Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

Search by fold change ratio | Search by KEGG pathway | Search by LIPID MAPS lipid pathway

Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Mineral absorption (mmu04978)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
AK078587
KLA  ATP  ATP+KLA
 AK078587 11 days embryo gonad cDNA, RIKEN full-length enriched library, clone:7030411M21 product:unclassifiable, full insert sequence [AK078587] KLA 1.37 1.28 1.13 1.06 1.15 1.31 1.22
ATP 1.04 1.08 1.21 1.22 1.27 1.12 1.14
KLA/ATP 1.48 1.66 1.97 1.26 1.17 1.03 1.28
Atox1
KLA  ATP  ATP+KLA
 NM_009720 ATX1 (antioxidant protein 1) homolog 1 (yeast) (Atox1), mRNA [NM_009720] KLA .85 .83 .92 .83 .78 .83 1.15
ATP 1.02 1.12 1.07 1.45 1.27 1.21 1.54
KLA/ATP .99 1.01 .93 1.23 1.11 1.14 1.73
Atp1a1
KLA  ATP  ATP+KLA
 NM_144900 ATPase, Na+/K+ transporting, alpha 1 polypeptide (Atp1a1), mRNA [NM_144900] KLA .78 .94 .68 .81 .62 .55 .75
ATP 1.02 1.05 .86 .85 1.77 2.54 1.11
KLA/ATP .83 .99 .80 .75 .91 1.15 .68
Atp1a2
KLA  ATP  ATP+KLA
 NM_178405 ATPase, Na+/K+ transporting, alpha 2 polypeptide (Atp1a2), mRNA [NM_178405] KLA 1.03 .98 1.03 1.05 1.03 .98 1.02
ATP 1.03 .98 1.06 1.05 1.05 .93 1.07
KLA/ATP 1.04 1.05 1.02 1.02 .98 .92 1.02
Atp1a3
KLA  ATP  ATP+KLA
 AK053751 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130306P09 product:ATPase, Na+/K+ transporting, alpha 3 polypeptide, full insert sequence. [AK053751] KLA .88 .87 .74 .80 .84 .88 .93
ATP .96 .83 .80 .88 .94 .89 1.15
KLA/ATP .89 .86 .79 .90 .93 .84 .92
Atp1a3
KLA  ATP  ATP+KLA
 NM_144921 ATPase, Na+/K+ transporting, alpha 3 polypeptide (Atp1a3), mRNA [NM_144921] KLA .99 .87 .96 .86 .81 .61 .52
ATP 1.22 1.21 1.16 1.38 1.27 .92 1.30
KLA/ATP .96 1.10 1.17 1.42 1.11 .91 .93
Atp1b1
KLA  ATP  ATP+KLA
 NM_009721 ATPase, Na+/K+ transporting, beta 1 polypeptide (Atp1b1), mRNA [NM_009721] KLA .97 1.02 1.08 .98 .95 1.01 1.09
ATP 1.07 1.05 1.09 1.09 1.02 1.17 1.11
KLA/ATP .99 .99 .93 1.02 1.00 1.07 1.04
Atp1b2
KLA  ATP  ATP+KLA
 NM_013415 ATPase, Na+/K+ transporting, beta 2 polypeptide (Atp1b2), mRNA [NM_013415] KLA 1.18 1.09 1.11 1.12 1.16 1.12 1.15
ATP .95 .98 .99 1.26 1.06 1.10 1.07
KLA/ATP 1.15 1.16 1.09 1.19 1.27 1.13 1.02
Atp1b3
KLA  ATP  ATP+KLA
 NM_007502 ATPase, Na+/K+ transporting, beta 3 polypeptide (Atp1b3), mRNA [NM_007502] KLA 1.86 2.10 2.25 2.21 2.68 3.26 3.45
ATP 1.08 1.09 .93 1.13 1.55 2.14 2.38
KLA/ATP 1.95 2.10 1.84 2.34 2.20 2.96 4.69
Atp1b4
KLA  ATP  ATP+KLA
 NM_133690 ATPase, (Na+)/K+ transporting, beta 4 polypeptide (Atp1b4), mRNA [NM_133690] KLA .99 1.02 1.03 1.01 .95 .90 1.00
ATP 1.00 1.05 1.04 .98 1.07 .98 .97
KLA/ATP 1.00 1.05 1.03 1.04 .96 .97 1.01
Atp2b1
KLA  ATP  ATP+KLA
 AK053569 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130111D10 product:unclassifiable, full insert sequence. [AK053569] KLA 1.18 1.02 .86 .87 .88 .99 .97
ATP 1.38 1.60 8.03 2.45 1.66 1.16 .94
KLA/ATP 1.32 1.41 6.67 1.98 1.15 1.08 .96
Atp2b1
KLA  ATP  ATP+KLA
 AK161995 12 days embryo male wolffian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6720440F18 product:Plasma membrane calcium pump isoform 1b (Fragment) homolog [Canis familiaris], full insert sequence. [AK16199 KLA 1.64 1.50 1.23 1.02 .71 .75 .92
ATP 1.04 1.12 1.69 1.64 1.34 1.03 .66
KLA/ATP 1.69 1.58 2.20 1.99 1.03 .67 .57
Atp2b1
KLA  ATP  ATP+KLA
 NM_026482 ATPase, Ca++ transporting, plasma membrane 1 (Atp2b1), mRNA [NM_026482] KLA 1.91 1.76 1.64 1.21 .84 .79 1.07
ATP 1.00 1.01 1.43 2.32 2.28 1.71 1.06
KLA/ATP 1.86 1.85 2.23 2.48 1.71 1.05 1.04
Atp7a
KLA  ATP  ATP+KLA
 AK033254 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030476D18 product:unclassifiable, full insert sequence. [AK033254] KLA .91 .84 .84 .89 1.31 1.15 1.12
ATP 1.80 1.90 1.18 .84 1.39 1.31 1.27
KLA/ATP 1.35 1.64 1.55 .94 1.17 1.25 1.59
Atp7a
KLA  ATP  ATP+KLA
 NM_009726 ATPase, Cu++ transporting, alpha polypeptide (Atp7a), transcript variant 2, mRNA [NM_009726] KLA .61 .61 .57 .69 .95 1.33 1.30
ATP 1.02 1.04 1.30 1.20 1.01 1.57 1.14
KLA/ATP .65 .64 .81 .78 .85 1.38 1.78
Clcn2
KLA  ATP  ATP+KLA
 AF097415 chloride channel CLC-2 (Clcn2) mRNA, complete cds. [AF097415] KLA 1.06 1.08 1.00 .89 .95 .93 1.03
ATP 1.00 1.03 1.19 1.02 .88 1.03 .96
KLA/ATP 1.05 1.07 1.23 .96 .91 .93 1.00
Clcn2
KLA  ATP  ATP+KLA
 NM_009900 chloride channel 2 (Clcn2), mRNA [NM_009900] KLA 1.02 .96 .95 .89 .92 .94 1.07
ATP 1.02 1.02 1.08 1.03 .95 1.03 1.01
KLA/ATP 1.09 .99 .99 .93 .98 .95 .99
Cybrd1
KLA  ATP  ATP+KLA
 NM_028593 cytochrome b reductase 1 (Cybrd1), mRNA [NM_028593] KLA 1.03 1.01 .96 .98 1.03 .99 .95
ATP 1.00 1.03 .98 .96 .98 1.04 .99
KLA/ATP .96 .95 .98 .96 1.04 .99 .99
Fth1
KLA  ATP  ATP+KLA
 NM_010239 ferritin heavy chain 1 (Fth1), mRNA [NM_010239] KLA .89 .88 .91 1.07 1.36 2.06 4.05
ATP .94 .88 .94 .85 1.27 2.56 3.84
KLA/ATP .80 .82 .97 .96 1.34 2.15 3.53
Ftl1
KLA  ATP  ATP+KLA
 NM_010240 ferritin light chain 1 (Ftl1), mRNA [NM_010240] KLA .63 .64 .56 .49 .54 .57 1.21
ATP 1.02 1.11 .77 1.09 1.00 1.01 1.89
KLA/ATP .65 .62 .41 .60 .60 .77 1.88
Ftmt
KLA  ATP  ATP+KLA
 NM_026286 ferritin mitochondrial (Ftmt), nuclear gene encoding mitochondrial protein, mRNA [NM_026286] KLA 1.03 1.07 1.10 1.07 1.10 1.04 1.04
ATP 1.07 1.02 1.03 1.04 1.00 .99 1.02
KLA/ATP 1.07 1.09 1.14 1.04 1.04 1.08 1.05
Fxyd2
KLA  ATP  ATP+KLA
 NM_052823 FXYD domain-containing ion transport regulator 2 (Fxyd2), transcript variant b, mRNA [NM_052823] KLA 1.07 .97 1.09 .98 1.02 .96 .83
ATP 1.07 1.22 1.00 1.14 1.00 1.22 4.11
KLA/ATP 1.06 1.11 .96 1.13 .98 1.01 1.02
Heph
KLA  ATP  ATP+KLA
 NM_010417 hephaestin (Heph), transcript variant 1, mRNA [NM_010417] KLA .98 .97 .93 1.01 .94 1.00 1.03
ATP 1.00 1.02 .99 .95 .94 1.01 1.13
KLA/ATP .97 .99 .99 .90 .96 1.00 .99
Heph
KLA  ATP  ATP+KLA
 NM_181273 hephaestin (Heph), transcript variant 2, mRNA [NM_181273] KLA 1.11 .99 .97 .99 .97 .94 .93
ATP 1.00 .95 .93 .99 .96 .99 .99
KLA/ATP .97 .99 1.01 .98 1.00 .90 .97
Hmox1
KLA  ATP  ATP+KLA
 NM_010442 heme oxygenase (decycling) 1 (Hmox1), mRNA [NM_010442] KLA .30 .31 .32 .45 1.00 2.36 3.22
ATP .91 .98 .96 1.24 2.53 5.47 2.27
KLA/ATP .31 .30 .40 .87 2.26 4.40 3.94
Hmox2
KLA  ATP  ATP+KLA
 NM_010443 heme oxygenase (decycling) 2 (Hmox2), mRNA [NM_010443] KLA .75 .83 .93 1.06 1.45 1.79 1.39
ATP 1.14 1.17 .88 .88 .55 .72 1.76
KLA/ATP .90 .84 .71 .93 1.00 1.22 2.44
Mm.24508
4
KLA  ATP  ATP+KLA
 144227202 Unknown KLA 1.06 1.07 1.19 1.42 1.09 .83 .67
ATP .99 1.02 1.16 1.40 1.51 1.67 1.61
KLA/ATP 1.04 1.06 1.35 1.56 1.65 1.92 2.49
Mm.25237
KLA  ATP  ATP+KLA
 141802859 Unknown KLA 1.03 1.07 1.05 1.08 1.02 1.02 1.00
ATP .98 1.02 .89 .99 .99 1.03 1.09
KLA/ATP .92 .94 1.11 1.03 1.02 .97 1.09
Mt1
KLA  ATP  ATP+KLA
 NM_013602 metallothionein 1 (Mt1), mRNA [NM_013602] KLA 1.50 1.50 1.41 1.12 .91 .46 .33
ATP 1.06 1.19 1.27 1.89 2.04 2.56 .70
KLA/ATP 1.84 1.91 1.78 2.74 2.56 1.96 .38
Mt2
KLA  ATP  ATP+KLA
 NM_008630 metallothionein 2 (Mt2), mRNA [NM_008630] KLA 8.77 7.53 6.36 6.87 4.27 1.52 .25
ATP .87 .86 1.15 1.42 3.74 11.38 .82
KLA/ATP 8.06 8.80 9.96 10.06 8.80 6.34 .74
S100g
KLA  ATP  ATP+KLA
 NM_009789 S100 calcium binding protein G (S100g), mRNA [NM_009789] KLA 1.04 1.07 1.01 1.03 1.08 1.00 1.00
ATP .98 1.05 1.01 .97 .99 1.03 1.03
KLA/ATP 1.00 1.04 .99 1.06 .98 .96 1.03
Slc11a1
KLA  ATP  ATP+KLA
 NM_013612 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (Slc11a1), mRNA [NM_013612] KLA .69 .70 .70 .66 .98 1.43 2.68
ATP .99 1.07 .84 .93 .97 1.65 3.01
KLA/ATP .75 .72 .54 .62 .61 1.42 4.71
Slc11a2
KLA  ATP  ATP+KLA
 AK148276 B16 F10Y cells cDNA, RIKEN full-length enriched library, clone:G370074D17 product:solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2, full insert sequence [AK148276] KLA 4.68 4.47 5.11 5.84 7.80 4.69 3.36
ATP 1.10 1.31 1.75 2.78 4.90 3.41 2.70
KLA/ATP 4.73 4.82 5.48 5.26 3.72 3.15 3.67
Slc11a2
KLA  ATP  ATP+KLA
 NM_008732 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2), mRNA [NM_008732] KLA 2.46 2.36 2.40 2.57 2.87 2.63 1.86
ATP 1.00 1.01 1.05 1.54 2.27 1.88 1.08
KLA/ATP 2.41 2.15 2.32 2.50 2.87 2.33 1.61
Slc26a3
KLA  ATP  ATP+KLA
 AK035716 adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530095G06 product:solute carrier family 26, member 3, full insert sequence. [AK035716] KLA .99 1.00 .99 1.02 .92 1.01 .99
ATP 1.04 1.05 .96 .99 .97 .98 1.28
KLA/ATP .97 1.07 .96 .99 .94 1.04 1.05
Slc26a3
KLA  ATP  ATP+KLA
 NM_021353 solute carrier family 26, member 3 (Slc26a3), mRNA [NM_021353] KLA 1.01 .98 1.00 1.02 .96 1.00 .96
ATP .99 .98 .96 .99 .99 1.01 .96
KLA/ATP 1.04 .99 1.04 .96 .98 .97 1.02
Slc26a6
KLA  ATP  ATP+KLA
 NM_134420 solute carrier family 26, member 6 (Slc26a6), mRNA [NM_134420] KLA .74 .72 .78 .75 .74 .71 .95
ATP .98 .88 .80 .75 .96 1.10 1.28
KLA/ATP .79 .78 .66 .64 .69 .78 1.06
Slc26a9
KLA  ATP  ATP+KLA
 NM_177243 solute carrier family 26, member 9 (Slc26a9), mRNA [NM_177243] KLA 1.02 1.07 1.11 1.11 1.19 1.08 1.04
ATP .97 1.02 1.11 1.17 1.21 1.04 1.38
KLA/ATP 1.09 1.04 1.13 1.07 1.14 1.14 1.98
Slc30a1
KLA  ATP  ATP+KLA
 NM_009579 solute carrier family 30 (zinc transporter), member 1 (Slc30a1), mRNA [NM_009579] KLA 2.36 2.66 2.68 2.27 2.06 2.83 1.34
ATP 1.03 1.00 .85 .71 1.96 4.54 2.24
KLA/ATP 2.38 2.48 2.18 3.64 12.19 10.74 3.35
Slc31a1
KLA  ATP  ATP+KLA
 NM_175090 solute carrier family 31, member 1 (Slc31a1), mRNA [NM_175090] KLA 1.96 2.07 2.30 2.36 3.09 4.15 3.13
ATP 1.14 1.16 1.14 1.25 2.49 3.13 1.94
KLA/ATP 2.10 2.18 2.24 2.49 2.96 3.08 4.07
Slc34a2
KLA  ATP  ATP+KLA
 NM_011402 solute carrier family 34 (sodium phosphate), member 2 (Slc34a2), mRNA [NM_011402] KLA .99 1.02 .99 1.03 1.00 1.04 1.07
ATP .98 1.03 1.01 1.06 1.02 1.03 1.00
KLA/ATP 1.05 1.01 1.05 1.04 1.06 1.04 .96
Slc39a4
KLA  ATP  ATP+KLA
 NM_028064 solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA [NM_028064] KLA 1.30 1.21 1.18 1.26 1.34 1.60 2.45
ATP .85 .71 .89 .82 1.47 5.69 4.50
KLA/ATP 1.03 1.05 1.20 .98 1.72 4.22 5.60
Slc40a1
KLA  ATP  ATP+KLA
 NM_016917 solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), mRNA [NM_016917] KLA .10 .10 .08 .07 .07 .08 .10
ATP 1.02 .97 .99 .48 .53 2.17 .99
KLA/ATP .12 .09 .13 .11 .25 1.40 1.12
Slc46a1
KLA  ATP  ATP+KLA
 NM_026740 solute carrier family 46, member 1 (Slc46a1), mRNA [NM_026740] KLA .69 .70 .68 .63 .51 .55 .94
ATP .94 .99 1.24 1.13 .79 .49 2.42
KLA/ATP .68 .68 .78 .73 .60 .49 1.32
Slc5a1
KLA  ATP  ATP+KLA
 NM_019810 solute carrier family 5 (sodium/glucose cotransporter), member 1 (Slc5a1), mRNA [NM_019810] KLA 1.02 1.02 1.03 1.04 .99 .93 1.06
ATP 1.03 1.03 1.02 1.05 1.04 .98 .97
KLA/ATP 1.02 .94 1.02 1.03 1.03 1.04 1.02
Slc6a19
KLA  ATP  ATP+KLA
 NM_028878 solute carrier family 6 (neurotransmitter transporter), member 19 (Slc6a19), mRNA [NM_028878] KLA 1.22 1.21 1.43 1.38 1.20 1.18 1.42
ATP 1.04 .97 .99 1.05 1.41 1.62 2.29
KLA/ATP 1.29 1.25 1.17 1.11 1.35 3.70 7.99
Slc8a1
KLA  ATP  ATP+KLA
 AF004666 sodium-calcium exchanger (NCX1) mRNA, complete cds. [AF004666] KLA 1.13 1.10 1.22 1.44 1.52 1.55 1.10
ATP 1.03 1.05 1.22 1.12 .65 .49 .67
KLA/ATP 1.04 1.21 1.30 1.44 .81 .63 1.01
Slc8a1
KLA  ATP  ATP+KLA
 AF108396 sodium/calcium exchanger isoform NaCa3 (Ncx1) mRNA, partial cds. [AF108396] KLA 1.07 1.18 1.30 1.22 1.31 1.39 1.21
ATP 1.03 1.02 1.10 1.07 .88 .91 1.23
KLA/ATP 1.15 1.17 1.14 1.22 .96 1.01 1.77
Slc8a1
KLA  ATP  ATP+KLA
 NM_011406 solute carrier family 8 (sodium/calcium exchanger), member 1 (Slc8a1), transcript variant A, mRNA [NM_011406] KLA 1.12 1.16 1.22 1.25 1.35 1.33 1.11
ATP 1.03 1.04 1.07 1.10 .93 .90 1.19
KLA/ATP 1.13 1.24 1.19 1.16 .93 1.06 1.62
Slc9a3
KLA  ATP  ATP+KLA
 AK033564 adult male colon cDNA, RIKEN full-length enriched library, clone:9030624O13 product:SODIUM [AK033564] KLA .96 .94 .91 .97 .95 1.03 .99
ATP 1.06 1.02 1.01 .95 .90 .95 1.08
KLA/ATP .97 .91 .93 .95 1.02 1.03 1.01
Steap1
KLA  ATP  ATP+KLA
 NM_027399 six transmembrane epithelial antigen of the prostate 1 (Steap1), mRNA [NM_027399] KLA 1.05 .98 1.04 .95 .97 .99 .94
ATP 1.01 .97 1.04 1.09 .99 1.08 1.06
KLA/ATP .99 1.06 1.02 1.04 .96 .98 1.04
Steap2
KLA  ATP  ATP+KLA
 NM_001103157 six transmembrane epithelial antigen of prostate 2 (Steap2), transcript variant 1, mRNA [NM_001103157] KLA .98 .97 1.08 .98 1.03 1.05 1.03
ATP 1.01 1.04 1.04 1.02 1.00 .99 1.05
KLA/ATP 1.03 1.02 1.02 1.03 1.02 1.06 .98
Trf
KLA  ATP  ATP+KLA
 NM_133977 transferrin (Trf), mRNA [NM_133977] KLA .84 .95 .94 .84 .74 .54 .20
ATP 1.02 1.05 .97 1.23 1.04 1.04 .63
KLA/ATP .94 .93 .88 1.07 .71 .77 .40
Trpm6
KLA  ATP  ATP+KLA
 AK080899 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430202L17 product:similar to CHANNEL-KINASE 2 [Homo sapiens], full insert sequence. [AK080899] KLA 1.00 1.02 .95 1.02 .99 1.02 1.02
ATP .97 1.06 .87 .94 .96 1.09 1.03
KLA/ATP .98 .98 .98 1.00 .98 1.01 1.06
Trpm6
KLA  ATP  ATP+KLA
 NM_153417 transient receptor potential cation channel, subfamily M, member 6 (Trpm6), mRNA [NM_153417] KLA .98 .99 .97 1.00 1.02 1.10 1.04
ATP .97 1.03 1.05 1.07 1.03 1.06 .98
KLA/ATP .99 .94 .98 1.07 1.09 1.01 1.03
Trpm7
KLA  ATP  ATP+KLA
 NM_021450 transient receptor potential cation channel, subfamily M, member 7 (Trpm7), mRNA [NM_021450] KLA 1.36 1.31 1.34 .98 .92 .79 .72
ATP .95 .84 .64 .58 .94 .90 .74
KLA/ATP 1.36 1.23 .85 .84 1.07 .93 .70
Trpv6
KLA  ATP  ATP+KLA
 NM_022413 transient receptor potential cation channel, subfamily V, member 6 (Trpv6), mRNA [NM_022413] KLA .97 .96 1.01 1.01 .99 .96 1.03
ATP 1.04 .99 .96 .99 1.01 1.00 .80
KLA/ATP 1.06 .99 1.02 1.01 .97 .97 .99
Vdr
KLA  ATP  ATP+KLA
 NM_009504 vitamin D receptor (Vdr), mRNA [NM_009504] KLA 1.01 1.01 1.12 1.12 1.09 .96 .94
ATP .99 1.03 1.09 1.19 1.25 1.24 1.36
KLA/ATP .99 1.03 1.03 1.28 1.21 1.42 1.76