Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Systemic lupus erythematosus (mmu05322)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
1700012L
04Rik
KLA  ATP  ATP+KLA
 NM_029588 RIKEN cDNA 1700012L04 gene (1700012L04Rik), mRNA [NM_029588] KLA .99 .98 .99 .98 .90 .94 .89
ATP 1.00 1.02 1.05 .97 .92 .97 .96
KLA/ATP .96 .95 .98 .91 .95 .92 1.00
1700014N
06Rik
KLA  ATP  ATP+KLA
 AK005982 adult male testis cDNA, RIKEN full-length enriched library, clone:1700014N06 product:HISTONE H2B, full insert sequence [AK005982] KLA .97 .96 1.05 1.06 1.01 1.00 1.00
ATP 1.01 1.03 1.03 .99 1.00 1.00 1.00
KLA/ATP .91 1.06 1.06 1.01 1.04 .96 .93
1700024P
04Rik
KLA  ATP  ATP+KLA
 BU938589 gb|AGENCOURT_10517723 NIH_MGC_169 Mus musculus cDNA clone IMAGE:6706749 5, mRNA sequence [BU938589] KLA .92 .86 .99 1.02 .96 .97 .99
ATP .95 .87 1.05 .99 .94 .97 .92
KLA/ATP .98 1.00 1.02 1.01 1.04 .88 .94
1700113O
17Rik
KLA  ATP  ATP+KLA
 NM_026627 RIKEN cDNA 1700113O17 gene (1700113O17Rik), mRNA [NM_026627] KLA .99 .99 .95 .96 1.01 .95 .98
ATP 1.06 1.24 1.21 1.11 .98 .97 .94
KLA/ATP .99 1.06 1.03 .94 .93 .94 .87
Actn1
KLA  ATP  ATP+KLA
 NM_134156 actinin, alpha 1 (Actn1), mRNA [NM_134156] KLA 1.33 1.42 1.46 1.16 1.18 .69 .54
ATP 1.06 1.13 .67 1.15 .95 .99 1.46
KLA/ATP 1.66 1.64 .81 1.55 .82 .78 .76
Actn2
KLA  ATP  ATP+KLA
 NM_033268 actinin alpha 2 (Actn2), mRNA [NM_033268] KLA 1.03 .94 1.02 1.05 1.02 1.06 1.11
ATP 1.04 .98 1.07 .99 1.10 1.03 1.02
KLA/ATP 1.06 1.03 .99 1.08 1.01 1.05 .98
Actn3
KLA  ATP  ATP+KLA
 NM_013456 actinin alpha 3 (Actn3), mRNA [NM_013456] KLA .97 .98 .98 .94 1.03 .96 1.07
ATP .95 .95 1.02 .98 .94 .95 1.01
KLA/ATP 1.05 1.03 .94 1.03 1.03 1.00 .95
Actn4
KLA  ATP  ATP+KLA
 NM_021895 actinin alpha 4 (Actn4), mRNA [NM_021895] KLA .78 .77 .75 .74 .58 .51 .65
ATP 1.03 1.03 1.21 1.14 1.50 1.30 1.09
KLA/ATP .78 .85 .96 .84 1.09 1.12 .97
AK015962
KLA  ATP  ATP+KLA
 AK015962 adult male testis cDNA, RIKEN full-length enriched library, clone:4930534G10 product:unclassifiable, full insert sequence. [AK015962] KLA 1.72 1.61 1.62 1.79 1.30 1.73 .70
ATP .81 .87 1.67 1.60 1.11 1.18 .78
KLA/ATP 1.28 1.54 2.72 2.59 2.32 1.92 1.61
C1qa
KLA  ATP  ATP+KLA
 NM_007572 complement component 1, q subcomponent, alpha polypeptide (C1qa), mRNA [NM_007572] KLA 1.12 1.11 1.09 .94 1.11 1.12 1.31
ATP 1.14 1.21 .88 1.16 .90 .67 .95
KLA/ATP 1.12 1.23 .93 1.27 .86 .81 .91
C1qb
KLA  ATP  ATP+KLA
 NM_009777 complement component 1, q subcomponent, beta polypeptide (C1qb), mRNA [NM_009777] KLA 1.01 1.14 1.20 1.15 1.31 1.15 1.06
ATP 1.16 1.20 .84 1.27 1.02 .70 .76
KLA/ATP 1.29 1.36 .95 1.28 1.00 .97 .85
C1qc
KLA  ATP  ATP+KLA
 NM_007574 complement component 1, q subcomponent, C chain (C1qc), mRNA [NM_007574] KLA 1.03 .97 1.01 1.04 1.07 1.13 1.15
ATP 1.07 1.06 .91 .94 .77 .62 .82
KLA/ATP 1.08 1.02 .95 1.04 .76 .73 .66
C1r
KLA  ATP  ATP+KLA
 NM_023143 complement component 1, r subcomponent (C1r), mRNA [NM_023143] KLA 8.09 7.91 7.94 8.52 7.04 6.64 3.85
ATP .96 .88 1.02 .92 .86 1.28 1.82
KLA/ATP 7.33 7.67 7.74 6.90 4.82 3.90 3.88
C1s
KLA  ATP  ATP+KLA
 NM_144938 complement component 1, s subcomponent (C1s), transcript variant 1, mRNA [NM_144938] KLA 1.32 1.25 1.42 1.28 1.26 1.18 1.22
ATP 1.00 1.04 1.04 1.06 1.02 1.12 1.21
KLA/ATP 1.34 1.30 1.19 1.19 1.15 1.18 1.21
C2
KLA  ATP  ATP+KLA
 NM_013484 complement component 2 (within H-2S) (C2), mRNA [NM_013484] KLA 1.84 2.05 2.15 2.41 2.47 2.93 3.16
ATP .96 .96 1.22 1.18 1.15 1.16 1.42
KLA/ATP 1.81 2.00 2.25 1.92 1.84 2.10 2.96
C3
KLA  ATP  ATP+KLA
 NM_009778 complement component 3 (C3), mRNA [NM_009778] KLA 28.58 25.57 24.39 27.34 23.38 23.21 18.10
ATP 1.04 .93 1.21 1.90 2.80 5.74 12.19
KLA/ATP 27.04 26.10 33.29 23.09 25.65 23.77 40.22
C4b
KLA  ATP  ATP+KLA
 NM_009780 complement component 4B (Childo blood group) (C4b), mRNA [NM_009780] KLA 1.46 1.50 1.67 1.58 1.87 1.68 1.33
ATP 1.05 .99 .95 .87 .88 .79 .66
KLA/ATP 1.39 1.62 1.52 1.32 1.36 1.03 .73
C6
KLA  ATP  ATP+KLA
 NM_016704 complement component 6 (C6), mRNA [NM_016704] KLA 1.04 .97 1.04 1.06 .98 1.04 .95
ATP 1.02 1.00 1.02 .96 1.01 .97 1.02
KLA/ATP .94 .95 1.07 1.05 .94 .94 .94
C8a
KLA  ATP  ATP+KLA
 NM_146148 complement component 8, alpha polypeptide (C8a), mRNA [NM_146148] KLA 1.02 1.02 .99 .96 1.06 1.03 1.01
ATP 1.05 1.10 1.00 1.00 .99 1.03 .98
KLA/ATP .98 1.00 1.02 .97 .92 .93 1.03
C8b
KLA  ATP  ATP+KLA
 NM_133882 complement component 8, beta subunit (C8b), mRNA [NM_133882] KLA .95 .96 .96 .95 1.00 .98 .98
ATP 1.07 .96 1.03 1.03 .96 .96 .90
KLA/ATP .99 1.05 1.03 .99 .96 1.03 .95
C8g
KLA  ATP  ATP+KLA
 NM_027062 complement component 8, gamma subunit (C8g), mRNA [NM_027062] KLA .89 .86 .85 .81 .74 .67 .90
ATP .94 .84 .79 .77 .63 .61 .82
KLA/ATP .85 .75 .74 .72 .62 .65 .81
C9
KLA  ATP  ATP+KLA
 NM_013485 complement component 9 (C9), mRNA [NM_013485] KLA 1.01 .95 1.00 1.03 1.01 1.05 1.07
ATP .96 .99 1.01 1.05 .98 1.04 1.06
KLA/ATP 1.00 .97 .94 1.01 1.11 1.05 1.13
Cd28
KLA  ATP  ATP+KLA
 NM_007642 CD28 antigen (Cd28), mRNA [NM_007642] KLA .52 .51 .45 .50 .36 .33 .18
ATP 1.11 1.26 1.08 1.25 1.99 1.42 2.08
KLA/ATP .51 .51 .58 .60 .56 .53 .38
Cd40
KLA  ATP  ATP+KLA
 NM_170701 CD40 antigen (Cd40), transcript variant 3, mRNA [NM_170701] KLA 23.87 23.62 23.26 23.98 22.07 17.37 5.34
ATP 1.00 1.01 1.06 2.96 2.65 3.03 1.70
KLA/ATP 22.77 23.79 29.67 28.85 28.08 21.62 13.02
Cd40lg
KLA  ATP  ATP+KLA
 NM_011616 CD40 ligand (Cd40lg), mRNA [NM_011616] KLA 1.03 1.07 1.02 .98 1.06 1.06 1.03
ATP .95 .92 .99 1.06 1.02 1.04 1.07
KLA/ATP 1.00 1.01 .93 1.04 .94 1.01 .98
Cd80
KLA  ATP  ATP+KLA
 NM_009855 CD80 antigen (Cd80), mRNA [NM_009855] KLA 2.13 1.91 1.89 1.78 1.29 1.00 .82
ATP .99 1.20 1.98 1.49 1.37 2.40 1.71
KLA/ATP 2.05 2.32 3.09 2.27 1.95 2.89 3.07
Cd86
KLA  ATP  ATP+KLA
 NM_019388 CD86 antigen (Cd86), mRNA [NM_019388] KLA 13.80 14.41 18.21 18.33 17.37 17.26 4.82
ATP 1.02 1.00 2.20 3.64 5.16 6.79 3.81
KLA/ATP 14.80 14.66 18.10 18.96 19.38 20.42 14.21
Ctsg
KLA  ATP  ATP+KLA
 NM_007800 cathepsin G (Ctsg), mRNA [NM_007800] KLA 1.15 1.23 1.36 1.24 1.14 1.09 1.22
ATP .97 1.04 1.19 1.22 1.30 1.19 .98
KLA/ATP 1.19 1.30 1.52 1.58 1.34 1.23 1.07
EG317677
KLA  ATP  ATP+KLA
 NM_173864 predicted gene, EG317677 (EG317677), mRNA [NM_173864] KLA .99 .99 1.01 1.01 .97 .98 1.06
ATP 1.00 1.01 1.05 1.05 .98 .99 1.01
KLA/ATP 1.00 1.00 .99 1.02 1.01 1.01 1.02
EG333452
KLA  ATP  ATP+KLA
 NM_001085517 predicted gene, EG333452 (EG333452), mRNA [NM_001085517] KLA .89 1.00 .93 .91 .92 1.01 .94
ATP 1.16 1.08 1.01 .98 .92 .97 .93
KLA/ATP .97 .96 .97 .95 .98 .98 .87
EG385328
KLA  ATP  ATP+KLA
 NM_001034100 predicted gene, EG385328 (EG385328), mRNA [NM_001034100] KLA .99 1.01 .92 .96 .93 .90 .96
ATP 1.07 1.02 1.04 1.04 .95 .90 .91
KLA/ATP .95 .88 .95 .83 .84 .88 .89
EG629860
KLA  ATP  ATP+KLA
 M17953 gb|Mouse Ig rearranged H-chain V-region mRNA VJ1 [M17953] KLA .96 1.05 1.03 1.08 1.08 1.02 .98
ATP .97 .99 1.05 1.10 .95 .94 .91
KLA/ATP .96 .94 .97 1.04 .97 1.01 .89
Ela2
KLA  ATP  ATP+KLA
 NM_015779 elastase 2, neutrophil (Ela2), mRNA [NM_015779] KLA .98 1.01 .91 .96 .94 .93 1.07
ATP 1.06 1.07 .94 1.07 1.00 .93 .96
KLA/ATP 1.16 1.08 .87 1.04 .98 1.01 1.02
Fcgr1
KLA  ATP  ATP+KLA
 AF143181 strain AB/H (Biozzi) high affinity immunoglobulin gamma Fc receptor I (Fcgr1) mRNA, Fcgr1-d allele, complete cds. [AF143181] KLA 4.27 4.21 5.59 6.14 8.13 9.76 10.98
ATP 1.23 1.12 1.08 1.36 1.09 2.09 11.81
KLA/ATP 4.56 4.93 4.95 5.88 6.66 9.64 23.09
Fcgr1
KLA  ATP  ATP+KLA
 NM_010186 Fc receptor, IgG, high affinity I (Fcgr1), mRNA [NM_010186] KLA 4.31 4.37 4.70 5.97 6.59 10.06 8.67
ATP 1.01 .88 1.16 .89 .90 2.15 9.23
KLA/ATP 4.01 4.10 5.52 4.54 6.31 9.24 15.83
Fcgr4
KLA  ATP  ATP+KLA
 NM_144559 Fc receptor, IgG, low affinity IV (Fcgr4), mRNA [NM_144559] KLA 9.03 8.68 9.82 11.51 11.12 13.01 7.95
ATP 1.04 .95 1.22 1.43 1.17 2.80 4.48
KLA/ATP 8.63 8.84 11.99 11.84 12.40 13.56 12.31
Grin2a
KLA  ATP  ATP+KLA
 NM_008170 glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a), mRNA [NM_008170] KLA 1.00 1.08 1.00 1.03 1.09 1.02 1.04
ATP .96 .94 1.00 .98 1.03 .97 1.01
KLA/ATP .95 1.02 1.03 .95 .99 .99 .95
Grin2b
KLA  ATP  ATP+KLA
 NM_008171 glutamate receptor, ionotropic, NMDA2B (epsilon 2) (Grin2b), mRNA [NM_008171] KLA 1.03 1.02 1.10 1.09 1.02 1.03 1.08
ATP 1.15 1.07 1.05 1.07 1.08 1.04 1.02
KLA/ATP 1.10 1.04 1.07 1.13 1.09 1.08 1.06
H2-Aa
KLA  ATP  ATP+KLA
 NM_010378 histocompatibility 2, class II antigen A, alpha (H2-Aa), mRNA [NM_010378] KLA 1.43 1.59 1.68 1.50 1.62 1.89 1.64
ATP 1.07 1.15 1.27 1.90 1.92 1.77 1.55
KLA/ATP 1.62 1.81 1.74 2.29 1.89 1.92 2.19
H2-Ab1
KLA  ATP  ATP+KLA
 BC010322 histocompatibility 2, class II antigen A, beta 1, mRNA (cDNA clone MGC:6297 IMAGE:2651058), complete cds [BC010322] KLA 1.73 1.76 1.77 1.55 1.95 2.10 2.27
ATP 1.03 1.18 1.32 1.99 1.79 1.56 1.61
KLA/ATP 1.70 2.01 1.74 2.52 1.58 2.01 2.75
H2-Ab1
KLA  ATP  ATP+KLA
 NM_207105 histocompatibility 2, class II antigen A, beta 1 (H2-Ab1), mRNA [NM_207105] KLA 2.02 2.15 2.07 2.09 2.32 2.78 3.08
ATP 1.11 1.20 1.42 2.33 2.33 2.25 1.87
KLA/ATP 2.11 2.32 2.52 3.62 2.67 2.96 5.04
H2afj
KLA  ATP  ATP+KLA
 NM_177688 H2A histone family, member J (H2afj), mRNA [NM_177688] KLA .51 .52 .62 .67 .65 .67 .58
ATP .94 .85 .94 .91 .80 .76 .56
KLA/ATP .51 .46 .59 .80 .90 .86 .77
H2afx
KLA  ATP  ATP+KLA
 NM_010436 H2A histone family, member X (H2afx), mRNA [NM_010436] KLA .25 .24 .21 .24 .22 .30 .32
ATP 1.08 1.16 1.97 3.00 2.74 1.21 .31
KLA/ATP .27 .27 .63 1.77 2.44 1.33 .35
H2afy
KLA  ATP  ATP+KLA
 NM_012015 H2A histone family, member Y (H2afy), mRNA [NM_012015] KLA 1.89 1.87 1.99 1.91 2.31 1.63 1.06
ATP 1.14 1.13 .62 .95 .66 .60 .92
KLA/ATP 1.94 2.10 1.34 2.00 1.20 1.02 .97
H2afy2
KLA  ATP  ATP+KLA
 NM_207000 H2A histone family, member Y2 (H2afy2), mRNA [NM_207000] KLA 1.00 1.02 .96 1.04 1.09 1.06 .96
ATP 1.08 1.02 .93 .95 1.02 .96 1.20
KLA/ATP 1.04 .98 .90 .99 1.05 1.10 1.11
H2afz
KLA  ATP  ATP+KLA
 AK044932 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130014G07 product:H2A histone family, member Z, full insert sequence [AK044932] KLA 1.00 1.01 .93 .97 .94 1.00 1.01
ATP 1.03 1.05 1.03 .98 .97 1.09 1.02
KLA/ATP .96 .98 .97 .97 .97 1.03 1.10
H2afz
KLA  ATP  ATP+KLA
 NM_016750 H2A histone family, member Z (H2afz), mRNA [NM_016750] KLA 1.10 1.20 1.23 1.25 .99 .68 .41
ATP 1.00 .98 1.27 1.50 1.65 1.55 .47
KLA/ATP 1.10 1.13 1.18 1.36 1.58 1.54 .58
H2-DMa
KLA  ATP  ATP+KLA
 NM_010386 histocompatibility 2, class II, locus DMa (H2-DMa), mRNA [NM_010386] KLA 1.49 1.50 1.65 1.65 1.91 2.23 1.69
ATP 1.04 1.12 1.26 1.67 1.24 .99 1.32
KLA/ATP 1.58 1.68 1.70 2.02 1.37 1.35 1.90
H2-DMb1
KLA  ATP  ATP+KLA
 NM_010387 histocompatibility 2, class II, locus Mb1 (H2-DMb1), mRNA [NM_010387] KLA 1.06 1.14 1.08 1.13 1.24 1.41 1.37
ATP 1.01 1.02 1.09 1.14 .92 .73 1.36
KLA/ATP 1.13 1.05 1.21 1.17 .98 .83 1.41
H2-DMb2
KLA  ATP  ATP+KLA
 NM_010388 histocompatibility 2, class II, locus Mb2 (H2-DMb2), mRNA [NM_010388] KLA 1.00 1.04 .93 .95 .96 .95 1.03
ATP 1.06 1.04 .94 .92 .97 .95 1.00
KLA/ATP .90 .94 .99 .94 .90 .96 .92
H2-Eb1
KLA  ATP  ATP+KLA
 X52641 gb|Mouse mRNA for I-A beta NOD. [X52641] KLA 1.94 2.06 1.94 1.87 1.96 2.18 1.76
ATP 1.11 1.20 1.53 2.70 3.02 2.91 1.40
KLA/ATP 2.09 2.11 2.26 3.55 2.76 3.05 3.05
H2-Oa
KLA  ATP  ATP+KLA
 NM_008206 histocompatibility 2, O region alpha locus (H2-Oa), mRNA [NM_008206] KLA 1.22 1.32 1.37 1.33 1.31 1.26 1.53
ATP 1.02 1.05 1.16 1.21 1.12 1.07 1.16
KLA/ATP 1.32 1.34 1.31 1.34 1.25 1.35 2.78
H2-Ob
KLA  ATP  ATP+KLA
 NM_010389 histocompatibility 2, O region beta locus (H2-Ob), mRNA [NM_010389] KLA 1.05 1.07 1.01 .96 1.10 1.02 1.00
ATP 1.04 .99 1.00 1.03 .94 1.07 .94
KLA/ATP 1.02 .97 1.06 1.08 1.00 .96 1.05
H3f3a
KLA  ATP  ATP+KLA
 NM_008210 H3 histone, family 3A (H3f3a), mRNA [NM_008210] KLA 1.06 1.08 1.16 1.19 1.21 1.49 1.57
ATP .99 .99 1.28 1.21 1.52 1.81 .78
KLA/ATP .91 .92 1.42 1.41 1.97 2.07 1.27
H3f3b
KLA  ATP  ATP+KLA
 NM_008211 H3 histone, family 3B (H3f3b), mRNA [NM_008211] KLA 2.30 2.24 2.39 2.46 2.24 2.79 1.50
ATP .85 .87 2.00 2.47 1.89 1.71 .93
KLA/ATP 2.10 2.17 3.76 4.47 4.37 3.19 2.20
Hc
KLA  ATP  ATP+KLA
 NM_010406 hemolytic complement (Hc), mRNA [NM_010406] KLA 1.07 1.12 1.05 .98 1.12 1.12 1.08
ATP .96 .93 1.12 1.07 1.34 5.60 1.48
KLA/ATP 1.05 1.18 1.12 1.05 1.13 3.40 4.37
Hist1h2a
a
KLA  ATP  ATP+KLA
 NM_175658 histone cluster 1, H2aa (Hist1h2aa), mRNA [NM_175658] KLA .38 .41 .42 .42 .37 .44 .30
ATP .98 .97 1.27 1.05 .64 .64 .50
KLA/ATP .39 .38 .55 .57 .50 .58 .75
Hist1h2a
b
KLA  ATP  ATP+KLA
 NM_175660 histone cluster 1, H2ab (Hist1h2ab), mRNA [NM_175660] KLA .47 .46 .43 .42 .33 .38 .27
ATP .88 1.02 1.85 1.55 .78 .46 .32
KLA/ATP .41 .50 .65 .64 .49 .40 .38
Hist1h2a
c
KLA  ATP  ATP+KLA
 NM_178189 histone cluster 1, H2ac (Hist1h2ac), mRNA [NM_178189] KLA 1.01 .92 .99 .98 .95 1.00 1.08
ATP .97 1.04 1.41 2.00 1.18 1.04 .95
KLA/ATP .93 .97 1.06 1.37 1.06 1.00 1.08
Hist1h2a
e
KLA  ATP  ATP+KLA
 NM_178187 histone cluster 1, H2ae (Hist1h2ae), mRNA [NM_178187] KLA .96 1.05 1.02 .99 .92 .94 .88
ATP 1.02 1.19 2.03 2.39 1.94 1.77 1.40
KLA/ATP .91 1.09 1.22 1.32 1.34 1.08 .91
Hist1h2a
f
KLA  ATP  ATP+KLA
 NM_175661 histone cluster 1, H2af (Hist1h2af), mRNA [NM_175661] KLA .34 .36 .33 .32 .27 .32 .19
ATP .94 1.02 1.45 1.09 .66 .52 .32
KLA/ATP .33 .32 .51 .50 .38 .42 .47
Hist1h2a
i
KLA  ATP  ATP+KLA
 NM_178182 histone cluster 1, H2ai (Hist1h2ai), mRNA [NM_178182] KLA .44 .43 .43 .40 .33 .38 .22
ATP .84 .90 1.57 1.33 .75 .62 .30
KLA/ATP .38 .41 .70 .67 .55 .54 .41
Hist1h2a
k
KLA  ATP  ATP+KLA
 NM_178183 histone cluster 1, H2ak (Hist1h2ak), mRNA [NM_178183] KLA .34 .38 .37 .30 .25 .28 .16
ATP .87 .93 1.55 1.24 .68 .52 .25
KLA/ATP .34 .33 .52 .56 .42 .41 .35
Hist1h2b
a
KLA  ATP  ATP+KLA
 NM_175663 histone cluster 1, H2ba (Hist1h2ba), mRNA [NM_175663] KLA 1.02 .98 .79 .95 .80 1.30 2.48
ATP 1.08 .95 1.96 3.71 4.00 4.55 2.49
KLA/ATP .97 .88 1.87 2.92 3.78 3.95 3.51
Hist1h2b
c
KLA  ATP  ATP+KLA
 NM_023422 histone cluster 1, H2bc (Hist1h2bc), mRNA [NM_023422] KLA .91 .87 .80 .86 .74 1.35 2.94
ATP 1.00 .83 1.89 4.30 4.12 4.38 2.35
KLA/ATP 1.07 .82 1.29 2.92 3.55 4.37 4.26
Hist1h2b
e
KLA  ATP  ATP+KLA
 NM_178194 histone cluster 1, H2be (Hist1h2be), mRNA [NM_178194] KLA .91 1.00 1.00 1.01 .91 1.06 1.13
ATP 1.02 1.07 1.09 1.04 .99 1.02 1.00
KLA/ATP 1.06 1.01 1.06 1.09 1.04 1.03 1.06
Hist1h2b
k
KLA  ATP  ATP+KLA
 NM_175665 histone cluster 1, H2bk (Hist1h2bk), mRNA [NM_175665] KLA .88 .91 .82 .88 .75 1.25 2.49
ATP .97 .83 2.07 3.65 3.58 3.77 2.19
KLA/ATP .94 .81 1.52 2.51 3.36 3.76 3.20
Hist1h2b
m
KLA  ATP  ATP+KLA
 NM_178200 histone cluster 1, H2bm (Hist1h2bm), mRNA [NM_178200] KLA .88 .90 .80 .81 .68 1.18 2.48
ATP .94 .86 2.00 3.59 3.39 3.57 2.23
KLA/ATP .91 .80 1.42 2.43 3.16 3.54 3.19
Hist1h2b
p
KLA  ATP  ATP+KLA
 AK076671 adult male testis cDNA, RIKEN full-length enriched library, clone:4930408P03 product:HISTONE H2B (FRAGMENT) homolog [Mus musculus], full insert sequence. [AK076671] KLA .84 .87 .93 .94 .85 .92 1.04
ATP .97 .91 1.23 1.40 1.02 .80 .91
KLA/ATP .87 .82 .88 .95 .92 .87 .88
Hist1h3a
KLA  ATP  ATP+KLA
 NM_013550 histone cluster 1, H3a (Hist1h3a), mRNA [NM_013550] KLA .86 .91 1.03 1.06 .96 .97 .95
ATP .97 1.14 2.05 3.06 2.48 2.55 1.19
KLA/ATP .92 1.04 1.38 1.85 1.82 1.79 1.27
Hist1h3d
KLA  ATP  ATP+KLA
 NM_178204 histone cluster 1, H3d (Hist1h3d), mRNA [NM_178204] KLA 2.02 2.07 2.29 2.29 2.12 2.54 1.63
ATP 1.00 .98 1.54 2.39 2.20 2.14 1.36
KLA/ATP 2.02 2.20 3.05 4.09 4.58 3.59 3.12
Hist1h4a
KLA  ATP  ATP+KLA
 NM_178192 histone cluster 1, H4a (Hist1h4a), mRNA [NM_178192] KLA .83 .88 .73 .73 .54 .67 .40
ATP .78 .91 2.28 2.85 1.76 1.53 .74
KLA/ATP .66 .73 1.64 1.84 1.35 1.15 .74
Hist1h4d
KLA  ATP  ATP+KLA
 NM_175654 histone cluster 1, H4d (Hist1h4d), mRNA [NM_175654] KLA .77 .78 .64 .59 .42 .53 .29
ATP .83 .90 1.97 2.16 1.33 1.09 .55
KLA/ATP .61 .63 1.19 1.24 .78 .67 .49
Hist1h4f
KLA  ATP  ATP+KLA
 NM_175655 histone cluster 1, H4f (Hist1h4f), mRNA [NM_175655] KLA .67 .71 .59 .53 .38 .48 .29
ATP .79 .86 1.99 2.30 1.46 1.29 .66
KLA/ATP .55 .56 1.07 1.17 .84 .86 .63
Hist1h4i
KLA  ATP  ATP+KLA
 BF467941 gb|UI-M-CC0-ayb-f-07-0-UI.r1 NIH_BMAP_Ret1 Mus musculus cDNA clone UI-M-CC0-ayb-f-07-0-UI 5. [BF467941] KLA 1.10 1.11 1.14 1.22 .92 1.30 1.57
ATP .67 .79 4.06 5.43 4.86 5.73 3.17
KLA/ATP .99 1.23 3.46 3.53 4.21 3.78 5.09
Hist2h2a
a1
KLA  ATP  ATP+KLA
 AK028129 adult male stomach cDNA, RIKEN full-length enriched library, clone:2210403F13 product:histone gene complex 2, full insert sequence [AK028129] KLA .73 .78 .80 .68 .81 .91 .97
ATP .99 1.00 .90 .80 .62 .67 .90
KLA/ATP .78 .76 .70 .64 .72 .65 .77
Hist2h2a
a1
KLA  ATP  ATP+KLA
 NM_013549 histone cluster 2, H2aa1 (Hist2h2aa1), mRNA [NM_013549] KLA .93 1.09 1.23 1.22 1.12 1.24 1.42
ATP .97 1.03 1.48 1.83 1.59 1.99 2.88
KLA/ATP .96 1.14 1.56 1.84 1.67 2.45 6.50
Hist2h2a
c
KLA  ATP  ATP+KLA
 NM_175662 histone cluster 2, H2ac (Hist2h2ac), mRNA [NM_175662] KLA .43 .46 .46 .43 .40 .45 .32
ATP .95 1.02 1.18 1.11 .71 .70 .54
KLA/ATP .41 .41 .56 .61 .55 .64 .83
Hist2h2b
b
KLA  ATP  ATP+KLA
 BC019122 histone cluster 2, H2bb, mRNA (cDNA clone MGC:29103 IMAGE:5003093), complete cds [BC019122] KLA .98 1.08 1.07 1.07 1.10 1.16 1.08
ATP .89 .87 1.96 5.64 2.29 1.19 1.03
KLA/ATP 1.02 .98 1.69 5.25 2.33 1.47 1.29
Hist2h2b
e
KLA  ATP  ATP+KLA
 NM_178214 histone cluster 2, H2be (Hist2h2be), mRNA [NM_178214] KLA .94 .96 .86 .71 .69 1.19 .98
ATP .76 .68 1.00 .72 .61 .83 1.16
KLA/ATP 1.22 1.01 2.41 3.18 3.20 2.00 1.97
Hist2h3c
1
KLA  ATP  ATP+KLA
 NM_178216 histone cluster 2, H3c1 (Hist2h3c1), transcript variant 2, mRNA [NM_178216] KLA 1.98 2.04 2.22 2.28 2.10 2.55 1.66
ATP .95 .90 1.44 2.09 1.84 2.00 1.40
KLA/ATP 1.94 1.90 3.07 3.84 4.33 3.44 3.00
Hist2h4
KLA  ATP  ATP+KLA
 NM_033596 histone cluster 2, H4 (Hist2h4), mRNA [NM_033596] KLA .77 .79 .68 .60 .41 .51 .29
ATP .83 .93 2.16 2.49 1.59 1.44 .65
KLA/ATP .64 .64 1.32 1.39 1.00 .92 .63
Hist3h2a
KLA  ATP  ATP+KLA
 NM_178218 histone cluster 3, H2a (Hist3h2a), mRNA [NM_178218] KLA .78 .80 .81 .93 .83 .91 .54
ATP 1.03 1.05 1.42 1.32 1.06 1.04 .67
KLA/ATP .72 .80 1.31 1.31 1.26 1.48 1.41
Hist3h2b
a
KLA  ATP  ATP+KLA
 NM_030082 histone cluster 3, H2ba (Hist3h2ba), mRNA [NM_030082] KLA .84 .93 .98 .92 .87 1.37 1.55
ATP .91 .91 1.41 1.22 .93 .84 .85
KLA/ATP .80 .83 1.14 1.11 .97 2.07 7.01
Hist3h2b
b
KLA  ATP  ATP+KLA
 NM_206882 histone cluster 3, H2bb (Hist3h2bb), mRNA [NM_206882] KLA 1.01 .93 .83 .90 .79 1.25 2.56
ATP 1.10 .97 2.03 3.38 3.78 3.89 2.43
KLA/ATP 1.04 .89 1.63 2.55 3.35 3.88 3.43
Hist4h4
KLA  ATP  ATP+KLA
 AK045187 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130044J01 product:H4 HISTONE homolog [Homo sapiens], full insert sequence [AK045187] KLA .96 .90 1.02 1.03 .97 1.01 1.03
ATP 1.01 1.07 .97 .99 .95 1.01 1.00
KLA/ATP 1.00 1.13 .97 1.04 1.03 1.00 .98
Hist4h4
KLA  ATP  ATP+KLA
 NM_175652 histone cluster 4, H4 (Hist4h4), mRNA [NM_175652] KLA .81 .87 .69 .76 .54 .67 .40
ATP .84 .92 2.25 2.71 1.64 1.51 .72
KLA/ATP .69 .75 1.53 1.74 1.28 1.08 .80
Ifng
KLA  ATP  ATP+KLA
 NM_008337 interferon gamma (Ifng), mRNA [NM_008337] KLA 1.05 1.02 1.01 1.01 1.01 1.04 1.00
ATP 1.00 1.01 1.01 .98 .97 1.04 1.03
KLA/ATP 1.01 1.01 1.06 1.10 1.24 1.10 1.04
Igh-VJ55
8
KLA  ATP  ATP+KLA
 AY547436 immunoglobulin heavy chain VDJ region mRNA, partial cds [AY547436] KLA 1.06 1.05 1.01 .93 1.03 .96 .93
ATP .99 1.00 1.06 .95 .96 1.06 1.05
KLA/ATP .98 .94 1.07 .95 .97 .99 1.02
Igh-VJ55
8
KLA  ATP  ATP+KLA
 CA578712 gb|K0727F04-5N NIA Mouse Hematopoietic Stem Cell (Lin- [CA578712] KLA .99 .94 1.01 1.10 .93 .97 .92
ATP .93 1.04 1.01 .98 1.05 .96 .95
KLA/ATP .99 .95 .95 .98 1.02 .98 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103412 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHA] [ENSMUST00000103412] KLA 1.01 .97 1.20 1.01 .98 1.44 1.24
ATP .99 .98 1.07 1.03 1.00 1.01 1.21
KLA/ATP .99 1.02 .96 1.03 .97 1.13 1.30
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103413 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHE] [ENSMUST00000103413] KLA 1.00 .99 1.06 1.06 .99 1.03 1.02
ATP 1.08 1.06 1.06 1.06 1.02 1.06 .95
KLA/ATP 1.00 1.04 1.09 1.02 1.06 1.02 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 U39781 J558+ IgM heavy chain mRNA, hybridoma clone ME2B7, partial cds. [U39781] KLA .93 .89 .98 .97 1.03 1.00 .94
ATP 1.04 1.02 1.08 .94 .93 .90 .79
KLA/ATP .88 .89 .97 .93 .88 .92 .82
Il10
KLA  ATP  ATP+KLA
 NM_010548 interleukin 10 (Il10), mRNA [NM_010548] KLA 17.59 18.64 22.22 23.06 11.83 8.27 2.07
ATP 1.86 3.22 7.72 20.51 25.86 8.38 1.01
KLA/ATP 17.91 23.49 34.53 34.48 20.98 12.03 8.17
Mm.19763
8
KLA  ATP  ATP+KLA
 22122666 Unknown KLA .93 1.02 .99 .99 1.03 1.02 1.04
ATP 1.01 1.00 1.05 .88 .98 .98 1.01
KLA/ATP 1.03 1.01 1.00 .97 1.00 1.07 .96
Mm.21254
9
KLA  ATP  ATP+KLA
 142376228 Unknown KLA 2.23 2.18 2.36 2.57 2.10 2.61 1.52
ATP .80 .75 1.25 1.46 .96 1.40 1.18
KLA/ATP 1.46 1.62 2.46 2.73 1.74 2.50 3.29
Mm.25500
3
KLA  ATP  ATP+KLA
 161484596 Unknown KLA .35 .34 .35 .34 .22 .19 .10
ATP 1.09 1.27 1.13 1.29 2.25 1.66 2.22
KLA/ATP .38 .36 .39 .40 .49 .42 .32
Mm.26167
0
KLA  ATP  ATP+KLA
 20799906 Unknown KLA 1.01 1.04 .98 1.06 .90 1.23 2.47
ATP .85 .93 1.41 1.52 1.34 2.12 5.55
KLA/ATP .96 1.01 1.34 1.73 1.67 2.60 10.21
Mm.27568
1
KLA  ATP  ATP+KLA
 77539461 Unknown KLA .93 .88 .93 .99 .92 .96 .92
ATP 1.05 1.03 1.05 .91 .97 1.02 .88
KLA/ATP .96 .93 .94 .90 .88 .84 .91
Mm.27604
2
KLA  ATP  ATP+KLA
 18702319 Unknown KLA .81 .72 .70 .70 .54 .54 .67
ATP .90 .95 1.17 1.15 1.35 1.32 1.13
KLA/ATP .70 .78 .89 .83 1.09 1.13 .97
Mm.32122
7
KLA  ATP  ATP+KLA
 127139523 Unknown KLA 12.52 10.89 10.68 9.49 5.40 5.25 1.79
ATP .99 .85 .90 .47 .56 3.75 1.90
KLA/ATP 11.44 9.85 11.83 8.16 9.82 10.41 7.47
Mm.35895
4
KLA  ATP  ATP+KLA
 30089709 Unknown KLA .40 .41 .42 .41 .37 .44 .28
ATP .87 .95 1.25 1.06 .68 .67 .49
KLA/ATP .36 .38 .55 .57 .52 .61 .73
Mm.35895
5
KLA  ATP  ATP+KLA
 30089703 Unknown KLA .90 .90 .87 .84 .75 1.22 2.50
ATP 1.06 .91 2.11 3.91 3.77 4.01 2.40
KLA/ATP 1.03 .86 1.54 2.57 3.56 3.79 3.54
Mm.37176
6
KLA  ATP  ATP+KLA
 160420311 Unknown KLA .49 .34 .80 .82 .87 1.14 1.04
ATP .43 .30 1.42 1.53 .98 3.32 1.63
KLA/ATP .38 .20 .99 1.14 1.03 2.63 1.63
Mm.37789
8
KLA  ATP  ATP+KLA
 46049028 Unknown KLA 1.08 1.00 1.07 1.02 1.10 .95 .96
ATP .98 .98 1.01 1.01 .89 1.07 1.05
KLA/ATP .95 1.00 1.13 1.00 .97 .99 1.03
Mm.39284
3
KLA  ATP  ATP+KLA
 118129857 Unknown KLA 1.02 1.15 .83 1.12 .78 .83 .81
ATP .77 1.08 1.11 1.18 .98 .89 .57
KLA/ATP .91 1.20 1.39 1.13 1.17 .84 .53
Mm.42268
0
KLA  ATP  ATP+KLA
 9506766 Unknown KLA 2.08 2.13 2.15 2.32 2.08 2.61 1.60
ATP .92 .92 1.55 2.40 2.08 2.17 1.45
KLA/ATP 1.95 2.02 3.30 4.29 4.84 3.79 3.35
Mm.44230
7
KLA  ATP  ATP+KLA
 30061354 Unknown KLA .68 .77 .60 .53 .36 .48 .29
ATP .76 .92 2.12 2.50 1.62 1.40 .68
KLA/ATP .59 .60 1.18 1.38 .95 .89 .66
Mm.45107
1
KLA  ATP  ATP+KLA
 68226432 Unknown KLA .96 1.04 .99 1.06 .87 1.37 2.42
ATP .96 .86 2.23 3.91 3.43 3.57 2.09
KLA/ATP 1.01 .96 1.81 2.89 3.45 3.52 2.98
Mm.47367
1
KLA  ATP  ATP+KLA
 149270962 Unknown KLA .99 .98 .94 .95 .84 .91 .93
ATP 1.04 1.00 1.07 .96 .85 .94 .98
KLA/ATP 1.01 .88 .89 .90 .94 .92 .78
Mm.874
KLA  ATP  ATP+KLA
 6754317 Unknown KLA 24.98 24.87 26.43 39.61 12.88 8.64 1.63
ATP 1.97 3.50 11.05 28.47 38.30 10.44 .65
KLA/ATP 23.45 29.37 58.52 51.77 30.64 14.61 8.63
RP23-38E
20.1
KLA  ATP  ATP+KLA
 NM_001097979 H2b histone family, member A (LOC665596), mRNA [NM_001097979] KLA .72 .54 .87 .92 .94 1.01 1.10
ATP .67 .52 1.08 1.27 .94 1.78 1.24
KLA/ATP .69 .38 .87 1.15 .98 1.46 1.21
Snrpb
KLA  ATP  ATP+KLA
 NM_009225 small nuclear ribonucleoprotein B (Snrpb), mRNA [NM_009225] KLA 1.04 1.15 1.10 .93 1.04 .79 .73
ATP 1.13 1.30 .93 1.39 1.06 .86 .72
KLA/ATP 1.27 1.24 .83 1.57 .96 .81 .63
Snrpd1
KLA  ATP  ATP+KLA
 AK017788 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730525N20 product:small nuclear ribonucleoprotein D1, full insert sequence. [AK017788] KLA 1.12 1.03 1.02 1.02 .99 .96 1.01
ATP 1.11 1.05 1.14 1.03 1.07 1.21 1.05
KLA/ATP .91 1.06 1.18 1.06 1.00 1.03 1.14
Snrpd1
KLA  ATP  ATP+KLA
 NM_009226 small nuclear ribonucleoprotein D1 (Snrpd1), mRNA [NM_009226] KLA 1.10 1.05 .92 .94 .76 .73 .68
ATP 1.00 .98 1.18 1.10 .98 .90 .49
KLA/ATP .90 1.03 1.21 1.03 .92 .70 .39
Snrpd3
KLA  ATP  ATP+KLA
 NM_026095 small nuclear ribonucleoprotein D3 (Snrpd3), mRNA [NM_026095] KLA 1.00 1.09 .86 1.16 .77 .87 .86
ATP .77 1.06 1.12 1.18 .96 .87 .59
KLA/ATP .92 1.16 1.43 1.14 1.18 .82 .58
Ssb
KLA  ATP  ATP+KLA
 AK088370 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430014C08 product:Sjogren syndrome antigen B, full insert sequence. [AK088370] KLA 1.00 .93 .95 .97 .94 1.03 .93
ATP 1.03 .98 .94 .87 .99 1.02 .93
KLA/ATP .91 .98 .90 .97 .96 .91 .92
Ssb
KLA  ATP  ATP+KLA
 L00993 autoantigen La (SS-B) mRNA, complete cds. [L00993] KLA 1.25 1.19 1.16 1.18 .92 .85 .89
ATP .93 .96 1.37 1.22 1.05 1.13 .80
KLA/ATP 1.09 1.17 1.52 1.28 1.15 .87 .68
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Trim21
KLA  ATP  ATP+KLA
 NM_009277 tripartite motif-containing 21 (Trim21), transcript variant 1, mRNA [NM_009277] KLA 14.42 12.43 14.50 10.28 6.89 5.87 1.97
ATP 1.20 1.00 .91 .53 .61 3.72 2.27
KLA/ATP 13.52 12.88 13.08 10.06 11.82 11.18 9.24
Trove2
KLA  ATP  ATP+KLA
 NM_013835 TROVE domain family, member 2 (Trove2), mRNA [NM_013835] KLA 1.03 .98 .93 .85 .56 .56 .69
ATP 1.01 1.11 1.19 .98 .62 .76 .93
KLA/ATP .97 .96 .95 .83 .60 .60 .70