Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Melanoma (mmu05218)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Akt1
KLA  ATP  ATP+KLA
 NM_009652 thymoma viral proto-oncogene 1 (Akt1), mRNA [NM_009652] KLA .80 .80 .75 .75 .71 .70 .82
ATP 1.00 1.02 .76 .85 .76 .68 .84
KLA/ATP .82 .80 .64 .68 .67 .61 .72
Akt2
KLA  ATP  ATP+KLA
 NM_007434 thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, mRNA [NM_007434] KLA 1.45 1.49 1.81 1.61 1.83 1.17 .92
ATP 1.12 1.12 1.00 1.28 1.20 .94 1.06
KLA/ATP 1.48 1.70 1.69 1.58 1.57 1.32 1.27
Akt3
KLA  ATP  ATP+KLA
 NM_011785 thymoma viral proto-oncogene 3 (Akt3), mRNA [NM_011785] KLA 3.42 3.45 5.31 5.16 4.65 3.80 2.12
ATP 1.12 1.22 1.10 1.37 1.02 1.11 1.56
KLA/ATP 3.72 4.17 4.62 4.64 2.74 2.05 3.82
Araf
KLA  ATP  ATP+KLA
 NM_009703 v-raf murine sarcoma 3611 viral oncogene homolog (Araf), mRNA [NM_009703] KLA .87 .80 .89 .93 1.10 1.19 1.16
ATP 1.09 1.11 1.19 1.18 .78 .53 1.18
KLA/ATP 1.00 .95 .99 .93 .63 .55 1.27
Bad
KLA  ATP  ATP+KLA
 AK029400 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4833429M11 product:Bcl-associated death promoter, full insert sequence. [AK029400] KLA 1.15 1.22 1.26 1.31 1.40 1.67 1.59
ATP .95 1.06 1.12 1.06 .78 .89 1.27
KLA/ATP 1.25 1.39 1.33 1.29 1.11 .91 1.38
Braf
KLA  ATP  ATP+KLA
 NM_139294 Braf transforming gene (Braf), mRNA [NM_139294] KLA 1.52 1.57 1.55 1.33 1.83 1.52 1.60
ATP 1.08 1.17 1.02 1.37 .95 1.15 .95
KLA/ATP 1.64 1.69 1.39 1.51 1.04 1.31 1.26
Ccnd1
KLA  ATP  ATP+KLA
 S78355 gb|Cyl-1=cyclin D1 [mice, BALB/c, brain, mRNA, 3737 nt]. [S78355] KLA .24 .23 .23 .24 .29 .47 .17
ATP 1.02 1.02 .88 .80 .52 .10 .21
KLA/ATP .27 .23 .22 .24 .27 .25 .14
Cdh1
KLA  ATP  ATP+KLA
 NM_009864 cadherin 1 (Cdh1), mRNA [NM_009864] KLA 1.03 1.03 .99 .94 .95 .97 .99
ATP 1.04 1.06 1.06 .96 .99 1.07 .95
KLA/ATP 1.02 1.07 1.00 .90 .93 .94 .98
Cdk4
KLA  ATP  ATP+KLA
 NM_009870 cyclin-dependent kinase 4 (Cdk4), mRNA [NM_009870] KLA .66 .72 .65 .55 .46 .50 .71
ATP 1.03 1.02 .53 .65 .66 .63 .75
KLA/ATP .78 .61 .31 .42 .44 .62 .43
Cdk6
KLA  ATP  ATP+KLA
 AK030810 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830411I20 product:unclassifiable, full insert sequence [AK030810] KLA 1.05 .96 .67 .51 .48 .49 .45
ATP 1.02 .91 .78 .49 .50 .47 .44
KLA/ATP 1.01 .89 .65 .40 .36 .26 .49
Cdk6
KLA  ATP  ATP+KLA
 NM_009873 cyclin-dependent kinase 6 (Cdk6), mRNA [NM_009873] KLA 2.63 2.36 2.14 1.80 1.55 1.32 1.03
ATP 1.11 1.21 1.06 1.23 .94 1.30 2.08
KLA/ATP 2.58 2.69 2.24 2.25 1.38 .85 3.00
Cdkn1a
KLA  ATP  ATP+KLA
 NM_007669 cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA [NM_007669] KLA 4.72 4.90 4.96 3.73 2.11 1.14 1.02
ATP 1.14 1.52 .95 1.69 1.47 2.21 .50
KLA/ATP 5.99 7.08 3.86 6.37 3.00 2.55 2.05
Cdkn2a
KLA  ATP  ATP+KLA
 NM_009877 cyclin-dependent kinase inhibitor 2A (Cdkn2a), transcript variant 1, mRNA [NM_009877] KLA .95 .95 .86 .96 .91 .90 .75
ATP 1.00 .99 .95 .95 .97 .89 .77
KLA/ATP .95 .96 .92 .94 .90 .85 .76
E2f1
KLA  ATP  ATP+KLA
 NM_007891 E2F transcription factor 1 (E2f1), mRNA [NM_007891] KLA .41 .44 .42 .41 .48 .77 .90
ATP 1.01 1.09 1.04 1.13 .83 .53 .84
KLA/ATP .44 .44 .52 .50 .49 .46 .85
E2f2
KLA  ATP  ATP+KLA
 NM_177733 E2F transcription factor 2 (E2f2), mRNA [NM_177733] KLA .13 .13 .14 .20 .19 .19 .18
ATP 1.08 .92 1.01 .85 .65 .38 .38
KLA/ATP .13 .13 .21 .20 .32 .24 .26
E2f3
KLA  ATP  ATP+KLA
 AK085296 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630007K21 product:E2F transcription factor 3, full insert sequence. [AK085296] KLA .98 .97 1.02 1.00 .99 .99 .99
ATP .97 1.06 1.03 .98 1.01 .99 1.00
KLA/ATP 1.12 1.14 1.03 .99 .96 .93 .96
E2f3
KLA  ATP  ATP+KLA
 NM_010093 E2F transcription factor 3 (E2f3), mRNA [NM_010093] KLA 1.11 1.09 1.13 1.21 1.47 1.62 1.65
ATP .97 .98 1.08 1.15 1.45 1.73 1.80
KLA/ATP 1.21 1.13 1.07 1.20 1.45 1.56 1.62
Egf
KLA  ATP  ATP+KLA
 NM_010113 epidermal growth factor (Egf), mRNA [NM_010113] KLA .89 .90 .81 .83 .83 .86 .92
ATP 1.03 1.03 .95 .84 .67 .79 .88
KLA/ATP .86 .86 .77 .77 .69 .78 .83
Egfr
KLA  ATP  ATP+KLA
 NM_007912 epidermal growth factor receptor (Egfr), transcript variant 2, mRNA [NM_007912] KLA 1.10 1.07 1.14 1.11 1.08 1.03 .90
ATP .99 1.00 1.04 .98 .97 1.15 1.14
KLA/ATP 1.07 1.10 1.16 1.08 1.01 .97 .94
Egfr
KLA  ATP  ATP+KLA
 NM_207655 epidermal growth factor receptor (Egfr), transcript variant 1, mRNA [NM_207655] KLA 1.57 1.44 1.47 1.31 .96 .92 .76
ATP .97 .93 1.10 1.00 1.41 2.97 .86
KLA/ATP 1.44 1.50 1.61 1.30 1.14 1.21 .82
Fgf1
KLA  ATP  ATP+KLA
 NM_010197 fibroblast growth factor 1 (Fgf1), mRNA [NM_010197] KLA 1.07 .99 .99 1.00 1.03 .97 .99
ATP 1.01 1.03 1.01 .95 .95 .98 .88
KLA/ATP 1.03 .99 .97 .99 .98 .94 1.01
Fgf10
KLA  ATP  ATP+KLA
 NM_008002 fibroblast growth factor 10 (Fgf10), mRNA [NM_008002] KLA .99 .98 1.02 1.00 1.02 1.02 1.02
ATP 1.03 1.02 1.00 1.00 1.00 .99 .99
KLA/ATP 1.01 1.00 1.04 .99 1.00 1.02 1.01
Fgf11
KLA  ATP  ATP+KLA
 BC066859 fibroblast growth factor 11, mRNA (cDNA clone MGC:76712 IMAGE:30101881), complete cds [BC066859] KLA .64 .61 .55 .58 .51 .48 .77
ATP 1.00 .96 .78 .78 .63 .44 .48
KLA/ATP .64 .63 .59 .56 .54 .42 .40
Fgf11
KLA  ATP  ATP+KLA
 NM_010198 fibroblast growth factor 11 (Fgf11), mRNA [NM_010198] KLA .99 1.02 1.05 1.04 1.01 1.03 1.07
ATP .95 1.02 1.02 1.07 .98 1.01 1.07
KLA/ATP 1.01 1.01 1.08 .96 .97 .95 1.01
Fgf12
KLA  ATP  ATP+KLA
 NM_183064 fibroblast growth factor 12 (Fgf12), transcript variant 1, mRNA [NM_183064] KLA .96 .97 1.05 .99 .97 1.01 1.01
ATP .93 .97 .97 .97 .99 .95 1.00
KLA/ATP 1.02 1.05 1.10 1.02 .95 1.01 .95
Fgf13
KLA  ATP  ATP+KLA
 NM_010200 fibroblast growth factor 13 (Fgf13), mRNA [NM_010200] KLA .91 .92 .93 .84 .77 .66 .75
ATP 1.09 1.14 1.03 1.11 1.06 .68 .78
KLA/ATP .98 1.02 .86 .90 .78 .70 .79
Fgf14
KLA  ATP  ATP+KLA
 NM_010201 fibroblast growth factor 14 (Fgf14), transcript variant 1, mRNA [NM_010201] KLA 1.04 1.05 1.02 1.04 1.03 1.05 1.03
ATP .99 1.08 1.04 1.00 .99 .98 1.04
KLA/ATP 1.00 1.00 1.08 1.00 1.04 1.01 1.03
Fgf14
KLA  ATP  ATP+KLA
 NM_207667 fibroblast growth factor 14 (Fgf14), transcript variant 2, mRNA [NM_207667] KLA 1.04 1.01 .98 .93 .96 .96 .97
ATP 1.04 1.10 .94 .87 1.03 .99 .96
KLA/ATP .86 .94 1.03 .89 1.00 .90 1.03
Fgf15
KLA  ATP  ATP+KLA
 NM_008003 fibroblast growth factor 15 (Fgf15), mRNA [NM_008003] KLA 1.00 1.00 .95 .98 .92 .96 1.01
ATP .99 1.01 .98 .98 .93 .95 .97
KLA/ATP .98 1.01 1.02 1.03 .97 .97 1.00
Fgf16
KLA  ATP  ATP+KLA
 NM_030614 fibroblast growth factor 16 (Fgf16), mRNA [NM_030614] KLA 1.00 .97 .99 1.02 1.04 .97 .97
ATP 1.02 .99 .99 1.02 1.12 1.01 1.02
KLA/ATP 1.06 1.02 .99 1.01 1.00 1.10 1.03
Fgf17
KLA  ATP  ATP+KLA
 NM_008004 fibroblast growth factor 17 (Fgf17), mRNA [NM_008004] KLA .97 1.03 .98 1.00 .97 .97 .86
ATP .99 .96 .99 .90 1.02 1.01 1.01
KLA/ATP .99 .91 1.08 .99 .99 .98 .99
Fgf18
KLA  ATP  ATP+KLA
 NM_008005 fibroblast growth factor 18 (Fgf18), mRNA [NM_008005] KLA 1.17 1.18 1.16 1.12 1.03 1.13 1.04
ATP .96 .98 2.47 12.57 2.76 1.56 1.03
KLA/ATP 1.01 1.15 2.33 10.13 2.80 1.79 1.02
Fgf2
KLA  ATP  ATP+KLA
 NM_008006 fibroblast growth factor 2 (Fgf2), mRNA [NM_008006] KLA 1.02 1.01 1.00 1.03 1.01 1.02 1.01
ATP .99 1.01 1.00 1.02 1.01 1.01 1.00
KLA/ATP 1.00 1.01 .98 1.01 1.02 1.03 1.01
Fgf20
KLA  ATP  ATP+KLA
 NM_030610 fibroblast growth factor 20 (Fgf20), mRNA [NM_030610] KLA .97 1.08 .99 1.00 .97 1.00 .97
ATP 1.03 .95 .97 1.05 .98 .97 1.00
KLA/ATP .99 .99 1.06 1.04 1.02 .92 .96
Fgf21
KLA  ATP  ATP+KLA
 NM_020013 fibroblast growth factor 21 (Fgf21), mRNA [NM_020013] KLA 1.02 1.03 .87 1.04 1.00 1.01 1.00
ATP 1.04 .97 1.00 1.02 .96 1.05 1.02
KLA/ATP 1.08 1.00 1.00 1.00 1.03 1.02 .99
Fgf22
KLA  ATP  ATP+KLA
 AK008922 adult male stomach cDNA, RIKEN full-length enriched library, clone:2210414E06 product:FIBROBLAST GROWTH FACTOR-22 PRECURSOR (FGF-22) homolog [Mus musculus], full insert sequence [AK008922] KLA .90 .94 .95 1.04 1.03 .94 .97
ATP 1.04 1.01 .98 .93 .93 .95 .88
KLA/ATP .98 .97 .97 1.01 .95 .92 .95
Fgf22
KLA  ATP  ATP+KLA
 NM_023304 fibroblast growth factor 22 (Fgf22), mRNA [NM_023304] KLA .99 .94 1.01 .95 .97 .89 .99
ATP 1.00 .95 1.00 .96 .97 .93 .98
KLA/ATP .91 1.00 1.01 .92 .95 .98 .97
Fgf23
KLA  ATP  ATP+KLA
 NM_022657 fibroblast growth factor 23 (Fgf23), mRNA [NM_022657] KLA 1.32 1.39 1.27 1.22 1.07 1.03 1.14
ATP .95 1.00 1.05 1.07 1.05 1.02 .96
KLA/ATP 1.32 1.39 1.37 1.22 1.01 1.00 .90
Fgf3
KLA  ATP  ATP+KLA
 NM_008007 fibroblast growth factor 3 (Fgf3), mRNA [NM_008007] KLA 1.03 1.05 1.00 .97 1.01 .98 .97
ATP 1.01 1.00 .97 1.03 .98 1.03 .97
KLA/ATP .98 1.00 1.01 1.03 1.03 1.00 .99
Fgf5
KLA  ATP  ATP+KLA
 NM_010203 fibroblast growth factor 5 (Fgf5), mRNA [NM_010203] KLA 1.02 1.02 1.00 1.03 .97 1.05 .99
ATP 1.02 1.00 1.03 .97 .99 .97 1.04
KLA/ATP 1.05 .92 1.01 1.00 1.11 .96 .97
Fgf6
KLA  ATP  ATP+KLA
 M92416 fibroblast growth factor (Fgf6) mRNA, 3 end [M92416] KLA 1.09 1.07 1.00 1.06 .97 1.01 .96
ATP 1.02 1.02 1.06 1.02 .93 .99 .98
KLA/ATP 1.04 .99 1.00 .99 1.00 1.00 1.03
Fgf6
KLA  ATP  ATP+KLA
 NM_010204 fibroblast growth factor 6 (Fgf6), mRNA [NM_010204] KLA 1.00 .96 1.06 .96 .96 1.00 .91
ATP .94 1.00 .89 .95 1.01 .92 1.00
KLA/ATP .99 1.06 1.06 .86 1.00 .95 1.00
Fgf7
KLA  ATP  ATP+KLA
 NM_008008 fibroblast growth factor 7 (Fgf7), mRNA [NM_008008] KLA 1.02 1.02 1.02 1.03 1.05 1.11 1.04
ATP 1.00 1.01 1.11 1.15 1.05 1.04 1.06
KLA/ATP .99 .96 .83 1.10 1.15 1.26 1.21
Fgf8
KLA  ATP  ATP+KLA
 BC048734 fibroblast growth factor 8, mRNA (cDNA clone MGC:59627 IMAGE:6513131), complete cds [BC048734] KLA .96 .95 1.03 .96 1.06 .97 .96
ATP 1.08 .94 1.07 1.10 1.00 .93 1.06
KLA/ATP 1.03 1.02 1.04 .96 1.04 .94 .94
Fgf8
KLA  ATP  ATP+KLA
 NM_010205 fibroblast growth factor 8 (Fgf8), mRNA [NM_010205] KLA 1.00 1.00 1.03 1.04 1.04 1.07 1.09
ATP 1.01 1.01 1.11 1.14 1.11 1.09 1.05
KLA/ATP 1.00 1.04 1.14 1.18 1.15 1.09 1.04
Fgf9
KLA  ATP  ATP+KLA
 NM_013518 fibroblast growth factor 9 (Fgf9), mRNA [NM_013518] KLA 1.04 1.07 1.07 1.12 .97 .96 .91
ATP 1.02 1.08 .98 1.00 .94 .99 .92
KLA/ATP 1.04 1.03 1.03 1.00 .93 .93 .89
Fgfr1
KLA  ATP  ATP+KLA
 M28998 gb|Mouse basic fibroblast growth factor receptor (bFGF-R) mRNA, complete cds. [M28998] KLA .82 .79 .73 .66 .50 .55 .65
ATP 1.01 1.08 .86 .90 1.29 1.24 1.52
KLA/ATP .85 .82 .71 .71 .63 .80 .85
Fgfr1
KLA  ATP  ATP+KLA
 NM_010206 fibroblast growth factor receptor 1 (Fgfr1), transcript variant 1, mRNA [NM_010206] KLA .92 .86 .73 .82 .79 .85 .84
ATP 1.01 1.06 .92 .92 1.18 1.02 1.22
KLA/ATP .83 .83 .79 .76 .83 .83 .92
Hgf
KLA  ATP  ATP+KLA
 AK033274 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030481P22 product:inferred: hepatocyte growth factor [AK033274] KLA 1.34 1.22 .96 .93 .82 .93 .87
ATP 1.64 2.45 3.30 1.89 .97 1.12 .90
KLA/ATP 1.49 2.50 3.96 1.88 1.07 1.00 .83
Hgf
KLA  ATP  ATP+KLA
 NM_010427 hepatocyte growth factor (Hgf), mRNA [NM_010427] KLA 1.11 1.18 1.30 1.20 1.08 .96 1.14
ATP 1.02 1.14 1.32 1.62 1.17 1.26 1.47
KLA/ATP 1.18 1.24 1.33 1.84 1.19 1.09 1.31
Hras1
KLA  ATP  ATP+KLA
 NM_008284 Harvey rat sarcoma virus oncogene 1 (Hras1), mRNA [NM_008284] KLA .79 .82 .77 .82 .94 1.03 1.07
ATP 1.01 .95 .69 .83 .79 1.12 1.15
KLA/ATP .84 .77 .61 .65 .82 1.00 1.05
Igf1
KLA  ATP  ATP+KLA
 AK050118 adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730016P09 product:unclassifiable, full insert sequence. [AK050118] KLA .13 .14 .15 .16 .22 .34 .48
ATP 1.78 2.05 1.37 .72 .34 .41 .58
KLA/ATP .24 .45 .50 .24 .20 .26 .68
Igf1
KLA  ATP  ATP+KLA
 NM_010512 insulin-like growth factor 1 (Igf1), transcript variant 1, mRNA [NM_010512] KLA .84 .78 .76 .67 .54 .48 .59
ATP .97 .98 1.13 1.13 1.03 .88 .89
KLA/ATP .82 .81 .93 .86 .83 .65 .89
Igf1
KLA  ATP  ATP+KLA
 NM_184052 insulin-like growth factor 1 (Igf1), transcript variant 2, mRNA [NM_184052] KLA .77 .82 .76 .65 .60 .52 .69
ATP 1.01 1.07 .98 1.06 1.03 .78 .94
KLA/ATP .89 .86 .77 .80 .75 .65 .89
Igf1r
KLA  ATP  ATP+KLA
 NM_010513 insulin-like growth factor I receptor (Igf1r), mRNA [NM_010513] KLA 1.32 1.32 1.08 .91 .55 .48 .45
ATP 1.03 1.06 1.06 1.29 1.31 1.45 .47
KLA/ATP 1.30 1.37 1.11 1.00 .93 1.02 .45
Kras
KLA  ATP  ATP+KLA
 NM_021284 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras), mRNA [NM_021284] KLA .53 .49 .40 .42 .49 .95 1.05
ATP .98 1.01 1.16 1.17 1.39 1.29 1.74
KLA/ATP .50 .47 .50 .56 1.00 1.24 1.58
Map2k1
KLA  ATP  ATP+KLA
 NM_008927 mitogen-activated protein kinase kinase 1 (Map2k1), mRNA [NM_008927] KLA 1.82 2.00 2.31 2.03 2.51 2.20 1.51
ATP .99 1.14 .81 .87 .90 1.57 1.11
KLA/ATP 1.90 2.03 1.50 1.93 1.63 2.03 2.06
Map2k2
KLA  ATP  ATP+KLA
 NM_023138 mitogen-activated protein kinase kinase 2 (Map2k2), mRNA [NM_023138] KLA .96 1.01 1.09 .99 1.11 1.15 1.42
ATP 1.07 1.05 .74 .86 1.04 1.16 1.21
KLA/ATP 1.14 1.03 .68 .78 .85 1.01 1.20
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mdm2
KLA  ATP  ATP+KLA
 NM_010786 transformed mouse 3T3 cell double minute 2 (Mdm2), mRNA [NM_010786] KLA 1.77 1.59 1.98 1.51 1.77 1.60 1.77
ATP 1.01 1.21 1.36 3.24 5.04 2.08 1.36
KLA/ATP 1.89 1.86 2.93 5.65 5.98 2.78 2.64
Met
KLA  ATP  ATP+KLA
 NM_008591 met proto-oncogene (Met), mRNA [NM_008591] KLA 3.56 3.71 3.68 3.79 4.24 5.89 6.95
ATP .98 .96 1.16 1.21 3.32 12.98 6.60
KLA/ATP 3.75 3.80 3.58 3.28 3.69 4.27 14.22
Mitf
KLA  ATP  ATP+KLA
 NM_008601 microphthalmia-associated transcription factor (Mitf), transcript variant 2, mRNA [NM_008601] KLA 2.09 2.20 1.58 2.38 2.33 2.27 1.52
ATP .93 .99 1.15 1.87 1.18 .89 1.16
KLA/ATP 1.83 2.28 2.35 2.87 1.26 .81 1.63
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.22094
6
KLA  ATP  ATP+KLA
 27545180 Unknown KLA 1.00 .93 .97 1.05 1.06 1.29 1.13
ATP .90 .94 1.25 1.18 .85 .62 1.20
KLA/ATP .86 .99 1.14 .99 .83 .70 1.26
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.27304
9
KLA  ATP  ATP+KLA
 119672895 Unknown KLA .23 .22 .22 .22 .30 .51 .16
ATP 1.08 1.05 .88 .78 .47 .09 .20
KLA/ATP .28 .22 .21 .24 .26 .22 .12
Mm.27574
2
KLA  ATP  ATP+KLA
 112983655 Unknown KLA 1.35 1.16 .94 .85 .45 .33 .31
ATP .90 .86 1.17 1.09 1.18 1.21 .38
KLA/ATP 1.12 1.22 1.19 .91 .90 .83 .33
Mm.30793
2
KLA  ATP  ATP+KLA
 160333363 Unknown KLA .13 .12 .14 .16 .15 .18 .15
ATP .92 .94 1.12 .93 .58 .29 .31
KLA/ATP .11 .11 .18 .20 .28 .20 .19
Mm.33981
2
KLA  ATP  ATP+KLA
 6679780 Unknown KLA 1.10 1.14 1.09 1.05 1.05 1.08 1.01
ATP .95 1.06 2.35 11.15 2.46 1.50 1.03
KLA/ATP 1.02 1.05 2.05 8.78 2.65 1.76 1.02
Mm.4387
KLA  ATP  ATP+KLA
 133892666 Unknown KLA .85 .87 .85 .89 .77 .91 1.18
ATP 1.01 1.01 .87 1.07 .75 .86 .93
KLA/ATP .88 .86 .77 .81 .72 .91 .84
Mm.47351
0
KLA  ATP  ATP+KLA
 162287332 Unknown KLA 4.46 4.82 5.29 4.00 2.26 1.25 1.10
ATP 1.24 1.72 1.02 2.08 1.66 2.53 .55
KLA/ATP 6.11 7.67 4.29 6.99 3.11 2.86 2.30
Mm.5055
KLA  ATP  ATP+KLA
 145966820 Unknown KLA 1.04 .96 1.04 .97 1.00 1.00 .97
ATP .95 .97 .96 .95 .97 .97 .98
KLA/ATP .88 1.04 1.07 1.02 .97 .98 .96
Nras
KLA  ATP  ATP+KLA
 NM_010937 neuroblastoma ras oncogene (Nras), mRNA [NM_010937] KLA 1.20 1.22 1.27 1.20 1.09 .91 .84
ATP .98 .91 .69 .61 .59 .67 .78
KLA/ATP 1.22 1.14 .97 .79 .73 .61 .72
Pdgfa
KLA  ATP  ATP+KLA
 NM_008808 platelet derived growth factor, alpha (Pdgfa), mRNA [NM_008808] KLA .63 .56 .42 .34 .31 .33 .52
ATP .89 .80 .69 1.23 5.97 3.99 2.73
KLA/ATP .64 .53 .43 .77 3.48 3.78 2.37
Pdgfb
KLA  ATP  ATP+KLA
 NM_011057 platelet derived growth factor, B polypeptide (Pdgfb), mRNA [NM_011057] KLA .45 .43 .38 .46 .69 .48 .58
ATP .94 .95 .66 .74 .67 .77 1.06
KLA/ATP .43 .43 .37 .39 .52 .55 1.64
Pdgfc
KLA  ATP  ATP+KLA
 AK081347 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130008P20 product:platelet-derived growth factor, C polypeptide, full insert sequence. [AK081347] KLA .93 1.07 1.00 1.03 .93 .95 .98
ATP 1.05 1.04 .94 1.02 1.04 1.00 1.05
KLA/ATP 1.06 1.02 .99 .96 .99 1.05 1.01
Pdgfc
KLA  ATP  ATP+KLA
 NM_019971 platelet-derived growth factor, C polypeptide (Pdgfc), mRNA [NM_019971] KLA 1.56 1.52 1.84 2.08 1.83 1.33 .79
ATP .98 .91 .86 .91 .78 1.43 3.28
KLA/ATP 1.45 1.50 1.25 1.73 1.99 1.56 1.12
Pdgfd
KLA  ATP  ATP+KLA
 AK141551 adult male hippocampus cDNA, RIKEN full-length enriched library, clone:C630020I23 product:platelet-derived growth factor, D polypeptide, full insert sequence [AK141551] KLA 1.07 1.01 1.06 .98 .94 1.00 1.00
ATP .98 .99 1.10 1.00 .96 1.00 .94
KLA/ATP 1.00 1.03 1.05 1.02 .94 .97 1.03
Pdgfd
KLA  ATP  ATP+KLA
 NM_027924 platelet-derived growth factor, D polypeptide (Pdgfd), mRNA [NM_027924] KLA .99 .93 .95 .97 1.00 .99 .95
ATP 1.01 .99 1.00 .93 1.05 1.04 1.06
KLA/ATP .91 .91 .96 .92 .92 .99 1.05
Pdgfra
KLA  ATP  ATP+KLA
 NM_011058 platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 1, mRNA [NM_011058] KLA 1.02 1.05 1.02 1.01 1.03 1.03 1.01
ATP 1.01 1.02 1.03 1.04 1.00 1.01 1.01
KLA/ATP 1.01 1.01 .99 1.03 1.02 1.03 1.01
Pdgfrb
KLA  ATP  ATP+KLA
 NM_008809 platelet derived growth factor receptor, beta polypeptide (Pdgfrb), mRNA [NM_008809] KLA 4.85 5.49 4.56 3.94 3.71 2.05 1.51
ATP .99 1.00 1.11 1.27 1.02 1.83 1.23
KLA/ATP 5.09 5.86 4.30 2.51 1.74 1.84 3.23
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Pten
KLA  ATP  ATP+KLA
 NM_008960 phosphatase and tensin homolog (Pten), mRNA [NM_008960] KLA .79 .73 .61 .59 .56 .70 1.00
ATP 1.04 1.11 1.07 1.12 1.03 1.38 .83
KLA/ATP .75 .69 .60 .74 .93 1.09 1.24
Raf1
KLA  ATP  ATP+KLA
 AK036317 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630056E02 product:v-raf-1 leukemia viral oncogene 1, full insert sequence. [AK036317] KLA 1.47 1.34 1.55 1.29 1.59 1.32 1.46
ATP 1.05 .98 .54 .63 3.32 2.07 1.01
KLA/ATP 1.57 1.33 .79 .96 2.26 1.38 1.35
Raf1
KLA  ATP  ATP+KLA
 NM_029780 v-raf-leukemia viral oncogene 1 (Raf1), mRNA [NM_029780] KLA 1.65 1.64 1.93 1.77 1.77 1.72 1.81
ATP .95 .96 .83 .80 2.22 2.92 1.19
KLA/ATP 1.68 1.64 1.39 1.32 1.85 2.50 2.06
Rb1
KLA  ATP  ATP+KLA
 NM_009029 retinoblastoma 1 (Rb1), mRNA [NM_009029] KLA .67 .60 .55 .51 .46 .75 .79
ATP 1.04 1.01 1.12 .86 .59 .43 .76
KLA/ATP .64 .59 .58 .46 .36 .30 .65
Trp53
KLA  ATP  ATP+KLA
 NM_011640 transformation related protein 53 (Trp53), mRNA [NM_011640] KLA 1.25 1.37 1.11 .86 .72 .71 .95
ATP 1.15 1.32 .90 1.85 1.26 .68 .70
KLA/ATP 1.66 1.49 .80 1.76 .81 .65 .74