Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Rheumatoid arthritis (mmu05323)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Acp5
KLA  ATP  ATP+KLA
 NM_007388 acid phosphatase 5, tartrate resistant (Acp5), transcript variant 3, mRNA [NM_007388] KLA 3.62 3.55 3.27 3.26 3.31 3.93 5.79
ATP .96 1.00 1.29 1.96 2.30 3.05 3.81
KLA/ATP 3.61 3.85 4.05 5.38 4.56 5.15 6.77
Angpt1
KLA  ATP  ATP+KLA
 NM_009640 angiopoietin 1 (Angpt1), mRNA [NM_009640] KLA 1.19 1.24 1.37 1.49 1.45 1.20 .99
ATP 1.02 1.05 1.03 1.05 1.04 1.01 1.06
KLA/ATP 1.21 1.23 1.33 1.36 1.30 1.21 1.07
Atp6ap1
KLA  ATP  ATP+KLA
 NM_018794 ATPase, H+ transporting, lysosomal accessory protein 1 (Atp6ap1), mRNA [NM_018794] KLA .73 .83 .89 .71 .74 .71 1.06
ATP 1.05 1.08 .94 1.12 .99 .79 1.07
KLA/ATP .90 .81 .72 .84 .62 .64 .97
Atp6v0a1
KLA  ATP  ATP+KLA
 AK045877 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230316H04 product:unclassifiable, full insert sequence [AK045877] KLA .65 .64 .58 .48 .57 .46 .29
ATP .64 .28 .48 .28 .45 .30 .91
KLA/ATP .51 .26 .37 .31 .54 .45 .63
Atp6v0a1
KLA  ATP  ATP+KLA
 NM_016920 ATPase, H+ transporting, lysosomal V0 subunit A1 (Atp6v0a1), mRNA [NM_016920] KLA .88 .91 .88 .80 .66 .52 .45
ATP 1.05 1.22 .91 1.05 .58 .40 1.46
KLA/ATP .97 1.04 .80 .89 .55 .43 .75
Atp6v0a2
KLA  ATP  ATP+KLA
 AK160318 16 days embryo lung cDNA, RIKEN full-length enriched library, clone:8430408C20 product:unclassifiable, full insert sequence [AK160318] KLA 1.21 1.13 1.18 1.30 1.39 1.58 1.38
ATP 1.10 .94 .55 .35 .72 .96 .84
KLA/ATP 1.12 1.08 .82 .54 .81 1.05 .59
Atp6v0a2
KLA  ATP  ATP+KLA
 BC112905 ATPase, H+ transporting, lysosomal V0 subunit A2, mRNA (cDNA clone MGC:118073 IMAGE:3670722), complete cds [BC112905] KLA 1.65 1.66 1.74 2.07 1.97 2.78 2.71
ATP .88 .61 .53 .30 .38 1.26 2.12
KLA/ATP 1.38 1.29 .91 .62 .59 1.36 2.13
Atp6v0a2
KLA  ATP  ATP+KLA
 NM_011596 ATPase, H+ transporting, lysosomal V0 subunit A2 (Atp6v0a2), mRNA [NM_011596] KLA 2.26 2.07 2.01 2.71 2.48 3.69 2.76
ATP .79 .64 .62 .42 .62 2.31 3.11
KLA/ATP 1.69 1.57 1.47 .90 1.06 2.56 4.84
Atp6v0a4
KLA  ATP  ATP+KLA
 NM_080467 ATPase, H+ transporting, lysosomal V0 subunit A4 (Atp6v0a4), mRNA [NM_080467] KLA 1.01 1.00 .99 1.03 1.01 1.02 .98
ATP 1.02 1.05 .93 1.03 1.05 1.01 .97
KLA/ATP 1.02 .94 1.00 .99 1.00 1.01 1.03
Atp6v0b
KLA  ATP  ATP+KLA
 NM_033617 ATPase, H+ transporting, lysosomal V0 subunit B (Atp6v0b), mRNA [NM_033617] KLA .91 1.00 1.07 .81 1.25 1.34 1.44
ATP 1.12 1.33 .80 1.41 1.47 1.67 1.77
KLA/ATP 1.20 1.16 .62 1.28 1.01 1.77 2.37
Atp6v0c
KLA  ATP  ATP+KLA
 NM_009729 ATPase, H+ transporting, lysosomal V0 subunit C (Atp6v0c), mRNA [NM_009729] KLA .89 .98 1.05 .90 1.18 1.38 1.52
ATP 1.07 1.28 .93 1.66 1.48 1.35 2.35
KLA/ATP 1.10 1.12 .67 1.50 1.18 1.66 2.51
Atp6v0d1
KLA  ATP  ATP+KLA
 NM_013477 ATPase, H+ transporting, lysosomal V0 subunit D1 (Atp6v0d1), mRNA [NM_013477] KLA .84 .85 .94 .79 1.10 1.24 1.27
ATP 1.18 1.48 .94 1.40 1.12 .75 1.85
KLA/ATP 1.05 1.06 .59 1.06 .83 .85 1.96
Atp6v0d2
KLA  ATP  ATP+KLA
 NM_175406 ATPase, H+ transporting, lysosomal V0 subunit D2 (Atp6v0d2), mRNA [NM_175406] KLA .77 .72 .64 .54 .43 .27 .18
ATP 1.19 1.35 1.06 1.47 1.46 .79 .96
KLA/ATP .78 .95 .63 1.12 1.21 1.01 .50
Atp6v0e
KLA  ATP  ATP+KLA
 AK134836 adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330589P19 product:ATPase, H+ transporting, V0 subunit, full insert sequence. [AK134836] KLA 1.09 1.06 1.02 1.42 1.32 1.14 .92
ATP .93 1.18 1.02 1.34 1.72 1.34 1.44
KLA/ATP .97 .89 .94 1.32 2.01 1.43 1.72
Atp6v0e
KLA  ATP  ATP+KLA
 NM_025272 ATPase, H+ transporting, lysosomal V0 subunit E (Atp6v0e), mRNA [NM_025272] KLA 1.00 .95 .87 .99 .98 1.20 1.26
ATP .91 .98 1.11 1.17 1.29 1.54 1.59
KLA/ATP .86 .94 1.07 1.05 1.29 1.57 1.83
Atp6v0e2
KLA  ATP  ATP+KLA
 NM_133764 ATPase, H+ transporting, lysosomal V0 subunit E2 (Atp6v0e2), mRNA [NM_133764] KLA .98 .93 .90 .99 .88 .90 .92
ATP 1.08 1.02 1.03 1.07 .98 .88 .94
KLA/ATP .98 .99 .97 1.00 .89 .90 .88
Atp6v1a
KLA  ATP  ATP+KLA
 NM_007508 ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), mRNA [NM_007508] KLA .77 .77 .70 .59 .58 .61 .84
ATP 1.04 1.45 .99 1.82 1.34 1.00 1.21
KLA/ATP .82 .97 .55 1.13 .73 .99 1.09
Atp6v1b1
KLA  ATP  ATP+KLA
 NM_134157 ATPase, H+ transporting, lysosomal V1 subunit B1 (Atp6v1b1), mRNA [NM_134157] KLA 1.00 1.03 1.11 .95 1.01 1.00 1.03
ATP 1.02 1.05 1.01 .97 1.02 .97 1.02
KLA/ATP .98 .94 1.03 1.02 .99 1.00 .96
Atp6v1b2
KLA  ATP  ATP+KLA
 NM_007509 ATPase, H+ transporting, lysosomal V1 subunit B2 (Atp6v1b2), mRNA [NM_007509] KLA .89 .98 1.11 1.07 1.24 1.13 1.12
ATP 1.05 1.11 1.02 1.09 1.03 .79 1.39
KLA/ATP .97 1.05 .95 1.12 1.12 1.37 1.67
Atp6v1c1
KLA  ATP  ATP+KLA
 NM_025494 ATPase, H+ transporting, lysosomal V1 subunit C1 (Atp6v1c1), mRNA [NM_025494] KLA .61 .62 .59 .51 .56 .71 .92
ATP .98 .97 .93 1.07 1.42 1.00 1.28
KLA/ATP .61 .57 .48 .57 1.04 1.18 1.18
Atp6v1c2
KLA  ATP  ATP+KLA
 NM_133699 ATPase, H+ transporting, lysosomal V1 subunit C2 (Atp6v1c2), mRNA [NM_133699] KLA 1.00 .93 .98 .97 1.04 .99 .97
ATP 1.07 .97 .99 .97 .97 1.04 1.06
KLA/ATP 1.01 1.03 1.00 1.03 1.00 .91 .97
Atp6v1d
KLA  ATP  ATP+KLA
 NM_023721 ATPase, H+ transporting, lysosomal V1 subunit D (Atp6v1d), mRNA [NM_023721] KLA 1.45 1.39 1.73 1.95 1.83 2.08 1.29
ATP .91 .88 1.19 1.12 1.73 1.64 2.34
KLA/ATP 1.25 1.32 1.80 1.46 2.05 2.00 2.22
Atp6v1e1
KLA  ATP  ATP+KLA
 NM_007510 VATPase, H+ transporting, lysosomal V1 subunit E1 (Atp6v1e1), mRNA [NM_007510] KLA 1.48 1.55 1.79 1.73 1.79 1.59 1.37
ATP .88 .73 .59 .73 1.30 1.59 1.40
KLA/ATP 1.50 1.43 1.24 1.30 1.57 1.69 1.76
Atp6v1e2
KLA  ATP  ATP+KLA
 NM_029121 ATPase, H+ transporting, lysosomal V1 subunit E2 (Atp6v1e2), mRNA [NM_029121] KLA 1.01 1.04 1.11 1.14 1.19 1.15 1.11
ATP 1.00 .97 1.11 1.06 1.07 1.02 1.08
KLA/ATP 1.03 1.10 1.19 1.10 1.13 1.06 1.09
Atp6v1f
KLA  ATP  ATP+KLA
 NM_025381 ATPase, H+ transporting, lysosomal V1 subunit F (Atp6v1f), mRNA [NM_025381] KLA .92 .94 .93 .96 .96 1.02 1.05
ATP .97 .96 1.07 1.18 1.31 1.16 1.11
KLA/ATP .92 .96 1.06 1.12 1.28 1.24 1.14
Atp6v1g1
KLA  ATP  ATP+KLA
 NM_024173 ATPase, H+ transporting, lysosomal V1 subunit G1 (Atp6v1g1), mRNA [NM_024173] KLA .97 .94 .87 .99 .98 1.01 .96
ATP 1.02 1.02 1.09 1.10 1.29 1.23 1.41
KLA/ATP .83 .92 1.12 1.10 1.23 1.04 .97
Atp6v1g2
KLA  ATP  ATP+KLA
 NM_023179 ATPase, H+ transporting, lysosomal V1 subunit G2 (Atp6v1g2), mRNA [NM_023179] KLA 1.12 1.09 1.03 1.05 1.16 1.15 1.01
ATP .96 1.01 .93 1.06 .85 .83 1.05
KLA/ATP 1.04 1.07 .99 1.07 .90 .82 .98
Atp6v1g3
KLA  ATP  ATP+KLA
 NM_177397 ATPase, H+ transporting, lysosomal V1 subunit G3 (Atp6v1g3), mRNA [NM_177397] KLA 1.05 1.03 1.00 .99 .97 1.02 1.00
ATP 1.04 1.07 1.02 .98 1.05 1.00 1.00
KLA/ATP .99 .98 1.01 1.02 1.03 1.01 1.05
Atp6v1h
KLA  ATP  ATP+KLA
 AK081492 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130021C16 product:hypothetical V-ATPase subunit H containing protein, full insert sequence. [AK081492] KLA 1.09 .98 .77 .93 1.08 1.00 1.10
ATP 1.16 1.43 2.03 3.91 3.02 1.23 1.46
KLA/ATP 1.02 .98 1.06 2.30 2.07 1.28 1.06
Atp6v1h
KLA  ATP  ATP+KLA
 NM_133826 ATPase, H+ transporting, lysosomal V1 subunit H (Atp6v1h), mRNA [NM_133826] KLA 1.13 1.15 1.12 1.05 1.05 .96 1.20
ATP 1.04 1.04 .86 1.06 2.07 2.38 1.90
KLA/ATP 1.14 1.17 .98 1.09 1.55 2.06 1.29
Ccl12
KLA  ATP  ATP+KLA
 NM_011331 chemokine (C-C motif) ligand 12 (Ccl12), mRNA [NM_011331] KLA 40.77 33.71 46.23 51.22 57.13 57.92 16.26
ATP 1.41 1.14 1.54 1.79 1.41 1.89 9.34
KLA/ATP 39.52 43.18 61.96 69.72 62.95 38.70 29.25
Ccl2
KLA  ATP  ATP+KLA
 NM_011333 chemokine (C-C motif) ligand 2 (Ccl2), mRNA [NM_011333] KLA 10.26 9.30 8.35 10.02 8.92 14.08 11.59
ATP 1.62 1.68 2.20 4.16 3.92 4.84 17.45
KLA/ATP 10.09 10.31 10.95 12.32 8.00 10.04 21.29
Ccl20
KLA  ATP  ATP+KLA
 NM_016960 chemokine (C-C motif) ligand 20 (Ccl20), mRNA [NM_016960] KLA 1.00 1.03 1.05 .98 1.02 1.06 1.08
ATP .98 1.01 1.05 1.11 1.04 1.03 1.02
KLA/ATP 1.06 .97 1.04 1.19 1.02 1.14 1.07
Ccl3
KLA  ATP  ATP+KLA
 NM_011337 chemokine (C-C motif) ligand 3 (Ccl3), mRNA [NM_011337] KLA 22.83 22.40 18.03 21.58 11.57 8.28 7.46
ATP 3.19 4.67 12.12 16.50 11.13 9.49 6.12
KLA/ATP 20.09 20.92 34.53 24.06 21.64 12.34 7.43
Ccl5
KLA  ATP  ATP+KLA
 M77747 rantes mRNA, complete cds. [M77747] KLA 63.18 60.41 56.25 63.63 58.00 66.51 67.20
ATP .91 1.08 1.25 1.90 4.34 16.10 26.07
KLA/ATP 55.92 63.34 72.91 65.68 70.81 71.97 81.34
Ccl5
KLA  ATP  ATP+KLA
 NM_013653 chemokine (C-C motif) ligand 5 (Ccl5), mRNA [NM_013653] KLA 40.31 35.22 27.92 38.59 29.29 37.98 28.83
ATP .86 .92 1.43 1.66 3.86 15.09 16.66
KLA/ATP 32.14 31.72 47.19 35.89 42.00 46.15 43.89
Cd28
KLA  ATP  ATP+KLA
 NM_007642 CD28 antigen (Cd28), mRNA [NM_007642] KLA .52 .51 .45 .50 .36 .33 .18
ATP 1.11 1.26 1.08 1.25 1.99 1.42 2.08
KLA/ATP .51 .51 .58 .60 .56 .53 .38
Cd80
KLA  ATP  ATP+KLA
 NM_009855 CD80 antigen (Cd80), mRNA [NM_009855] KLA 2.13 1.91 1.89 1.78 1.29 1.00 .82
ATP .99 1.20 1.98 1.49 1.37 2.40 1.71
KLA/ATP 2.05 2.32 3.09 2.27 1.95 2.89 3.07
Cd86
KLA  ATP  ATP+KLA
 NM_019388 CD86 antigen (Cd86), mRNA [NM_019388] KLA 13.80 14.41 18.21 18.33 17.37 17.26 4.82
ATP 1.02 1.00 2.20 3.64 5.16 6.79 3.81
KLA/ATP 14.80 14.66 18.10 18.96 19.38 20.42 14.21
Csf1
KLA  ATP  ATP+KLA
 NM_007778 colony stimulating factor 1 (macrophage) (Csf1), transcript variant 1, mRNA [NM_007778] KLA 18.44 16.94 15.74 12.71 7.63 6.20 2.51
ATP 1.04 1.22 4.90 14.80 12.10 10.26 6.73
KLA/ATP 16.93 18.17 20.56 19.41 18.03 15.99 12.59
Csf2
KLA  ATP  ATP+KLA
 NM_009969 colony stimulating factor 2 (granulocyte-macrophage) (Csf2), mRNA [NM_009969] KLA 1.44 1.53 1.38 1.37 1.15 1.21 1.14
ATP 1.01 1.02 1.85 9.73 2.64 1.90 1.14
KLA/ATP 1.49 1.84 2.14 2.80 1.67 1.36 1.35
Ctla4
KLA  ATP  ATP+KLA
 NM_009843 cytotoxic T-lymphocyte-associated protein 4 (Ctla4), mRNA [NM_009843] KLA 1.00 1.04 1.01 1.01 .97 1.01 1.09
ATP 1.01 .98 1.06 .96 .96 .98 1.03
KLA/ATP 1.05 1.06 1.02 .90 .99 .99 1.02
Ctsk
KLA  ATP  ATP+KLA
 NM_007802 cathepsin K (Ctsk), mRNA [NM_007802] KLA 1.02 1.14 1.16 1.37 1.40 1.95 2.05
ATP 1.04 1.06 1.34 2.32 3.59 8.92 14.36
KLA/ATP 1.08 1.23 1.62 2.29 4.63 15.04 24.14
Ctsl
KLA  ATP  ATP+KLA
 NM_009984 cathepsin L (Ctsl), mRNA [NM_009984] KLA .85 .79 .72 .80 .79 .84 .75
ATP 1.02 1.01 1.16 .87 1.73 3.14 6.44
KLA/ATP .72 .80 1.12 .89 1.20 2.53 3.79
Cxcl12
KLA  ATP  ATP+KLA
 NM_001012477 chemokine (C-X-C motif) ligand 12 (Cxcl12), transcript variant 3, mRNA [NM_001012477] KLA .91 .91 .92 .92 .91 1.00 .85
ATP 1.00 .99 1.02 .99 .91 .93 .88
KLA/ATP .89 .91 .97 .97 .94 .93 .82
Cxcl12
KLA  ATP  ATP+KLA
 NM_021704 chemokine (C-X-C motif) ligand 12 (Cxcl12), transcript variant 1, mRNA [NM_021704] KLA 1.01 .96 1.04 1.04 .94 .98 .94
ATP 1.01 .92 .98 1.04 1.02 .94 .98
KLA/ATP 1.02 .98 1.07 .95 1.02 .98 .99
Cxcl5
KLA  ATP  ATP+KLA
 NM_009141 chemokine (C-X-C motif) ligand 5 (Cxcl5), mRNA [NM_009141] KLA 1.27 1.29 1.18 1.21 1.14 1.07 1.08
ATP 1.02 .99 1.08 1.10 1.92 18.34 20.38
KLA/ATP 1.27 1.26 1.26 1.24 1.23 4.06 29.52
EG629860
KLA  ATP  ATP+KLA
 M17953 gb|Mouse Ig rearranged H-chain V-region mRNA VJ1 [M17953] KLA .96 1.05 1.03 1.08 1.08 1.02 .98
ATP .97 .99 1.05 1.10 .95 .94 .91
KLA/ATP .96 .94 .97 1.04 .97 1.01 .89
Flt1
KLA  ATP  ATP+KLA
 NM_010228 FMS-like tyrosine kinase 1 (Flt1), mRNA [NM_010228] KLA 3.02 2.74 2.92 3.54 3.71 3.82 1.43
ATP .88 .85 1.07 .85 .94 1.31 1.16
KLA/ATP 2.60 2.99 3.08 2.13 2.23 2.00 2.59
Fos
KLA  ATP  ATP+KLA
 NM_010234 FBJ osteosarcoma oncogene (Fos), mRNA [NM_010234] KLA .42 .33 .64 .61 .71 .85 .71
ATP 3.48 5.46 23.78 25.22 1.71 2.36 1.50
KLA/ATP .90 1.74 5.97 8.62 1.28 2.42 4.52
H2-Aa
KLA  ATP  ATP+KLA
 NM_010378 histocompatibility 2, class II antigen A, alpha (H2-Aa), mRNA [NM_010378] KLA 1.43 1.59 1.68 1.50 1.62 1.89 1.64
ATP 1.07 1.15 1.27 1.90 1.92 1.77 1.55
KLA/ATP 1.62 1.81 1.74 2.29 1.89 1.92 2.19
H2-Ab1
KLA  ATP  ATP+KLA
 BC010322 histocompatibility 2, class II antigen A, beta 1, mRNA (cDNA clone MGC:6297 IMAGE:2651058), complete cds [BC010322] KLA 1.73 1.76 1.77 1.55 1.95 2.10 2.27
ATP 1.03 1.18 1.32 1.99 1.79 1.56 1.61
KLA/ATP 1.70 2.01 1.74 2.52 1.58 2.01 2.75
H2-Ab1
KLA  ATP  ATP+KLA
 NM_207105 histocompatibility 2, class II antigen A, beta 1 (H2-Ab1), mRNA [NM_207105] KLA 2.02 2.15 2.07 2.09 2.32 2.78 3.08
ATP 1.11 1.20 1.42 2.33 2.33 2.25 1.87
KLA/ATP 2.11 2.32 2.52 3.62 2.67 2.96 5.04
H2-DMa
KLA  ATP  ATP+KLA
 NM_010386 histocompatibility 2, class II, locus DMa (H2-DMa), mRNA [NM_010386] KLA 1.49 1.50 1.65 1.65 1.91 2.23 1.69
ATP 1.04 1.12 1.26 1.67 1.24 .99 1.32
KLA/ATP 1.58 1.68 1.70 2.02 1.37 1.35 1.90
H2-DMb1
KLA  ATP  ATP+KLA
 NM_010387 histocompatibility 2, class II, locus Mb1 (H2-DMb1), mRNA [NM_010387] KLA 1.06 1.14 1.08 1.13 1.24 1.41 1.37
ATP 1.01 1.02 1.09 1.14 .92 .73 1.36
KLA/ATP 1.13 1.05 1.21 1.17 .98 .83 1.41
H2-DMb2
KLA  ATP  ATP+KLA
 NM_010388 histocompatibility 2, class II, locus Mb2 (H2-DMb2), mRNA [NM_010388] KLA 1.00 1.04 .93 .95 .96 .95 1.03
ATP 1.06 1.04 .94 .92 .97 .95 1.00
KLA/ATP .90 .94 .99 .94 .90 .96 .92
H2-Eb1
KLA  ATP  ATP+KLA
 X52641 gb|Mouse mRNA for I-A beta NOD. [X52641] KLA 1.94 2.06 1.94 1.87 1.96 2.18 1.76
ATP 1.11 1.20 1.53 2.70 3.02 2.91 1.40
KLA/ATP 2.09 2.11 2.26 3.55 2.76 3.05 3.05
H2-Oa
KLA  ATP  ATP+KLA
 NM_008206 histocompatibility 2, O region alpha locus (H2-Oa), mRNA [NM_008206] KLA 1.22 1.32 1.37 1.33 1.31 1.26 1.53
ATP 1.02 1.05 1.16 1.21 1.12 1.07 1.16
KLA/ATP 1.32 1.34 1.31 1.34 1.25 1.35 2.78
H2-Ob
KLA  ATP  ATP+KLA
 NM_010389 histocompatibility 2, O region beta locus (H2-Ob), mRNA [NM_010389] KLA 1.05 1.07 1.01 .96 1.10 1.02 1.00
ATP 1.04 .99 1.00 1.03 .94 1.07 .94
KLA/ATP 1.02 .97 1.06 1.08 1.00 .96 1.05
Icam1
KLA  ATP  ATP+KLA
 BC008626 intercellular adhesion molecule, mRNA (cDNA clone MGC:6195 IMAGE:3588949), complete cds [BC008626] KLA 36.67 32.93 28.63 27.91 14.65 8.16 4.15
ATP .96 .88 1.50 3.88 4.98 3.90 1.01
KLA/ATP 32.58 31.60 42.74 32.60 26.00 13.02 6.01
Icam1
KLA  ATP  ATP+KLA
 NM_010493 intercellular adhesion molecule 1 (Icam1), mRNA [NM_010493] KLA 15.66 15.20 12.96 12.31 9.39 6.17 3.81
ATP .96 1.06 1.21 4.19 4.33 3.16 1.06
KLA/ATP 14.31 15.46 17.84 17.60 13.77 8.36 5.42
Ifng
KLA  ATP  ATP+KLA
 NM_008337 interferon gamma (Ifng), mRNA [NM_008337] KLA 1.05 1.02 1.01 1.01 1.01 1.04 1.00
ATP 1.00 1.01 1.01 .98 .97 1.04 1.03
KLA/ATP 1.01 1.01 1.06 1.10 1.24 1.10 1.04
Igh-VJ55
8
KLA  ATP  ATP+KLA
 AY547436 immunoglobulin heavy chain VDJ region mRNA, partial cds [AY547436] KLA 1.06 1.05 1.01 .93 1.03 .96 .93
ATP .99 1.00 1.06 .95 .96 1.06 1.05
KLA/ATP .98 .94 1.07 .95 .97 .99 1.02
Igh-VJ55
8
KLA  ATP  ATP+KLA
 CA578712 gb|K0727F04-5N NIA Mouse Hematopoietic Stem Cell (Lin- [CA578712] KLA .99 .94 1.01 1.10 .93 .97 .92
ATP .93 1.04 1.01 .98 1.05 .96 .95
KLA/ATP .99 .95 .95 .98 1.02 .98 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103412 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHA] [ENSMUST00000103412] KLA 1.01 .97 1.20 1.01 .98 1.44 1.24
ATP .99 .98 1.07 1.03 1.00 1.01 1.21
KLA/ATP .99 1.02 .96 1.03 .97 1.13 1.30
Igh-VJ55
8
KLA  ATP  ATP+KLA
 ENSMUST00000103413 ens|Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHE] [ENSMUST00000103413] KLA 1.00 .99 1.06 1.06 .99 1.03 1.02
ATP 1.08 1.06 1.06 1.06 1.02 1.06 .95
KLA/ATP 1.00 1.04 1.09 1.02 1.06 1.02 .95
Igh-VJ55
8
KLA  ATP  ATP+KLA
 U39781 J558+ IgM heavy chain mRNA, hybridoma clone ME2B7, partial cds. [U39781] KLA .93 .89 .98 .97 1.03 1.00 .94
ATP 1.04 1.02 1.08 .94 .93 .90 .79
KLA/ATP .88 .89 .97 .93 .88 .92 .82
Il11
KLA  ATP  ATP+KLA
 NM_008350 interleukin 11 (Il11), mRNA [NM_008350] KLA .98 1.04 1.03 1.03 .96 1.01 1.02
ATP .94 .97 1.07 1.15 1.18 1.19 1.09
KLA/ATP 1.03 1.10 1.06 1.29 1.72 2.17 1.23
Il15
KLA  ATP  ATP+KLA
 AB022307 mRNA for shorter isoform of interleukin 15, partial cds. [AB022307] KLA 13.11 12.14 12.05 8.72 4.50 3.62 1.70
ATP 1.04 1.05 1.94 1.72 1.74 3.48 1.69
KLA/ATP 13.23 13.71 21.01 21.43 21.51 10.85 4.55
Il15
KLA  ATP  ATP+KLA
 NM_008357 interleukin 15 (Il15), mRNA [NM_008357] KLA 28.44 24.75 23.34 20.83 11.02 7.27 2.51
ATP 1.00 .96 1.22 1.21 1.24 4.27 1.85
KLA/ATP 24.24 23.93 33.47 31.76 21.73 10.79 11.23
Il17a
KLA  ATP  ATP+KLA
 NM_010552 interleukin 17A (Il17a), mRNA [NM_010552] KLA 1.25 1.09 .98 1.02 1.00 .93 .94
ATP 1.01 1.06 1.07 .97 .99 1.09 1.04
KLA/ATP .94 1.00 .99 .99 .99 .84 1.02
Il18
KLA  ATP  ATP+KLA
 NM_008360 interleukin 18 (Il18), mRNA [NM_008360] KLA 12.14 11.96 12.28 12.96 12.23 7.84 2.40
ATP 1.06 .96 1.13 1.04 .92 1.67 2.29
KLA/ATP 11.55 11.63 13.03 9.98 9.08 6.50 6.72
Il1a
KLA  ATP  ATP+KLA
 NM_010554 interleukin 1 alpha (Il1a), mRNA [NM_010554] KLA 32.45 35.22 31.30 20.95 28.57 18.36 19.02
ATP 1.04 1.02 2.21 5.46 11.06 32.07 3.40
KLA/ATP 32.02 41.20 35.12 46.91 28.76 42.72 57.80
Il1b
KLA  ATP  ATP+KLA
 NM_008361 interleukin 1 beta (Il1b), mRNA [NM_008361] KLA 149.78 133.59 100.91 116.58 86.48 89.37 64.72
ATP 3.49 13.96 61.44 70.91 82.12 162.79 28.18
KLA/ATP 130.32 139.00 219.12 148.17 165.44 172.57 146.98
Il23a
KLA  ATP  ATP+KLA
 NM_031252 interleukin 23, alpha subunit p19 (Il23a), mRNA [NM_031252] KLA 1.36 1.46 1.33 1.20 1.05 1.04 1.02
ATP .99 1.01 1.06 1.36 1.25 1.07 1.02
KLA/ATP 1.52 1.62 1.48 1.60 1.23 1.12 1.07
Il6
KLA  ATP  ATP+KLA
 NM_031168 interleukin 6 (Il6), mRNA [NM_031168] KLA 352.99 378.70 276.81 168.47 59.99 18.66 8.27
ATP 1.04 1.08 2.28 3.69 30.40 161.93 2.11
KLA/ATP 334.28 528.66 ###.## 935.86 302.45 355.36 99.65
Itgal
KLA  ATP  ATP+KLA
 AK156251 activated spleen cDNA, RIKEN full-length enriched library, clone:F830013L17 product:integrin alpha L, full insert sequence [AK156251] KLA 5.36 5.78 4.86 5.55 7.02 8.63 11.12
ATP .99 1.17 1.22 1.57 1.35 1.95 3.79
KLA/ATP 5.42 5.89 4.95 5.91 3.96 4.93 10.15
Itgal
KLA  ATP  ATP+KLA
 NM_008400 integrin alpha L (Itgal), mRNA [NM_008400] KLA 4.48 5.17 5.28 5.82 7.82 8.09 16.96
ATP 1.03 1.06 1.24 1.44 1.34 2.02 4.59
KLA/ATP 4.71 5.63 5.49 5.60 3.66 4.65 17.76
Itgb2
KLA  ATP  ATP+KLA
 NM_008404 integrin beta 2 (Itgb2), mRNA [NM_008404] KLA .78 .78 .97 .74 1.04 .94 1.14
ATP 1.24 1.23 .79 .95 1.12 .84 1.10
KLA/ATP .99 1.01 .60 .83 .78 .73 .99
Itgb2l
KLA  ATP  ATP+KLA
 NM_008405 integrin beta 2-like (Itgb2l), mRNA [NM_008405] KLA .87 .98 .98 1.00 1.05 1.07 1.10
ATP 1.24 1.23 1.13 1.14 1.29 1.05 1.05
KLA/ATP 1.02 1.08 1.08 1.06 .98 .93 .95
Jun
KLA  ATP  ATP+KLA
 NM_010591 Jun oncogene (Jun), mRNA [NM_010591] KLA 1.08 .96 1.09 1.09 .75 .88 .81
ATP 1.26 1.48 4.45 8.73 4.02 1.16 1.99
KLA/ATP 1.12 1.38 3.52 5.17 3.32 .49 1.42
Ltb
KLA  ATP  ATP+KLA
 NM_008518 lymphotoxin B (Ltb), mRNA [NM_008518] KLA 2.41 2.52 2.49 3.05 3.54 4.63 1.94
ATP 1.00 .92 1.28 1.57 1.77 1.64 .98
KLA/ATP 2.22 2.68 2.81 3.15 4.88 4.53 2.01
Mm.25500
3
KLA  ATP  ATP+KLA
 161484596 Unknown KLA .35 .34 .35 .34 .22 .19 .10
ATP 1.09 1.27 1.13 1.29 2.25 1.66 2.22
KLA/ATP .38 .36 .39 .40 .49 .42 .32
Mm.38049
KLA  ATP  ATP+KLA
 118130391 Unknown KLA .67 .65 .73 .92 .63 .81 .76
ATP .93 .92 1.08 .54 .45 1.48 1.56
KLA/ATP .57 .65 .98 .67 .44 .78 1.16
Mm.8983
KLA  ATP  ATP+KLA
 77627742 Unknown KLA .89 .94 .87 .83 .73 .60 .41
ATP 1.02 1.06 1.14 1.28 1.11 .76 .55
KLA/ATP 1.00 .98 1.03 1.19 1.01 .70 .54
Mmp1a
KLA  ATP  ATP+KLA
 NM_032006 matrix metallopeptidase 1a (interstitial collagenase) (Mmp1a), mRNA [NM_032006] KLA 1.02 1.04 1.01 1.00 1.05 1.04 1.09
ATP .93 .99 1.07 1.13 1.04 1.05 1.05
KLA/ATP 1.01 1.02 .88 1.01 1.05 1.03 .98
Mmp3
KLA  ATP  ATP+KLA
 NM_010809 matrix metallopeptidase 3 (Mmp3), mRNA [NM_010809] KLA 1.02 1.04 1.04 1.04 .99 1.04 .97
ATP 1.00 1.01 .99 1.01 1.12 3.52 2.55
KLA/ATP 1.01 1.07 .99 .99 .99 1.11 1.16
Tcirg1
KLA  ATP  ATP+KLA
 NM_016921 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 (Tcirg1), mRNA [NM_016921] KLA 1.32 1.42 1.49 1.38 1.94 2.26 1.98
ATP 1.01 1.16 .69 .96 1.24 1.32 2.03
KLA/ATP 1.50 1.58 .90 1.29 1.37 2.08 3.28
Tek
KLA  ATP  ATP+KLA
 AK053336 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130010K24 product:endothelial-specific receptor tyrosine kinase, full insert sequence. [AK053336] KLA .93 .98 .93 .90 .96 1.01 1.10
ATP 1.01 .97 .93 .99 .91 .98 .99
KLA/ATP 1.02 1.06 .95 .93 .92 .91 .92
Tek
KLA  ATP  ATP+KLA
 NM_013690 endothelial-specific receptor tyrosine kinase (Tek), mRNA [NM_013690] KLA 1.00 .95 1.02 .93 .98 .97 1.06
ATP 1.05 1.07 1.01 1.05 .98 1.08 1.13
KLA/ATP .94 .96 1.03 1.11 1.15 .99 1.25
Tgfb1
KLA  ATP  ATP+KLA
 NM_011577 transforming growth factor, beta 1 (Tgfb1), mRNA [NM_011577] KLA .87 .89 .90 .70 .83 .77 1.12
ATP 1.20 1.41 .80 1.49 1.11 .93 .99
KLA/ATP 1.10 1.20 .53 1.05 .66 .85 .90
Tgfb2
KLA  ATP  ATP+KLA
 NM_009367 transforming growth factor, beta 2 (Tgfb2), mRNA [NM_009367] KLA 1.01 .91 .98 .98 .92 1.19 .96
ATP .99 1.03 1.00 1.02 .99 1.07 .93
KLA/ATP 1.02 .99 1.03 .98 1.04 1.06 .96
Tgfb3
KLA  ATP  ATP+KLA
 NM_009368 transforming growth factor, beta 3 (Tgfb3), mRNA [NM_009368] KLA .67 .64 .58 .56 .49 .52 .61
ATP .90 .92 1.33 1.08 .78 .65 .74
KLA/ATP .58 .60 .74 .61 .76 1.36 1.51
Tlr2
KLA  ATP  ATP+KLA
 NM_011905 toll-like receptor 2 (Tlr2), mRNA [NM_011905] KLA 13.65 11.82 8.87 7.95 4.67 2.78 2.33
ATP 1.06 1.24 2.76 6.28 11.55 13.82 .67
KLA/ATP 13.11 12.91 14.48 13.84 14.18 11.14 2.78
Tlr4
KLA  ATP  ATP+KLA
 NM_021297 toll-like receptor 4 (Tlr4), mRNA [NM_021297] KLA .69 .61 .75 .94 .64 .81 .73
ATP .95 .90 1.12 .56 .47 1.51 1.53
KLA/ATP .57 .62 1.01 .64 .39 .73 1.13
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Tnfrsf11
a
KLA  ATP  ATP+KLA
 NM_009399 tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a), mRNA [NM_009399] KLA 1.43 1.33 1.36 1.58 1.87 1.83 1.47
ATP 1.07 1.17 1.02 1.19 .95 .82 1.13
KLA/ATP 1.55 1.46 1.16 1.46 .79 .95 1.92
Tnfsf11
KLA  ATP  ATP+KLA
 NM_011613 tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11), mRNA [NM_011613] KLA 1.00 1.00 1.08 .96 .97 1.01 .96
ATP 1.01 1.05 .97 .86 1.05 1.03 1.01
KLA/ATP 1.04 1.05 .99 1.04 1.01 1.02 .99
Tnfsf12-
tnfsf13
KLA  ATP  ATP+KLA
 NM_001034097 tumor necrosis factor (ligand) superfamily, member 12-member 13 (Tnfsf12-tnfsf13), transcript variant 1, mRNA [NM_001034097] KLA .74 .74 .73 .64 .54 .42 .35
ATP .96 .99 1.06 1.25 1.11 .94 .61
KLA/ATP .76 .77 .76 .99 .86 .82 .55
Tnfsf13b
KLA  ATP  ATP+KLA
 ENSMUST00000033892 ens|Tumor necrosis factor ligand superfamily member 13B (B cell-activating factor) (BAFF) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]. [ KLA .95 .99 .93 .92 .94 .94 .92
ATP .90 .92 1.01 .91 .93 .95 .92
KLA/ATP .94 .89 1.17 1.03 .98 .93 .90
Tnfsf13b
KLA  ATP  ATP+KLA
 NM_033622 tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b), mRNA [NM_033622] KLA .87 .87 .92 .79 .74 .80 1.17
ATP .97 .87 .83 .81 .79 .57 .38
KLA/ATP .91 .86 .87 .88 1.02 .89 .49
Vegfa
KLA  ATP  ATP+KLA
 NM_001025250 vascular endothelial growth factor A (Vegfa), transcript variant 1, mRNA [NM_001025250] KLA .49 .48 .46 .46 .39 .64 1.18
ATP 1.05 1.37 3.82 10.55 12.51 24.20 7.85
KLA/ATP .48 .59 1.45 7.42 19.75 27.42 22.35
Vegfa
KLA  ATP  ATP+KLA
 NM_001025257 vascular endothelial growth factor A (Vegfa), transcript variant 3, mRNA [NM_001025257] KLA .72 .71 .66 .70 .65 .80 1.22
ATP 1.01 1.21 3.24 11.12 11.09 18.59 5.43
KLA/ATP .68 .71 1.47 5.94 15.06 20.32 17.31