Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Prolactin signaling pathway (mmu04917)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Akt1
KLA  ATP  ATP+KLA
 NM_009652 thymoma viral proto-oncogene 1 (Akt1), mRNA [NM_009652] KLA .80 .80 .75 .75 .71 .70 .82
ATP 1.00 1.02 .76 .85 .76 .68 .84
KLA/ATP .82 .80 .64 .68 .67 .61 .72
Akt2
KLA  ATP  ATP+KLA
 NM_007434 thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, mRNA [NM_007434] KLA 1.45 1.49 1.81 1.61 1.83 1.17 .92
ATP 1.12 1.12 1.00 1.28 1.20 .94 1.06
KLA/ATP 1.48 1.70 1.69 1.58 1.57 1.32 1.27
Akt3
KLA  ATP  ATP+KLA
 NM_011785 thymoma viral proto-oncogene 3 (Akt3), mRNA [NM_011785] KLA 3.42 3.45 5.31 5.16 4.65 3.80 2.12
ATP 1.12 1.22 1.10 1.37 1.02 1.11 1.56
KLA/ATP 3.72 4.17 4.62 4.64 2.74 2.05 3.82
BB229853
KLA  ATP  ATP+KLA
 BB229853 gb|BB229853 RIKEN full-length enriched, 3 days neonate thymus Mus musculus cDNA clone A630023O21 3. [BB229853] KLA 6.32 5.94 6.13 6.41 7.39 12.33 6.08
ATP .39 .24 .33 .38 1.18 5.75 2.85
KLA/ATP 2.27 2.02 3.25 4.04 7.11 10.22 13.93
Ccnd1
KLA  ATP  ATP+KLA
 S78355 gb|Cyl-1=cyclin D1 [mice, BALB/c, brain, mRNA, 3737 nt]. [S78355] KLA .24 .23 .23 .24 .29 .47 .17
ATP 1.02 1.02 .88 .80 .52 .10 .21
KLA/ATP .27 .23 .22 .24 .27 .25 .14
Ccnd2
KLA  ATP  ATP+KLA
 NM_009829 cyclin D2 (Ccnd2), mRNA [NM_009829] KLA 12.92 13.66 11.94 12.37 11.11 5.44 1.53
ATP .98 .75 .50 .57 1.24 2.83 .40
KLA/ATP 11.19 11.62 10.34 7.96 7.92 7.10 2.57
Cga
KLA  ATP  ATP+KLA
 NM_009889 glycoprotein hormones, alpha subunit (Cga), mRNA [NM_009889] KLA .98 .95 .95 1.01 1.01 .95 1.01
ATP .96 .89 .84 .90 1.03 .88 .98
KLA/ATP .99 .98 .83 .89 .98 .91 .86
Cish
KLA  ATP  ATP+KLA
 NM_009895 cytokine inducible SH2-containing protein (Cish), mRNA [NM_009895] KLA 26.44 22.18 9.67 6.27 2.93 2.06 1.53
ATP 1.03 1.35 3.93 7.00 24.56 38.19 5.08
KLA/ATP 26.32 33.26 32.35 24.73 42.75 48.19 11.96
Csn2
KLA  ATP  ATP+KLA
 NM_009972 casein beta (Csn2), mRNA [NM_009972] KLA .99 1.07 1.01 1.02 .97 .99 .99
ATP .99 .94 1.00 1.02 1.01 .96 1.04
KLA/ATP 1.00 .98 1.00 .95 .99 1.01 .99
Cyp17a1
KLA  ATP  ATP+KLA
 NM_007809 cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), mRNA [NM_007809] KLA 1.55 1.60 1.71 1.73 1.51 1.58 1.18
ATP .94 1.01 1.27 1.44 1.39 1.36 1.11
KLA/ATP 1.48 1.79 1.95 2.05 1.92 1.75 1.56
Elf5
KLA  ATP  ATP+KLA
 NM_010125 E74-like factor 5 (Elf5), mRNA [NM_010125] KLA .99 .99 1.04 .98 1.02 1.02 .88
ATP 1.00 1.02 1.05 1.00 1.03 .98 1.00
KLA/ATP .96 1.05 1.03 1.01 1.00 .92 1.01
Esr1
KLA  ATP  ATP+KLA
 NM_007956 estrogen receptor 1 (alpha) (Esr1), mRNA [NM_007956] KLA 1.06 1.05 1.11 1.36 1.33 1.02 .90
ATP 1.05 .92 1.02 .94 1.02 .83 .67
KLA/ATP 1.02 .98 1.09 1.08 1.32 1.07 .71
Esr2
KLA  ATP  ATP+KLA
 NM_207707 estrogen receptor 2 (beta) (Esr2), transcript variant 1, mRNA [NM_207707] KLA 1.00 1.00 1.01 1.00 1.00 1.01 1.02
ATP .99 1.00 1.00 1.00 1.00 1.01 1.01
KLA/ATP 1.00 1.02 .98 .97 1.01 .99 1.00
Fos
KLA  ATP  ATP+KLA
 NM_010234 FBJ osteosarcoma oncogene (Fos), mRNA [NM_010234] KLA .42 .33 .64 .61 .71 .85 .71
ATP 3.48 5.46 23.78 25.22 1.71 2.36 1.50
KLA/ATP .90 1.74 5.97 8.62 1.28 2.42 4.52
Foxo3a
KLA  ATP  ATP+KLA
 AK079567 adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230087I01 product:unclassifiable, full insert sequence. [AK079567] KLA .82 .81 .91 .83 .86 .86 .81
ATP .98 1.00 1.13 1.03 .97 .90 .82
KLA/ATP .86 .80 .90 .99 1.07 .84 .73
Foxo3a
KLA  ATP  ATP+KLA
 NM_019740 forkhead box O3a (Foxo3a), mRNA [NM_019740] KLA .94 .92 .86 .97 .87 1.04 1.04
ATP .99 1.09 1.06 .97 .96 1.07 1.15
KLA/ATP .90 .79 .90 .99 .95 1.04 1.11
Galt
KLA  ATP  ATP+KLA
 NM_016658 galactose-1-phosphate uridyl transferase (Galt), mRNA [NM_016658] KLA .63 .59 .54 .59 .57 .79 1.08
ATP .88 .77 .92 .79 .74 .88 .95
KLA/ATP .53 .53 .60 .49 .59 .80 1.10
Gck
KLA  ATP  ATP+KLA
 NM_010292 glucokinase (Gck), mRNA [NM_010292] KLA 1.03 .99 1.04 1.02 .97 .98 1.00
ATP 1.01 .97 1.08 .99 1.06 .98 .96
KLA/ATP 1.06 1.01 .96 .98 .98 1.01 1.01
Grb2
KLA  ATP  ATP+KLA
 NM_008163 growth factor receptor bound protein 2 (Grb2), mRNA [NM_008163] KLA .92 .88 .90 1.27 1.43 1.22 1.00
ATP 1.02 .83 .51 .42 .92 .70 .57
KLA/ATP .84 .77 .61 .56 1.56 1.49 .52
Grb2
KLA  ATP  ATP+KLA
 U07617 Grb2 adaptor protein (grb2) mRNA, complete cds. [U07617] KLA .83 .80 .95 1.13 1.38 1.36 1.06
ATP .84 .74 .51 .41 .82 .74 .59
KLA/ATP .77 .70 .57 .54 1.49 1.39 .53
Gsk3b
KLA  ATP  ATP+KLA
 NM_019827 glycogen synthase kinase 3 beta (Gsk3b), mRNA [NM_019827] KLA 1.06 1.03 1.11 1.01 1.26 1.28 1.26
ATP 1.18 1.27 1.15 2.07 2.37 2.32 1.67
KLA/ATP 1.15 1.21 .98 1.50 1.67 2.50 2.99
Hras1
KLA  ATP  ATP+KLA
 NM_008284 Harvey rat sarcoma virus oncogene 1 (Hras1), mRNA [NM_008284] KLA .79 .82 .77 .82 .94 1.03 1.07
ATP 1.01 .95 .69 .83 .79 1.12 1.15
KLA/ATP .84 .77 .61 .65 .82 1.00 1.05
Ins1
KLA  ATP  ATP+KLA
 NM_008386 insulin I (Ins1), mRNA [NM_008386] KLA 1.00 .99 .99 1.03 1.01 .98 1.06
ATP .97 1.03 1.00 1.03 .99 1.07 1.05
KLA/ATP 1.03 .93 .98 1.04 1.07 1.03 1.01
Ins2
KLA  ATP  ATP+KLA
 NM_008387 insulin II (Ins2), mRNA [NM_008387] KLA .99 1.00 1.00 1.01 1.00 1.02 1.00
ATP 1.01 .99 1.00 1.00 .98 .99 1.01
KLA/ATP .99 1.01 1.00 .98 .99 .99 .98
Irf1
KLA  ATP  ATP+KLA
 NM_008390 interferon regulatory factor 1 (Irf1), mRNA [NM_008390] KLA 10.08 9.47 8.27 7.31 6.74 6.39 3.17
ATP .95 .81 .80 3.61 2.99 4.15 1.77
KLA/ATP 10.40 10.08 6.59 8.23 12.18 7.53 7.82
Jak2
KLA  ATP  ATP+KLA
 NM_008413 Janus kinase 2 (Jak2), transcript variant 1, mRNA [NM_008413] KLA 14.86 15.05 15.42 14.15 11.46 8.81 5.47
ATP .99 1.06 1.09 1.43 2.83 4.71 1.62
KLA/ATP 13.77 14.74 14.94 12.97 7.53 9.34 9.17
Kras
KLA  ATP  ATP+KLA
 NM_021284 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras), mRNA [NM_021284] KLA .53 .49 .40 .42 .49 .95 1.05
ATP .98 1.01 1.16 1.17 1.39 1.29 1.74
KLA/ATP .50 .47 .50 .56 1.00 1.24 1.58
Lhb
KLA  ATP  ATP+KLA
 AK138425 adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230101A12 product:luteinizing hormone beta, full insert sequence [AK138425] KLA 1.06 1.01 1.02 .98 1.00 1.07 .91
ATP 1.02 1.04 .91 .96 .90 1.05 .95
KLA/ATP .98 .96 1.01 1.03 1.04 1.00 1.09
Lhb
KLA  ATP  ATP+KLA
 NM_008497 luteinizing hormone beta (Lhb), mRNA [NM_008497] KLA 1.16 1.26 1.24 1.20 1.29 1.29 1.23
ATP 1.01 1.01 1.12 1.19 1.22 1.21 1.23
KLA/ATP 1.12 1.12 1.33 1.53 1.47 1.42 1.44
Lhcgr
KLA  ATP  ATP+KLA
 NM_013582 luteinizing hormone/choriogonadotropin receptor (Lhcgr), mRNA [NM_013582] KLA .98 1.06 .99 .95 1.01 1.00 1.04
ATP 1.01 .95 1.00 1.04 1.00 1.03 1.00
KLA/ATP 1.04 1.02 .97 1.01 1.03 1.04 .98
Map2k1
KLA  ATP  ATP+KLA
 NM_008927 mitogen-activated protein kinase kinase 1 (Map2k1), mRNA [NM_008927] KLA 1.82 2.00 2.31 2.03 2.51 2.20 1.51
ATP .99 1.14 .81 .87 .90 1.57 1.11
KLA/ATP 1.90 2.03 1.50 1.93 1.63 2.03 2.06
Map2k2
KLA  ATP  ATP+KLA
 NM_023138 mitogen-activated protein kinase kinase 2 (Map2k2), mRNA [NM_023138] KLA .96 1.01 1.09 .99 1.11 1.15 1.42
ATP 1.07 1.05 .74 .86 1.04 1.16 1.21
KLA/ATP 1.14 1.03 .68 .78 .85 1.01 1.20
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk10
KLA  ATP  ATP+KLA
 AK076990 adult male testis cDNA, RIKEN full-length enriched library, clone:4930597C01 product:mitogen activated protein kinase 10, full insert sequence. [AK076990] KLA 1.03 1.05 .98 1.04 .94 .95 1.02
ATP 1.00 .99 1.06 .97 1.01 .96 .99
KLA/ATP 1.07 1.01 .95 1.05 .82 .95 .87
Mapk10
KLA  ATP  ATP+KLA
 NM_009158 mitogen-activated protein kinase 10 (Mapk10), transcript variant 1, mRNA [NM_009158] KLA .95 1.00 .97 1.01 .99 1.01 .95
ATP 1.01 1.02 .98 1.01 1.04 1.01 .99
KLA/ATP 1.05 .99 1.01 .98 .92 .97 .98
Mapk11
KLA  ATP  ATP+KLA
 NM_011161 mitogen-activated protein kinase 11 (Mapk11), mRNA [NM_011161] KLA 1.28 1.30 1.41 1.46 1.58 1.29 .98
ATP .96 .95 .89 .82 .79 1.09 .85
KLA/ATP 1.44 1.42 1.32 1.23 1.23 .74 .66
Mapk12
KLA  ATP  ATP+KLA
 NM_013871 mitogen-activated protein kinase 12 (Mapk12), mRNA [NM_013871] KLA .94 .86 .87 .81 .77 .68 .49
ATP .97 .83 .92 .90 .86 .90 .51
KLA/ATP .91 .89 .88 .85 1.12 1.14 .53
Mapk13
KLA  ATP  ATP+KLA
 NM_011950 mitogen-activated protein kinase 13 (Mapk13), mRNA [NM_011950] KLA 1.22 1.21 1.35 1.26 1.24 1.13 1.01
ATP 1.08 1.00 1.20 1.20 1.13 1.22 1.39
KLA/ATP 1.22 1.27 1.30 1.30 1.21 1.11 1.47
Mapk14
KLA  ATP  ATP+KLA
 NM_011951 mitogen-activated protein kinase 14 (Mapk14), mRNA [NM_011951] KLA .70 .70 .62 .54 .67 .88 1.11
ATP 1.03 .98 .87 .69 .48 .78 .66
KLA/ATP .74 .68 .52 .46 .38 .45 .62
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mapk8
KLA  ATP  ATP+KLA
 AK162915 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330031O19 product:mitogen activated protein kinase 8, full insert sequence [AK162915] KLA .94 .86 .80 .83 .77 .85 .83
ATP 1.08 1.12 .94 .80 .83 .71 .75
KLA/ATP .83 .81 .80 .74 .74 .75 .67
Mapk8
KLA  ATP  ATP+KLA
 AK163829 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130070A06 product:mitogen activated protein kinase 8, full insert sequence [AK163829] KLA .65 .61 .66 .70 .90 1.02 1.03
ATP .99 .94 1.68 1.44 1.75 1.84 1.10
KLA/ATP .63 .67 1.11 1.00 2.01 1.68 1.15
Mapk8
KLA  ATP  ATP+KLA
 NM_016700 mitogen-activated protein kinase 8 (Mapk8), mRNA [NM_016700] KLA .96 1.00 .94 .96 .94 .99 1.04
ATP 1.01 1.05 1.01 .99 1.03 .98 1.02
KLA/ATP .96 .97 .96 .97 .93 .94 .96
Mapk9
KLA  ATP  ATP+KLA
 NM_016961 mitogen-activated protein kinase 9 (Mapk9), transcript variant 2, mRNA [NM_016961] KLA 1.28 1.37 1.59 1.60 1.61 1.43 1.38
ATP 1.03 .99 .74 .71 .79 1.20 1.01
KLA/ATP 1.53 1.30 1.07 .99 .83 1.10 1.40
Mapk9
KLA  ATP  ATP+KLA
 NM_207692 mitogen-activated protein kinase 9 (Mapk9), transcript variant 1, mRNA [NM_207692] KLA 1.39 1.53 1.69 1.69 1.55 1.44 1.51
ATP .95 .92 .75 .85 .70 1.46 1.17
KLA/ATP 1.37 1.35 .99 1.18 .91 1.22 1.62
Mm.12688
5
KLA  ATP  ATP+KLA
 34328248 Unknown KLA .34 .32 .25 .32 .32 .39 .63
ATP 1.05 1.19 1.42 1.13 .60 .53 .59
KLA/ATP .30 .27 .37 .35 .38 .32 .38
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.27304
9
KLA  ATP  ATP+KLA
 119672895 Unknown KLA .23 .22 .22 .22 .30 .51 .16
ATP 1.08 1.05 .88 .78 .47 .09 .20
KLA/ATP .28 .22 .21 .24 .26 .22 .12
Mm.27970
KLA  ATP  ATP+KLA
 13994135 Unknown KLA 1.06 1.11 1.16 1.07 1.11 1.08 .95
ATP 1.02 1.09 1.05 1.05 .94 1.16 1.32
KLA/ATP 1.10 1.19 1.11 1.04 1.08 1.02 1.33
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nras
KLA  ATP  ATP+KLA
 NM_010937 neuroblastoma ras oncogene (Nras), mRNA [NM_010937] KLA 1.20 1.22 1.27 1.20 1.09 .91 .84
ATP .98 .91 .69 .61 .59 .67 .78
KLA/ATP 1.22 1.14 .97 .79 .73 .61 .72
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Prl
KLA  ATP  ATP+KLA
 NM_011164 prolactin (Prl), mRNA [NM_011164] KLA 1.01 1.00 1.06 1.02 1.05 .96 .97
ATP .99 1.02 .97 .98 .97 .95 1.00
KLA/ATP 1.00 1.01 1.00 .97 .96 .87 .95
Prlr
KLA  ATP  ATP+KLA
 AK083198 adult male hippocampus cDNA, RIKEN full-length enriched library, clone:C630026G18 product:unclassifiable, full insert sequence [AK083198] KLA .99 1.07 1.00 .95 1.01 .90 1.01
ATP 1.02 .94 .97 1.00 .97 .94 .96
KLA/ATP .98 .94 .96 .96 .99 1.07 1.02
Prlr
KLA  ATP  ATP+KLA
 AK087727 2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330012C04 product:hypothetical protein, full insert sequence [AK087727] KLA 1.03 1.00 .99 1.01 1.02 1.04 .99
ATP 1.00 .95 1.13 1.06 .97 .98 1.04
KLA/ATP .97 1.01 .88 1.02 1.01 1.03 1.05
Prlr
KLA  ATP  ATP+KLA
 NM_011169 prolactin receptor (Prlr), mRNA [NM_011169] KLA .93 1.03 1.12 1.06 1.05 1.14 1.15
ATP .95 .99 1.11 1.13 1.06 1.19 1.18
KLA/ATP 1.02 1.01 1.05 1.10 1.10 1.21 1.07
Raf1
KLA  ATP  ATP+KLA
 AK036317 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630056E02 product:v-raf-1 leukemia viral oncogene 1, full insert sequence. [AK036317] KLA 1.47 1.34 1.55 1.29 1.59 1.32 1.46
ATP 1.05 .98 .54 .63 3.32 2.07 1.01
KLA/ATP 1.57 1.33 .79 .96 2.26 1.38 1.35
Raf1
KLA  ATP  ATP+KLA
 NM_029780 v-raf-leukemia viral oncogene 1 (Raf1), mRNA [NM_029780] KLA 1.65 1.64 1.93 1.77 1.77 1.72 1.81
ATP .95 .96 .83 .80 2.22 2.92 1.19
KLA/ATP 1.68 1.64 1.39 1.32 1.85 2.50 2.06
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Shc1
KLA  ATP  ATP+KLA
 NM_011368 src homology 2 domain-containing transforming protein C1 (Shc1), transcript variant 2, mRNA [NM_011368] KLA .88 .87 .86 .83 1.09 1.11 1.12
ATP 1.04 1.25 .85 1.17 .93 1.16 1.00
KLA/ATP .93 .96 .62 .96 .75 1.25 1.19
Shc2
KLA  ATP  ATP+KLA
 NM_001024539 src homology 2 domain-containing transforming protein C2 (Shc2), mRNA [NM_001024539] KLA 1.19 1.25 1.22 1.16 1.15 1.14 .98
ATP 1.04 1.14 1.15 1.53 1.29 1.06 1.09
KLA/ATP 1.26 1.24 1.26 1.49 1.31 1.30 1.30
Shc3
KLA  ATP  ATP+KLA
 NM_009167 src homology 2 domain-containing transforming protein C3 (Shc3), mRNA [NM_009167] KLA 1.00 .98 1.06 1.06 1.12 1.08 1.04
ATP .99 1.02 1.00 1.05 1.00 1.08 1.08
KLA/ATP 1.08 1.06 1.01 1.06 1.03 1.12 1.41
Shc4
KLA  ATP  ATP+KLA
 NM_199022 SHC (Src homology 2 domain containing) family, member 4 (Shc4), mRNA [NM_199022] KLA 1.03 1.03 1.01 1.06 1.09 1.03 1.06
ATP .99 1.00 1.03 1.02 1.04 1.04 1.01
KLA/ATP .98 .97 1.06 1.05 1.00 1.00 1.14
Slc2a2
KLA  ATP  ATP+KLA
 NM_031197 solute carrier family 2 (facilitated glucose transporter), member 2 (Slc2a2), mRNA [NM_031197] KLA 1.01 1.03 .97 1.00 1.01 1.02 1.04
ATP 1.02 .97 1.07 1.00 1.00 1.03 1.00
KLA/ATP 1.01 1.01 .95 1.00 1.05 1.02 1.01
Socs1
KLA  ATP  ATP+KLA
 NM_009896 suppressor of cytokine signaling 1 (Socs1), mRNA [NM_009896] KLA 27.36 22.16 20.64 23.08 17.74 21.71 10.12
ATP .91 .72 2.03 12.69 9.16 19.87 6.80
KLA/ATP 26.70 24.56 28.15 31.28 26.32 29.95 22.51
Socs2
KLA  ATP  ATP+KLA
 AK033206 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030460M17 product:hypothetical SH2 motif [AK033206] KLA 1.08 1.11 1.22 1.13 1.11 1.08 .97
ATP .98 .97 1.03 1.03 1.29 1.30 1.29
KLA/ATP 1.06 1.09 1.07 1.33 2.01 1.85 1.98
Socs2
KLA  ATP  ATP+KLA
 NM_007706 suppressor of cytokine signaling 2 (Socs2), mRNA [NM_007706] KLA 2.03 2.28 2.61 1.98 1.59 1.72 1.28
ATP 1.04 1.04 1.05 1.17 2.11 3.47 3.02
KLA/ATP 2.18 1.92 1.71 2.33 3.37 5.81 4.64
Socs3
KLA  ATP  ATP+KLA
 NM_007707 suppressor of cytokine signaling 3 (Socs3), mRNA [NM_007707] KLA 7.56 6.68 6.29 7.36 6.47 7.03 5.33
ATP 1.51 1.75 4.63 6.27 6.92 7.74 4.64
KLA/ATP 6.82 6.77 9.19 8.32 9.51 8.98 8.33
Socs4
KLA  ATP  ATP+KLA
 AK080408 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730004F22 product:unclassifiable, full insert sequence [AK080408] KLA .89 .90 .87 .74 .87 1.05 .98
ATP 1.01 .97 1.11 .76 1.00 .82 1.11
KLA/ATP .80 .82 .82 .70 1.00 .80 .76
Socs4
KLA  ATP  ATP+KLA
 NM_080843 suppressor of cytokine signaling 4 (Socs4), mRNA [NM_080843] KLA 1.31 1.29 1.45 1.31 1.42 1.90 2.37
ATP 1.02 1.16 1.31 1.39 1.86 2.43 2.69
KLA/ATP 1.33 1.24 1.26 1.31 1.39 2.94 3.73
Socs5
KLA  ATP  ATP+KLA
 NM_019654 suppressor of cytokine signaling 5 (Socs5), mRNA [NM_019654] KLA .37 .34 .33 .32 .29 .43 .66
ATP 1.13 1.24 1.29 1.17 .67 .52 .60
KLA/ATP .44 .37 .41 .39 .41 .37 .37
Socs6
KLA  ATP  ATP+KLA
 AK142069 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230020G23 product:suppressor of cytokine signaling 6, full insert sequence [AK142069] KLA .89 .96 .95 .91 .82 .89 .83
ATP 1.11 1.04 .91 .88 1.06 .84 1.24
KLA/ATP 1.08 .94 .71 .80 .76 .75 .74
Socs6
KLA  ATP  ATP+KLA
 NM_018821 suppressor of cytokine signaling 6 (Socs6), mRNA [NM_018821] KLA 1.00 .99 1.16 .98 .87 .81 .61
ATP 1.02 1.10 1.38 1.47 2.29 1.81 1.65
KLA/ATP .95 .96 1.00 .83 1.09 1.42 1.03
Socs7
KLA  ATP  ATP+KLA
 NM_138657 suppressor of cytokine signaling 7 (Socs7), mRNA [NM_138657] KLA 1.86 1.79 2.05 1.76 1.69 1.24 .99
ATP 1.07 1.08 1.11 1.14 1.29 1.82 1.71
KLA/ATP 1.96 1.99 1.66 1.80 1.49 2.04 2.09
Sos1
KLA  ATP  ATP+KLA
 NM_009231 Son of sevenless homolog 1 (Drosophila) (Sos1), mRNA [NM_009231] KLA 2.36 2.40 3.42 3.15 2.78 1.81 1.71
ATP .99 1.00 .99 1.15 1.14 1.25 1.24
KLA/ATP 2.41 2.26 1.95 2.44 1.47 1.66 1.37
Sos2
KLA  ATP  ATP+KLA
 XM_127051 gb|PREDICTED: Mus musculus Son of sevenless homolog 2 (Drosophila) (Sos2), mRNA [XM_127051] KLA .81 .77 .79 .92 1.04 1.06 1.20
ATP 1.00 1.00 1.09 .79 .68 .81 .94
KLA/ATP .77 .69 .71 .60 .64 .77 1.07
Src
KLA  ATP  ATP+KLA
 NM_009271 Rous sarcoma oncogene (Src), transcript variant 1, mRNA [NM_009271] KLA 6.99 7.23 7.54 5.99 5.34 3.39 3.00
ATP 1.02 1.06 1.06 2.08 4.41 5.03 3.97
KLA/ATP 7.44 7.51 5.48 6.24 4.86 5.86 7.90
Stat1
KLA  ATP  ATP+KLA
 NM_009283 signal transducer and activator of transcription 1 (Stat1), mRNA [NM_009283] KLA 2.90 2.72 3.00 3.64 4.58 6.51 5.58
ATP 1.01 .92 .89 .72 .51 2.22 3.07
KLA/ATP 2.73 2.65 2.34 1.95 1.99 4.70 8.66
Stat3
KLA  ATP  ATP+KLA
 NM_213659 signal transducer and activator of transcription 3 (Stat3), transcript variant 1, mRNA [NM_213659] KLA 4.36 4.42 4.67 6.02 4.95 3.45 1.46
ATP 1.01 .97 1.07 1.17 2.47 4.04 1.47
KLA/ATP 4.02 4.57 6.65 6.51 7.06 7.39 3.61
Stat5a
KLA  ATP  ATP+KLA
 NM_011488 signal transducer and activator of transcription 5A (Stat5a), mRNA [NM_011488] KLA 8.23 8.24 6.89 4.88 4.35 1.98 1.01
ATP 1.07 1.14 1.07 1.26 3.23 3.14 1.52
KLA/ATP 8.70 9.53 7.33 6.68 4.32 2.73 1.72
Stat5b
KLA  ATP  ATP+KLA
 AK137889 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130035C01 product:unclassifiable, full insert sequence. [AK137889] KLA 1.10 1.01 .98 .90 1.03 .93 .88
ATP .90 .87 .61 .69 1.01 .97 .89
KLA/ATP 1.12 1.00 .87 .85 .95 1.07 .83
Stat5b
KLA  ATP  ATP+KLA
 NM_011489 signal transducer and activator of transcription 5B (Stat5b), transcript variant 1, mRNA [NM_011489] KLA 2.91 2.81 3.42 2.69 2.23 1.95 1.32
ATP .99 1.04 1.16 .97 1.00 1.84 2.09
KLA/ATP 2.96 3.05 3.17 2.99 1.86 1.87 3.40
Th
KLA  ATP  ATP+KLA
 NM_009377 tyrosine hydroxylase (Th), mRNA [NM_009377] KLA 1.00 1.01 1.00 1.00 1.00 1.00 1.00
ATP .98 1.01 1.00 1.00 1.00 .99 1.01
KLA/ATP 1.00 1.01 1.01 1.00 1.01 .98 1.02
Tnfrsf11
a
KLA  ATP  ATP+KLA
 NM_009399 tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a), mRNA [NM_009399] KLA 1.43 1.33 1.36 1.58 1.87 1.83 1.47
ATP 1.07 1.17 1.02 1.19 .95 .82 1.13
KLA/ATP 1.55 1.46 1.16 1.46 .79 .95 1.92
Tnfsf11
KLA  ATP  ATP+KLA
 NM_011613 tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11), mRNA [NM_011613] KLA 1.00 1.00 1.08 .96 .97 1.01 .96
ATP 1.01 1.05 .97 .86 1.05 1.03 1.01
KLA/ATP 1.04 1.05 .99 1.04 1.01 1.02 .99
Wap
KLA  ATP  ATP+KLA
 NM_011709 whey acidic protein (Wap), mRNA [NM_011709] KLA 1.02 .97 1.02 1.01 1.02 .99 1.02
ATP .98 .98 .94 1.02 .95 1.01 1.01
KLA/ATP .98 .98 .96 .95 1.02 .97 1.03