00 .96
ATP 1.02 1.02 .99 1.01 .96 1.02 1.01
KLA/ATP 1.01 1.18 .97 .97 1.03 1.04 .98
Wnt11
KLA  ATP  ATP+KLA
 NM_009519 wingless-related MMTV integration site 11 (Wnt11), mRNA [NM_009519] KLA .97 1.00 .97 1.03 1.16 1.08 1.11
ATP 1.03 1.06 1.08 1.23 1.13 1.03 1.08
KLA/ATP .95 1.00 .95 1.02 .97 1.04 1.04
Wnt16
KLA  ATP  ATP+KLA
 NM_053116 wingless-related MMTV integration site 16 (Wnt16), mRNA [NM_053116] KLA 1.00 1.02 .97 1.02 .96 1.02 1.05
ATP 1.01 1.00 .97 .98 .97 .95 1.02
KLA/ATP .96 1.01 .98 1.03 .99 1.00 .97
Wnt2
KLA  ATP  ATP+KLA
 NM_023653 wingless-related MMTV integration site 2 (Wnt2), mRNA [NM_023653] KLA 1.01 1.00 1.02 .96 1.06 1.03 .94
ATP .97 1.01 1.02 .98 1.00 1.05 1.01
KLA/ATP .97 .94 1.03 1.02 1.00 .99 1.05
Wnt2b
KLA  ATP  ATP+KLA
 NM_009520 wingless related MMTV integration site 2b (Wnt2b), mRNA [NM_009520] KLA 1.04 1.03 .99 1.01 .95 1.02 .99
ATP .95 1.00 .95 .99 .97 1.03 1.01
KLA/ATP 1.02 .99 1.01 1.06 .99 .99 1.02
Wnt3
KLA  ATP  ATP+KLA
 NM_009521 wingless-related MMTV integration site 3 (Wnt3), mRNA [NM_009521] KLA 1.04 1.02 1.04 1.02 1.00 .99 1.00
ATP 1.03 .98 1.04 1.04 .96 1.00 1.02
KLA/ATP 1.03 .99 .98 1.03 1.04 .94 1.03
Wnt3a
KLA  ATP  ATP+KLA
 NM_009522 wingless-related MMTV integration site 3A (Wnt3a), mRNA [NM_009522] KLA 1.01 1.00 1.06 1.02 .99 1.02 .99
ATP .96 .97 1.05 1.04 1.02 1.02 1.04
KLA/ATP 1.02 1.03 .96 1.01 .99 1.06 1.00
Wnt4
KLA  ATP  ATP+KLA
 NM_009523 wingless-related MMTV integration site 4 (Wnt4), mRNA [NM_009523] KLA 1.01 1.01 .97 1.06 1.12 1.02 .93
ATP 1.02 1.06 1.03 1.02 1.00 1.02 .98
KLA/ATP .94 1.01 1.06 1.05 .96 .96 1.00
Wnt5a
KLA  ATP  ATP+KLA
 NM_009524 wingless-related MMTV integration site 5A (Wnt5a), mRNA [NM_009524] KLA .98 1.06 1.01 .96 1.03 1.02 1.07
ATP 1.01 .96 1.06 1.11 1.02 .97 1.03
KLA/ATP 1.05 .96 .96 1.04 1.12 1.06 .96
Wnt5b
KLA  ATP  ATP+KLA
 NM_009525 wingless-related MMTV integration site 5B (Wnt5b), mRNA [NM_009525] KLA 1.04 1.04 1.19 1.11 1.10 1.11 1.05
ATP 1.04 1.01 .95 1.01 .99 1.04 1.05
KLA/ATP 1.05 1.06 1.11 1.07 1.04 1.08 1.05
Wnt6
KLA  ATP  ATP+KLA
 M89800 gb|Mouse Wnt-6 mRNA, complete cds. [M89800] KLA 1.92 1.97 1.93 2.04 2.01 2.62 5.22
ATP .96 .97 1.07 1.03 .76 .94 1.18
KLA/ATP 2.04 1.91 1.96 1.72 1.40 1.31 2.45
Wnt6
KLA  ATP  ATP+KLA
 NM_009526 wingless-related MMTV integration site 6 (Wnt6), mRNA [NM_009526] KLA 2.83 2.51 2.19 2.74 2.92 3.01 5.82
ATP 1.01 .87 1.07 .77 .59 1.11 1.06
KLA/ATP 2.31 2.49 2.69 1.79 1.63 1.26 2.64
Wnt7a
KLA  ATP  ATP+KLA
 NM_009527 wingless-related MMTV integration site 7A (Wnt7a), mRNA [NM_009527] KLA .96 .92 .91 .99 .96 .98 .97
ATP 1.05 .95 .98 .98 1.03 .98 1.11
KLA/ATP .92 .89 .88 .97 1.01 1.04 1.01
Wnt7b
KLA  ATP  ATP+KLA
 NM_009528 wingless-related MMTV integration site 7B (Wnt7b), mRNA [NM_009528] KLA 1.06 1.09 .99 1.09 1.06 1.19 1.26
ATP .99 .98 1.02 1.08 1.02 1.11 1.54
KLA/ATP 1.02 1.01 .99 1.14 1.07 1.09 1.58
Wnt8a
KLA  ATP  ATP+KLA
 NM_009290 wingless-related MMTV integration site 8A (Wnt8a), mRNA [NM_009290] KLA .92 1.01 .99 1.00 1.06 1.01 1.04
ATP 1.00 1.01 1.01 1.04 1.00 1.06 1.05
KLA/ATP 1.07 1.05 .99 1.08 1.07 1.09 1.07
Wnt8b
KLA  ATP  ATP+KLA
 NM_011720 wingless related MMTV integration site 8b (Wnt8b), mRNA [NM_011720] KLA 1.00 1.00 .94 1.03 .98 .98 .97
ATP .99 1.01 1.01 1.01 1.05 1.04 1.03
KLA/ATP .98 1.03 1.00 1.01 .99 1.02 1.02
Wnt9a
KLA  ATP  ATP+KLA
 NM_139298 wingless-type MMTV integration site 9A (Wnt9a), mRNA [NM_139298] KLA .93 .95 .95 1.01 .96 .97 1.01
ATP 1.01 .98 1.01 1.08 1.43 1.02 1.44
KLA/ATP .94 .96 1.03 1.15 1.43 1.15 1.21
Wnt9b
KLA  ATP  ATP+KLA
 NM_011719 wingless-type MMTV integration site 9B (Wnt9b), mRNA [NM_011719] KLA .97 1.00 .94 1.00 .99 .97 1.02
ATP .96 1.02 1.05 .99 .92 1.11 1.08
KLA/ATP .97 .96 .99 .93 .96 1.03 .99